WO2011002814A3 - Sulfonamido - biphenyloxyacetic acid compounds - Google Patents
Sulfonamido - biphenyloxyacetic acid compounds Download PDFInfo
- Publication number
- WO2011002814A3 WO2011002814A3 PCT/US2010/040482 US2010040482W WO2011002814A3 WO 2011002814 A3 WO2011002814 A3 WO 2011002814A3 US 2010040482 W US2010040482 W US 2010040482W WO 2011002814 A3 WO2011002814 A3 WO 2011002814A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sulfonamido
- acid compounds
- general formula
- biphenyloxyacetic
- biphenyloxyacetic acid
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
Abstract
Some embodiments of the present invention include novel phenoxyacetic acids useful for the prevention and treatment of inflammatory disorders, including those affecting the respiratory system and skin. Some compounds provided include those of the general formula (I), and compounds of general formula (Ia).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22189909P | 2009-06-30 | 2009-06-30 | |
US61/221,899 | 2009-06-30 |
Publications (2)
Publication Number | Publication Date |
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WO2011002814A2 WO2011002814A2 (en) | 2011-01-06 |
WO2011002814A3 true WO2011002814A3 (en) | 2011-05-26 |
Family
ID=43067187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2010/040482 WO2011002814A2 (en) | 2009-06-30 | 2010-06-29 | Biaryl oxyacetic acid compounds |
Country Status (1)
Country | Link |
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WO (1) | WO2011002814A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2013104506A (en) | 2010-07-05 | 2014-08-10 | Актелион Фармасьютиклз Лтд | 1-Phenyl-substituted heterocyclyl derivatives and their use as modulators of the prostaglandin receptor D2 |
EP2794563B1 (en) | 2011-12-21 | 2017-02-22 | Actelion Pharmaceuticals Ltd | Heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
EP2885307A1 (en) | 2012-07-05 | 2015-06-24 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004000762A2 (en) * | 2002-06-20 | 2003-12-31 | Smithkline Beecham Corporation | Propionic acid derivatives and their use as hppars activators |
WO2004058164A2 (en) * | 2002-12-20 | 2004-07-15 | Tularik, Inc. | Asthma and allergic inflammation modulators |
WO2005105727A1 (en) * | 2004-05-04 | 2005-11-10 | Novartis Ag | Crth2 receptor antagonists |
WO2010102154A2 (en) * | 2009-03-05 | 2010-09-10 | Ligand Pharmaceuticals Incorporated | Biaryl oxyacetic acid compounds |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005102338A1 (en) | 2004-04-20 | 2005-11-03 | Pfizer Limited | Method of treating neuropathic pain using a crth2 receptor antagonist |
-
2010
- 2010-06-29 WO PCT/US2010/040482 patent/WO2011002814A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004000762A2 (en) * | 2002-06-20 | 2003-12-31 | Smithkline Beecham Corporation | Propionic acid derivatives and their use as hppars activators |
WO2004058164A2 (en) * | 2002-12-20 | 2004-07-15 | Tularik, Inc. | Asthma and allergic inflammation modulators |
WO2005105727A1 (en) * | 2004-05-04 | 2005-11-10 | Novartis Ag | Crth2 receptor antagonists |
WO2010102154A2 (en) * | 2009-03-05 | 2010-09-10 | Ligand Pharmaceuticals Incorporated | Biaryl oxyacetic acid compounds |
Non-Patent Citations (1)
Title |
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MAIS D ET AL: "Thromboxane A2 receptor antagonists. Synthesis and activities of phenylsulfonamido derivatives", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 26, no. 8, 1 November 1991 (1991-11-01), pages 821 - 827, XP023870492, ISSN: 0223-5234, [retrieved on 19911101], DOI: DOI:10.1016/0223-5234(91)90009-C * |
Also Published As
Publication number | Publication date |
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WO2011002814A2 (en) | 2011-01-06 |
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