WO2010148394A1 - Herbal supplement - Google Patents

Herbal supplement Download PDF

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Publication number
WO2010148394A1
WO2010148394A1 PCT/US2010/039345 US2010039345W WO2010148394A1 WO 2010148394 A1 WO2010148394 A1 WO 2010148394A1 US 2010039345 W US2010039345 W US 2010039345W WO 2010148394 A1 WO2010148394 A1 WO 2010148394A1
Authority
WO
WIPO (PCT)
Prior art keywords
extracts
herbal supplement
cordyceps sinensis
group consisting
cinnamomum cassia
Prior art date
Application number
PCT/US2010/039345
Other languages
French (fr)
Inventor
Agnes P. Olszewski
James P. Gilligan
Original Assignee
Olszewski Agnes P
Gilligan James P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US21881909P priority Critical
Priority to US61/218,819 priority
Application filed by Olszewski Agnes P, Gilligan James P filed Critical Olszewski Agnes P
Publication of WO2010148394A1 publication Critical patent/WO2010148394A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/235Foeniculum (fennel)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda

Abstract

Natural herbal supplements are provided for enhancing energy and/or sexual potency. Combinations of natural agents include, for example, eucommia ulmoides, cynomorium songaricum, morinda officinalis, panax ginseng, and/or epimedium brevicornum. Some embodiments include cinnamomum cassia, cordyceps sinensis and/or foeniculum vulgare.

Description

HERBAL SUPPLEMENT

CROSS REFERENCE TQ RELATED APPLICATION(S1

The present application claims priority of U.S. Provisional Application No. 61/218,819 filed June 19, 2009, the contents of which are all incorporated herein by reference.

BACKGROUND OF THE INVENTION

Field of the Invention

The present invention relates to natural herbal supplements for enhancing energy and/or sexual potency, and in particular to certain combinations of natural agents that include, for example, eucommia ulmoides, cynomorium songaricum, morinda officinalis, panax ginseng, and/or epimedium brevicornum.

Description of the Related Art

Various herbs have long been used by various cultures, for example in traditional Chinese Medicine techniques that date back for centuries. For example, Epimidium brevicornum has been recommended for relieving fatigue, boosting sex drive (libido), increasing energy levels and enhancing recovery from strenuous exercise.

Hong Jing Tian in (Rhodiola rosea) has been recognized as an adaptogen - - a substance that non-specifϊcally increases the resistance of an organism and does not disturb normal biological parameters. Hong Jin Tian has been cited in scientific articles for its adaptogenic, anti-stress, neuroendocrine, cardio-protective, antioxidant and anti-carcinogenic effects while bringing support to sexual functions.

01 152827 1 Several herbs have been reported to stimulate, support and strengthen the sexual organs. For example, epimedium, cynomorri, cistanche, morindae, eucommia, cuscutae and cinnamon are reported to possess strengthening and stimulating properties which enhance sex drive.

Prescription erectile dysfunction products are based upon inhibiting an enzyme in the body called phosphodi-esterase (PDE-5). Under normal conditions sexual stimuli cause a local release of Nitrous Oxide (NO) which in turn stimulates a second messenger (cGMP) which dilates blood vessels in the penis leading to an erection. To turn off this signal PDE-5 breaks down the cGMP to terminate the action. By inhibiting this enzyme (PDE-5), prescription products prolong the effect of cGMP allowing more blood to flow into the caverns of the penis. Because other blood vessels of the body may be similarly affected, these products may be contraindicated for patients with the following underlying conditions:

* Patients who have suffered a Myocardial Infarction (heart attack), stroke, or life threatening arrhythmias

* Patients with resting hypotension (90/50) or hypertension (170/110)

* Patients with cardiac failure or Coronary Artery Disease (CAD)

* Patients with unstable angina

* Patients with retinitis

There is a need in the art to for natural products that can better promote energy and sexual health while avoiding some of the side effects of prescription pharmaceuticals.

SUMMARY OF THE INVENTION

It is an object of the present invention to provide an herbal elixer helpful in promoting or maintaining energy.

01 152827.1 It is another object of the present invention to provide an herbal elixer helpful in promoting or maintaining sexual health.

In one embodiment, the invention provides an herbal supplement in the form of an aqueous elixer comprising extracts of at least three (and sometimes all four) agents selected from the group consisting of eucommia ulmoides, cynomorium songaricum, morinda officinalis, and epimedium brevicornum.

In another embodiment, the invention provides an herbal supplement in the form of an aqueous elixer comprising extracts of at least four (and sometimes all five) agents selected from the group consisting of eucommia ulmoides, cynomorium songaricum, morinda officinalis, panax ginseng and epimedium brevicornum.

In another embodiment, the invention provides an herbal supplement in the form of an aqueous elixer comprising extracts of epimedium brevicornum and of at least two additional agents selected from the group consisting of eucommia ulmoides, cynomorium songaricum and morinda officinalis.

In some embodiments, each of the foregoing embodiments may further include extracts of at least two (and sometimes all three) agents selected from the group consisting of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.

The multiple ingredients present in the formulations of the invention are expected to provide a focused synergistic effect on a man's sexual response and at the same time provide overall energy to sustain this response. The experience gathered over many years for most of the ingredients discussed herein creates an expectation of a good safety profile.

0U 52827. I - A -

Other features and advantages of the present invention will become apparent from the following non-limiting description of preferred embodiments of the invention.

DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS OF THE INVENTION

In many preferred embodiments, extracts of epimedium are utilized. Without intending to be bound by theory, it is believed that epimedium provides benefits via modulation of Cortisol levels (a primary stress hormone). Under conditions of high physical stress, the increased Cortisol levels are believed to cause fatigue and depress sex drive. Thus, bringing Cortisol levels back into normal ranges is also believed to help restore normal metabolism, energy levels and libido.

According to traditional Chinese techniques, fortification of kidney energy and function may improve sexual stamina and performance while restoring vitality, energy and endurance. Some of the highly enriched ingredients of the present invention include agents which may be implicated in the maintenance of kidney health, thereby improving erections and strengthening and enhancing sexual functions in healthy males by a kidney-mediated mechanism, and may reduce symptoms for those who experience temporary or long term sexual dysfunction caused by stress, environmental or medical conditions.

The combination of Siberian Ginseng, Codonopsis and Red Ginseng, when used, is expected to provide the body with increased vitality and endurance important for sexual stamina. These longevity and energy herbs are believed to strengthen the system and be restorative to the body, helping to increase its efficiency. As a result they may help to direct more blood to the genitals and other erotically stimulated zones.

An example of an herbal extract in accordance with the invention, and of its method of manufacture is set forth below.

01 152827.1 EXAMPLE

A preferred all- natural herbal supplement of the invention is manufactured in a GMP compliant facility. Manufacturing begins by admixing the ingredients set forth below in the relative amounts set forth in the last column below. Thereafter the ingredients undergo extraction and preparation into an elixer in accordance with the technique set forth infra.

Ingredients Relative amount

Eucommia ulmoides 8

Cynomorium songaricum 8

Morinda officinalis 8

Panax ginseng 10

Epimedium brevicornum 8

Cinnamomum cassia 2

Cuscuta chinensis 6

Rehmannia glutinosa 8

Cordyceps sinensis 4

Lycium barbarum 4

Polygonum multiflorum 6

Schisandra chinensis 4

Achyranthes bidentata 6

Foeniculum vulgare 2

Bupleurum chinense 2

Ziziphus jujuba 2

Rhodiola rosea 6

01 152827 1 Extraction Process for the Production of the Elixir

Place the pre-mixed herb material (1 kg) in a round bottom flask of appropriate size, add 3 litres of 50% ethanol (the other 50% water). Carry out heated extraction under reflux for an additional 2 hours. Cool the content in the flask to room temperature and pour out the ethanol solution (Solution I). To the herb residue in the flask, add 2 litres of 50% ethanol and reflux for an additional 2 hours. Cool the content in the flask to room temperature and pour out the ethanol solution (Solution II). Combine Solutions I and II. Recover ethanol from the combined solution by distillation to reduce the volume of the solution to about 2.5 litres. Adjust the ethanol content to around 20% and the volume to 3.5 litres and stand at room temperature for 24 hours. Filter through cotton wool. Add 20% ethanol to the filtrate to make the final volume tol US Gallon (3.781itres). The solution is ready to be bottled.

Recommended daily dosage of the foregoing elixer is between 6 and 18 milliliters, e,g. about 10 milliliters.

Although the present invention has been described in relation to particular embodiments thereof, many other variations and modifications and other uses will become apparent to those skilled in the art. It is preferred, therefore, that the present invention be limited not by the specific disclosure herein, but only by the appended claims.

01152827 1

Claims

WHAT IS CLAIMED IS:
1. An herbal supplement in the form of an aqueous elixer comprising extracts of at least three agents selected from the group consisting of eucommia ulmoides, cynomorium songaricum, morinda officinalis, and epimedium brevicornum.
2. An herbal supplement in the form of an aqueous elixer comprising extracts of at least four agents selected from the group consisting of eucommia ulmoides, cynomorium songaricum, morinda officinalis panax ginseng and epimedium brevicornum.
3. An herbal supplement in the form of an aqueous elixer comprising extracts of epimedium brevicornum and of at least two additional agents selected from the group consisting of eucommia ulmoides, cynomorium songaricum and morinda officinalis.
4. The herbal supplement of claim 3 having extracts of each of eucommia ulmoides, cynomorium songaricum and morinda officinalis.
5. The herbal supplement of claim 1 further comprising extracts of at least two agents selected from the group consisting of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
6. The herbal supplement of claim 2 further comprising extracts of at least two agents selected from the group consisting of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
01152827 1
7. The herbal supplement of claim 3 further comprising extracts of at least two agents selected from the group consisting of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
8. The herbal supplement of claim 4 further comprising extracts of at least two agents selected from the group consisting of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
9. The herbal supplement of claim 1 further comprising extracts of each of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
10. The herbal supplement of claim 2 further comprising extracts of each of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
11. The herbal supplement of claim 3 further comprising extracts of each of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
12. The herbal supplement of claim 4 further comprising extracts of each of cinnamomum cassia, cordyceps sinensis and foeniculum vulgare.
01152827 1
PCT/US2010/039345 2009-06-19 2010-06-21 Herbal supplement WO2010148394A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US21881909P true 2009-06-19 2009-06-19
US61/218,819 2009-06-19

Publications (1)

Publication Number Publication Date
WO2010148394A1 true WO2010148394A1 (en) 2010-12-23

Family

ID=43356790

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/039345 WO2010148394A1 (en) 2009-06-19 2010-06-21 Herbal supplement

Country Status (1)

Country Link
WO (1) WO2010148394A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102894014A (en) * 2012-11-01 2013-01-30 彭万喜 Method for preparing woody antibacterial agent
CN103210847A (en) * 2013-05-02 2013-07-24 甘肃凯源生物技术开发中心 In-vitro embryo cultivation method for measuring vitality of cynomorium seeds

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020031559A1 (en) * 2000-03-08 2002-03-14 Liang Kin C. Herbal suppositories
US20030157208A1 (en) * 2001-12-20 2003-08-21 Rui Wang Cynomoriaceae extract and use in treating erectile dysfunction
US20040142001A1 (en) * 2003-01-16 2004-07-22 Kuok Koon Yong Herbal compositions for prostate conditions
US20040161524A1 (en) * 2001-06-21 2004-08-19 Yasushi Sakai Process for producing a plant extract containing plant powder
US20060210657A1 (en) * 2001-07-17 2006-09-21 Chou Wen H Compositions and methods for prostate and kidney health and disorders, an herbal preparation
US20070041993A1 (en) * 2003-05-29 2007-02-22 Holcomb-Halstead Terri L Compositions and methods for symptomatic relief
US20070059386A1 (en) * 2005-09-12 2007-03-15 Tsun-Nin Lee Modular system for novel Chinese herbal formulas
US20070259058A1 (en) * 2006-05-04 2007-11-08 Rulin Xiu Morinda herbal extracts and compositions thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020031559A1 (en) * 2000-03-08 2002-03-14 Liang Kin C. Herbal suppositories
US20040161524A1 (en) * 2001-06-21 2004-08-19 Yasushi Sakai Process for producing a plant extract containing plant powder
US20060210657A1 (en) * 2001-07-17 2006-09-21 Chou Wen H Compositions and methods for prostate and kidney health and disorders, an herbal preparation
US20030157208A1 (en) * 2001-12-20 2003-08-21 Rui Wang Cynomoriaceae extract and use in treating erectile dysfunction
US20040142001A1 (en) * 2003-01-16 2004-07-22 Kuok Koon Yong Herbal compositions for prostate conditions
US20070041993A1 (en) * 2003-05-29 2007-02-22 Holcomb-Halstead Terri L Compositions and methods for symptomatic relief
US20070059386A1 (en) * 2005-09-12 2007-03-15 Tsun-Nin Lee Modular system for novel Chinese herbal formulas
US20070259058A1 (en) * 2006-05-04 2007-11-08 Rulin Xiu Morinda herbal extracts and compositions thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102894014A (en) * 2012-11-01 2013-01-30 彭万喜 Method for preparing woody antibacterial agent
CN102894014B (en) * 2012-11-01 2015-02-18 彭万喜 Method for preparing woody antibacterial agent
CN103210847A (en) * 2013-05-02 2013-07-24 甘肃凯源生物技术开发中心 In-vitro embryo cultivation method for measuring vitality of cynomorium seeds

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