WO2010143200A3 - A coronary stent with nano coating of drug free polymer and a process for preparation thereof - Google Patents

A coronary stent with nano coating of drug free polymer and a process for preparation thereof

Info

Publication number
WO2010143200A3
WO2010143200A3 PCT/IN2010/000370 IN2010000370W WO2010143200A3 WO 2010143200 A3 WO2010143200 A3 WO 2010143200A3 IN 2010000370 W IN2010000370 W IN 2010000370W WO 2010143200 A3 WO2010143200 A3 WO 2010143200A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
stent
nano
coronary
coated
coating
Prior art date
Application number
PCT/IN2010/000370
Other languages
French (fr)
Other versions
WO2010143200A2 (en )
Inventor
S. Sundar Manoharan
T. R. Muralidharan
Original Assignee
Indian Institute Of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/12Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/04Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases

Abstract

The present invention relates to a medical device carrying a nano coating by utilizing the same on the coronary stent systems and a process for preparation thereof. The inventive coronary stents can be provided with various advantages/properties and properties thereof. The material coated is a biocompatible bio-formulation which by means of a physical vapor deposition route ensures a very thin coating (5 to 40 nm). In-vitro studies on human blood suggest that, the nano coated stent is devoid of platelet adhesion. Such a hydrophobic nano coated stent surface reduces the chances of thrombosis as a result it provides a viable alternative to drug eluting stents.
PCT/IN2010/000370 2009-06-11 2010-06-04 A coronary stent with nano coating of drug free polymer and a process for preparation thereof WO2010143200A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN1197/DEL/2009 2009-06-11
IN1197DE2009 2009-06-11

Publications (2)

Publication Number Publication Date
WO2010143200A2 true WO2010143200A2 (en) 2010-12-16
WO2010143200A3 true true WO2010143200A3 (en) 2011-03-17

Family

ID=42754874

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2010/000370 WO2010143200A3 (en) 2009-06-11 2010-06-04 A coronary stent with nano coating of drug free polymer and a process for preparation thereof

Country Status (1)

Country Link
WO (1) WO2010143200A3 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142579A1 (en) * 2006-06-05 2007-12-13 Bactiguard Ab A polymer matrix, uses thereof and a method of manufacturing the same
US20090118813A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Nano-patterned implant surfaces

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466509A (en) 1993-01-15 1995-11-14 Impra, Inc. Textured, porous, expanded PTFE
DK0621015T3 (en) 1993-04-23 1998-12-21 Schneider Europ Gmbh Stent but a cover layer of an elastic material and a method for depositing this layer on the stent
DE69428282D1 (en) 1993-08-18 2001-10-18 Gore & Ass Thin-walled, seamless, porous polytetrafluoroäthylenrohr
US5888591A (en) 1996-05-06 1999-03-30 Massachusetts Institute Of Technology Chemical vapor deposition of fluorocarbon polymer thin films
US6364903B2 (en) 1999-03-19 2002-04-02 Meadox Medicals, Inc. Polymer coated stent
US8435287B2 (en) 2004-03-30 2013-05-07 Toyo Advanced Technologies Co., Ltd. Stent and method for fabricating the same
EP1804958A4 (en) 2004-09-17 2010-11-17 Nanosys Inc Nanostructured thin films and their uses
US20060129215A1 (en) 2004-12-09 2006-06-15 Helmus Michael N Medical devices having nanostructured regions for controlled tissue biocompatibility and drug delivery
US8263104B2 (en) 2007-06-08 2012-09-11 Northwestern University Polymer nanofilm coatings
US20090104244A1 (en) 2007-09-21 2009-04-23 Boston Scientific Scimed, Inc. Therapeutic agent-eluting medical devices having textured polymeric surfaces
US20090104434A1 (en) 2007-10-17 2009-04-23 Jennifer Hoyt Lalli Conformal multifunctional coatings

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142579A1 (en) * 2006-06-05 2007-12-13 Bactiguard Ab A polymer matrix, uses thereof and a method of manufacturing the same
US20090118813A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Nano-patterned implant surfaces

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
K. P. GRYTSENKO, S. SCHRADER: "Nanoclusters in polymer matrices prepared by co-deposition from a gas phase", ADVANCES IN COLLID AND INTERFACE SCIENCE, vol. 116, 19 October 2005 (2005-10-19), pages 263-276, XP002615548, *
LIU ZHIJIAN, LE XIAOYUN, JIANG XINGLIU, HAN LIJUN: "Preparation of nanometer thin films with intense pulsed electron beam ablation", SURFACE AND COATINGS TECHNOLOGY, 2005, pages 325-328, XP002615544, *

Also Published As

Publication number Publication date Type
WO2010143200A2 (en) 2010-12-16 application

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