WO2010142739A1 - Use of substituted oxindole derivatives for the treatment and prophylaxis of pain - Google Patents
Use of substituted oxindole derivatives for the treatment and prophylaxis of pain Download PDFInfo
- Publication number
- WO2010142739A1 WO2010142739A1 PCT/EP2010/058107 EP2010058107W WO2010142739A1 WO 2010142739 A1 WO2010142739 A1 WO 2010142739A1 EP 2010058107 W EP2010058107 W EP 2010058107W WO 2010142739 A1 WO2010142739 A1 WO 2010142739A1
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- WIPO (PCT)
- Prior art keywords
- methoxy
- hydrogen
- methyl
- ethoxy
- ethyl
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2763931A CA2763931A1 (en) | 2009-06-10 | 2010-06-09 | Use of substituted oxindole derivatives for the treatment and prophylaxis of pain |
CN2010800359565A CN102573836A (en) | 2009-06-10 | 2010-06-09 | Use of substituted oxindole derivatives for the treatment and prophylaxis of pain |
EP10721526A EP2440202A1 (en) | 2009-06-10 | 2010-06-09 | Use of substituted oxindole derivatives for the treatment and prophylaxis of pain |
MX2011013324A MX2011013324A (en) | 2009-06-10 | 2010-06-09 | Use of substituted oxindole derivatives for the treatment and prophylaxis of pain. |
JP2012514468A JP2012529468A (en) | 2009-06-10 | 2010-06-09 | Use of substituted oxindole derivatives for the treatment and prevention of pain |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US18577809P | 2009-06-10 | 2009-06-10 | |
US61/185,778 | 2009-06-10 |
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WO2010142739A1 true WO2010142739A1 (en) | 2010-12-16 |
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PCT/EP2010/058107 WO2010142739A1 (en) | 2009-06-10 | 2010-06-09 | Use of substituted oxindole derivatives for the treatment and prophylaxis of pain |
Country Status (7)
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---|---|
US (1) | US20110059983A1 (en) |
EP (1) | EP2440202A1 (en) |
JP (1) | JP2012529468A (en) |
CN (1) | CN102573836A (en) |
CA (1) | CA2763931A1 (en) |
MX (1) | MX2011013324A (en) |
WO (1) | WO2010142739A1 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014140186A1 (en) | 2013-03-14 | 2014-09-18 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying an oxetane substituent and use thereof for treating vasopressine-related diseases |
WO2015091931A1 (en) | 2013-12-20 | 2015-06-25 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying a piperidyl-substituted azetidinyl substituent and use thereof for treating vasopressine-related diseases |
WO2015173392A1 (en) | 2014-05-15 | 2015-11-19 | AbbVie Deutschland GmbH & Co. KG | Oxindole compounds carrying a co-bound spiro substituent and use thereof for treating vasopressin-related diseases |
US9273036B2 (en) | 2013-03-14 | 2016-03-01 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying an oxetane substituent and use thereof for treating vasopressine-related diseases |
US9862704B2 (en) | 2013-12-20 | 2018-01-09 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying an amine-substituted piperidyl-acetidinyl substituent and use thereof for treating vasopressine-related diseases |
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- 2010-06-09 CA CA2763931A patent/CA2763931A1/en not_active Abandoned
- 2010-06-09 CN CN2010800359565A patent/CN102573836A/en active Pending
- 2010-06-09 JP JP2012514468A patent/JP2012529468A/en active Pending
- 2010-06-09 WO PCT/EP2010/058107 patent/WO2010142739A1/en active Application Filing
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CA2763931A1 (en) | 2010-12-16 |
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