WO2010133578A3 - Electroporation device with improved tip and electrode support - Google Patents

Electroporation device with improved tip and electrode support Download PDF

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Publication number
WO2010133578A3
WO2010133578A3 PCT/EP2010/056790 EP2010056790W WO2010133578A3 WO 2010133578 A3 WO2010133578 A3 WO 2010133578A3 EP 2010056790 W EP2010056790 W EP 2010056790W WO 2010133578 A3 WO2010133578 A3 WO 2010133578A3
Authority
WO
WIPO (PCT)
Prior art keywords
electroporation
electroporation device
present
electrode
rotationally symmetrical
Prior art date
Application number
PCT/EP2010/056790
Other languages
French (fr)
Other versions
WO2010133578A2 (en
Inventor
Lasse Guldborg Staal
Rune Henri Wincenty Drage
René LARSEN
Original Assignee
Sonion A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sonion A/S filed Critical Sonion A/S
Priority to EP10723007A priority Critical patent/EP2432412A2/en
Publication of WO2010133578A2 publication Critical patent/WO2010133578A2/en
Publication of WO2010133578A3 publication Critical patent/WO2010133578A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The present invention relates to an electroporation device with a distal tip which comprises a rotationally symmetrical member. A set of longitudinally extending tip electrode channels comprises a set of electrode grooves disposed around a circumferential contour of the rotationally symmetrical member. In another aspect of the present invention there is provided an electroporation device with a first and a second set of electrode tubes forming a plurality of telescopic arrangements to support and protect electroporation electrodes. Electroporation devices in accordance with the present inventions are particularly well-suited for performing electroporation in deeper-lying bodily tissues for example tissues of the central nervous system such as brain tissue.
PCT/EP2010/056790 2009-05-20 2010-05-18 Electroporation device with improved tip and electrode support WO2010133578A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10723007A EP2432412A2 (en) 2009-05-20 2010-05-18 Electroporation device with improved tip and electrode support

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17996009P 2009-05-20 2009-05-20
US61/179,960 2009-05-20

Publications (2)

Publication Number Publication Date
WO2010133578A2 WO2010133578A2 (en) 2010-11-25
WO2010133578A3 true WO2010133578A3 (en) 2011-01-13

Family

ID=43125048

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/056790 WO2010133578A2 (en) 2009-05-20 2010-05-18 Electroporation device with improved tip and electrode support

Country Status (3)

Country Link
US (1) US20100298761A1 (en)
EP (1) EP2432412A2 (en)
WO (1) WO2010133578A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5670572B2 (en) * 2010-08-31 2015-02-18 クック メディカル テクノロジーズ エルエルシーＣｏｏｋ Ｍｅｄｉｃａｌ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ Cautery overtube
WO2012052543A1 (en) * 2010-10-22 2012-04-26 Herlev Hospital A method for treating a tissue region with an electric field
CA2837214C (en) 2011-06-28 2021-06-01 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
EP2606845B1 (en) * 2011-12-23 2016-10-26 Lina Medical ApS Pulse generator
WO2013144901A2 (en) * 2012-03-30 2013-10-03 Koninklijke Philips N.V. Nested cannula tips
US9878148B2 (en) * 2012-04-17 2018-01-30 Boston Scientific Neuromodulation Corporation Lead with contact end conductor guide and methods of making and using
US9827413B2 (en) * 2012-04-17 2017-11-28 Boston Scientific Neuromodulation Corporation Lead construction for deep brain stimulation
AU2015236341B2 (en) * 2014-03-24 2020-03-05 Old Dominion University Research Foundation Expandable catheter devices electrode array
JP6592526B2 (en) * 2015-05-11 2019-10-16 セント・ジュード・メディカル，カーディオロジー・ディヴィジョン，インコーポレイテッド High density mapping and ablation catheter
WO2016193403A1 (en) * 2015-06-02 2016-12-08 Oblique Therapeutics Ab Electroporation device
US10561407B2 (en) * 2017-05-05 2020-02-18 Hoya Corporation Apparatuses and methods for endoscopic tool joints
GB2563386A (en) * 2017-06-08 2018-12-19 Creo Medical Ltd Electrosurgical instrument
CN109893244B (en) * 2017-12-08 2024-04-19 Igea有限公司 Manipulation and control system for expandable electrodes of a handpiece for use in electroporation procedures
AU2019263465A1 (en) * 2018-05-02 2020-12-24 Oncosec Medical Incorporated Electroporation systems, methods, and apparatus
US20200129230A1 (en) * 2018-10-24 2020-04-30 Boston Scientific Scimed, Inc. Movable electrodes for controlled irreversible electroporation ablative volumes
AU2019367220A1 (en) * 2018-10-26 2021-06-10 Kytopen Corporation Devices, systems, and kits for electroporation and methods of use thereof
US11660139B2 (en) 2019-04-10 2023-05-30 Radioclash Inc. Electroporation probe
KR102233408B1 (en) * 2019-05-07 2021-03-29 고려대학교 산학협력단 Apparatus for electrically stimulation
TWI815147B (en) * 2020-07-21 2023-09-11 財團法人國家衛生研究院 Method for nucleic acid-based vaccine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0834288A1 (en) * 1996-10-04 1998-04-08 Jeffrey J. Blewett Apparatus for the thermal treatment of tissue
US5782900A (en) * 1997-06-23 1998-07-21 Irvine Biomedical, Inc. Catheter system having safety means
WO2006095171A1 (en) * 2005-03-10 2006-09-14 Emcision Limited Device and method for the treatment of diseased tissue such as tumours
US20070006215A1 (en) * 2005-07-01 2007-01-04 Gordon Epstein Anchored RF ablation device for the destruction of tissue masses
WO2007144004A1 (en) * 2006-06-12 2007-12-21 Region Hovedstaden V/Herlev Hospital Electrode introducer device
US20080208187A1 (en) * 2007-02-22 2008-08-28 Medtronic, Inc. Impedance computation for ablation therapy

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US5536267A (en) * 1993-11-08 1996-07-16 Zomed International Multiple electrode ablation apparatus
WO2002054941A2 (en) * 2001-01-11 2002-07-18 Rita Medical Systems Inc Bone-treatment instrument and method
US6625486B2 (en) * 2001-04-11 2003-09-23 Advanced Cardiovascular Systems, Inc. Method and apparatus for intracellular delivery of an agent
CA2445392C (en) * 2001-05-10 2011-04-26 Rita Medical Systems, Inc. Rf tissue ablation apparatus and method
ATE320767T1 (en) * 2001-09-28 2006-04-15 Rita Medical Systems Inc IMPEDANCE CONTROLLED DEVICE FOR TISSUE ABLATION
US7967816B2 (en) * 2002-01-25 2011-06-28 Medtronic, Inc. Fluid-assisted electrosurgical instrument with shapeable electrode
US6912417B1 (en) * 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US7328064B2 (en) * 2002-07-04 2008-02-05 Inovio As Electroporation device and injection apparatus
US20060036210A1 (en) * 2004-06-30 2006-02-16 Lei Zhang Modular electroporation device with disposable electrode and drug delivery components
US20080058706A1 (en) * 2004-06-30 2008-03-06 Genetronics, Inc. Modular electroporation device with disposable electrode and drug delivery components
US20090062795A1 (en) * 2007-08-31 2009-03-05 Ethicon Endo-Surgery, Inc. Electrical ablation surgical instruments

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0834288A1 (en) * 1996-10-04 1998-04-08 Jeffrey J. Blewett Apparatus for the thermal treatment of tissue
US5782900A (en) * 1997-06-23 1998-07-21 Irvine Biomedical, Inc. Catheter system having safety means
WO2006095171A1 (en) * 2005-03-10 2006-09-14 Emcision Limited Device and method for the treatment of diseased tissue such as tumours
US20070006215A1 (en) * 2005-07-01 2007-01-04 Gordon Epstein Anchored RF ablation device for the destruction of tissue masses
WO2007144004A1 (en) * 2006-06-12 2007-12-21 Region Hovedstaden V/Herlev Hospital Electrode introducer device
US20080208187A1 (en) * 2007-02-22 2008-08-28 Medtronic, Inc. Impedance computation for ablation therapy

Also Published As

Publication number Publication date
EP2432412A2 (en) 2012-03-28
US20100298761A1 (en) 2010-11-25
WO2010133578A2 (en) 2010-11-25

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