WO2010114505A1 - A counter for a dry powder inhaler device - Google Patents

A counter for a dry powder inhaler device Download PDF

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Publication number
WO2010114505A1
WO2010114505A1 PCT/TR2010/000067 TR2010000067W WO2010114505A1 WO 2010114505 A1 WO2010114505 A1 WO 2010114505A1 TR 2010000067 W TR2010000067 W TR 2010000067W WO 2010114505 A1 WO2010114505 A1 WO 2010114505A1
Authority
WO
WIPO (PCT)
Prior art keywords
blister
outer housing
inner body
disposed
actuating element
Prior art date
Application number
PCT/TR2010/000067
Other languages
French (fr)
Inventor
Ahmet Toksoz
Zafer Toksoz
Musa Umit Cifter
Original Assignee
Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi filed Critical Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
Priority to EA201190182A priority Critical patent/EA021559B1/en
Priority to UAA201112674A priority patent/UA107191C2/en
Publication of WO2010114505A1 publication Critical patent/WO2010114505A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043—Non-destructive separation of the package, e.g. peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/0055—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being coiled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0078—Mechanical counters having a display or indicator on a strip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Definitions

  • the present invention relates to inhaler devices allowing administration of dry powder inhalation medicaments, and more particularly to developments conducted on the counter component of such inhaler devices.
  • inhalation devices for administering inhalation medicaments have been proposed until date. These devices are basically classified in two groups, i.e. metered dose inhalers and dry powder inhalers. These type of devices are structurally provided with basic components such as actuator, counter, housing, lid, lock, etc. On the other hand, powder inhalation medicaments are kept in reservoirs or containers such as blisters, capsules, etc. Blisters are structured from two basic parts, a main layer provided with cavities holding the medicament, and a strippable protective layer. It is very crucial with respect to user to meter or count each cavity consumed in devices containing blisters, and a number of counter embodiments of various types have already been proposed for this purpose.
  • One type of the current inhaler devices has the form of a disk, comprising multiple medicament compartments. These compartments comprise medicament cartridges, the medicaments are made ready for use after piercing by means of a needle, and administered by means of a mouthpiece. These devices further contain a disk-shaped counter, such that the number, i.e. numeric figure of consumed medicament cartridges is displayed by means of said counter.
  • WO2008114034, WO2005004962 may be cited herein to exemplify such type of devices.
  • Such devices can take a determined number of medicaments into the disk, so that an increase in the device volume as result of increasing the number of medicaments therein gives rise to a carrying/handling-, aesthetics- and use-related unpleasant outcomes. Additionally, they require the use of extra apparatuses for the counter.
  • the current inhaler devices are provided with various counter systems indicating the amount of consumed medicament powder.
  • Patent applications WO2008110584, WO2005079727, US2003209239 disclose various counter embodiments. Said counter mechanisms comprise multiple components, with many of them having disks which function as a counter. Any malfunctioning of the components in counters can lead to an inaccurate metering of the amount or dose of medicament to be used, resulting in unresponsiveness to treatment, or even in more serious outcomes with respect to the patient. Other undesired outcomes also emerge, such as high costs, larger device volumes, operation-related problems, etc.
  • the present invention relates to a novel inhaler device for use with dry powder inhaling purposes, eliminating all aforesaid problems and brining additional advantages to the relevant prior art.
  • the main object of the present invention is to provide a counter embodiment, which is capable of operating accurately in a dry powder inhaler device and allowing easy and accurate display of the numbers on the blister strip out of the device. .
  • Another object of the present invention is to provide a counter embodiment, which allows the blister strip in use to advance in an invariable distance pattern.
  • a further object of the present invention is to provide advantages in terms of cost and device volume, thanks to the present counter embodiment, which eliminates the requirement towards extra elements and components.
  • a dry powder inhaler device comprises an outer housing, an inner body disposed in the outer housing, a reservoir disposed at the lower part of said inner body for receiving an unused blister with enumerated medicament-filled cavities, an actuating element moving the blister by rotating a gear set disposed in the inner body once said actuating element is slid or pushed into the interior of said outer housing, and a medicament release opening disposed at the upper part of the outer housing on which a mouthpiece is provided.
  • the device for providing an accurate view of, or for accurately displaying, the numbers on a blister from the inhaler device's exterior once said actuating element is pushed into the interior of the outer housing, the device according to the present invention further comprises an outer housing counter display gap disposed at the base part of said outer housing, an inner body counter display gap disposed at the lower part of said inner body so as to come to alignment with the outer housing counter display gap, an actuating element counter display gap disposed at the lower part of said actuating element so as to come to alignment with the inner body counter display gap, and an arc shaped surface piece to form a channel through which the blister is to be passed at the lower part of the inner body and to keep the blister at a desired stretched extent in said channel.
  • a positioning distance between the number of each cavity on the blister and the cavity of that respective number is provided a positioning distance between the number of each cavity on the blister and the cavity of that respective number, this positioning distance being as large as the distance between the medicament release opening and the window formed by the counter display gaps.
  • one of the display gaps is provided with a lens magnifying the view of the blister.
  • Figure 1 is an exploded schematic view of an illustrative embodiment according to the present invention.
  • Figure 2 is a perspective schematic view of the inner body according to the present invention.
  • Figure 3 is a cross-sectional schematic view of the subject inhaler device with a blister inserted.
  • Figure 4 is an illustrative view of the base part of the subject inhaler device.
  • Figure 5 is a cross-sectional schematic view of the counter display gaps and the reservoir of the subject inhaler device. Reference Numbers in Figures
  • the outer housing (1) of the inhaler device according to the present invention is made by assembling parts of the outer housing to each other, said housing having mutually-fitting structures and provided with fastening tabs at their periphery.
  • the upper part of said outer housing (1) is provided with a medicament release opening (3.1) and a mouthpiece (3) disposed on said opening, so that the medicament included therein can be inhaled by a user.
  • a lid (7) is provided, which preferably can be rotated as a result of being pivoted on the outer housing (1) and which can be closed so as to cover the mouthpiece (3) in order to keep clean said mouthpiece (3) when the inhaler device (6) is not in use and to prevent any unwanted substances from entering into the device (6).
  • An inner body (2) is positioned in the interior of the outer housing (1), as illustrated in perspective in Figure 2.
  • the lower part of said inner body (2) is embodied with a reservoir (2.3), into which an unused blister (4) is placed, said blister having medicament-filled cavities (4.1).
  • An arc shaped surface piece (2.1) with a semicircular shape is formed at the lower part of the inner body (2) for producing a channel through which a blister (4) can be passed, whereas an opening, referred to herein as the inner body counter display gap (2.2), is produced on the inner body surface (2) under said piece (2.1).
  • the other parts of said inner body (2) are in turn equipped with a gear set (8), which provide for the operation of the inhaler (6). Said gear set (8) also allows moving the blister (4) in one direction only.
  • An actuating element (5) is disposed at the lower lateral part of said outer housing (1), this actuating element being slid between the outer housing (1) and the inner body (2).
  • a rectangular opening is formed at the lower side of the actuating element (5), referred to herein as the actuating element counter display gap (5.1). It is also feasible to dispose a lens at this site in order to optimize the view of the counter. It is possible to embody a counter mechanism which can reliably be used without requiring any additional elements.
  • the openings referred to hereinabove, as the inner body counter display gap (2.2), as the actuating element counter display gap (5.1), and as the outer housing counter display gap (1.1), are superimposed so as to result in a window when the actuating element (5) is depressed, i.e. pushed in, as schematically illustrated in Figure 5. Thanks to this feature, when the device (6) illustrated in Figure 4 is viewed from its base, it becomes possible to see the cover layer, i.e. protective layer of the blister (4) present in the reservoir (2.3) of the inner body (2).
  • the cover layer of the blister (4) is provided with numbers, indicating the sequential numbers of medicaments.
  • the operation of the device (6) according to the present invention is as follows. Following the opening of lid (7), a force is exerted by the user to the grip surface (5.2) of the actuating element (5), thus to the actuating element (5) itself. Then the actuating element (5) is driven or slid or pushed into the interior of the housing (1). When this movement is transferred to the gear set (8) disposed in the inner body (2), the blister (4) is advanced through the channels of this body (2).
  • the relevant number on the blister (4) comes to alignment with the counter display gaps (1.1 , 2.2, 5.1) of the outer housing, inner body, and actuating element, respectively.
  • the user is able to see the number on the blister (4) properly further enabling him/her to see the amount of consumed medicaments by means of the counter mechanism embodied as described above.
  • the blister (4) is kept at a desired stretched extent, so that the numbers come exactly to the same plane with the gaps (1.1 , 2.2, 5.1), thanks to the arc shaped surface piece (2.1) formed at the inner body (2) surface.
  • the numbers, i.e. numeric figures on the blister (4) are accurately read, and the probability of making mistakes is eliminated.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention relates to a device for administering dry powder inhalation medicaments. The present invention further relates to a counter mechanism of a dry powder inhaler device (6), comprising an actuating element (5), which is slid or pushed into the interior of an inner body, so as to move a blister (4) in a single direction, said blister having medicament-carrying cavities being disposed in the interior of an outer housing (1) and directed both to an inner body (2) and to a mouthpiece (3). The strip comprises numbers to indicate the sequential numbers of said blister cavities (4.1), and an arc shaped surface piece (2.1), forming a channel through which the blister (4) is to be passed at the lower part of the inner body (2) and keeping the blister (4) at a desired stretched extent in this channel.

Description

A COUNTER FOR A DRY POWDER INHALER DEVICE
Field of Invention
The present invention relates to inhaler devices allowing administration of dry powder inhalation medicaments, and more particularly to developments conducted on the counter component of such inhaler devices.
Prior Art
Diseases such as asthma, bronchitis, and COLD (Chronic Obstructive Lung Disease) substantially decrease the quality of human life, despite the developments which have been carried out in the diagnosis and therapy thereof in the recent years. It has been proposed to administer medicaments via inhalers for optimizing the treatment of such diseases. The inhaler route of treatment is the most preferred one and it is expected to remain so, as a first option, in the future. The most important advantage of using medicaments via inhalation route is based on providing a more efficient therapy by making use of lesser medicaments, delivering higher concentration of medicaments to the respiration channels, and particularly decreasing the systemic side effects of medicaments. The most important causes of the lack of a satisfactory control of patients albeit the presence of quite efficient treatments against respiratory tract diseases are mentioned to be noncompliance to proper use of inhalers and insufficient obedience to doctor's recommended therapy.
Various inhalation devices for administering inhalation medicaments have been proposed until date. These devices are basically classified in two groups, i.e. metered dose inhalers and dry powder inhalers. These type of devices are structurally provided with basic components such as actuator, counter, housing, lid, lock, etc. On the other hand, powder inhalation medicaments are kept in reservoirs or containers such as blisters, capsules, etc. Blisters are structured from two basic parts, a main layer provided with cavities holding the medicament, and a strippable protective layer. It is very crucial with respect to user to meter or count each cavity consumed in devices containing blisters, and a number of counter embodiments of various types have already been proposed for this purpose.
One type of the current inhaler devices has the form of a disk, comprising multiple medicament compartments. These compartments comprise medicament cartridges, the medicaments are made ready for use after piercing by means of a needle, and administered by means of a mouthpiece. These devices further contain a disk-shaped counter, such that the number, i.e. numeric figure of consumed medicament cartridges is displayed by means of said counter. WO2008114034, WO2005004962 may be cited herein to exemplify such type of devices. Such devices can take a determined number of medicaments into the disk, so that an increase in the device volume as result of increasing the number of medicaments therein gives rise to a carrying/handling-, aesthetics- and use-related unpleasant outcomes. Additionally, they require the use of extra apparatuses for the counter.
The current inhaler devices are provided with various counter systems indicating the amount of consumed medicament powder. Patent applications WO2008110584, WO2005079727, US2003209239 disclose various counter embodiments. Said counter mechanisms comprise multiple components, with many of them having disks which function as a counter. Any malfunctioning of the components in counters can lead to an inaccurate metering of the amount or dose of medicament to be used, resulting in unresponsiveness to treatment, or even in more serious outcomes with respect to the patient. Other undesired outcomes also emerge, such as high costs, larger device volumes, operation-related problems, etc..
The complicated multicomponent structure of many of the existing counters cause application and use-related difficulties and prevent users from obtaining maximum possible efficiency.
In result, there is a need for development in the field of inhaler devices, providing high- accuracy operation, as well as advantages in terms of cost, volume, and usage.
Object and Brief Description of Invention
The present invention relates to a novel inhaler device for use with dry powder inhaling purposes, eliminating all aforesaid problems and brining additional advantages to the relevant prior art.
Accordingly, the main object of the present invention is to provide a counter embodiment, which is capable of operating accurately in a dry powder inhaler device and allowing easy and accurate display of the numbers on the blister strip out of the device. .
Another object of the present invention is to provide a counter embodiment, which allows the blister strip in use to advance in an invariable distance pattern.
A further object of the present invention is to provide advantages in terms of cost and device volume, thanks to the present counter embodiment, which eliminates the requirement towards extra elements and components. A dry powder inhaler device according to the present invention comprises an outer housing, an inner body disposed in the outer housing, a reservoir disposed at the lower part of said inner body for receiving an unused blister with enumerated medicament-filled cavities, an actuating element moving the blister by rotating a gear set disposed in the inner body once said actuating element is slid or pushed into the interior of said outer housing, and a medicament release opening disposed at the upper part of the outer housing on which a mouthpiece is provided. In addition, for providing an accurate view of, or for accurately displaying, the numbers on a blister from the inhaler device's exterior once said actuating element is pushed into the interior of the outer housing, the device according to the present invention further comprises an outer housing counter display gap disposed at the base part of said outer housing, an inner body counter display gap disposed at the lower part of said inner body so as to come to alignment with the outer housing counter display gap, an actuating element counter display gap disposed at the lower part of said actuating element so as to come to alignment with the inner body counter display gap, and an arc shaped surface piece to form a channel through which the blister is to be passed at the lower part of the inner body and to keep the blister at a desired stretched extent in said channel.
In a preferred embodiment according to the present invention, there is provided a positioning distance between the number of each cavity on the blister and the cavity of that respective number, this positioning distance being as large as the distance between the medicament release opening and the window formed by the counter display gaps.
In another preferred embodiment according to the present invention, one of the display gaps is provided with a lens magnifying the view of the blister.
Brief Description of Figures
Figure 1 is an exploded schematic view of an illustrative embodiment according to the present invention.
Figure 2 is a perspective schematic view of the inner body according to the present invention.
Figure 3 is a cross-sectional schematic view of the subject inhaler device with a blister inserted.
Figure 4 is an illustrative view of the base part of the subject inhaler device.
Figure 5 is a cross-sectional schematic view of the counter display gaps and the reservoir of the subject inhaler device. Reference Numbers in Figures
1. Outer housing
1. 1 Outer housing counter display gap
2. Inner body
2. 1 Arc shaped surface piece
2. 2 Inner body counter display gap
2. 3 Reservoir
3. Mouthpiece
3. 1 Medicament release opening
4. Blister
4. 1 Cavity
5. Actuating element
5. 1 Actuating element counter display gap
5. 2 Grip surface
6. Inhaler
7. Lid
8. Gear set
Detailed Description of Invention In the following detailed description, the inhaler device according to the present invention shall be described illustratively by making references to annexed figures, only to make it clear without imposing any restrictions thereon.
The outer housing (1) of the inhaler device according to the present invention, of which an exploded schematic view is given in figures 1 and 3, is made by assembling parts of the outer housing to each other, said housing having mutually-fitting structures and provided with fastening tabs at their periphery. The upper part of said outer housing (1) is provided with a medicament release opening (3.1) and a mouthpiece (3) disposed on said opening, so that the medicament included therein can be inhaled by a user. A lid (7) is provided, which preferably can be rotated as a result of being pivoted on the outer housing (1) and which can be closed so as to cover the mouthpiece (3) in order to keep clean said mouthpiece (3) when the inhaler device (6) is not in use and to prevent any unwanted substances from entering into the device (6). There is also formed an opening, referred to herein as the outer housing counter display gap (1.1), at the lower part of said outer housing (1).
An inner body (2) is positioned in the interior of the outer housing (1), as illustrated in perspective in Figure 2. The lower part of said inner body (2) is embodied with a reservoir (2.3), into which an unused blister (4) is placed, said blister having medicament-filled cavities (4.1). An arc shaped surface piece (2.1) with a semicircular shape is formed at the lower part of the inner body (2) for producing a channel through which a blister (4) can be passed, whereas an opening, referred to herein as the inner body counter display gap (2.2), is produced on the inner body surface (2) under said piece (2.1). The other parts of said inner body (2) are in turn equipped with a gear set (8), which provide for the operation of the inhaler (6). Said gear set (8) also allows moving the blister (4) in one direction only.
An actuating element (5) is disposed at the lower lateral part of said outer housing (1), this actuating element being slid between the outer housing (1) and the inner body (2). A rectangular opening is formed at the lower side of the actuating element (5), referred to herein as the actuating element counter display gap (5.1). It is also feasible to dispose a lens at this site in order to optimize the view of the counter. It is possible to embody a counter mechanism which can reliably be used without requiring any additional elements.
The openings referred to hereinabove, as the inner body counter display gap (2.2), as the actuating element counter display gap (5.1), and as the outer housing counter display gap (1.1), are superimposed so as to result in a window when the actuating element (5) is depressed, i.e. pushed in, as schematically illustrated in Figure 5. Thanks to this feature, when the device (6) illustrated in Figure 4 is viewed from its base, it becomes possible to see the cover layer, i.e. protective layer of the blister (4) present in the reservoir (2.3) of the inner body (2). The cover layer of the blister (4) is provided with numbers, indicating the sequential numbers of medicaments. There is provided, however, a positioning distance between the number of each cavity (4.1) and the cavity (4.1) of that respective number, as large as the distance between the medicament release opening (3.1) and the window formed by the counter display gaps (1.1 , 2.2, 5.1). Thanks to this feature, when the actuating element (5) is depressed, and when the inhaler device (6) is viewed from its base or bottom, the number of the cavity (4.1) now arrived at the medicament release opening (3.1) can be seen. It is possible to make use of different signing or coloring methods in place of using the numeric figures on the blister's (4) protective layer, it being further feasible to apply these signs on the blister (4) by means of printing, labeling, using laser-based or even more advanced methods.
According to the structural details given above, the operation of the device (6) according to the present invention is as follows. Following the opening of lid (7), a force is exerted by the user to the grip surface (5.2) of the actuating element (5), thus to the actuating element (5) itself. Then the actuating element (5) is driven or slid or pushed into the interior of the housing (1). When this movement is transferred to the gear set (8) disposed in the inner body (2), the blister (4) is advanced through the channels of this body (2).
At the same time the relevant number on the blister (4) comes to alignment with the counter display gaps (1.1 , 2.2, 5.1) of the outer housing, inner body, and actuating element, respectively. Thus, the user is able to see the number on the blister (4) properly further enabling him/her to see the amount of consumed medicaments by means of the counter mechanism embodied as described above. During the advancing movement, the blister (4) is kept at a desired stretched extent, so that the numbers come exactly to the same plane with the gaps (1.1 , 2.2, 5.1), thanks to the arc shaped surface piece (2.1) formed at the inner body (2) surface. Thus, the numbers, i.e. numeric figures on the blister (4) are accurately read, and the probability of making mistakes is eliminated.

Claims

1) A dry powder inhaler device (6), comprising an outer housing (1), an inner body (2) disposed in said outer housing (1), a reservoir (2.3) disposed at the lower part of said inner body (2) for receiving unused blister (4) with enumerated medicament-filled cavities (4.1), an actuating element (5) moving the blister (4) by rotating a gear set (8) disposed in the inner body (2) once said actuating element (5) is slid or pushed into the interior of said outer housing (1), and a medicament release opening (3.1) disposed at the upper part of said outer housing (1) over which a mouthpiece (3) is provided; characterized in that the dry powder inhaler device (6) further comprises; an outer housing counter display gap (1.1) disposed at the base part of said outer housing (1), an inner body counter display gap (2.2) disposed at the lower part of said inner body (2) so as to come to alignment with said outer housing counter display gap (1.1), an actuating element counter display gap (5.1) disposed at the lower part of said actuating element (5) so as to come to alignment with said counter display gap (2.2), and an arc shaped surface piece (2.1) forming a channel through which the blister (4) is to be passed at the lower part of said inner body (2) and keeping the blister (4) at a desired stretched extent in said channel. whereby the numeric figures on said blister (4) can be accurately displayed to the exterior of said inhaler device (6) when said actuating element (5) is slid or pushed into the interior of said outer housing (1)
2) A dry powder inhaler device (6) according to Claim 1 , characterized in that a positioning distance is provided between the numeric figure of each cavity (4.1) on the blister (4) and the cavity (4.1) of that respective numeric figure, this positioning distance being as large as the distance between the medicament release opening (3.1) and the window formed by the counter display gaps (1.1 , 2.2, 5.1).
3) A dry powder inhaler device (6) according to any of the preceding claims, characterized in that one of the display gaps (1.1 , 2.2) is provided with a lens which magnifies the appearance of the blister.
PCT/TR2010/000067 2009-03-30 2010-03-30 A counter for a dry powder inhaler device WO2010114505A1 (en)

Priority Applications (2)

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EA201190182A EA021559B1 (en) 2009-03-30 2010-03-30 A counter for a dry powder inhaler device
UAA201112674A UA107191C2 (en) 2009-03-30 2010-03-30 DRY POWDER INHALATOR counter

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EP2666500A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. Inhaler device with an improved blister advancement mechanism
EP2666502A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. An inhaler having a mechanism with double actuating levers
EP2666503A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. An inhaler mechanism having a transmission and a pivot arm
EP2666501A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. Inhaler having an inner body with air channel
EP2666504A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. Blister advancement mechanism comprising an actuator plate
EP2666499A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. A trigger mechanism for an inhaler device
EP2432532B1 (en) * 2009-05-18 2014-07-30 Norton Healthcare Limited Dry-powder inhaler
USD737424S1 (en) * 2013-01-30 2015-08-25 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Button of an inhaler device
USD745138S1 (en) * 2013-01-30 2015-12-08 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Member of an inhaler device
USD855792S1 (en) * 2013-01-30 2019-08-06 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Inhaler device

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Cited By (19)

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EP2432532B1 (en) * 2009-05-18 2014-07-30 Norton Healthcare Limited Dry-powder inhaler
EP2666504A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. Blister advancement mechanism comprising an actuator plate
EP2666501A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. Inhaler having an inner body with air channel
WO2013176641A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi An inhaler having a mechanism with double actuating levers
WO2013176636A1 (en) * 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi A trigger mechanism for inhaler device
EP2666499A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. A trigger mechanism for an inhaler device
WO2013176642A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi An inhaler mechanism having a transmission and a pivot arm
WO2013176643A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Blister advancement mechanism comprising an actuator plate
WO2013176640A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi An inhaler comprising a inner body having an air channel
WO2013176639A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhaler device with an improved blister advancement mechanism
EP2666503A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. An inhaler mechanism having a transmission and a pivot arm
EP2666500A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. Inhaler device with an improved blister advancement mechanism
EP2666502A1 (en) 2012-05-25 2013-11-27 Arven Ilac Sanayi Ve Ticaret A.S. An inhaler having a mechanism with double actuating levers
US10207067B2 (en) 2012-05-25 2019-02-19 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Blister advancement mechanism comprising an actuator plate
EA030019B1 (en) * 2012-05-25 2018-06-29 Арвен Айлак Санайи Ве Тиджарет А.С. Trigger mechanism for inhaler device
US9956362B2 (en) 2012-05-25 2018-05-01 Arven Ilac Saniyi ve Ticaret A.S. Trigger mechanism for inhaler device
USD745138S1 (en) * 2013-01-30 2015-12-08 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Member of an inhaler device
USD737424S1 (en) * 2013-01-30 2015-08-25 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Button of an inhaler device
USD855792S1 (en) * 2013-01-30 2019-08-06 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Inhaler device

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CY1115990T1 (en) 2017-01-25
EP2239003B1 (en) 2014-11-19
DK2239003T3 (en) 2015-02-02
HRP20150151T1 (en) 2015-05-22
SMT201500042B (en) 2015-05-05
PT2239003E (en) 2015-02-16
EA201190182A1 (en) 2012-03-30
EA021559B1 (en) 2015-07-30
EP2239003A1 (en) 2010-10-13
PL2239003T3 (en) 2015-04-30
SI2239003T1 (en) 2015-04-30
ES2530445T3 (en) 2015-03-02

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