WO2010085903A1 - Administering device comprising a holding element for a fluid receptacle - Google Patents

Administering device comprising a holding element for a fluid receptacle Download PDF

Info

Publication number
WO2010085903A1
WO2010085903A1 PCT/CH2009/000035 CH2009000035W WO2010085903A1 WO 2010085903 A1 WO2010085903 A1 WO 2010085903A1 CH 2009000035 W CH2009000035 W CH 2009000035W WO 2010085903 A1 WO2010085903 A1 WO 2010085903A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
component
behälteraufhahme
characterized
delivery device
Prior art date
Application number
PCT/CH2009/000035
Other languages
German (de)
French (fr)
Inventor
Jürg HIRSCHEL
Céline KÄNEL
Ulrich Moser
Markus Tschirren
Original Assignee
Tecpharma Licensing Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecpharma Licensing Ag filed Critical Tecpharma Licensing Ag
Priority to PCT/CH2009/000035 priority Critical patent/WO2010085903A1/en
Publication of WO2010085903A1 publication Critical patent/WO2010085903A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2433Ampoule fixed to ampoule holder
    • A61M2005/2437Ampoule fixed to ampoule holder by clamping means
    • A61M2005/244Ampoule fixed to ampoule holder by clamping means by flexible clip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2433Ampoule fixed to ampoule holder
    • A61M2005/2444Ampoule fixed to ampoule holder by thread
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2488Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M2005/3142Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2066Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod

Abstract

A device for administering a fluid product is disclosed, comprising a housing (1) and a receptacle seat (2) with a receptacle (2). A component (14) is arranged in the housing (1), said component (14) and the receptacle seat (2) being axially movable towards each other. According to the invention, a holding element (15) is releasably disposed on the component in a first position of the receptacle seat (2) relative to the component (14). In a second position, in which the receptacle seat (2) is moved in the direction of the component, the holding element (15) is released from the component (14) and is fastened to the receptacle seat (2) in such a way as to form a holding stop for the receptacle (3) in the receptacle seat (2).

Description

Of administration DEVICE WITH HOLDING ELEMENT FOR

FLUID RESERVOIR

TECHNICAL FIELD

The present invention relates to an administration device for administering a fluid product, in particular an injection device in which a container is secured to a housing by means of a container receptacle, according to the preamble of claim 1.

STATE OF THE ART

Delivery devices for administering a fluid product are widely known in the field of medicine, pharmacy or cosmetics. For example, preparations such as insulin or growth hormones are injected with such delivery devices. As a rule, the delivery devices, or also known as injection pens, a housing in which an administering mechanism is housed. To the housing, a fluid tank can be connected directly or through a container receiving and administering mechanism. Preferably cartridges are used as containers, having a sealed with a septum opening at one end and are closed at the opposite end with a movably mounted plug. There are also known cartridges that have two separated from one another by a second stopper chambers in each of which a component of a fluid product is, the components may be mixed before use in the carpule. For administration of the product from the carpule an injection needle to the carpule or the container receptacle is placed such that it pierces the septum and forms a fluid connection to the interior of the container. The administration mechanism has, for example, a feed member is moved relative to the housing and thereby acts on the stopper of the carpule. By the advance of the plug, the product in the container is poured through the injection needle.

From EP 0829268 a medication dispensing apparatus is known, for example, comprising a housing having a delivery mechanism, which comprises a dosing device for setting a product dosage to be administered and a piston rod which can be displaced axially relative to the housing. To the housing with the mechanical unit is a carpule holder can be connected by means of a threaded connection. The carpule holder can shoot a product container in the form of a carpule having a sliding stopper and sealed by a septum opening in itself. In this case, an opening formed at the front end of the carpule shoulder comes to rest on a counter-stop of the carpule holder and the rear end of the feed member engages the stopper of the carpule. The product container is thus secured to the feed member against axial movement within the carpule holder by the front stop on the container edge and the rear stop. It can be so placed on the carpule holder now a needle assembly such that the septum of the cartridge is pierced. By an advancement of the stopper within the cartridge by means of the piston rod, the product can now be injected from the delivery device.

In such devices, the administration feeding member acts immediately after inserting or already during insertion of the Behälteraufhahme on the stopper in a container. A pressure on the product in the container is already being exercised. When fitting or replacing a hypodermic needle, a small amount of product passes through this pressure already triggered by the injection needle. Upon insertion of the injection needle irritation or irritation of the skin may be caused by this contamination of the injection needle. In addition, this results in a loss of the product, which then is not for administration to a patient.

It is therefore desirable that no pressure is exerted on a plug inside the container when mounting an injection needle unit to a product container or on a Behälteraufhahme with a product container, but the container is still held securely in the Behälteraufhahme so that when mounting an injection needle unit has a fluid connection can be produced reliably to the product in the container. This is particularly relevant in administering devices Mehrkammerkarpulen, in which the administration product is produced only by the advance of the plugs within the container by mixing various components. Often, the plug inside the container is here for feeding a component of the administering mechanism such as using a feed member, to be removed after the mixing of the components and prior to installation of a needle unit of the stopper within the container.

It is therefore an object of the present invention to provide a delivery device in which a container is securely held in a Behälteraufhahme that allows a simple assembly of the individual components of the administration device is not affected by the container contents through the mounting of the container within the device and that is easy to handle.

SUMMARY OF THE INVENTION

This object is achieved by the invention by means of a delivery device according to Claim. 1 Advantageous refinements and embodiments are described in the dependent claims.

A delivery device for administering a fluid product according to the present invention comprises a housing and a container receptacle, in which a container is incorporated with the fluid product. The housing is preferably cylindrical and receives a delivery mechanism into itself. The administration mechanism may include a metering device and a dispenser. The dispenser may include, inter alia, a feed member which is mounted for administering the fluid product from the container relative to the container displaceable in the housing.

In the housing, a component is mounted, which is preferably disposed concentrically within the housing. The component may, for example, by a sleeve, a sleeve segments or a component of the delivery mechanism, are in particular formed by the feed member. The component and the Behälteraufhahme are axially movable towards each other are provided. It can either be fixed relative to the housing and the Behälteraufhahme be moved in the direction of the component or the Behälteraufhahme is fixed relative to the housing and the component is moved towards the Behälteraufhahme the component. It is also possible in principle that both the component and the Behälteraufhahme to move relative to the housing so that the component and the receptacle move toward each other.

According to the present invention, a retaining element is provided which is disposed in a first position of the Behälteraufhahme relative to the component detachably on the component and in a second position in which the Behälteraufhahme is displaced in the direction of the component is detached from the component and at the Behälteraufhahme is such fixed such that it forms a stop for retaining the container in the Behälteraufhahme. The component serves as a carrier component which carries the holding element in the first position. The retaining element is, however, releasably supported on the support member to be placed in the second position to the Behälteraufhahme to. The support member or the retaining element has this z. B. to a breaking point. The retaining element can be connected to the component, such as a feed member, at one end, which faces the the Behälteraufhahme be appropriate. but it can also be located at a remote area relative to the Behälteraufhahme on the component.

In a delivery device of the present invention is a holding element, which is capable of fixing a container in a Behälteraufhahme not directly provided on the Behälteraufhahme, but will only be attached when inserting the Behälteraufhahme in a housing of the administering device at the Behälteraufhahme. Characterized the retaining element when inserting the container into the Behälteraufhahme not interfere, but the container can easily slide into the Behälteraufhahme. The fixing of the container within the Behälteraufhahme by a erfmdungsgemässes holding member not engaged with a stopper in the container and can not take on the product inside the container influence. The holding member engages rather at the edge of the container and can thus keep these safe to Behälteraufhahme. In the illustrated embodiments, it is particularly advantageous that the feed member can be used both as a support member for the retaining element and on the other to feed the plug during the mixing of two components. It is advantageous that the holding element can be moved by means of the feed member towards the container in the container receptacle in a direction opposite movement of the feed member relative to the container receiver, however, detached from and remains on the container receptacle as a retaining stop for the container. Thus, the feed member can be retracted into the containers of the plug for a feed of the stopper, without causing the retaining element is achieved for holding the container in the container receptacle. When attaching an injection needle unit to the recording area of ​​a container receiving no pressure on the feed member on the fluid product inside the container is thus applied so that gas does not leak product while placing the needle unit.

The container receptacle is formed like a sleeve and adapted to receive the container completely in it. As a container, a conventional cartridge may be used made of glass or plastic, having at a forward taper, which adjoins a shoulder of the container when it is inserted into the container receptacle. The taper forms a head portion of the container and has a container opening which is closed by a septum, which is secured by a flanging over the opening. At the opposite end of the container that is closed by a plug movably supported. Between the plug and the closed opening through the septum, the product to be administered is stored in the container. In particular Mehrkammerkarpulen may be used having at least two chambers which are separated from each other by a further plug, and having a bypass for diverting a component from a chamber to the other chamber. If the container is inserted into the container receptacle, preferably is the outer circumference of the container on the inner circumference of the container receptacle to lie, so that the container in the radial direction is held securely.

The container receptacle may comprise a blocking stop that blocks axial movement of the container relative to the container receptacle in an insertion direction of the container into the receptacle. For this purpose the Behälteraufhahme may have an inwardly projecting paragraph, for example, on which a shoulder of the cartridge abuts when it is fully inserted into the Behälteraufhahme. a connection area can be followed by the heel of the Behälteraufhahme which receives the Karpulenkopf with the sealed opening through the Septrum in itself. The connection region of the Behälteraufhahme has a central opening and on its outer circumference a fixing structure may be provided to which a needle unit may be secured. When an injection needle unit is placed on the terminal area, a hypodermic needle held by the unit can protrude through the opening of the connection region and through the septum into the interior of the container and forms a fluid connection.

The Behälteraufhahme can be attached to the end opposite to the connection area to the housing. The container receptacle can be moved into, for example, completely or only with a small area in the housing. Preferably, a guide means between the housing and the Behälteraufhahme is provided which enables a defined positioning of the Behälteraufhahme in the housing. For example, the Behälteraufhahme can be inserted into the housing and engage, for example, in a certain position with the housing. Preferably, however, a thread is provided between the Behälteraufhahme and the housing with which the container receptacle can be screwed into the housing. By screwing the Behälteraufhahme in the housing, a portion of the at least Behälteraufhahme is received within the housing.

The holding member may be annular and is z. B. at one end of the component, such as the feed member, arranged facing the container receptacle. but it can also be located at a remote area relative to the Behälteraufhahme on the component.

If the container receiving axially in the direction of the component, such as moving the feed member is the support member by a stop in the container receptacle, such as the edge of the container is detached from the component, while it can be shifted further relative to the Behälteraufhahme. The container receptacle is preferably at least partially slipped over the component so that the component and the Behälteraufiiahme overlap in the radial direction. The retaining element z. B. provided at a front end of a feed member, which faces the Behälteraufiiahme, the retaining element can be introduced by means of the feed member in the Behälteraufiiahme and be detached from the feed member before the feed member hits the stopper in the container. Alternatively, the retaining element can be connected to a remotely located relative to the Behälteraufiiahme region of the feed member, that at a distance from the front end of the feed member can be arranged on the feed member. In this case, the feed member is moved on movement of the feed member on the Behälteraufiiahme to first in the Behälteraufiiahme before the retaining member is released from the advancing member. Here, the advancing member z. B. acted on the stopper in the container, such as for mixing components or for a priming operation, and only then the holding member is released from the feed member.

It is also possible to provide a fastening device for the holding element at the inner region of the Behälteraufiiahme at which the retaining element is held as soon as the retaining element passes during the movement of the component, such as the feed member and the Behälteraufiiahme relative to one another in the region of the fastening means. The fastening means may be provided at a location within the Behälteraufiiahme provided by a defined distance to the edge of the container. The fastening device is preferably provided at a location within the Behälteraufiiahme, which adjoins the edge of a container, so that the retaining element comes to rest the edge of the container with respect to when it is held by the fastening device. It is only necessary to ensure that the fastener is not covered by the vessel. Provided that the attachment device does not join at the edge of the container, so that the edge can assist in releasing the retaining element from the component, the securing device holds the holding element firmly in such a way that will overcome the retaining force between the retaining element and the component and the support member solely by the adherence to the fastening device is disengaged from the component. In this case, the holding member can be placed in the Behälteraufiiahme with a predetermined distance from the edge of the container.

The attachment means may be provided on the Behälteraufhahme for example, by a fastening means on the holding element and a complementarily designed mating fastener, wherein the fastening means and the counter fastening means can engage in such a way that the holding element is secured in the axial direction in the Behälteraufhahme. The fastening means and the counter fastening means can be provided which can engage with each other, for example by detent means and counter-detent means. Preferably, the fastening means and the counter-fastening means are formed as externally and internally threaded. On the inner periphery of the Behälteraufhahme a revolving internal thread is provided, for example, while an external thread is provided on the outer circumference of the holding element. The thread ridges are formed so flexible that they initially above the other engage in an axial movement of the component, such as a feed member, and the Behälteraufhahme in the axial direction before the retaining element of the component dissolves, wherein the internal thread comes to lie in the outer thread. In order to ensure a sufficient radial flexibility of the threads to one another, the external thread may be divided into thread segments on the holding element. There are at least two thread segments provided on opposite sides of the retaining element, but it may also be three, four or five thread segments are provided.

In an alternative embodiment, the holding element can, for. B. be provided as a metal ring which has obliquely outwards projecting detent prongs at the circumference. The retainer ring can be applied to the component such. B. the feed member, to be placed at the end facing the Behälteraufhahme or within a certain distance from this end. The retaining ring can be retained in a groove on the component in a predetermined position. Upon insertion of the Behälteraufhahme in the housing, the component is introduced into the interior of the Behälteraufhahme, wherein the locking prongs can slide along the inner periphery of Behälteraufhahme. The latching prongs are formed obliquely outwards counter to the insertion projecting on the retaining ring. As soon as the device is moved relative to Behälteraufhahme opposite to the insertion, the latching tines engage the peripheral wall of the Behälteraufhahme. this may additionally ribs or grooves on the peripheral wall be provided. But the catch spikes can hook directly into the inner circumferential wall, for. B. if this is made of plastic. The holding element is thus mounted in the first position on the outer circumference of the component, such as some of the feed member and fixed in a second position on an inner periphery of the Behälteraumahrne.

In a preferred embodiment of a delivery device with a holding element according to the present invention, the fastening means between the retaining element and the container vessel is described as above by an inner and an outer thread formed. The holding member is a at least partly radially extending stop edge is provided at least at least interacts in the circumferential direction with an axially extending stop rib on the component, such as the feed member. The stop ribs on the component possibility to front on, the container end facing, or be provided in a spaced apart to this end area on the component. In the first position the retaining element is arranged on the component. The Behälteraumahme is introduced by means of a threaded connection between the outer circumference of the container receptacle and the housing inner periphery by means of a rotational movement axially into the housing. The tank holder is moved towards the component. As soon as the male thread segments are engaged in the internal thread of Behälteraumahme on the holding element, the holding element is held in the threaded engagement, while the container receptacle is further moved across the component. Thereby, a force in the axial direction of the holding member is exerted relative to the component which is sufficient to release the connection between the retaining element and the component, that is, the carrier device carrying the holding element on the component to be solved. By a continuous further rotation of the container relative to the housing receiving the retaining element will be twisted together with the container receptacle relative to the component. The retaining member is long as rotated together with the container receptacle until the stop edge abuts against the stop rib on the component on the holding element. If the Behälteraumahme further rotated, the holding member is prevented by the stops from rotating, and is thus rotated relative to the Behälteraumahme, wherein the external thread segments of the holding member are rotated within the internal thread of the container receptacle and the holding element to move axially in the direction of the edge of the container, until it is stopped at this. The holding member thus forms a sort of lock nut that can be tightened by the rotation of the B ehälter micrograph relative to the component by means of the stop edge and the stopper ribs. In this position, the retaining element is in the second position and forms a stop against an axial movement of the container within the container receptacle, the container through the axial component during the rotation of the retaining element against the locking shoulder in the Behälteraufhahme is pressed.

In a particularly preferred embodiment, the component is provided as the feed member and the holding member is integrally formed thereon. Such a feed member with integrated holding member can be produced for example by an injection molding process. The retaining element is attached by means of predetermined breaking points on the feed member which form the carrier device. If the feed member inserted into the Behälteraufhahme break the predetermined breaking points when the retaining member is fixed by the fixing device on the container receptacle. After the breaking of the predetermined breaking points of the fracture area preferably forms the radially inwardly projecting stop edges on the retaining element, which cooperate with the stop ribs on the feed member. Depending on the position of the stop ribs on advancing member, it is possible that the holding element is tightened before the feed member hits the stopper in the container or after the plug has been moved from the feed member such. For example, for mixing of components in a two-compartment carpule, or for a priming operation.

In an alternative embodiment of a delivery device with a holding element according to the present invention, the fastening means between the holding member and the Behälteraufhahme at a predetermined distance from the edge of the container is provided. In this case, the container with play between the locking shoulder of the Behälteraufhahme and the retaining element at the Behälteraufhahme remains movable axially by this distance. When attaching an injection needle unit on the receiving area of ​​the Behälteraufhahme can then z. For example, the cannula of the needle unit towards the container, such. B. butt against the septum, and push away the container within the Behälteraufhahme from the receiving area, or from the stopper recess. Accordingly, the septum is not pierced when placing the injection needle unit. However, once the feed member acts on the stopper in the container at a feed motion, the container is moved relative to the Behälteraufhahme and injection needle unit, whereby the needle is pricked through the septum first, then abuts the container at the stopper recess and ultimately the product from the container through the cannula is administered.

BRIEF DESCRIPTION OF THE DRAWINGS

Preferred embodiments of the invention are described below with reference to the drawings, which are illustrative only and are not to be interpreted as limiting. From the drawings Features disclosed by the invention should be considered separately and in any combination belonging to the disclosure of the invention. In the drawings represent:

Fig. 1: longitudinal section through a distal portion of a first embodiment of an administering device according to the present invention in a first position,

Fig. 2: three-dimensional view of a feed member with a

Retaining element,

Fig 3 a. Detail view of a first circumferential region of the delivery device of Figure 1;

FIG. 3b: Detailed view of a second circumferential region of the delivery device of Figure 1;

FIG. 4 shows a longitudinal section through a distal portion of a delivery device of Figure 1 in an intermediate position,

FIG. 5a: detail view of a first circumferential region of the delivery device of Figure 4,

Fig. 5b: detailed view of a second circumferential portion of a

The delivery device of Figure 4,

FIG. 6 shows a longitudinal section through a distal portion of the delivery device of Figure 1 in a second position, Fig. 7: detailed view of a delivery device of Figure 6,

Fig. 8: longitudinal section through a first delivery device according to the

Embodiment in a third position,

Fig. 9: Three-dimensional representation of a feed member with a

Support member according to a second Ausföhrungsform of the present invention,

Fig. 10: longitudinal section through a distal portion of a delivery device according to the second embodiment, and

Fig. 11: Detail view of the delivery device of Figure 10.

In the following, the end is at a distal end of a delivery device meant to be mounted on which a needle unit and on which is carried a distribution of a product. The proximal end is the opposite end to the distal end of the delivery device, usually the operation of the delivery device occurs at the.

1 shows a first embodiment of an administering device in accordance with the present invention in a first position corresponding to the starting position of the device. In Figure 1, the distal region of the delivery device is shown, while the delivery device is shown as a whole in Figure 8, where, however, in a third position.

As can be seen in Figure 1, the delivery device comprises a housing 1, a container receptacle 2 and a container accommodated in the Behälteraumahme 3. The housing 1 has an inner thread 4, which cooperates with an external thread 5 on the outer circumference of the Behälteraumahme. 2 The housing 1 and the Behälteraumahme 2 are thus cylindrical and can by means of the internal thread 4 and said external thread 5 is screwed into one another, wherein the Behälteraufhahme 2 moves axially in the housing 1 into it. The container 3 is formed as a two-chamber carpule which has a first chamber 6 having a first component and a second chamber 7 with a second component. The first chamber 6 is provided between a head 8 of the container having a sealed with a septum opening, and a first stopper. 9 The second chamber 7 is arranged between the first plug and a second plug 9 10th In the peripheral wall of the cartridge 3, a bypass is provided which serves for the transfer of a component from the second chamber into the first chamber 23rd For redirecting the second component of the second plug 10 is advanced within the cartridge in the direction of the vessel head 8, the force being transmitted through the located in the second chamber component on the first plug 9, so that this in the direction of the head 8 and in the region of the bypass is moved. By further advancing the second plug 10, the component is transferred from the second chamber 7 via the bypass 23 in the first chamber 6, so that the two components form a blended product.

The head 8 is received in a tapered receiving portion 11 within the Behälteraufhahme. 2 an injection needle unit can be fitted in such a manner over the receiving area 11 such that an injection needle passes through an opening of the receiving area, through the septum and the opening of the container in the interior of the first chamber 6 of the cartridge, thus establishing fluid communication. the mixed product is administered by the injection needle from the container 3 by further advancing the plug 9 and 10. FIG.

In this embodiment, a delivery device, the container 3 is pushed into the container receptacle 2, to a shoulder 12 of the container abuts an inwardly into the container receptacle stop edge 13 in the direction of insertion. The stop edge 13 will be provided by a tapered portion of the container between the receiving area 11 for the head and a sleeve portion of the Behälteraufhahme, which serves to receive the container body. Once the container is inserted into the Behälteraufhahme 2 3, the Behälteraufhahme 2 can be screwed into the housing 1 via a first short distance into the housing 1, as shown in the initial state in FIG. 1

The delivery device comprises a delivery mechanism (see Figure 8) comprising a feed member 14 which is provided for advancing the plug 9 and 10. FIG. The feed member is a member to which the container receptacle is moved axially 2 when the container receptacle is screwed into the housing 1 2, and which serves as a support member for the holding element.

At the feed member 14 a holding element 15 is arranged. The holding member 15 is located at a distal end of the feed link and is removably attached thereto. The feed member 14 serves as a support member for supporting the holding member 15 in the initial position. In the initial position of figure 1, the actuating member 2 is located relative to the feed member 14 in a first displacement position, in which the holding element 15 is arranged on the feed member fourteenth In this first shift position between container receiving and advancing member, the retaining element 15 is spaced from the proximal edge 16 of the container. 3 Furthermore, the holding element is arranged in front of a hmenumfang formed on the container receptacle 2 internal thread 17 and is thus located on a proximal side of the internal thread.

2 shows a three-dimensional representation of the feed member 14 and the retaining element 15 is shown. The holding member 15 is ring-shaped and has three male thread segments 18 which are arranged symmetrically on the outer circumference of the annular retaining element 15 °. Between the external thread segments 18 15 three flat peripheral segments 19 are provided on the circumference of the holding element. The external thread segments 18 protrude in the radial direction over the flat peripheral segments 19 and together form an outer thread on the support member 15. The external thread segments 18 of the holding member 15 can with the internal thread 17 of the B 2 ehälter micrograph cooperate. They form a self-locking thread with this. The holding element is preferably made of such material, as plastic, that the ring is flexible and can be compressed somewhat.

The holding member 15 is attached by a plurality of ridges 20 on the front side of the feed member fourteenth Here, the holding member 15 protrudes from the front edge of the feed element 14th The webs 20 form can break 14 14 break points, for example, by a slight axial pressure in the direction of the feed member at its transition to the feed member. The predetermined breaking points are provided by inwardly towards the feed member 14 protruding edges 21st The edges 21 constitute a carrier means with which the retaining member is carried by the feed member fourteenth

The feed member 14 has at its distal end on its outer circumference axially extending ribs 22nd The ribs 22 are slightly projecting from the outer circumference of the feed member fourteenth Preferably, many ribs are also provided 22 as webs 20 and edge 21 are provided on the holding element 15 °.

In Figures 3 a and 3b show two detailed sections of the circumference of the delivery device shown in the region of the holding element. In Figure 3, a housing 1 is shown, in which the container receptacle 2 is inserted. Within the Behälteraufhahme 2, the retaining element 15 is located in the starting position before the internal thread 17 of the container receptacle. 2 An external thread segment 18 of the holding member 15 comes to lie against an inner peripheral surface of the container receptacle. 2 In figure 3b is the opposing area, so a shown by 180 degrees compared to the area of ​​Figure 3a offset area. The holding member 15 is attached by means of a web 20 and an edge 21 on the feed member fourteenth The web 20 is located at a peripheral flat segment 19 of the holding element 15, which is opposed to the inner periphery of the Behälteraufhahme. 2 From the figures 3 a and 3b it can be seen that 18 and arranged on an opposite, offset by 180 degrees side a flat peripheral segment 19 is provided along the diameter of the retaining element 15 on one side an outer thread segment.

In Figure 4, the administration device is shown according to the first embodiment of the present invention in a second intermediate position. From the initial position to the intermediate position the Behälteraufhahme 2 has been moved further into the housing 1 by being screwed by means of the internal thread 4 and external screw thread 5 into the housing. By inserting the Behälteraufhahme 2 in the housing 1, the Behälteraufhahme 2 moves axially on the feed member 14 to the retaining element 15 °. Due to the relative displacement between the Behälteraufiiahme 2 and the feed member 14 and the holding member 15 is moved axially in the direction of the container 3 inside the Behälteraufiiahme 2, until it engages in the internal thread 17th It may abut on the margin 16 of the container. The segments 18 having the external thread can easily be pressed inward so that the outer thread of the segments 18 is pushed over the internal thread 17 of the Behälteraufiiahme. 2 The flat peripheral segments 19 of the holding element 15 can thereby be bent flexibly outward. The internal thread 17 of the Behälteraufiiahme 2 and the external thread segments 18 of the retaining element 15 can thus form a mounting means for mounting the holding element 15 on the Behälteraufiiahme. 2

In the figures 5a and 5b, the area of ​​the delivery device with the holding element 15 in two opposite cut-outs shown. In Figure 5a, the retaining element 15 abuts the rim 16 of the container. 3 The external thread segment 18 is engaged in the internal thread 17 of the container receptacle 2, or snapped. From Figure 5a it can be seen that the external thread segments 18 are not connected to the feed member 14 and can avoid flexible radially inwardly thus, as soon as they are moved in the feed direction via the internal thread 17th In Figure 5b, an opposite segment of the holding element 15 is shown. The retaining element 15 abuts with its distal end to the edge 16 of the container 3 and is attached to the feed member 14 by means of the web 20 and the edge of the 21st The web 20 is located at a peripheral flat segment 19 of the holding member 15 and is spaced from the internal threads 17 of the container receptacles. 2

hi Fig. 6 is the first embodiment of the delivery device of the present invention in a second position, the stop position shown. Opposite the intermediate position, the Behälteraufiiahme 2 was further inserted into the housing 1, thus further member via the feed 14 is moved so that it is located in a second displacement position. In this case, the holding member 15 is released from the feed member fourteenth During the movement of the container receptacle 2 via the feed member 14, the feed member is moved into the container 3 fourteenth The retaining element 15 is, however, engaged in the internal thread 17 or pushes even at the edge 16 of the container 3 and thus can not be moved further in the direction of the container. Due to the axial thrust, the predetermined breaking points to the webs 20 so that the retaining element is separated from the feed member 14 15 break. The holding member 15 is arranged in the holding position in the Behälteraufhahme 2 and forms a retaining stop for the container. The container can thus no longer be moved in the proximal direction along the Behälteraufhahme. In the distal direction of the container with the shoulder 12 against the stop edge 13 of the Behälteraufhahme 2 present. The container 3 is thus held in both axial directions within the Behälteraufhahme. 2

7 shows a detail view of the delivery device is shown in a holding position in accordance with FIG. 6 The holding member 15 is released from the feed element 14 and is supplied with the external thread segments 18 within the internal thread 17 of the B 2 ehälter micrograph maintained. The holding member 15 is in the axial direction at the edge 16 of the container. 3 The feed member 14 has been moved relative to Behälteraufhahme 2 and the container 3 in the distal direction on the stopper 10 to.

In the holding position of the holding member 15, the predetermined breaking points at the edges 21 of the webs 20 of the retaining element 15 are broken and the edges 21 project radially inwardly towards the feed member 14. The retaining member 15 is in the holding position with its external thread segments 18 in the internal thread 17 of the Behälteraufhahme stored for 2 and is rotated together with the Behälteraufhahme 2 at a further screwing the Behälteraufhahme 2 in the housing 1 relative to the feed member fourteenth The feed member 14 is axially displaceable in the housing 1, but non-rotatably mounted. By the relative rotation between the Behälteraufhahme 2 with the retaining element 15 relative to the feed member 14 and the holding member 15 is membered compared with the feed 14 twisted, to which abut inwardly projecting edges 21 of the holding member 15 to the ribs 22 on the outer circumference of the feed member fourteenth The ribs 22 thus form a stop for the holding element 15 in the direction of rotation. If the Behälteraufhahme 2 further screwed into the housing 1 while continuing rotated relative to the feed member 14, the retaining element will be prevented from 15 by the abutment of the edges 21 on the ribs 22 at a rotating with the container receptacle 2 and is instead rotated relative to the Behälteraufhahme 2 , Due to the threaded engagement of the external thread segments 18 of the holding member 15 with the inner thread 17 of the Behälteraufhahme 2 the retaining member 15 is rotated within the threaded connection. By this rotational movement, the holding element is due to the threaded connection axially in the distal direction, ie in the direction of the container 3 is shifted.

Once the retaining element 15 determines is present at the edge 16 of the container, the webs slip 20 of the holding member 15 via the ribs 22 of the feed member 14. Thereby, the Behälteraufhahme 2 further be screwed into the housing 1, without the holding member 15 also in the threaded connection 17 , 18, is twisted. The retaining member 15 now holds the container 3 securely in the Behälteraufhahme. Such tightening of the retaining element 15 within the thread 17 is especially advantageous if the predetermined breaking points to the webs 20 15 already in the imports of the holding member 15 in the threaded portion of the female thread break, the retaining element 17 of the Behälteraufhahme 2, but the support member 15 is not at the edge 16 of the container 3 abuts.

8 shows a longitudinal section of an administering device according to the first embodiment is shown with a delivery mechanism in the proximal region of the housing. In Figure 8, the administration device in a third position, the mixing position shown in which the Behälteraufhahme 2 is further screwed into the housing. 1 In this case, the container 3 is pushed to the stopper 10 via the feed member 14, so that the stoppers are moved 9 and 10 within the container. 3 Once the first plug 9 comes to lie in the region of the bypass 23, the second component from the second chamber 7 flows through the bypass 23 in the first chamber 6, wherein the second plug 10 is moved further inside the container 3 in the distal direction until it connecting to the first plug. 9 The component in the first chamber 6 and the component from the second chamber 7 now form a fluid product which may be administered by replacement of a needle unit on the receiving area 11 of the Behälteraufhahme. 2 For administration of the fluid product from the chamber 6 of the dispensing mechanism of the delivery device is actuated.

The administration mechanism comprises among others the feed member 14 and a release button 24, which is located at the proximal end of the Verabreichungsvoπichtung. The feed member 14 is formed like a sleeve and receives a drive spring 25 in to. At the proximal end, the feed member 14 has two retaining hooks 26, with which the feed member 14 is held against the bias of the spring 25 relative to the housing. By the actuation of the release button 24, the retaining hook 26 can be detached from its holder and the drive spring exerts a drive force 25 on the feed member 14 in the direction of the plug 9, or 10. The feed member 14 is thus displaced relative to the housing 1 and pushes the stopper inside the container 3 is present, whereby the fluid product from the first chamber 6 may be distributed.

In Figures 9 to 11 show a second embodiment of an administering device in accordance with the present invention. Figure 9 shows a three dimensional view of a feed member 30, at the end of a stop element is arranged 31st The retaining element is designed as a metal ring extending from the outer periphery thereof four retaining prongs 32nd The retaining ring 31 may come to rest in a circumferential groove on the feed member 30, from which it is releasable by pressure in the axial direction. For this purpose, the retaining ring may have formed also on the inner periphery projections, which engage in the groove. The holding prongs 32 project obliquely to the longitudinal axis of the feed member 30 to the outside of the retaining ring. In this case 32, the retaining spikes in the proximal direction. In the illustrated embodiment, a holding member 31, four retainer tines 32 are shown. It can, however, only two or three stops pips or more than four retention tines be provided.

10 shows a longitudinal section of the proximal portion of the second embodiment of an inventive delivery device is shown. Components of the delivery device that match with the first embodiment according to Figures 1 to 8 are designated by like reference numerals. In Figure 10, the Behälteraufhahme 2 with the container 3 is screwed by means of the internal thread 4 and external screw thread 5 in the housing into the housing. 1 The Behälteraufhahme 2 is moved so far into the housing 1 into and through the feed member 30, the retaining ring 31 abuts the edge 16 of the container. 3 The delivery device is in this position in the holding position. As can be seen in Figure 11, the retaining prongs 32 of the retaining ring 31 are engaged with the inner peripheral surface of Behälteraufhahrne 2 in the holding position. The Behälteraufhahme 2 is preferably made of plastic, so that the metal tines can edging in the circumferential surface, since the plastic material is softer than the metal. The holding prongs protrude obliquely in the proximal direction, so that the outer peripheral surface of the container receptacle 2 can slide along the retaining prongs 32 during insertion of the feed member 14 in the Behälteraufhahme 2 without this tilt. In a movement counter to the insertion direction of the feed member 30 into the container receptacle 2, however, the inner peripheral surface of Behälteraufhahme is moved toward the tips of the retainer tines 32, so that this tilt in the circumferential wall.

In Figure 11, the retaining ring 31 abuts the rim 16 of the container. 3 The retaining ring 31 can not be further moved in the Behälteraufhahme 2 together with the feed member, but it is released by the stop on the edge 16 of the feed member 30 and fixed by the tilting of the holding prong 32 at the Behälteraufhahme. 2 The container 3 is held by the retaining ring 31 securely in the container vessel as it pushes in one direction with its shoulder 12 against the stop edge 13 of the receiving area 11 of the Behälteraufhahme 2 and pushes in the opposite direction against the retaining ring 31 when a force tilted in this direction in the peripheral wall. The feed member 30 may be moved inside of the retaining ring 31 in the axial direction, since the retaining ring 31 is held by the tilting securely on the container receptacle. 2

The present invention has been exemplified with reference to two embodiments. However, other variants of a holding element are also conceivable, as long as such a retaining member is disposed in an initial position to a structural member of the delivery device and is dissolved in a holding position of the latter and is connected to the Behälteraufhahme such that it comprises a retaining stop for the container in the Behälteraufhahme forms. In principle it is also possible to provide a different component of the delivery device as the feed member as the support for the retaining element, as long as such a carrier can be moved in the axial direction of the Behälteraufhahme. The Behälteraufhahme can be moved relative to the carrier and the housing, as is the case with the embodiments shown, or it may be the carrier to be moved relative to the housing and the Behälteraufhahme.

LIST OF REFERENCE NUMBERS

1 case

2 Behälteraufiiahme

3 container

4 female

5 male thread

6 first chamber

7 second chamber

8 head

9, first plug

10, the second stopper

11 receiving area

12 shoulder

13 stop edge

14 advancing member / support member

15 holding element

16 container edge

17 female thread

18 external thread segment

19 flat circumferential segment

20 web

21 edge

22 rib

23 bypass

24 release button

25 drive spring

26 retaining hook

30 advancing member

31 holding element

32 holding spikes

Claims

1. delivery device for administering a fluid product, comprising: disposed a housing (1) into the housing (1) mounted component (14) and one in or on the housing (1) container receptacle (2), in which a
Container (3) is accommodated with the fluid product, wherein the component (14) and the Behälteraufhahme (2) are axially movable towards each other, characterized in that a retaining element (15; 31) is provided which in a first position of the container receptacle (2) relative to the component is arranged (14) releasably attached to the component (14) and in a second position in which
Container receptacle (2) is moved in the direction of the component (14) from which
Component is dissolved and the container receptacle (2) is mounted such that it forms a retaining stop for the container (3) in the container receptacle (2).
2. of administration device according to claim 1, characterized in that the container receptacle (2) is axially movable relative to the housing (1) from the first position to the second position.
3. The delivery device of any of the preceding claims, characterized in that the container receptacle (2) has an external thread (5), cooperates with an internal thread (4) on the housing (1).
4. The delivery device of any of the preceding claims, characterized in that the Behälteraufhahme (2) over the component (14) is movable, wherein the component (14) at least partially accommodates in itself.
5. The delivery device of any of the preceding claims, characterized in that the holding element (15; 31) is annular.
6. The delivery device of any of the preceding claims, characterized in that the holding element (15; 31) is mounted in the first position on the outer circumference of the component (14).
7. The delivery device of any of the preceding claims, characterized in that the component (14) is formed as a support member having a support device (21), said carrier device holds the holding element (15) in the first position on the component and in the second position the holding member (15) releases it.
8. The delivery device of any of the preceding claims, characterized in that the holding element (15; 31) in the second position on an inner periphery of the B micrograph ehälter is attached (2).
9. The delivery device of any of the preceding claims, characterized in that the holding element (15; 31) is releasable by a stop (16) within the Behälteraufhahme (2) from the component (14) when the Behälteraufhahrne (2) in the direction of the component is moved (14).
10. The delivery device of any of the preceding claims, characterized in that the holding element (15; 31) in the second position forms a stop that blocks axial movement of the container (3) relative to the Behälteraufhahme (2) in one direction and a stopper recess (13) on the Behälteraufhahme (2) is provided that blocks axial movement of the container (3) relative to the Behälteraufhahme (2) in an opposite direction.
which engages in said second position in a counter-fastening means (17) on the Behälteraufhahrne (2); 11. The delivery device of any of the preceding claims, characterized in that the holding element (15) a fastening means (32 18).
12. The delivery device of claim 11, characterized in that the fastening means (18; 32) and the counter fastening means (19) as latching means, and counter-locking means are formed, which are latched to one another.
13. The delivery device of claim 11, characterized in that the attachment means or the counter-fastening means as an external thread (18) or internal thread (17) are formed.
14 of administration device according to the preceding claim, characterized in that the external thread at at least two circumferential segments (18) of the holding element (15) is formed.
15. The delivery device of any of claims 13 or 14, characterized in that the external and internal threads (17, 18) form a self-locking thread.
16 of administration device according to one of the preceding claims, characterized in that the holding element (15) has at least one stop edge (21) which interacts in the circumferential direction with at least one axially extending stop rib (22) on the component (14).
17. The delivery device of any of the preceding claims, characterized in that the component of a feed member (14) is formed, which is mounted for administering the fluid product from the container (3) relative to the container (3) displaceable in the housing (1) ,
PCT/CH2009/000035 2009-01-30 2009-01-30 Administering device comprising a holding element for a fluid receptacle WO2010085903A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CH2009/000035 WO2010085903A1 (en) 2009-01-30 2009-01-30 Administering device comprising a holding element for a fluid receptacle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH2009/000035 WO2010085903A1 (en) 2009-01-30 2009-01-30 Administering device comprising a holding element for a fluid receptacle

Publications (1)

Publication Number Publication Date
WO2010085903A1 true WO2010085903A1 (en) 2010-08-05

Family

ID=41225995

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH2009/000035 WO2010085903A1 (en) 2009-01-30 2009-01-30 Administering device comprising a holding element for a fluid receptacle

Country Status (1)

Country Link
WO (1) WO2010085903A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8591463B1 (en) 2013-03-08 2013-11-26 Teva Pharmaceutical Industries Ltd. Re-useable injector device for syringe
US8652100B1 (en) 2013-03-08 2014-02-18 Teva Pharmaceutical Industries, Ltd. Re-useable injector device for syringe
WO2014056874A1 (en) * 2012-10-12 2014-04-17 Carebay Europe Ltd Medicament delivery device
USD745664S1 (en) 2013-11-25 2015-12-15 Teva Pharmaceutical Industries, Ltd. Injector device for a syringe
WO2016193313A1 (en) * 2015-06-02 2016-12-08 Biocorp Production Method for producing at least one reservoir assembly, injectable-product reservoir assembly for an injection pen and injection pen equipped with such an assembly

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2228585A (en) * 1939-03-22 1941-01-14 Delmer I Pletcher Thrust head for syringes
US4333456A (en) * 1981-02-09 1982-06-08 Sterling Drug Inc. Self-aspirating hypodermic syringe and self-aspirating assembly therefor
EP0341612A1 (en) * 1988-05-13 1989-11-15 L. MOLTENI & C. DEI F.LLI ALITTI S.P.A Anticontagion device for injecting dental anesthetic solutions contained in cartridges
US5405326A (en) * 1993-08-26 1995-04-11 Habley Medical Technology Corporation Disposable safety syringe with retractable shuttle for luer lock needle
EP0829268A2 (en) * 1996-09-17 1998-03-18 Becton Dickinson and Company Non-floatable insulin cartridge holder for medication delivery pen
DE102007016811A1 (en) * 2007-04-05 2008-10-09 Tecpharma Licensing Ag A device for administering a fluid drug from a multi-chamber ampoule

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2228585A (en) * 1939-03-22 1941-01-14 Delmer I Pletcher Thrust head for syringes
US4333456A (en) * 1981-02-09 1982-06-08 Sterling Drug Inc. Self-aspirating hypodermic syringe and self-aspirating assembly therefor
EP0341612A1 (en) * 1988-05-13 1989-11-15 L. MOLTENI & C. DEI F.LLI ALITTI S.P.A Anticontagion device for injecting dental anesthetic solutions contained in cartridges
US5405326A (en) * 1993-08-26 1995-04-11 Habley Medical Technology Corporation Disposable safety syringe with retractable shuttle for luer lock needle
EP0829268A2 (en) * 1996-09-17 1998-03-18 Becton Dickinson and Company Non-floatable insulin cartridge holder for medication delivery pen
DE102007016811A1 (en) * 2007-04-05 2008-10-09 Tecpharma Licensing Ag A device for administering a fluid drug from a multi-chamber ampoule

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI566798B (en) * 2012-10-12 2017-01-21 Carebay Europe Ltd Medicament delivery device
WO2014056874A1 (en) * 2012-10-12 2014-04-17 Carebay Europe Ltd Medicament delivery device
CN104780958A (en) * 2012-10-12 2015-07-15 卡贝欧洲有限公司 The medication delivery device
US9833578B2 (en) 2012-10-12 2017-12-05 Carebay Europe Ltd Medicament delivery device
US8591463B1 (en) 2013-03-08 2013-11-26 Teva Pharmaceutical Industries Ltd. Re-useable injector device for syringe
US10071206B2 (en) 2013-03-08 2018-09-11 Teva Pharmaceutical Industries Limited Re-useable injector device for syringe
US8652100B1 (en) 2013-03-08 2014-02-18 Teva Pharmaceutical Industries, Ltd. Re-useable injector device for syringe
US9827374B2 (en) 2013-03-08 2017-11-28 Teva Pharmaceutical Industries Limited Re-useable injector device for syringe
USD745664S1 (en) 2013-11-25 2015-12-15 Teva Pharmaceutical Industries, Ltd. Injector device for a syringe
WO2016193313A1 (en) * 2015-06-02 2016-12-08 Biocorp Production Method for producing at least one reservoir assembly, injectable-product reservoir assembly for an injection pen and injection pen equipped with such an assembly
FR3036969A1 (en) * 2015-06-02 2016-12-09 Biocorp Prod Method for manufacturing at least one reservoir assembly, reservoir assembly of injectable product to a pen injector pen injector crew of such an assembly

Similar Documents

Publication Publication Date Title
CA2156696C (en) Cartridge retainer assembly for medication delivery pen
CA2151832C (en) Improvements in injection devices
JP5854836B2 (en) Cartridge and needle system for the
EP1094857B1 (en) A medical delivery device and a cartridge assembly for use in the same
US8343103B2 (en) Injection device with tensioning spring and tensioning element
CA2209956C (en) Cannula sealing shield assembly
CA2387893C (en) Medical injector and medicament loading system for use therewith
US4820286A (en) Automatic injector
AU2008271920B2 (en) Prefilled retractable syringe, plunger and needle assembly therefor
US7771399B2 (en) Injection device with dose metering mechanism with multiple anti-rotation locking system
US4568346A (en) Hypodermic syringe having a telescopic assembly between cartridge and medicament holder
US4643721A (en) Multiple compartment ampule for automatic hypodermic syringes
AU2004298302B2 (en) Releasable injection device
CA2451889C (en) Reservoir module with a piston rod
EP0562671B1 (en) Automatic injector
US6981963B2 (en) Pre-filled safety diluent injector
AU733120B2 (en) Preloadable syringe for automated dispensing device
RU2270034C2 (en) Body section connection of injection apparatus for dosed injection of supplied substance
US20030212380A1 (en) Passive safety shield system for injection devices
EP0990446B1 (en) Pen needle magazine
US8617124B2 (en) Medicament delivery device
EP0937474B1 (en) Vial retainer interface to a medication delivery pen
US4957490A (en) Injection device
US20180085531A1 (en) Two-Stage Reconstituting Injector
US20020183690A1 (en) Syringe for automatic injection of an extemporaneous mixture

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09775704

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09775704

Country of ref document: EP

Kind code of ref document: A1