WO2010080582A3 - Molecular assay for diagnosis of hiv tropism - Google Patents

Molecular assay for diagnosis of hiv tropism Download PDF

Info

Publication number
WO2010080582A3
WO2010080582A3 PCT/US2009/068665 US2009068665W WO2010080582A3 WO 2010080582 A3 WO2010080582 A3 WO 2010080582A3 US 2009068665 W US2009068665 W US 2009068665W WO 2010080582 A3 WO2010080582 A3 WO 2010080582A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnosis
molecular assay
hiv tropism
hiv
amplified
Prior art date
Application number
PCT/US2009/068665
Other languages
French (fr)
Other versions
WO2010080582A2 (en
Inventor
Thomas G Laffler
Mark A Hayden
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Priority to CA2746098A priority Critical patent/CA2746098A1/en
Priority to AU2009335688A priority patent/AU2009335688B2/en
Priority to RU2011129765/10A priority patent/RU2011129765A/en
Priority to EP09796219A priority patent/EP2376651A2/en
Priority to JP2011542468A priority patent/JP2012512663A/en
Priority to US13/140,271 priority patent/US20110262924A1/en
Publication of WO2010080582A2 publication Critical patent/WO2010080582A2/en
Publication of WO2010080582A3 publication Critical patent/WO2010080582A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Abstract

The invention is directed to compositions, methods and kits for HIV subtypes in a test sample, wherein target sequence are amplified. The amplified target sequences are then analyzed by any number of mass spectrometric techniques, which data are queried against a database of base composition signatures of HIV subtypes.
PCT/US2009/068665 2008-12-19 2009-12-18 Molecular assay for diagnosis of hiv tropism WO2010080582A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA2746098A CA2746098A1 (en) 2008-12-19 2009-12-18 Molecular assay for diagnosis of hiv tropism
AU2009335688A AU2009335688B2 (en) 2008-12-19 2009-12-18 Molecular assay for diagnosis of HIV tropism
RU2011129765/10A RU2011129765A (en) 2008-12-19 2009-12-18 MOLECULAR TEST USED FOR DIAGNOSTIC OF HIV TROPISM
EP09796219A EP2376651A2 (en) 2008-12-19 2009-12-18 Molecular assay for diagnosis of hiv tropism
JP2011542468A JP2012512663A (en) 2008-12-19 2009-12-18 Molecular assay for diagnosing HIV tropism
US13/140,271 US20110262924A1 (en) 2008-12-19 2009-12-18 Molecular assay for diagnosis of hiv tropism

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13941808P 2008-12-19 2008-12-19
US61/139,418 2008-12-19

Publications (2)

Publication Number Publication Date
WO2010080582A2 WO2010080582A2 (en) 2010-07-15
WO2010080582A3 true WO2010080582A3 (en) 2010-10-07

Family

ID=42075362

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/068665 WO2010080582A2 (en) 2008-12-19 2009-12-18 Molecular assay for diagnosis of hiv tropism

Country Status (7)

Country Link
US (1) US20110262924A1 (en)
EP (1) EP2376651A2 (en)
JP (1) JP2012512663A (en)
AU (1) AU2009335688B2 (en)
CA (1) CA2746098A1 (en)
RU (1) RU2011129765A (en)
WO (1) WO2010080582A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013032223A2 (en) * 2011-06-15 2016-12-20 Grifols Therapeutics Inc isolated nucleic acid molecule and composition
CA2838091C (en) * 2011-07-05 2019-08-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Hiv-1 genotyping assay for global surveillance of hiv-1 drug resistance
JP6461804B2 (en) * 2012-10-18 2019-01-30 ザ ロックフェラー ユニバーシティー Broad neutralizing anti-HIV antibody

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992008808A1 (en) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor
EP1193313A1 (en) * 1999-06-15 2002-04-03 Otsuka Pharmaceutical Co., Ltd. Method for determining hiv-1 subtype
US20060194227A1 (en) * 2000-09-26 2006-08-31 Sean Philpott Heteroduplex tracking assay
US20080020370A1 (en) * 2000-09-26 2008-01-24 Sean Philpott Heteroduplex tracking assay

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8505174D0 (en) * 1985-02-28 1985-04-03 Versatile Eng Ltd Engraving tool holder
CA2600184A1 (en) * 2005-03-03 2006-09-08 Isis Pharmaceuticals, Inc. Compositions for use in identification of adventitious viruses

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992008808A1 (en) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor
EP1193313A1 (en) * 1999-06-15 2002-04-03 Otsuka Pharmaceutical Co., Ltd. Method for determining hiv-1 subtype
US20060194227A1 (en) * 2000-09-26 2006-08-31 Sean Philpott Heteroduplex tracking assay
US20080020370A1 (en) * 2000-09-26 2008-01-24 Sean Philpott Heteroduplex tracking assay

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ENGELBRECHT S ET AL: "Detection of southern African human immunodeficiency virus type 1 subtypes by polymerase chain reaction: Evaluation of different primer pairs and conditions", JOURNAL OF VIROLOGICAL METHODS, ELSEVIER BV, NL LNKD- DOI:10.1016/0166-0934(95)00088-7, vol. 55, no. 3, 1 January 1995 (1995-01-01), pages 391 - 400, XP002297330, ISSN: 0166-0934 *
GAO F ET AL: "Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID networks for HIV isolation and characterization", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 70, no. 3, 1 March 1996 (1996-03-01), pages 1651 - 1667, XP002123321, ISSN: 0022-538X *
JENSEN MARK A ET AL: "Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US LNKD- DOI:10.1128/JVI.77.24.13376-13388.2003, vol. 77, no. 24, 1 December 2003 (2003-12-01), pages 13376 - 13388, XP002433825, ISSN: 0022-538X *
KAKIZAWA J ET AL: "Diversity of HIV type 1 envelope V3 loop region in saliva.", AIDS RESEARCH AND HUMAN RETROVIRUSES 10 APR 1996 LNKD- PUBMED:8679313, vol. 12, no. 6, 10 April 1996 (1996-04-10), pages 561 - 563, XP002577171, ISSN: 0889-2229 *
NAGHAVI M H ET AL: "DNA sequence of the long terminal repeat of human immunodeficiency virus type 1 subtype A through G.", AIDS RESEARCH AND HUMAN RETROVIRUSES 20 MAR 1999 LNKD- PUBMED:10195759, vol. 15, no. 5, 20 March 1999 (1999-03-20), pages 485 - 488, XP002577172, ISSN: 0889-2229 *
PIENIAZEK D ET AL: "IDENTIFICATION OF MIXED HIV-1/HIV-2 INFECTIONS IN BRAZIL BY POLYMERASE CHAIN REACTION", AIDS, LONDON, GB, vol. 5, no. 11, 1 January 1991 (1991-01-01), pages 1293 - 1299, XP001006264, ISSN: 0269-9370 *
WILLEY ET AL: "Amino acid substitutions in the human immunodeficiency virus type 1 gp120 V3 loop that change viral tropism also alter physical and functional properties of the virion envelope", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 68, no. 7, 1 July 1994 (1994-07-01), pages 4409 - 4419, XP002119922, ISSN: 0022-538X *

Also Published As

Publication number Publication date
RU2011129765A (en) 2013-01-27
EP2376651A2 (en) 2011-10-19
WO2010080582A2 (en) 2010-07-15
AU2009335688A1 (en) 2011-07-07
US20110262924A1 (en) 2011-10-27
AU2009335688B2 (en) 2013-04-18
CA2746098A1 (en) 2010-07-15
JP2012512663A (en) 2012-06-07

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