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WO2010075860A3 - Barley with reduced lipoxygenase activity and beverage prepared therefrom - Google Patents

Barley with reduced lipoxygenase activity and beverage prepared therefrom

Info

Publication number
WO2010075860A3
WO2010075860A3 PCT/DK2009/050355 DK2009050355W WO2010075860A3 WO 2010075860 A3 WO2010075860 A3 WO 2010075860A3 DK 2009050355 W DK2009050355 W DK 2009050355W WO 2010075860 A3 WO2010075860 A3 WO 2010075860A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
lox
acid
barley
enzymes
lipoxygenase
Prior art date
Application number
PCT/DK2009/050355
Other languages
French (fr)
Other versions
WO2010075860A2 (en )
Inventor
Birgitte Skadhauge
Finn Lok
Klaus Breddam
Ole Olsen
Lene Mølskov Bech
Søren Knudsen
Original Assignee
Carlsberg Breweries A/S
Heineken Supply Chain B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Flowering plants, i.e. angiosperms
    • A01H5/10Seeds, e.g. gramineae leguminosae, brassicaceae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12CBREWING OF BEER
    • C12C1/00Preparation of malt
    • C12C1/18Preparation of malt extract or of special kinds of malt, e.g. caramel, black malt
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12CBREWING OF BEER
    • C12C12/00Processes specially adapted for making special kinds of beer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12CBREWING OF BEER
    • C12C2200/00Special features
    • C12C2200/01Use of specific genetic variants of barley or other sources of fermentable carbohydrates for beer brewing

Abstract

According to the invention, there is provided barley with total loss of functional lipoxygenase (LOX)-1 and LOX-2 enzymes, and plant products produced thereof, such as malt manufactured by using barley kernels defective in the synthesis of the fatty acid-dioxygenating enzymes LOX-1 and LOX-2. Said enzymes account for the principal activities related to dioxygenation of linoleic acid into 9- and 13-hydroperoxy octadecadienoic acid,respectively. 9-Hydroperoxy octadecadienoic acid represents a LOX pathway metabolite, which - through further enzymatic or spontaneous reactions - may lead to the appearance of trans-2-nonenal (T2N). The invention enables brewers to produce a beer having insignificant levels of stale,T2N-specific off-flavors, even after prolonged storage of the beverage.
PCT/DK2009/050355 2008-12-30 2009-12-28 Barley with reduced lipoxygenase activity and beverage prepared therefrom WO2010075860A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DKPA200801851 2008-12-30
DKPA200801851 2008-12-30

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13141579 US9363959B2 (en) 2008-12-30 2009-12-28 Barley with reduced lipoxygenase activity and beverage prepared therefrom
JP2011542680A JP5670347B2 (en) 2008-12-30 2009-12-28 Barley was reduced lipoxygenase activity and beverages prepared from their
CN 200980157631 CN102333440B (en) 2008-12-30 2009-12-28 Barley with reduced lipoxygenase activity
CA 2747225 CA2747225A1 (en) 2008-12-30 2009-12-28 Barley with reduced lipoxygenase activity
EP20090801148 EP2384110B1 (en) 2008-12-30 2009-12-28 Barley with reduced lipoxygenase activity and beverage prepared therefrom
US13701604 US9587210B2 (en) 2008-12-03 2011-05-31 Energy saving brewing method
US15413094 US20170183611A1 (en) 2008-12-03 2017-01-23 Energy saving brewing method

Related Child Applications (6)

Application Number Title Priority Date Filing Date
PCT/DK2009/050315 Continuation-In-Part WO2010063288A3 (en) 2008-12-03 2009-12-01 Barley and malt-derived beverages with low dimethyl sulfide level
US13132765 Continuation-In-Part US9834760B2 (en) 2008-12-03 2009-12-01 Barley and malt-derived beverages with low DMS level
US13141579 A-371-Of-International US9363959B2 (en) 2008-12-30 2009-12-28 Barley with reduced lipoxygenase activity and beverage prepared therefrom
PCT/DK2011/050186 Continuation-In-Part WO2011150933A3 (en) 2010-06-03 2011-05-31 Energy saving brewing method
US201113141579 A-371-Of-International 2011-09-14
US201213701604 Continuation-In-Part 2012-12-03

Publications (2)

Publication Number Publication Date
WO2010075860A2 true WO2010075860A2 (en) 2010-07-08
WO2010075860A3 true true WO2010075860A3 (en) 2011-07-14

Family

ID=41153271

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2009/050355 WO2010075860A3 (en) 2008-12-30 2009-12-28 Barley with reduced lipoxygenase activity and beverage prepared therefrom

Country Status (6)

Country Link
US (1) US9363959B2 (en)
EP (1) EP2384110B1 (en)
JP (1) JP5670347B2 (en)
CN (1) CN102333440B (en)
CA (1) CA2747225A1 (en)
WO (1) WO2010075860A3 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2600353T3 (en) 2010-06-03 2017-02-08 Carlsberg Breweries A/S Brewing process energy saving
CN103114129B (en) * 2012-11-08 2016-08-31 中国农业科学院作物科学研究所 One kind of barley lipoxygenase (lox-1) Synthesis of the defective gene polymorphism in molecular markers
CN103018388B (en) * 2013-01-21 2015-01-07 江苏省农业科学院 Method for judging ending point of sweet corn blanching with content of hexanal

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053721A1 (en) * 2000-12-29 2002-07-11 Carlsberg Research Laboratory Low-lipoxygenase 1 barley
US20030167544A1 (en) * 2000-12-29 2003-09-04 Douma Anna Christina Low lipoxygenase 1 barley
WO2004011591A1 (en) * 2002-07-25 2004-02-05 Novozymes A/S Mashing process
US20050204437A1 (en) * 2004-03-11 2005-09-15 Carlsberg A/S Barley for production of flavor-stable beverage
US20060005276A1 (en) * 2004-03-12 2006-01-05 Falco Saverio C Transgenic soybean seeds having reduced activity of lipoxygenases
US20070067871A1 (en) * 2005-09-07 2007-03-22 Monsanto Technology, L.L.C. Agronomically elite soybeans with high beta-conglycinin content

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195B1 (en) 1986-01-30 1990-11-27 Cetus Corp
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
DE4428978A1 (en) 1993-09-29 1995-03-30 Weissheimer Friedr Malzfab Process for producing a malt product for foods, in particular for beer production, and a malt product produced by this process
US6696294B1 (en) 1998-06-19 2004-02-24 Northwest Plant Breeding Co. Methods for generating and identifying mutant polyploid plants, and uses therefor
JP4113795B2 (en) 2003-03-25 2008-07-09 サッポロビール株式会社 Barley lipoxygenase-1 gene, methods Selection of barley, a method of manufacturing material for malt alcoholic beverages and malt alcoholic beverages
JP2006034129A (en) 2004-07-23 2006-02-09 Asahi Breweries Ltd Method for producing malt

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053721A1 (en) * 2000-12-29 2002-07-11 Carlsberg Research Laboratory Low-lipoxygenase 1 barley
US20030167544A1 (en) * 2000-12-29 2003-09-04 Douma Anna Christina Low lipoxygenase 1 barley
WO2004011591A1 (en) * 2002-07-25 2004-02-05 Novozymes A/S Mashing process
US20050204437A1 (en) * 2004-03-11 2005-09-15 Carlsberg A/S Barley for production of flavor-stable beverage
US20060005276A1 (en) * 2004-03-12 2006-01-05 Falco Saverio C Transgenic soybean seeds having reduced activity of lipoxygenases
US20070067871A1 (en) * 2005-09-07 2007-03-22 Monsanto Technology, L.L.C. Agronomically elite soybeans with high beta-conglycinin content

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DROST B W ET AL: "FLAVOR STABILITY", JOURNAL OF THE AMERICAN SOCIETY OF BREWING CHEMISTS, AMERICAN SOCIETY OF BREWING CHEMISTS, ST PAUL, MN, US, vol. 48, no. 4, 1 January 1990 (1990-01-01), pages 124 - 131, XP000926610, ISSN: 0361-0470 *
HIROTA N ET AL: "Brewing performance of malted lipoxygenase-1 null barley and effect on the flavor stability of beer", CEREAL CHEMISTRY, AMERICAN ASSOCIATION OF CEREAL CHEMISTS. MINNEAPOLIS, US, vol. 83, no. 3, 1 May 2006 (2006-05-01), pages 250 - 254, XP009124704, ISSN: 0009-0352 *
HIROTA N ET AL: "Characterization of lipoxygenase-1 null mutants in barley", THEORETICAL AND APPLIED GENETICS ; INTERNATIONAL JOURNAL OF PLANT BREEDING RESEARCH, SPRINGER, BERLIN, DE, vol. 111, no. 8, 1 November 2005 (2005-11-01), pages 1580 - 1584, XP019322107, ISSN: 1432-2242 *
HOTZEL HELMUT ET AL: "Recovery and characterization of residual DNA from beer as a prerequisite for the detection of genetically modified ingredients", EUROPEAN FOOD RESEARCH AND TECHNOLOGY, vol. 209, no. 3-4, 1999, pages 192 - 196, XP002635202, ISSN: 1438-2377 *
HUGUES MIREILLE ET AL: "Two Lipoxygenases from Germinated Barley-Heat and Kilning Stability", JOURNAL OF FOOD SCIENCE, vol. 59, no. 4, 1994, pages 885 - 889, XP002552212, ISSN: 0022-1147 *
KURODA H ET AL: "Characterization of factors that transform linoleic acid into di- and trihydroxyoctadecenoic acids in mash", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, ELSEVIER, AMSTERDAM, NL, vol. 93, no. 1, 1 January 2002 (2002-01-01), pages 73 - 77, XP002980834, ISSN: 1389-1723 *
MECHELEN VAN J R ET AL: "MOLECULAR CHARACTERIZATION OF TWO LIPOXYGENASES FROM BARLEY", PLANT MOLECULAR BIOLOGY, SPRINGER, DORDRECHT, NL, vol. 39, no. 6, 1 April 1999 (1999-04-01), pages 1283 - 1298, XP001015731, ISSN: 0167-4412 *
RUTGERSSON A ET AL: "OPTIMIZATION OF TEMPERATURE, TIME, AND LACTIC ACID CONCENTRATION TOINACTIVATE LIPOXYGENASE AND LIPASE AND PRESERVE PHYTASE ACTIVITY INBARLEY (CV. BLENHEIM) DURING SOAKING", CEREAL CHEMISTRY, AMERICAN ASSOCIATION OF CEREAL CHEMISTS. MINNEAPOLIS, US, vol. 74, no. 6, 1 January 1997 (1997-01-01), pages 727 - 732, XP000867116, ISSN: 0009-0352 *
WAN HENG WANG ET AL: "Molecular basis of a null mutation in soybean lipoxygenase 2: substitution of glutamine for an iron-ligand histidine", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 91, no. 13, 1 January 1994 (1994-01-01), pages 5828 - 5832, XP002175448, ISSN: 0027-8424 *

Also Published As

Publication number Publication date Type
US20110318469A1 (en) 2011-12-29 application
CA2747225A1 (en) 2010-07-08 application
JP2012513744A (en) 2012-06-21 application
JP5670347B2 (en) 2015-02-18 grant
EP2384110A2 (en) 2011-11-09 application
CN102333440A (en) 2012-01-25 application
US9363959B2 (en) 2016-06-14 grant
CN102333440B (en) 2014-07-23 grant
WO2010075860A2 (en) 2010-07-08 application
EP2384110B1 (en) 2016-04-20 grant

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