WO2010061319A1 - Generation of a multicolour image of an unstained biological specimen - Google Patents
Generation of a multicolour image of an unstained biological specimen Download PDFInfo
- Publication number
- WO2010061319A1 WO2010061319A1 PCT/IB2009/055159 IB2009055159W WO2010061319A1 WO 2010061319 A1 WO2010061319 A1 WO 2010061319A1 IB 2009055159 W IB2009055159 W IB 2009055159W WO 2010061319 A1 WO2010061319 A1 WO 2010061319A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- substance
- image
- images
- specimen
- colour
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A63—SPORTS; GAMES; AMUSEMENTS
- A63B—APPARATUS FOR PHYSICAL TRAINING, GYMNASTICS, SWIMMING, CLIMBING, OR FENCING; BALL GAMES; TRAINING EQUIPMENT
- A63B43/00—Balls with special arrangements
- A63B43/02—Balls with special arrangements with a handle
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T11/00—2D [Two Dimensional] image generation
- G06T11/001—Texturing; Colouring; Generation of texture or colour
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T5/00—Image enhancement or restoration
- G06T5/50—Image enhancement or restoration by the use of more than one image, e.g. averaging, subtraction
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/90—Determination of colour characteristics
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10056—Microscopic image
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10141—Special mode during image acquisition
- G06T2207/10152—Varying illumination
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Color Image Communication Systems (AREA)
- Image Processing (AREA)
- Editing Of Facsimile Originals (AREA)
- Facsimile Image Signal Circuits (AREA)
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011538081A JP2012510069A (en) | 2008-11-27 | 2009-11-19 | Generation of multicolor images of unstained biological samples |
BRPI0916094A BRPI0916094A2 (en) | 2008-11-27 | 2009-11-19 | method of generating a multicolored image of an uncolored biological specimen, data carrier, and system for generating a multicolored image of an uncolored specimen |
US13/131,329 US9041792B2 (en) | 2008-11-27 | 2009-11-19 | Generation of a multicolour image of an unstained biological specimen |
EP09774741.4A EP2370951B1 (en) | 2008-11-27 | 2009-11-19 | Generation of a multicolour image of an unstained biological specimen |
CN200980147271.7A CN102227747B (en) | 2008-11-27 | 2009-11-19 | Generation of multicolour image of unstained biological specimen |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08305854.5 | 2008-11-27 | ||
EP08305854 | 2008-11-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2010061319A1 true WO2010061319A1 (en) | 2010-06-03 |
Family
ID=41510586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2009/055159 WO2010061319A1 (en) | 2008-11-27 | 2009-11-19 | Generation of a multicolour image of an unstained biological specimen |
Country Status (6)
Country | Link |
---|---|
US (1) | US9041792B2 (en) |
EP (1) | EP2370951B1 (en) |
JP (1) | JP2012510069A (en) |
CN (1) | CN102227747B (en) |
BR (1) | BRPI0916094A2 (en) |
WO (1) | WO2010061319A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2827772A1 (en) * | 2012-03-19 | 2015-01-28 | Genetic Innovations Inc. | Devices, systems, and methods for virtual staining |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
CN106840812B (en) | 2011-12-29 | 2019-12-17 | 思迪赛特诊断有限公司 | Methods and systems for detecting pathogens in biological samples |
US9173570B2 (en) | 2012-04-12 | 2015-11-03 | Thomas Nathan Millikan | Viewing and processing multispectral images |
EP2999988A4 (en) | 2013-05-23 | 2017-01-11 | S.D. Sight Diagnostics Ltd. | Method and system for imaging a cell sample |
IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
CN105659151B (en) | 2013-08-26 | 2018-06-29 | 思迪赛特诊断有限公司 | Digital micrograph System and method for |
US20150269314A1 (en) | 2014-03-20 | 2015-09-24 | Rudjer Boskovic Institute | Method and apparatus for unsupervised segmentation of microscopic color image of unstained specimen and digital staining of segmented histological structures |
WO2015195642A1 (en) * | 2014-06-16 | 2015-12-23 | Siemens Healthcare Diagnostics Inc. | Analyzing digital holographic microscopy data for hematology applications |
EP3186778B1 (en) | 2014-08-27 | 2023-01-11 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
CN104820994B (en) * | 2015-04-20 | 2017-11-28 | 陕西科技大学 | A kind of analysis method suitable for continuous high-resolution-ration transmission electric-lens image |
CA3021538C (en) * | 2015-06-11 | 2023-09-26 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Systems and methods for finding regions of interest in hematoxylin and eosin (h&e) stained tissue images and quantifying intratumor cellular spatial heterogeneity in multiplexed/hyperplexed fluorescence tissue images |
RU2718427C2 (en) * | 2015-07-16 | 2020-04-02 | Конинклейке Филипс Н.В. | Digital pathology system |
EP3350644B1 (en) | 2015-09-17 | 2021-04-28 | S.D. Sight Diagnostics Ltd. | Methods and apparatus for detecting an entity in a bodily sample |
US11733150B2 (en) | 2016-03-30 | 2023-08-22 | S.D. Sight Diagnostics Ltd. | Distinguishing between blood sample components |
JP6942148B2 (en) | 2016-05-11 | 2021-09-29 | エス.ディー.サイト ダイアグノスティクス リミテッド | Performing optical measurements on the sample |
WO2017195205A1 (en) | 2016-05-11 | 2017-11-16 | S.D. Sight Diagnostics Ltd | Sample carrier for optical measurements |
WO2019097387A1 (en) | 2017-11-14 | 2019-05-23 | S.D. Sight Diagnostics Ltd | Sample carrier for optical measurements |
CN111433817A (en) * | 2017-12-15 | 2020-07-17 | 威里利生命科学有限责任公司 | Generating a virtual stain image of an unstained sample |
CN109061131A (en) * | 2018-06-29 | 2018-12-21 | 志诺维思(北京)基因科技有限公司 | Dye picture processing method and processing device |
US11354804B1 (en) | 2019-09-27 | 2022-06-07 | Verily Life Sciences Llc | Transforming multispectral images to enhanced resolution images enabled by machine learning |
JP2022550916A (en) * | 2019-10-10 | 2022-12-05 | ジョージア テック リサーチ コーポレイション | Label-free hematological and histopathological analysis using deep UV microscopy |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000067635A1 (en) | 1999-05-07 | 2000-11-16 | Applied Spectral Imaging Ltd. | Spectral bio-imaging of the eye |
US6750964B2 (en) | 1999-08-06 | 2004-06-15 | Cambridge Research And Instrumentation, Inc. | Spectral imaging methods and systems |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5784162A (en) * | 1993-08-18 | 1998-07-21 | Applied Spectral Imaging Ltd. | Spectral bio-imaging methods for biological research, medical diagnostics and therapy |
US6198532B1 (en) * | 1991-02-22 | 2001-03-06 | Applied Spectral Imaging Ltd. | Spectral bio-imaging of the eye |
US6690817B1 (en) * | 1993-08-18 | 2004-02-10 | Applied Spectral Imaging Ltd. | Spectral bio-imaging data for cell classification using internal reference |
IL138123A0 (en) * | 2000-08-28 | 2001-10-31 | Accuramed 1999 Ltd | Medical decision support system and method |
WO2002037938A2 (en) * | 2000-10-24 | 2002-05-16 | Oncosis Llc | Method and device for selectively targeting cells within a three -dimensional specimen |
US7133543B2 (en) * | 2001-06-12 | 2006-11-07 | Applied Imaging Corporation | Automated scanning method for pathology samples |
US7133547B2 (en) * | 2002-01-24 | 2006-11-07 | Tripath Imaging, Inc. | Method for quantitative video-microscopy and associated system and computer software program product |
US7430355B2 (en) * | 2003-12-08 | 2008-09-30 | University Of Cincinnati | Light emissive signage devices based on lightwave coupling |
JP4192867B2 (en) * | 2004-08-30 | 2008-12-10 | ソニー株式会社 | PHYSICAL INFORMATION ACQUISITION DEVICE, PHYSICAL QUANTITY DISTRIBUTION DETECTION SEMICONDUCTOR DEVICE HAVING MULTIPLE UNIT COMPONENTS ARRAY, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE |
DE102005014152A1 (en) * | 2005-03-29 | 2006-10-12 | Diegel, Günther Georg | Apparatus and method for displaying body colors |
CN101176116B (en) * | 2005-05-13 | 2010-08-25 | 三路影像公司 | Methods of chromogen separation-based image analysis |
US8249326B2 (en) | 2005-11-25 | 2012-08-21 | British Columbia Cancer Agency Branch | Apparatus and methods for automated assessment of tissue pathology |
CN100554925C (en) * | 2005-12-10 | 2009-10-28 | 王海波 | Medical automatic sputum smear dyeing instrument and sputum smear dyeing method |
WO2008075266A2 (en) * | 2006-12-19 | 2008-06-26 | Philips Intellectual Property & Standards Gmbh | Colour sequential flash for digital image acquisition |
-
2009
- 2009-11-19 CN CN200980147271.7A patent/CN102227747B/en not_active Expired - Fee Related
- 2009-11-19 BR BRPI0916094A patent/BRPI0916094A2/en not_active Application Discontinuation
- 2009-11-19 JP JP2011538081A patent/JP2012510069A/en active Pending
- 2009-11-19 EP EP09774741.4A patent/EP2370951B1/en not_active Not-in-force
- 2009-11-19 WO PCT/IB2009/055159 patent/WO2010061319A1/en active Application Filing
- 2009-11-19 US US13/131,329 patent/US9041792B2/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000067635A1 (en) | 1999-05-07 | 2000-11-16 | Applied Spectral Imaging Ltd. | Spectral bio-imaging of the eye |
US6750964B2 (en) | 1999-08-06 | 2004-06-15 | Cambridge Research And Instrumentation, Inc. | Spectral imaging methods and systems |
Non-Patent Citations (5)
Title |
---|
CHUNG A ET AL.: "Advanced Optical Imaging Requiring No Contrast Agents-A New Armamentarium for Medicine and Surgery", CURRENT SURGERY, WILIAMS AND WILKINS, vol. 62, no. 3, 1 May 2005 (2005-05-01), pages 365 - 370, XP004910715, DOI: doi:10.1016/j.cursur.2004.12.011 |
CHUNG A ET AL: "Advanced Optical Imaging Requiring No Contrast Agents-A New Armamentarium for Medicine and Surgery", CURRENT SURGERY, WILIAMS AND WILKINS, BALTIMORE, US, vol. 62, no. 3, 1 May 2005 (2005-05-01), pages 365 - 370, XP004910715, ISSN: 0149-7944 * |
PINKY A BAUTISTA ET AL.: "OPTICAL REVIEW", vol. 12, 1 January 2005, SPRINGER, article "Digital Staining of Unstained Pathological Tissue Samples through Spectral Transmittance Classification", pages: 7 - 14 |
PINKY A BAUTISTA ET AL: "Digital Staining of Unstained Pathological Tissue Samples through Spectral Transmittance Classification", OPTICAL REVIEW, SPRINGER, BERLIN, DE, vol. 12, no. 1, 1 January 2005 (2005-01-01), pages 7 - 14, XP019353245, ISSN: 1349-9432 * |
T. ABE ET AL.: "Colour Correction of Pathological Images Based on Dye Amount Quantification", OPTICAL REVIEW, vol. 12, no. 4, 2005, pages 293 - 300 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2827772A1 (en) * | 2012-03-19 | 2015-01-28 | Genetic Innovations Inc. | Devices, systems, and methods for virtual staining |
EP2827772A4 (en) * | 2012-03-19 | 2015-01-28 | Genetic Innovations Inc | Devices, systems, and methods for virtual staining |
US10729325B2 (en) | 2012-03-19 | 2020-08-04 | Genetic Innovations, Inc. | Devices, systems, and methods for virtual staining |
US11684264B2 (en) | 2012-03-19 | 2023-06-27 | Genetic Innovations, Inc. | Devices, systems, and methods for virtual staining |
EP4321889A3 (en) * | 2012-03-19 | 2024-03-20 | Genetic Innovations Inc. | Devices, systems, and methods for virtual staining |
Also Published As
Publication number | Publication date |
---|---|
BRPI0916094A2 (en) | 2015-11-17 |
CN102227747B (en) | 2014-06-04 |
JP2012510069A (en) | 2012-04-26 |
EP2370951A1 (en) | 2011-10-05 |
EP2370951B1 (en) | 2016-10-05 |
US20110228072A1 (en) | 2011-09-22 |
CN102227747A (en) | 2011-10-26 |
US9041792B2 (en) | 2015-05-26 |
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