WO2009148821A3 - Endoprosthesis coating - Google Patents

Endoprosthesis coating Download PDF

Info

Publication number
WO2009148821A3
WO2009148821A3 PCT/US2009/044597 US2009044597W WO2009148821A3 WO 2009148821 A3 WO2009148821 A3 WO 2009148821A3 US 2009044597 W US2009044597 W US 2009044597W WO 2009148821 A3 WO2009148821 A3 WO 2009148821A3
Authority
WO
WIPO (PCT)
Prior art keywords
endoprosthesis
polymeric particles
deposited
coating
layer
Prior art date
Application number
PCT/US2009/044597
Other languages
French (fr)
Other versions
WO2009148821A2 (en
Inventor
Scott R. Schewe
Jan Weber
Michele Zoromski
Robert W. Warner
Original Assignee
Boston Scientific Scimed, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Scimed, Inc. filed Critical Boston Scientific Scimed, Inc.
Priority to EP09758982A priority Critical patent/EP2310064A2/en
Priority to JP2011511714A priority patent/JP2011521716A/en
Publication of WO2009148821A2 publication Critical patent/WO2009148821A2/en
Publication of WO2009148821A3 publication Critical patent/WO2009148821A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)

Abstract

An endoprosthesis, e.g., a stent (e.g., a drug eluting stent), includes a surface, a first layer having a polyelectrolyte deposited on the surface, a plurality of polymeric particles deposited on the first layer, and a coating of a porous material deposited on the plurality of polymeric particles. At least one particle of the plurality of polymeric particles includes a polymer matrix and a drug distributed in the polymer matrix. A method of making the endoprosthesis is also disclosed.
PCT/US2009/044597 2008-05-29 2009-05-20 Endoprosthesis coating WO2009148821A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09758982A EP2310064A2 (en) 2008-05-29 2009-05-20 Endoprosthesis coating
JP2011511714A JP2011521716A (en) 2008-05-29 2009-05-20 Prosthetic coating

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5691208P 2008-05-29 2008-05-29
US61/056,912 2008-05-29

Publications (2)

Publication Number Publication Date
WO2009148821A2 WO2009148821A2 (en) 2009-12-10
WO2009148821A3 true WO2009148821A3 (en) 2010-09-02

Family

ID=40874901

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/044597 WO2009148821A2 (en) 2008-05-29 2009-05-20 Endoprosthesis coating

Country Status (4)

Country Link
US (1) US20090299468A1 (en)
EP (1) EP2310064A2 (en)
JP (1) JP2011521716A (en)
WO (1) WO2009148821A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8449603B2 (en) 2008-06-18 2013-05-28 Boston Scientific Scimed, Inc. Endoprosthesis coating

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2185103B1 (en) 2007-08-03 2014-02-12 Boston Scientific Scimed, Inc. Coating for medical device having increased surface area
EP2271380B1 (en) 2008-04-22 2013-03-20 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
US8932346B2 (en) 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US9849005B2 (en) * 2012-04-16 2017-12-26 Biotronik Ag Implant and method for manufacturing same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115496A1 (en) * 2004-05-20 2005-12-08 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US20060100696A1 (en) * 2004-11-10 2006-05-11 Atanasoska Ljiljana L Medical devices and methods of making the same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019803A1 (en) * 1992-03-31 1993-10-14 Boston Scientific Corporation Medical wire
US7713297B2 (en) * 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US5980566A (en) * 1998-04-11 1999-11-09 Alt; Eckhard Vascular and endoluminal stents with iridium oxide coating
US20030077200A1 (en) * 2000-07-07 2003-04-24 Craig Charles H. Enhanced radiopaque alloy stent
US20030018380A1 (en) * 2000-07-07 2003-01-23 Craig Charles H. Platinum enhanced alloy and intravascular or implantable medical devices manufactured therefrom
US20020144757A1 (en) * 2000-07-07 2002-10-10 Craig Charles Horace Stainless steel alloy with improved radiopaque characteristics
US7794494B2 (en) * 2002-10-11 2010-09-14 Boston Scientific Scimed, Inc. Implantable medical devices
US20040143317A1 (en) * 2003-01-17 2004-07-22 Stinson Jonathan S. Medical devices
WO2004069169A2 (en) * 2003-01-31 2004-08-19 Scimed Life Systems, Inc. Localized drug delivery using drug-loaded nanocapsules and implantable device coated with the same
US20050070990A1 (en) * 2003-09-26 2005-03-31 Stinson Jonathan S. Medical devices and methods of making same
US7744644B2 (en) * 2004-03-19 2010-06-29 Boston Scientific Scimed, Inc. Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release
US7727273B2 (en) * 2005-01-13 2010-06-01 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
US20070005024A1 (en) * 2005-06-10 2007-01-04 Jan Weber Medical devices having superhydrophobic surfaces, superhydrophilic surfaces, or both
CA2655793A1 (en) * 2006-06-29 2008-01-03 Boston Scientific Limited Medical devices with selective coating

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115496A1 (en) * 2004-05-20 2005-12-08 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US20060100696A1 (en) * 2004-11-10 2006-05-11 Atanasoska Ljiljana L Medical devices and methods of making the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8449603B2 (en) 2008-06-18 2013-05-28 Boston Scientific Scimed, Inc. Endoprosthesis coating

Also Published As

Publication number Publication date
US20090299468A1 (en) 2009-12-03
EP2310064A2 (en) 2011-04-20
WO2009148821A2 (en) 2009-12-10
JP2011521716A (en) 2011-07-28

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