WO2009121054A3 - Rapid diagnosis of a disease condition using infrared spectroscopy - Google Patents

Rapid diagnosis of a disease condition using infrared spectroscopy Download PDF

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Publication number
WO2009121054A3
WO2009121054A3 PCT/US2009/038771 US2009038771W WO2009121054A3 WO 2009121054 A3 WO2009121054 A3 WO 2009121054A3 US 2009038771 W US2009038771 W US 2009038771W WO 2009121054 A3 WO2009121054 A3 WO 2009121054A3
Authority
WO
WIPO (PCT)
Prior art keywords
classification models
humans
exemplary
cats
infrared spectroscopy
Prior art date
Application number
PCT/US2009/038771
Other languages
French (fr)
Other versions
WO2009121054A2 (en
Inventor
Charles A. Buffington
Daniel Emilio Rubio-Diaz
Luis E. Rodriguez-Saona
Judi L. Stella
Original Assignee
The Ohio State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Ohio State University filed Critical The Ohio State University
Priority to CN2009801189978A priority Critical patent/CN102046070A/en
Priority to EP09726207A priority patent/EP2262412A2/en
Priority to US12/933,960 priority patent/US8309931B2/en
Priority to CA2719489A priority patent/CA2719489A1/en
Publication of WO2009121054A2 publication Critical patent/WO2009121054A2/en
Publication of WO2009121054A3 publication Critical patent/WO2009121054A3/en
Priority to US13/108,536 priority patent/US8614419B2/en
Priority to US13/662,011 priority patent/US8822928B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3563—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N2021/3595—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using FTIR
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Reliable and rapid diagnostic methods for many functional syndromes (FS) such as Bladder Pain Syndrome/ Interstitial Cystitis (IC) are not available. Exemplary embodiments include rapid and accurate methods for diagnosing FS in humans and domestic cats using infrared microspectroscopy (IRMS). Exemplary methods utilize Soft Independent Modeling by Class Analogy (SIMCA) to create classification models. Exemplary methods utilize classification models to classify a test subject's condition (e.g., healthy/sick). Using these classification models, various embodiments enable diagnosis based on spectra data from a fluid biomedical specimen. Exemplary embodiments may be useful to rapidly diagnose IC and various other conditions in humans, cats, and/or other mammals.
PCT/US2009/038771 2008-03-28 2009-03-30 Rapid diagnosis of a disease condition using infrared spectroscopy WO2009121054A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CN2009801189978A CN102046070A (en) 2008-03-28 2009-03-30 Rapid diagnosis of a disease condition using infrared spectroscopy
EP09726207A EP2262412A2 (en) 2008-03-28 2009-03-30 Rapid diagnosis of a disease condition using infrared spectroscopy
US12/933,960 US8309931B2 (en) 2008-03-28 2009-03-30 Rapid diagnosis of a disease condition using infrared spectroscopy
CA2719489A CA2719489A1 (en) 2008-03-28 2009-03-30 Rapid diagnosis of a disease condition using infrared spectroscopy
US13/108,536 US8614419B2 (en) 2008-03-28 2011-05-16 Rapid diagnosis of a disease condition using infrared spectroscopy
US13/662,011 US8822928B2 (en) 2008-03-28 2012-10-26 Rapid diagnosis of a disease condition using infrared spectroscopy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4062708P 2008-03-28 2008-03-28
US61/040,627 2008-03-28

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US12/933,960 A-371-Of-International US8309931B2 (en) 2008-03-28 2009-03-30 Rapid diagnosis of a disease condition using infrared spectroscopy
US13/108,536 Continuation-In-Part US8614419B2 (en) 2008-03-28 2011-05-16 Rapid diagnosis of a disease condition using infrared spectroscopy
US13/662,011 Continuation US8822928B2 (en) 2008-03-28 2012-10-26 Rapid diagnosis of a disease condition using infrared spectroscopy

Publications (2)

Publication Number Publication Date
WO2009121054A2 WO2009121054A2 (en) 2009-10-01
WO2009121054A3 true WO2009121054A3 (en) 2010-01-07

Family

ID=41114820

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/038771 WO2009121054A2 (en) 2008-03-28 2009-03-30 Rapid diagnosis of a disease condition using infrared spectroscopy

Country Status (5)

Country Link
US (2) US8309931B2 (en)
EP (1) EP2262412A2 (en)
CN (1) CN102046070A (en)
CA (1) CA2719489A1 (en)
WO (1) WO2009121054A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8614419B2 (en) 2008-03-28 2013-12-24 The Ohio State University Rapid diagnosis of a disease condition using infrared spectroscopy
CN102046070A (en) 2008-03-28 2011-05-04 俄亥俄州立大学 Rapid diagnosis of a disease condition using infrared spectroscopy
NZ624695A (en) * 2011-10-24 2016-03-31 Harvard College Enhancing diagnosis of disorder through artificial intelligence and mobile health technologies without compromising accuracy
JP2015525877A (en) 2012-06-28 2015-09-07 クイック エルエルシー Infrared light measuring apparatus, method, and system for portable smart device for analyzing substances
CN103149173B (en) * 2013-03-06 2015-06-17 上海交通大学 Method for rapidly detecting vibrio parahaemolyticus based on microscopic infrared spectrum technology
GB2528487A (en) * 2014-07-23 2016-01-27 Airbus Operations Ltd Apparatus and method for testing materials
GB2528488A (en) 2014-07-23 2016-01-27 Airbus Operations Ltd Method and apparatus for testing materials
EP3307143A4 (en) * 2015-06-12 2019-01-02 Georgia State University Research Foundation Atr-ftir for non-invasive detection of colitis
JP6618789B2 (en) * 2015-11-27 2019-12-11 サクラ精機株式会社 Analysis method and analyzer
WO2018089383A1 (en) * 2016-11-08 2018-05-17 University Of Southern California A hyperspectral imaging system
US11280732B2 (en) 2018-08-20 2022-03-22 Georgia State University Research Foundation, Inc. Detection of melanoma and lymphoma by ATR-FTIR spectroscopy
CN109745017B (en) * 2019-01-30 2021-04-06 中国科学院电子学研究所 A system, device and method for real-time monitoring of animal physiological information and state

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5473160A (en) * 1994-08-10 1995-12-05 National Research Council Of Canada Method for diagnosing arthritic disorders by infrared spectroscopy
US6270986B1 (en) * 1999-02-16 2001-08-07 Patrick T. T. Wong Method of preserving biological tissue specimens and method of infrared spectroscopic analysis which avoids the effects of polymorphs
US6620621B1 (en) * 1995-11-13 2003-09-16 Digilab Method for the detection of cellular abnormalities using fourier transform infrared spectroscopy
US6793624B2 (en) * 2000-03-31 2004-09-21 Japan, As Represented By President Of Kobe University Method and apparatus for detecting mastitis by using visible light rays and/or near infrared light

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US6146897A (en) 1995-11-13 2000-11-14 Bio-Rad Laboratories Method for the detection of cellular abnormalities using Fourier transform infrared spectroscopy
PL335543A1 (en) * 1997-03-08 2000-04-25 Univ Dundee Prenatal diagnosing methods
US7790865B1 (en) * 1999-02-02 2010-09-07 Qiagen North American Holdings, Inc Eluting reagents, methods and kits for isolating DNA
FR2811084B1 (en) 2000-06-29 2002-10-25 Bioalliance Pharma METHOD FOR IDENTIFYING A FUNCTIONAL BIOLOGICAL CHARACTERISTIC OF A LIVING MATERIAL
US6749565B2 (en) * 2000-07-08 2004-06-15 Victor Chudner Method for blood infrared spectroscopy diagnosing of inner organs pathology
US6841388B2 (en) * 2000-12-05 2005-01-11 Vysis, Inc. Method and system for diagnosing pathology in biological samples by detection of infrared spectral markers
AU2002353914A1 (en) * 2001-10-29 2003-05-12 Optiscan Biomedical Corporation Window assembly for thermal gradient spectrometer
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5473160A (en) * 1994-08-10 1995-12-05 National Research Council Of Canada Method for diagnosing arthritic disorders by infrared spectroscopy
US6620621B1 (en) * 1995-11-13 2003-09-16 Digilab Method for the detection of cellular abnormalities using fourier transform infrared spectroscopy
US6270986B1 (en) * 1999-02-16 2001-08-07 Patrick T. T. Wong Method of preserving biological tissue specimens and method of infrared spectroscopic analysis which avoids the effects of polymorphs
US6793624B2 (en) * 2000-03-31 2004-09-21 Japan, As Represented By President Of Kobe University Method and apparatus for detecting mastitis by using visible light rays and/or near infrared light

Also Published As

Publication number Publication date
EP2262412A2 (en) 2010-12-22
US8309931B2 (en) 2012-11-13
US20130153770A1 (en) 2013-06-20
CN102046070A (en) 2011-05-04
WO2009121054A2 (en) 2009-10-01
US8822928B2 (en) 2014-09-02
CA2719489A1 (en) 2009-10-01
US20110168897A1 (en) 2011-07-14

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