WO2009076425A3 - Methods of analyzing wound samples - Google Patents

Methods of analyzing wound samples Download PDF

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Publication number
WO2009076425A3
WO2009076425A3 PCT/US2008/086204 US2008086204W WO2009076425A3 WO 2009076425 A3 WO2009076425 A3 WO 2009076425A3 US 2008086204 W US2008086204 W US 2008086204W WO 2009076425 A3 WO2009076425 A3 WO 2009076425A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
wound samples
analyzing wound
analyzing
samples
Prior art date
Application number
PCT/US2008/086204
Other languages
French (fr)
Other versions
WO2009076425A2 (en
Inventor
Stephanie F. Bernatchez
Katri M. Huikko
Original Assignee
3M Innovative Properties Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Company filed Critical 3M Innovative Properties Company
Priority to US12/747,687 priority Critical patent/US20100273666A1/en
Priority to EP08860413A priority patent/EP2235541A2/en
Priority to JP2010538118A priority patent/JP2011506971A/en
Publication of WO2009076425A2 publication Critical patent/WO2009076425A2/en
Publication of WO2009076425A3 publication Critical patent/WO2009076425A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Physiology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

A method of analyzing wound samples is provided. The analysis typically involves the use of mass spectrometry.
PCT/US2008/086204 2007-12-13 2008-12-10 Methods of analyzing wound samples WO2009076425A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/747,687 US20100273666A1 (en) 2007-12-13 2008-12-10 Methods of analyzing wound samples
EP08860413A EP2235541A2 (en) 2007-12-13 2008-12-10 Methods of analyzing wound samples
JP2010538118A JP2011506971A (en) 2007-12-13 2008-12-10 Method for analyzing wound samples

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1348807P 2007-12-13 2007-12-13
US61/013,488 2007-12-13

Publications (2)

Publication Number Publication Date
WO2009076425A2 WO2009076425A2 (en) 2009-06-18
WO2009076425A3 true WO2009076425A3 (en) 2009-11-12

Family

ID=40756099

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/086204 WO2009076425A2 (en) 2007-12-13 2008-12-10 Methods of analyzing wound samples

Country Status (4)

Country Link
US (1) US20100273666A1 (en)
EP (1) EP2235541A2 (en)
JP (1) JP2011506971A (en)
WO (1) WO2009076425A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140166875A1 (en) 2010-09-02 2014-06-19 Wayne State University Systems and methods for high throughput solvent assisted ionization inlet for mass spectrometry
WO2012058248A2 (en) * 2010-10-25 2012-05-03 Wayne State University Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum
GB201021182D0 (en) * 2010-12-14 2011-01-26 Univ Cardiff Methdo and kit for the classification and prognosis of chronic wounds
GB2495899B (en) * 2011-07-04 2018-05-16 Thermo Fisher Scient Bremen Gmbh Identification of samples using a multi pass or multi reflection time of flight mass spectrometer
WO2013144672A1 (en) * 2012-03-30 2013-10-03 Société De Développement Et De Recherche Industrielle Method and kit for the classification and prognosis of wounds
WO2014005138A1 (en) * 2012-06-29 2014-01-03 Kerschensteiner Daniel A Colorimetric gelatinase assay
EP3726562B1 (en) 2015-03-06 2023-12-20 Micromass UK Limited Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
US10026599B2 (en) * 2015-03-06 2018-07-17 Micromass Uk Limited Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
CN107646089B (en) 2015-03-06 2020-12-08 英国质谱公司 Spectral analysis
US11454611B2 (en) 2016-04-14 2022-09-27 Micromass Uk Limited Spectrometric analysis of plants
CN109946367B (en) * 2017-12-20 2021-10-22 中国中医科学院医学实验中心 Method for identifying drug resistance of staphylococcus aureus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042774A2 (en) * 2001-11-13 2003-05-22 Caprion Pharmaceuticals Inc. Mass intensity profiling system and uses thereof
US20040157242A1 (en) * 2002-11-12 2004-08-12 Becton, Dickinson And Company Diagnosis of sepsis or SIRS using biomarker profiles

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177266B1 (en) * 1996-04-29 2001-01-23 The United States Of America As Represented By The Secretary Of The Army Rapid identification of bacteria by mass spectrometry
US5879635A (en) * 1997-03-31 1999-03-09 Nason; Frederic L. Reagent dispenser and related test kit for biological specimens
US7191068B2 (en) * 2003-03-25 2007-03-13 Proteogenix, Inc. Proteomic analysis of biological fluids
US8012693B2 (en) * 2003-12-16 2011-09-06 3M Innovative Properties Company Analysis of chemically crosslinked cellular samples
US20050196789A1 (en) * 2004-02-06 2005-09-08 Applera Corporation Preparation of biologically derived fluids for biomarker determination by mass spectrometry
US20110177492A1 (en) * 2005-06-16 2011-07-21 3M Innovative Properties Company Method of classifying chemically crosslinked cellular samples using mass spectra
EP1938231A1 (en) * 2005-09-19 2008-07-02 BG Medicine, Inc. Correlation analysis of biological systems

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042774A2 (en) * 2001-11-13 2003-05-22 Caprion Pharmaceuticals Inc. Mass intensity profiling system and uses thereof
US20040157242A1 (en) * 2002-11-12 2004-08-12 Becton, Dickinson And Company Diagnosis of sepsis or SIRS using biomarker profiles

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
CALDWELL R L ET AL: "TISSUE PROFILING BY MALDI MASS SPECTROMETRY REVEALS PROMINENT CALCIUM-BINDING PROTEINS IN THE PROTEOME OF REGENERATIVE MRL MOUSE WOUNDS", WOUND REPAIR AND REGENERATION, MOSBY-YEAR BOOK, ST. LOUIS, MO, US, vol. 14, no. 2, 1 March 2006 (2006-03-01), pages A56, XP009121111, ISSN: 1067-1927, [retrieved on 20070407] *
CALDWELL ROBERT L ET AL: "Tissue profiling MALDI mass spectrometry reveals prominent calcium-binding proteins in the proteome of regenerative MRL mouse wounds.", WOUND REPAIR AND REGENERATION : OFFICIAL PUBLICATION OF THE WOUND HEALING SOCIETY [AND] THE EUROPEAN TISSUE REPAIR SOCIETY 2008 MAY-JUN, vol. 16, no. 3, May 2008 (2008-05-01), pages 442 - 449, XP002540768, ISSN: 1524-475X *
FROHM M ET AL: "Biochemical and antibacterial analysis of human wound and blister fluid.", EUROPEAN JOURNAL OF BIOCHEMISTRY / FEBS 1 APR 1996, vol. 237, no. 1, 1 April 1996 (1996-04-01), pages 86 - 92, XP002540766, ISSN: 0014-2956 *
HUANG CHUN-MING ET AL: "In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteomics.", PROTEOMICS NOV 2006, vol. 6, no. 21, November 2006 (2006-11-01), pages 5805 - 5814, XP002540767, ISSN: 1615-9853 *
NANNEY LILLIAN B ET AL: "Novel approaches for understanding the mechanisms of wound repair", JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, vol. 11, no. 1, September 2006 (2006-09-01), pages 132 - 139, XP002540769, ISSN: 1087-0024 *
POLLINS ET AL: "Proteomic Investigation of Human Burn Wounds by 2D-Difference Gel Electrophoresis and Mass Spectrometry", JOURNAL OF SURGICAL RESEARCH, ACADEMIC PRESS INC., SAN DIEGO, CA, US, vol. 142, no. 1, 21 August 2007 (2007-08-21), pages 143 - 152, XP022208411, ISSN: 0022-4804 *
SIDDIQUI NIKHAT AHMED ET AL: "Proteome analysis using IEF in immobilized pH gradient gels followed by mass Spectrometry", MOLECULAR & CELLULAR PROTEOMICS, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US, vol. 3, no. 10, suppl, 1 October 2004 (2004-10-01), pages S89, XP009121011, ISSN: 1535-9476 *

Also Published As

Publication number Publication date
JP2011506971A (en) 2011-03-03
WO2009076425A2 (en) 2009-06-18
EP2235541A2 (en) 2010-10-06
US20100273666A1 (en) 2010-10-28

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