WO2009051417A3 - Phenanthrene lactam derivatives having anticancer activity and method for the preparation thereof - Google Patents
Phenanthrene lactam derivatives having anticancer activity and method for the preparation thereof Download PDFInfo
- Publication number
- WO2009051417A3 WO2009051417A3 PCT/KR2008/006110 KR2008006110W WO2009051417A3 WO 2009051417 A3 WO2009051417 A3 WO 2009051417A3 KR 2008006110 W KR2008006110 W KR 2008006110W WO 2009051417 A3 WO2009051417 A3 WO 2009051417A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- phenanthrene
- preparation
- anticancer activity
- lactam derivatives
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a phenanthrene lactam derivative having anticanter activity, a method for the preparation thereof, and a pharmaceutical composition comprising same.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2007-0104435 | 2007-10-17 | ||
KR1020070104435A KR101124350B1 (en) | 2007-10-17 | 2007-10-17 | Phenanthrene lactam derivatives having anticancer activity, method for preparing same and pharmaceutical composition containing same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009051417A2 WO2009051417A2 (en) | 2009-04-23 |
WO2009051417A3 true WO2009051417A3 (en) | 2009-06-04 |
Family
ID=40567963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2008/006110 WO2009051417A2 (en) | 2007-10-17 | 2008-10-16 | Phenanthrene lactam derivatives having anticancer activity and method for the preparation thereof |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR101124350B1 (en) |
WO (1) | WO2009051417A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018111050A1 (en) * | 2016-12-15 | 2018-06-21 | 한국생명공학연구원 | Pharmaceutical composition comprising phenanthrene-lactam-based compound as effective ingredient for preventing or treating dyrk-related disease |
CN106892859B (en) * | 2017-03-22 | 2019-06-25 | 河南大学 | Benzo [c, d] indoles -2 (H) -one-polyamines conjugate and its preparation method and application |
US10513515B2 (en) | 2017-08-25 | 2019-12-24 | Biotheryx, Inc. | Ether compounds and uses thereof |
WO2020023782A1 (en) | 2018-07-27 | 2020-01-30 | Biotheryx, Inc. | Bifunctional compounds as cdk modulators |
CN110498759A (en) * | 2019-09-12 | 2019-11-26 | 天津瑞岭化工有限公司 | The synthetic method of isoindoline ketone compound |
KR102405447B1 (en) * | 2020-02-28 | 2022-06-07 | 대한민국(질병관리청장) | 5-(2-Aminoethyl)-dibenzo[cd,f]-indol-4(5H)-one derivatives compound, preparation method thereof, and pharmaceutical composition for anti HIV-1 containing the same as an active ingredient |
US11897930B2 (en) | 2020-04-28 | 2024-02-13 | Anwita Biosciences, Inc. | Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications |
CN117940404A (en) * | 2021-09-13 | 2024-04-26 | 海南先声再明医药股份有限公司 | Tricyclic compounds as Cbl-b inhibitors |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4782077A (en) * | 1987-08-20 | 1988-11-01 | Monoclonetics International, Inc. | Taliscanin and other aristolactams for treating neurological disorders, Parkinson's disease, Alzheimer disease and impotence |
US20030045564A1 (en) * | 2000-10-19 | 2003-03-06 | Young-Joong Kim | Saururus chinensis extract for prevention and treatment of neurodegenerative disease |
-
2007
- 2007-10-17 KR KR1020070104435A patent/KR101124350B1/en not_active IP Right Cessation
-
2008
- 2008-10-16 WO PCT/KR2008/006110 patent/WO2009051417A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4782077A (en) * | 1987-08-20 | 1988-11-01 | Monoclonetics International, Inc. | Taliscanin and other aristolactams for treating neurological disorders, Parkinson's disease, Alzheimer disease and impotence |
US20030045564A1 (en) * | 2000-10-19 | 2003-03-06 | Young-Joong Kim | Saururus chinensis extract for prevention and treatment of neurodegenerative disease |
Non-Patent Citations (2)
Title |
---|
COUTURE A. ET AL.: "Synthesis and biological evaluation of aristolactams", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, 2002, pages 3557 - 3559 * |
KUMAR V. ET AL.: "Naturally occuring aristolactams, aristolochic acids and dioxoaporphines and their biological activities", NATURAL PRODUCT REPORTS, vol. 20, 2003, pages 565 - 583 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009051417A2 (en) | 2009-04-23 |
KR101124350B1 (en) | 2012-03-15 |
KR20090039038A (en) | 2009-04-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2009051417A3 (en) | Phenanthrene lactam derivatives having anticancer activity and method for the preparation thereof | |
IL189008A (en) | 1-naphthalenyl-3-azabicyclo[3.1.0]hexane derivatives, process for their preparation and pharmaceutical compositions comprising them | |
WO2008017346A3 (en) | Ascorbic acid derivatives, use thereof for the functionalization of matrices | |
HK1164292A1 (en) | Novel tricyclic derivative or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition containing the same | |
IL216171A (en) | Lipid compound, method for its preparation, a pharmaceutical composition and a lipid composition comprising the same and uses thereof | |
IL208203A (en) | 2,3-dihydro-pyrido-1,4-oxazine and 2,3-dihydro-4-oxa-1,9-diazaphenanthrene derivatives, processes for their preparation and pharmaceutical compositions comprising them | |
IL193772A0 (en) | 4-oxoquinoline derivatives,methods for the preparation thereof and pharmaceutical compositions containing the same | |
AP2384A (en) | 1,2,4,5-tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them. | |
WO2007097770A8 (en) | Metoprolol succinate e.r. tablets and methods for their preparation | |
IL213570A (en) | 8-alkoxy-s-triazolo[1,5-ɑ]pyridine derivatives and pharmaceutical compositions comprising them | |
WO2009051460A3 (en) | Peptide coupled ascorbic acid derivatives | |
WO2011009938A3 (en) | Stambomycin and derivatives, their production and their use as drugs | |
WO2008129501A3 (en) | Pharmaceutical compositions of duloxetine | |
EP2394993A4 (en) | Novel 2,6-substituted-3-nitropyridine derivative, method for preparing same, and pharmaceutical composition including same | |
WO2006134021A3 (en) | Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof | |
EP2292242A4 (en) | A scutellarin derivative, the preparing process, the pharmaceutical composition and the use thereof | |
EP2167490A4 (en) | Triazole derivatives having antifungal activity, method for the preparation thereof, and pharmaceutical composition comprising the same | |
PL2231598T3 (en) | Novel diazeniumdiolate derivatives, method for the preparation thereof and pharmaceutical compositions containing the same | |
IL186062A0 (en) | Indanyl-piperazine derivatives, method for preparing same and pharmaceutical compositions containing same | |
AP2007004223A0 (en) | Novel phenyl-pyridinyl-piperazine derivatives, a method for the production thereof and pharmaceutical compositions containing said derivatives | |
WO2011014003A3 (en) | (+)-3-hydroxymorphinan derivatives as neuroprotectants | |
WO2009026257A8 (en) | Methods and compositions for controlling the bioavailability of poorly soluble drugs | |
ZA200902414B (en) | Indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them | |
IL199078A (en) | Substituted quinoline derivatives, pharmaceutical compositions, combinations and products comprising them, uses thereof and processes for their preparation | |
WO2009013594A3 (en) | Process for the preparation of controlled-release solid formulations containing oxcarbazepine, and formulations obtainable by said process |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 08838855 Country of ref document: EP Kind code of ref document: A2 |
|
DPE1 | Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101) | ||
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 08838855 Country of ref document: EP Kind code of ref document: A2 |