WO2009016069A2 - Stable liquid pharmaceutical composition based on trazodone - Google Patents
Stable liquid pharmaceutical composition based on trazodone Download PDFInfo
- Publication number
- WO2009016069A2 WO2009016069A2 PCT/EP2008/059605 EP2008059605W WO2009016069A2 WO 2009016069 A2 WO2009016069 A2 WO 2009016069A2 EP 2008059605 W EP2008059605 W EP 2008059605W WO 2009016069 A2 WO2009016069 A2 WO 2009016069A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- peg
- pharmaceutical composition
- composition according
- trazodone
- polyethylene glycol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA201070194A EA016822B1 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
SI200830897T SI2182920T1 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
DK08775278.8T DK2182920T3 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
MX2010001092A MX2010001092A (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone. |
CA2692975A CA2692975C (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
US12/667,694 US10292931B2 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
KR1020107002151A KR101493370B1 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
PL08775278T PL2182920T3 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
BRPI0814658-6A2A BRPI0814658A2 (en) | 2007-07-31 | 2008-07-22 | STABLE NET PHARMACEUTICAL COMPOSITION |
AU2008281858A AU2008281858B2 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
ES08775278T ES2399569T3 (en) | 2007-07-31 | 2008-07-22 | Trazodone-based stable liquid pharmaceutical composition |
JP2010518618A JP5426548B2 (en) | 2007-07-31 | 2008-07-22 | Trazodone-based stable liquid pharmaceutical composition |
EP08775278A EP2182920B1 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
UAA201000864A UA102376C2 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
CN2008801012992A CN101784257B (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
IL203167A IL203167A (en) | 2007-07-31 | 2010-01-06 | Stable liquid pharmaceutical composition based on trazodone |
HK10104941.0A HK1138207A1 (en) | 2007-07-31 | 2010-05-19 | Stable liquid pharmaceutical composition based on trazodone |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT001573A ITMI20071573A1 (en) | 2007-07-31 | 2007-07-31 | LIQUID PHARMACEUTICAL COMPOSITION STABLE ON THE BASIS OF TRAZODONE |
ITMI2007A001573 | 2007-07-31 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2009016069A2 true WO2009016069A2 (en) | 2009-02-05 |
WO2009016069A3 WO2009016069A3 (en) | 2009-03-19 |
WO2009016069A4 WO2009016069A4 (en) | 2009-05-14 |
Family
ID=38858941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/059605 WO2009016069A2 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
Country Status (25)
Country | Link |
---|---|
US (1) | US10292931B2 (en) |
EP (2) | EP2182920B1 (en) |
JP (1) | JP5426548B2 (en) |
KR (1) | KR101493370B1 (en) |
CN (1) | CN101784257B (en) |
AR (1) | AR068327A1 (en) |
AU (1) | AU2008281858B2 (en) |
BR (1) | BRPI0814658A2 (en) |
CA (1) | CA2692975C (en) |
CY (1) | CY1116189T1 (en) |
DK (2) | DK2182920T3 (en) |
EA (1) | EA016822B1 (en) |
ES (2) | ES2531241T3 (en) |
GE (1) | GEP20125525B (en) |
HK (2) | HK1176280A1 (en) |
HR (1) | HRP20150349T1 (en) |
IL (1) | IL203167A (en) |
IT (1) | ITMI20071573A1 (en) |
MX (1) | MX2010001092A (en) |
PL (2) | PL2182920T3 (en) |
PT (2) | PT2494955E (en) |
SG (1) | SG183659A1 (en) |
SI (2) | SI2182920T1 (en) |
UA (1) | UA102376C2 (en) |
WO (1) | WO2009016069A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012072665A1 (en) | 2010-11-30 | 2012-06-07 | Pharmaneuroboost N.V. | Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors |
WO2021058810A1 (en) | 2019-09-26 | 2021-04-01 | Angelini S.P.A. | Pediatric trazodone compositions and method of treatment thereof |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20071603A1 (en) | 2007-08-03 | 2009-02-04 | Acraf | TRAZODONE AND CHLORIDATED TRAZODONE IN PURIFIED FORM |
RU2706700C1 (en) * | 2019-09-24 | 2019-11-20 | Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" | Pharmaceutical composition for correcting behavior of cats and dogs in stress situations |
CN111568861A (en) * | 2020-05-25 | 2020-08-25 | 河北科星药业有限公司 | Bromhexine hydrochloride oral liquid for livestock and poultry as well as preparation method and application thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4154832A (en) * | 1974-08-26 | 1979-05-15 | Bruno Silvestrini | Novel treatment for acute organic cerebral syndromes (strokes) |
IT1233412B (en) * | 1987-12-02 | 1992-03-30 | Acraf | USE OF TRAZODONE |
BR9912395A (en) * | 1998-07-24 | 2001-10-16 | Seo Hong Yoo | Preparation of dosage forms of clear aqueous solution with bile acids |
AU2003903597A0 (en) | 2003-07-11 | 2003-07-24 | Jakov Vaisman | Treatment of premature ejaculation |
ITMI20071603A1 (en) | 2007-08-03 | 2009-02-04 | Acraf | TRAZODONE AND CHLORIDATED TRAZODONE IN PURIFIED FORM |
-
2007
- 2007-07-31 IT IT001573A patent/ITMI20071573A1/en unknown
-
2008
- 2008-07-22 CA CA2692975A patent/CA2692975C/en active Active
- 2008-07-22 DK DK08775278.8T patent/DK2182920T3/en active
- 2008-07-22 EP EP08775278A patent/EP2182920B1/en active Active
- 2008-07-22 GE GEAP200811704A patent/GEP20125525B/en unknown
- 2008-07-22 CN CN2008801012992A patent/CN101784257B/en active Active
- 2008-07-22 PT PT12170235T patent/PT2494955E/en unknown
- 2008-07-22 PL PL08775278T patent/PL2182920T3/en unknown
- 2008-07-22 PT PT87752788T patent/PT2182920E/en unknown
- 2008-07-22 ES ES12170235T patent/ES2531241T3/en active Active
- 2008-07-22 MX MX2010001092A patent/MX2010001092A/en active IP Right Grant
- 2008-07-22 DK DK12170235T patent/DK2494955T3/en active
- 2008-07-22 WO PCT/EP2008/059605 patent/WO2009016069A2/en active Application Filing
- 2008-07-22 SI SI200830897T patent/SI2182920T1/en unknown
- 2008-07-22 SI SI200831393T patent/SI2494955T1/en unknown
- 2008-07-22 SG SG2012055679A patent/SG183659A1/en unknown
- 2008-07-22 AU AU2008281858A patent/AU2008281858B2/en active Active
- 2008-07-22 EA EA201070194A patent/EA016822B1/en not_active IP Right Cessation
- 2008-07-22 ES ES08775278T patent/ES2399569T3/en active Active
- 2008-07-22 UA UAA201000864A patent/UA102376C2/en unknown
- 2008-07-22 PL PL12170235T patent/PL2494955T3/en unknown
- 2008-07-22 BR BRPI0814658-6A2A patent/BRPI0814658A2/en not_active Application Discontinuation
- 2008-07-22 KR KR1020107002151A patent/KR101493370B1/en active IP Right Grant
- 2008-07-22 JP JP2010518618A patent/JP5426548B2/en active Active
- 2008-07-22 US US12/667,694 patent/US10292931B2/en active Active
- 2008-07-22 EP EP12170235.1A patent/EP2494955B1/en active Active
- 2008-07-30 AR ARP080103285A patent/AR068327A1/en not_active Application Discontinuation
-
2010
- 2010-01-06 IL IL203167A patent/IL203167A/en active IP Right Grant
- 2010-05-19 HK HK13102337.3A patent/HK1176280A1/en unknown
- 2010-05-19 HK HK10104941.0A patent/HK1138207A1/en unknown
-
2015
- 2015-03-27 HR HRP20150349TT patent/HRP20150349T1/en unknown
- 2015-04-09 CY CY20151100342T patent/CY1116189T1/en unknown
Non-Patent Citations (1)
Title |
---|
None |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012072665A1 (en) | 2010-11-30 | 2012-06-07 | Pharmaneuroboost N.V. | Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors |
WO2021058810A1 (en) | 2019-09-26 | 2021-04-01 | Angelini S.P.A. | Pediatric trazodone compositions and method of treatment thereof |
CN114615983A (en) * | 2019-09-26 | 2022-06-10 | 安杰利尼股份公司 | Pediatric trazodone compositions and methods of treatment thereof |
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