WO2008132713A1 - Nourishing oil composition for infants and young children - Google Patents
Nourishing oil composition for infants and young children Download PDFInfo
- Publication number
- WO2008132713A1 WO2008132713A1 PCT/IL2007/000522 IL2007000522W WO2008132713A1 WO 2008132713 A1 WO2008132713 A1 WO 2008132713A1 IL 2007000522 W IL2007000522 W IL 2007000522W WO 2008132713 A1 WO2008132713 A1 WO 2008132713A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- acid
- oil composition
- omega
- fatty acid
- young children
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 73
- IPCSVZSSVZVIGE-UHFFFAOYSA-N n-hexadecanoic acid Natural products CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims abstract description 68
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims abstract description 31
- 235000021314 Palmitic acid Nutrition 0.000 claims abstract description 30
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 26
- 229930195729 fatty acid Natural products 0.000 claims abstract description 26
- 239000000194 fatty acid Substances 0.000 claims abstract description 26
- 239000012530 fluid Substances 0.000 claims abstract description 21
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims abstract description 19
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims abstract description 17
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims abstract description 17
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000005642 Oleic acid Substances 0.000 claims abstract description 17
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims abstract description 17
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 14
- 240000008415 Lactuca sativa Species 0.000 claims abstract description 10
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims abstract description 10
- 235000012045 salad Nutrition 0.000 claims abstract description 10
- 230000007704 transition Effects 0.000 claims abstract description 10
- 235000020665 omega-6 fatty acid Nutrition 0.000 claims abstract description 8
- 210000000481 breast Anatomy 0.000 claims abstract description 7
- 229940012843 omega-3 fatty acid Drugs 0.000 claims abstract description 7
- 229940033080 omega-6 fatty acid Drugs 0.000 claims abstract description 7
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims abstract description 6
- 235000021126 varied diet Nutrition 0.000 claims abstract description 4
- 235000013409 condiments Nutrition 0.000 claims abstract description 3
- 150000004665 fatty acids Chemical class 0.000 claims description 24
- 235000006708 antioxidants Nutrition 0.000 claims description 13
- QRYRORQUOLYVBU-VBKZILBWSA-N carnosic acid Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims description 10
- 235000013305 food Nutrition 0.000 claims description 9
- 235000013311 vegetables Nutrition 0.000 claims description 7
- DOUMFZQKYFQNTF-WUTVXBCWSA-N (R)-rosmarinic acid Chemical compound C([C@H](C(=O)O)OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-WUTVXBCWSA-N 0.000 claims description 6
- 150000004671 saturated fatty acids Chemical class 0.000 claims description 4
- 241000195493 Cryptophyta Species 0.000 claims description 3
- ZZAFFYPNLYCDEP-HNNXBMFYSA-N Rosmarinsaeure Natural products OC(=O)[C@H](Cc1cccc(O)c1O)OC(=O)C=Cc2ccc(O)c(O)c2 ZZAFFYPNLYCDEP-HNNXBMFYSA-N 0.000 claims description 3
- DOUMFZQKYFQNTF-MRXNPFEDSA-N rosemarinic acid Natural products C([C@H](C(=O)O)OC(=O)C=CC=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-MRXNPFEDSA-N 0.000 claims description 3
- TVHVQJFBWRLYOD-UHFFFAOYSA-N rosmarinic acid Natural products OC(=O)C(Cc1ccc(O)c(O)c1)OC(=Cc2ccc(O)c(O)c2)C=O TVHVQJFBWRLYOD-UHFFFAOYSA-N 0.000 claims description 3
- 229930003799 tocopherol Natural products 0.000 claims description 3
- 239000011732 tocopherol Substances 0.000 claims description 3
- 235000019149 tocopherols Nutrition 0.000 claims description 3
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 claims description 3
- 239000011719 vitamin A Substances 0.000 claims 2
- 238000010411 cooking Methods 0.000 abstract description 4
- 239000003921 oil Substances 0.000 description 58
- 235000019198 oils Nutrition 0.000 description 58
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 16
- 235000020256 human milk Nutrition 0.000 description 14
- 210000004251 human milk Anatomy 0.000 description 14
- 235000021313 oleic acid Nutrition 0.000 description 13
- 239000008157 edible vegetable oil Substances 0.000 description 9
- 230000008901 benefit Effects 0.000 description 8
- 235000015097 nutrients Nutrition 0.000 description 8
- 239000005639 Lauric acid Substances 0.000 description 7
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 7
- 229960004232 linoleic acid Drugs 0.000 description 7
- 235000013336 milk Nutrition 0.000 description 7
- 239000008267 milk Substances 0.000 description 7
- 210000004080 milk Anatomy 0.000 description 7
- 239000003240 coconut oil Substances 0.000 description 6
- 235000019864 coconut oil Nutrition 0.000 description 6
- 239000000796 flavoring agent Substances 0.000 description 6
- 235000019634 flavors Nutrition 0.000 description 6
- 230000007062 hydrolysis Effects 0.000 description 6
- 238000006460 hydrolysis reaction Methods 0.000 description 6
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 6
- 235000015112 vegetable and seed oil Nutrition 0.000 description 6
- 239000008158 vegetable oil Substances 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 210000004556 brain Anatomy 0.000 description 5
- 235000005911 diet Nutrition 0.000 description 5
- 230000037213 diet Effects 0.000 description 5
- 230000001965 increasing effect Effects 0.000 description 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Natural products CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 4
- 241001072909 Salvia Species 0.000 description 4
- 235000017276 Salvia Nutrition 0.000 description 4
- 235000021355 Stearic acid Nutrition 0.000 description 4
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 4
- 239000003925 fat Substances 0.000 description 4
- 235000019197 fats Nutrition 0.000 description 4
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 230000003078 antioxidant effect Effects 0.000 description 3
- 239000003054 catalyst Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 235000011194 food seasoning agent Nutrition 0.000 description 3
- 235000021588 free fatty acids Nutrition 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 235000020778 linoleic acid Nutrition 0.000 description 3
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 description 3
- 210000000653 nervous system Anatomy 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 230000003647 oxidation Effects 0.000 description 3
- 238000007254 oxidation reaction Methods 0.000 description 3
- 239000003346 palm kernel oil Substances 0.000 description 3
- 235000019865 palm kernel oil Nutrition 0.000 description 3
- 238000007127 saponification reaction Methods 0.000 description 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 241001529742 Rosmarinus Species 0.000 description 2
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 description 2
- 235000019486 Sunflower oil Nutrition 0.000 description 2
- 235000021068 Western diet Nutrition 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 230000002009 allergenic effect Effects 0.000 description 2
- 229910001424 calcium ion Inorganic materials 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 231100000017 mucous membrane irritation Toxicity 0.000 description 2
- 235000021067 refined food Nutrition 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 235000021391 short chain fatty acids Nutrition 0.000 description 2
- 150000004666 short chain fatty acids Chemical class 0.000 description 2
- 235000002316 solid fats Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000002600 sunflower oil Substances 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000024188 Andala Species 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 206010006956 Calcium deficiency Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 240000006240 Linum usitatissimum Species 0.000 description 1
- 235000004431 Linum usitatissimum Nutrition 0.000 description 1
- 235000008452 baby food Nutrition 0.000 description 1
- 239000000828 canola oil Substances 0.000 description 1
- 235000019519 canola oil Nutrition 0.000 description 1
- 201000011529 cardiovascular cancer Diseases 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 235000004426 flaxseed Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 235000021129 infant diet Nutrition 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000009884 interesterification Methods 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000006014 omega-3 oil Substances 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- the invention pertains to the field of infant and baby nutrition.
- composition that combines a lauric acid oil, an oleic acid oil and a linoleic acid oil with a randomized palmitic acid oil.
- Fatty acids especially long chain polyunsaturated fatty acids (PUFA) were found to be of crucial importance in the development of the nervous system, the brain and the vision. They are therefore considered an all important factor in the early nutrition of babies and infants. It has been shown that about 50% of the energy sources in infant food is derived from saturated fatty acids of C 16:0 at position sn 2 and oleic acid — Cl 8:1. DHA, that is the most abundant long chain PUFA in the brain and retina, is thought to be essential for the proper brain and vision development of infants. These components are included in most prior art compositions.
- PUFA long chain polyunsaturated fatty acids
- Vegetable oil applied as an energy source and source of PUFAs in milk replacements, differs from human milk hi several characteristics, inter alia in the presence of 85% of Palmitic acid at position 1 and 3, whereas human milk contains 35% oleic acid and the palmitic acid that consists 25% of human milk fat content is always attached at position 2.
- the presence of Palmitic acid at positions one or three results in saponification in the intestines, causing digestion problems.
- Absorption in the intestines is also significantly higher when the C 16:0 fatty acids are at position 2 as in human milk.
- Vegetable oil milk replacements are therefore apt to cause constipation and extradition in babies and infants. Low absorption also results in calcium deficiency and reduced energy supply (Lucas 1997).
- compositions contain palm kernel oil and/or coconut oil mainly composed of saturated medium chain free fatty acids shorter than 16:0 as a source of energy, having the advantage that they do not undergo saponification with calcium ions.
- These oils are in fact solid fats at room temperature conditions. It is therefore impractical to use the compositions of the prior art as an edible oil for salads etc. In fact, the composition would at least have two phases and would need to be heated before it could be poured onto a salad.
- Short chain fatty acids - acetic acid to capric acid - have threshold values in the range lto 10 P.P.M whereas lauric and myrisitic acids have values of 50 P.P.M. For this reason, using compositions containing lauric oils as an edible oil for a young child wouldn't be practical, especially considering the fact that grownup members of the family may also participate in the same meal.
- Lauric acid may cause mucous membrane irritation and that this fatty acid produces froth when warmed to 100 degrees together with other fatty acids.
- compositions such as those described in JP4287637 are chemically and enzymatically processed to alter the natural composition of the vegetable oil and enable the imitation of human milk properties.
- the vegetable oil fat compositions disclosed in the above mentioned US 5,000,975 also contain a randomized palmitic oil, characterized by having a larger percentage of palmitic acid at position 2 than that found in natural palmitic oil, in order to simulate the larger concentration of palmitic acid at position two that is characteristic of human milk.
- interesterification also called randomization (since it alters the non-random distribution of nature), may be accomplished by heating the fat or oil for a short period of time, usually with a catalyst such as sodium methylate.
- the prior art proposes various milk replacements to be applied where the mother is unable or unwilling to breast feed the infant.
- none of the prior art documents proposes a nourishing edible fluid oil composition for seasoning, baking and light frying to be consumed as an integral part of the infant's gradually diversifying diet during the transition period from bottle or breast feeding.
- a nourishing fluid oil composition for young children and babies to be consumed during the transition period between breast feeding or bottle feeding and a fully varied diet comprising 35% or more oleic acid, less than 10% fatty acid C 16:0 at positions snl or sn3, and 9% or more omega 3, further comprising DHA and antioxidants and optionally comprising palmitic acid sn 2, wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1 :2 to 1 :4.
- the invention proposes a nourishing oil composition that is fluid at room temperature, to be consumed during the transition period between breast or bottle feeding and fully diversified grownup nutrition.
- the oil composition of the invention is intended for use as a condiment in salads and other food products as well as an oil for baking and light frying.
- the inventive composition is a nourishing fluid oil composition for young children and babies to be consumed during the transition period between breast feeding or bottle feeding and a fully varied diet comprising 35% or more of oleic acid, less than 10% fatty acid C16:0 at positions snl or sn3 and 9% or more omega 3, and further comprising DHA, preferably of algae oil, and antioxidants such as tocopherols, Rosmarinic acid or Carnosic acid and optionally comprising palmitic acid sn 2, and wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1:2 (6-12month) to 1:3-1:4 (8-24 months).
- the proposed composition contains different PUFA's and Omega 3 fatty acids necessary for the development of the nervous system, of the brain and of visionary skills such as DHA from algae and ALA from Canola oil or omega 3 extracted from Salvia or linseed, by cold press together with oleic acid as an energy source to which various vitamins and antioxidants are added to further boost the general development and health of the child.
- Salvia oil naturally contains polyphenols with an antioxidant effect that protect the long chain polyunsaturated fatty acids from oxidation.
- antioxidants such as tocopherols, rosmarinic acid and carnosic acid is therefore important for the prevention of oxidation, thus prolonging the shelf lifetime of the inventive composition.
- composition components that are important for the early development of the child such as one or more sources of energy, one or more PUFAs, DHA, ALA, Omega 3, vitamins, antioxidants etc., it is no more necessary at the partial weaning or post weaning stages to closely imitate the composition of human milk.
- compositions of the prior art intended for the early age are prepared with an objective to imitate the fatty acid profile of human milk while using fats derived from diverse vegetal sources, having fatty acid profiles that differ considerably from that of human milk.
- human milk contains about 25% palmitic acid at position 2 and about 35% oleic acid whereas in vegetable sources 85% of the palmitic acid is at position 1 or 3.
- compositions contain palm kern oil and/or coconut oil as a vegetable source of energy and PUFAs. These oils are in fact solid fats at room temperature conditions. It is therefore impractical to use the compositions of the prior art as edible oils for salads etc. In fact, the composition would at least have two phases and would need to be heated before it could be poured onto a salad.
- the inventive composition contains oils that are fluid at room temperature and may be poured as normal household oil. It will be obvious to those versed in the art that a composition containing a high percentage of palm kern oil or coconut oil or both could not be used as an oil to be added to salads due to the fact that triglycerides tend to undergo hydrolysis in the presence of water and catalysts such as enzymes, both found in salad vegetables and other foods. As a result of hydrolysis free fatty acids are released, with a direct bearing on the flavour of the oil. Where the oil contains only palmitic,oleic, linoleic and stearic acids hydrolysis rancidity yields fatty acid products with a taste and smell that are not very different from those of original oil.
- lauric oils such as palm kernel oil and coconut oils release capric and lauric acids, whose flavour threshold that is much lower than that of palmitic acid and stearic acids, the flavour threshold being the minimum concentration in which a pure compound can be perceived by 50% of panel tasters.
- Short chain fatty acids - acetic acid to capric acid - have threshold values in the range lto 10 P.P.M whereas lauric and myrisitic acids have values of 50 P.P.M.
- using compositions containing lauric oils as an edible oil for a young child wouldn't be practical, especially considering the fact that grownup members of the family may also participate in the same meal.
- the inventive composition proposes a solution for the above problem by having a reduced content of palmitic and lauric acid, compliant with the fact that at this transition phase the young child has access to increasingly diversified foods as source of energy. It is desirable to introduce in the compositions according to the invention an increased content of oleic acid that has the advantage of being a monosaturated fatty acid.
- palm kern oil and coconut oil contain lauric acid as a large percentage of the fatty acid molecules attached at positions one two or three, thus differing from human milk that is rich in palmitic acid at position 2.
- the low percentage of Whyley acid in the composition also prevents the effect of froth produced when this fatty acid is warmed to 100 degrees together with other fatty acids, making it possible to use the inventive oil for light frying.
- omega-6 polyunsaturated fatty acids PUFA
- omega-6/omega-3 ratio a very high omega-6/omega-3 ratio
- compositions are chemically processed to alter the natural composition of the vegetable oil and enable the imitation of human milk properties.
- the versatility, availability and affordable price of components such as sunflower oil or soy oil that are the principal sources of omega 6 fatty acids is well known.
- the inventive oil composition thus has the further advantage of being cost saving due to the ratio of 1 :2 to 1 :4 between omega 3 and omega 6 oils.
- inventive oil composition has the advantage that food prepared with this oil composition has a more pleasant taste than the prior art due to the improved organoleptic qualities of sunflower oil.
- a nutrient oil composition recommended for 6 - 12 months
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Pediatric Medicine (AREA)
- Edible Oils And Fats (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Seasonings (AREA)
Abstract
A nourishing fluid oil composition for young children and babies to be consumed during the transition period between breast feeding or bottle feeding and a fully varied diet comprising 35% or more oleic acid, less than 10% fatty acid C16:0 at positions sn1 or sn3, and 9% or more omega 3, further comprising DHA and antioxidants and optionally comprising palmitic acid sn 2, wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1:2 to 1:4. To be used as a condiment in salads or for cooking, baking and light frying.
Description
NOURISHING OIL COMPOSITION FOR INFANTS AND
YOUNG CHILDREN
Technical Field
The invention pertains to the field of infant and baby nutrition.
Background of the Invention
In recent years many kinds of nutrient compositions have been developed with a view to enhancing the supply of necessary fatty acids and their precursors to preterm as well as full term infants.
It is the objective of the prior art nutrient compositions is to imitate the fatty acid profile of human milk while using fats derived from diverse vegetal sources, having different fatty acid profiles.
Thus in US 5,000,975 to Tomarelli a composition is disclosed that combines a lauric acid oil, an oleic acid oil and a linoleic acid oil with a randomized palmitic acid oil.
Fatty acids, especially long chain polyunsaturated fatty acids (PUFA) were found to be of crucial importance in the development of the nervous system, the brain and the vision. They are therefore considered an all important factor in the early nutrition of babies and infants. It has been shown that about 50% of the energy sources in infant food is derived from saturated fatty acids of C 16:0 at position sn 2 and oleic acid — Cl 8:1. DHA, that is the most abundant long chain PUFA in the brain and retina, is thought to be essential for the proper brain and vision development of infants. These components are included in most prior art compositions.
The preparations of the prior art have several disadvantages:
Vegetable oil, applied as an energy source and source of PUFAs in milk replacements, differs from human milk hi several characteristics, inter alia in the presence of 85% of Palmitic acid at position 1 and 3, whereas human milk contains 35% oleic acid and the palmitic acid that consists 25% of human milk fat content is always attached at position 2. The presence of Palmitic acid at positions one or three results in saponification in the intestines, causing digestion problems. Absorption in the intestines is also significantly higher when the C 16:0 fatty acids are at position 2 as in human milk. Vegetable oil milk replacements are therefore apt to cause
constipation and extradition in babies and infants. Low absorption also results in calcium deficiency and reduced energy supply (Lucas 1997).
Many prior art compositions contain palm kernel oil and/or coconut oil mainly composed of saturated medium chain free fatty acids shorter than 16:0 as a source of energy, having the advantage that they do not undergo saponification with calcium ions. These oils are in fact solid fats at room temperature conditions. It is therefore impractical to use the compositions of the prior art as an edible oil for salads etc. In fact, the composition would at least have two phases and would need to be heated before it could be poured onto a salad.
Additionally, Tryglicerids undergo hydrolysis in the presence of water and catalysts such as enzymes, both found in salad vegetables and other foods. As a result of hydrolysis free fatty acids are released, with a direct bearing on the flavour of the oil. Where the oil contains only palmitic,oleic, linoleic and stearic acids hydrolysis rancidity yields fatty acid products with a taste and smell that are not very different from those of original oil. However lauric oils such as palm kernel oil and coconut oils release capric and lauric acids, whose flavour threshold that is much lower than that of palmitic acid and stearic acids, the flavour threshold being the minimum concentration in which a pure compound can be perceived by 50% of panel tasters. Short chain fatty acids - acetic acid to capric acid - have threshold values in the range lto 10 P.P.M whereas lauric and myrisitic acids have values of 50 P.P.M. For this reason, using compositions containing lauric oils as an edible oil for a young child wouldn't be practical, especially considering the fact that grownup members of the family may also participate in the same meal.
It is also known from the prior art that Lauric acid may cause mucous membrane irritation and that this fatty acid produces froth when warmed to 100 degrees together with other fatty acids.
It is known from the prior art that no more than 10% of palmitic acid in positions other than 2 should be used in milk replacement formulas.
Other prior art compositions such as those described in JP4287637 are chemically and enzymatically processed to alter the natural composition of the vegetable oil and enable the imitation of human milk properties.
The vegetable oil fat compositions disclosed in the above mentioned US 5,000,975 also contain a randomized palmitic oil, characterized by having a larger percentage of palmitic acid at position 2 than that found in natural palmitic oil, in order to simulate the larger concentration of palmitic acid at position two that is characteristic of human milk. As described in US 5,000,975, interesterification, also called randomization (since it alters the non-random distribution of nature), may be accomplished by heating the fat or oil for a short period of time, usually with a catalyst such as sodium methylate. Though it is well known from the prior art that raising the percentage of palmitic acid at position two facilitates absorption of this important fatty acid energy source, recent tendencies in research and consumer preference indicate strongly against the consumption of processed food and it is considered increasingly preferable to use natural components and compositions, especially where young children are concerned.
The prior art proposes various milk replacements to be applied where the mother is unable or unwilling to breast feed the infant. However none of the prior art documents proposes a nourishing edible fluid oil composition for seasoning, baking and light frying to be consumed as an integral part of the infant's gradually diversifying diet during the transition period from bottle or breast feeding.
It is therefore desirable to develop a nourishing edible oil composition for young children and babies to be consumed during the transition period from a full milk diet to diversified grownup diet.
It is also desirable to develop a nourishing edible oil composition for young children and babies that is fluid at room temperature.
It is desirable to overcome the drawbacks of the prior art by controlling the proportion of different fatty acids through determining the percentage of oil components rather than using artificial processing such as trans esterification by chemical means.
It is further desirable to develop a nourishing edible oil composition for young children and babies that contains the fatty acids necessary for the development of the nervous system, of the brain and of visionary skills, while having a reduced content of palmitic and lauric acid, compliant with the fact that at this transition phase the young child has access to increasingly diversified foods as source of energy.
It is desirable to introduce in these compositions an increased content of oleic acid that has the advantage of being a monosaturated fatty acid.
It is further desirable to develop a nourishing edible oil composition for young children and babies with a pleasant taste such that it may be used for the cooking and conditioning of food during the transition period from a full milk diet to a diversified grownup diet while it may also be consumed by grownups.
Summary of the invention
A nourishing fluid oil composition for young children and babies to be consumed during the transition period between breast feeding or bottle feeding and a fully varied diet comprising 35% or more oleic acid, less than 10% fatty acid C 16:0 at positions snl or sn3, and 9% or more omega 3, further comprising DHA and antioxidants and optionally comprising palmitic acid sn 2, wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1 :2 to 1 :4.
Detailed Description of the Invention
The invention will be described herein below in detail and in accordance with examples that are to be regarded as non limiting preferred embodiments. It will be understood that many other ways and means of performing the inventive method are envisaged without exceeding the scope of the invention as defined and claimed in the claims.
In accordance with one aspect of the invention, the invention proposes a nourishing oil composition that is fluid at room temperature, to be consumed during the transition period between breast or bottle feeding and fully diversified grownup nutrition. The oil composition of the invention is intended for use as a condiment in salads and other food products as well as an oil for baking and light frying.
In accordance with a second aspect of the invention, the inventive composition is a nourishing fluid oil composition for young children and babies to be consumed during the transition period between breast feeding or bottle feeding and a fully varied diet comprising 35% or more of oleic acid, less than 10% fatty acid C16:0 at positions snl or sn3 and 9% or more omega 3, and further comprising DHA, preferably of algae oil, and antioxidants such as tocopherols, Rosmarinic acid or Carnosic acid and optionally comprising palmitic acid sn 2, and wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1:2 (6-12month) to 1:3-1:4 (8-24 months).
The proposed composition contains different PUFA's and Omega 3 fatty acids necessary for the development of the nervous system, of the brain and of visionary skills such as DHA from algae and ALA from Canola oil or omega 3 extracted from Salvia or linseed, by cold press together with oleic acid as an energy source to which various vitamins and antioxidants are added to further boost the general development and health of the child. Salvia oil naturally contains polyphenols with an antioxidant effect that protect the long chain polyunsaturated fatty acids from oxidation.
It is well known from the prior art that fatty acids of the Omega 3 group are relatively sensitive to oxidation. The inclusion of antioxidants such as tocopherols, rosmarinic acid and carnosic acid is therefore important for the prevention of oxidation, thus prolonging the shelf lifetime of the inventive composition.
It will be understood by those versed in the art that while it is important to include in the proposed composition components that are important for the early development of the child such as one or more sources of energy, one or more PUFAs, DHA, ALA, Omega 3, vitamins, antioxidants etc., it is no more necessary at the partial weaning or post weaning stages to closely imitate the composition of human milk.
It will be further understood that in the early months after weaning enzyme activity of DHA production from alpha linoleic acid (ALA) is still quite low. For this reason DHA is included in the inventive composition m addition to ALA.
Many nutrient compositions of the prior art intended for the early age are prepared with an objective to imitate the fatty acid profile of human milk while using fats derived from diverse vegetal sources, having fatty acid profiles that differ considerably from that of human milk. Thus human milk contains about 25% palmitic acid at position 2 and about 35% oleic acid whereas in vegetable sources 85% of the palmitic acid is at position 1 or 3.
Many of the prior art compositions contain palm kern oil and/or coconut oil as a vegetable source of energy and PUFAs. These oils are in fact solid fats at room temperature conditions. It is therefore impractical to use the compositions of the prior art as edible oils for salads etc. In fact, the composition would at least have two phases and would need to be heated before it could be poured onto a salad.
Thus it is an important advantage of the inventive composition that it contains oils that are fluid at room temperature and may be poured as normal household oil.
It will be obvious to those versed in the art that a composition containing a high percentage of palm kern oil or coconut oil or both could not be used as an oil to be added to salads due to the fact that triglycerides tend to undergo hydrolysis in the presence of water and catalysts such as enzymes, both found in salad vegetables and other foods. As a result of hydrolysis free fatty acids are released, with a direct bearing on the flavour of the oil. Where the oil contains only palmitic,oleic, linoleic and stearic acids hydrolysis rancidity yields fatty acid products with a taste and smell that are not very different from those of original oil. However lauric oils such as palm kernel oil and coconut oils release capric and lauric acids, whose flavour threshold that is much lower than that of palmitic acid and stearic acids, the flavour threshold being the minimum concentration in which a pure compound can be perceived by 50% of panel tasters. Short chain fatty acids - acetic acid to capric acid - have threshold values in the range lto 10 P.P.M whereas lauric and myrisitic acids have values of 50 P.P.M. For this reason, using compositions containing lauric oils as an edible oil for a young child wouldn't be practical, especially considering the fact that grownup members of the family may also participate in the same meal.
The inventive composition proposes a solution for the above problem by having a reduced content of palmitic and lauric acid, compliant with the fact that at this transition phase the young child has access to increasingly diversified foods as source of energy. It is desirable to introduce in the compositions according to the invention an increased content of oleic acid that has the advantage of being a monosaturated fatty acid.
It is known from the prior art that both palm kern oil and coconut oil contain lauric acid as a large percentage of the fatty acid molecules attached at positions one two or three, thus differing from human milk that is rich in palmitic acid at position 2.
It is also well known that absorption in the intestines is significantly higher when the palmitic acid C 16:0 is at position 2 as in human milk. Vegetable oil milk replacements are therefore apt to cause constipation and extradition in babies and infants. The low percentage of palmitic and lauric acid and their replacement by the mono saturated fatty acid oleic acid as energy source in the inventive composition helps to overcome these problems by increasing absorption as well as preventing mucous membrane irritation caused by Lauric acid.
It is important to note that consumption of the inventive composition by women is advantageous as the saponification process characteristic of saturated PUF A's above 14C such as Palmitic acid absorbs the Calcium ions that are vital for this section of the population.
The low percentage of Laurie acid in the composition also prevents the effect of froth produced when this fatty acid is warmed to 100 degrees together with other fatty acids, making it possible to use the inventive oil for light frying.
Several research findings have shown that excessive amounts of omega-6 polyunsaturated fatty acids (PUFA) and a very high omega-6/omega-3 ratio, as is found in today's Western diets, promote the pathogenesis of many diseases, including cardiovascular disease, cancer, and inflammatory and autoimmune diseases, whereas increased levels of omega-3 PUFA (a low omega-6/omega-3 ratio) exert suppressive effects. (Simopoulos AP PubMed October 2002).
It is therefore one of the advantages of the nutrient oil of the present invention that a ratio of 1:2 to 1:4 of omega 3:omega 6 is observed, that is a considerable improvement compared to the ratio of 1 :24 in western diet.
Many of the prior art compositions are chemically processed to alter the natural composition of the vegetable oil and enable the imitation of human milk properties.
Recent tendencies in research and consumer preference indicate strongly against the consumption of processed food and it is considered increasingly preferable to use natural components and compositions, especially where young children are concerned.
It is yet another advantage of the oil composition of the present invention that only natural food products are used and components are not subjected to artificial processing such as chemical randomization to increase the percentage of palmitic acid at position 2. hi accordance with the inventive composition the percentage of position 2 palmitic acid is controlled mainly through the selection of the components of the oil composition.
The versatility, availability and affordable price of components such as sunflower oil or soy oil that are the principal sources of omega 6 fatty acids is well known.
The inventive oil composition thus has the further advantage of being cost saving due to the ratio of 1 :2 to 1 :4 between omega 3 and omega 6 oils.
Finally the inventive oil composition has the advantage that food prepared with this oil composition has a more pleasant taste than the prior art due to the improved organoleptic qualities of sunflower oil.
The following are examples of oil compositions in accordance with the invention, not intended to limit the scope of the invention.
Example I
A nutrient oil composition recommended for 6 - 12 months
The following table describes the components proposed for an example of a bottled oil suitable for seasoning, cooking, baking and very light frying in accordance with the invention that is recommended for 6 - 12 months wherein the contribution of each ingredient to the final percentage of a nutrient is shown (percentage by volume, except where otherwise indicated):
ALA oil of Salvia oil or Linoleic oil source free of Cyanidic acid and free of traces of allergenics
** Natural source antioxidant extracted from Rosemary
***20% of RDI in two spoonfuls of oil
It will be understood that while use of the nourishing oil composition of example I is more recommended for the early age of 6-12 months when an increased supply of palmitic acid at position sn-2 is necessary, this composition may be applied for a more advanced age and the indication of 6-12 months is not intended to be limiting to the invention.
Example II
A nutrient oil composition recommended for 8-24 months
The following table describes the components proposed for an example of a bottled oil suitable for seasoning, cooking, baking and very baking and light frying in accordance with the invention that is recommended for 8-24 months, wherein the contribution of each component to the final percentage of a nutrient is shown (percentage by volume, except where otherwise indicated):
* ALA oil of Salvia oil or Linoleic oil source free of Cyanidic acid and free of traces of allergenics
** Natural source antioxidant extracted from Rosemary ***20% of RDI in two spoonfuls of oil
It will be noted that the position sn-2 palmitic acid content in example II is lower than in example I and to prevent an undesirably high content of palmitic acid at positions sn 1, 3 an added amount of oleic acid is included.
It will be understood by those versed in the art that while this composition is recommended as an edible oil for consumption between 8 months to 2 years, there is no precise limitation to the actual start of use that also depends on the ambit of variation in the infant's diet. It will be further understood that the recommended period is not to be regarded as restrictive to the invention and actual use of the composition of example 2 may continue beyond the age of 24 months.
Claims
1. A nourishing fluid oil composition for young children and babies to be consumed during the transition period between breast feeding or bottle feeding and a fully varied diet comprising 35% or more oleic acid, less than 10% fatty acid C 16:0 at positions snl or sn3, and 9% or more omega 3, further comprising DHA and antioxidants and optionally comprising palmitic acid sn 2, wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1 :2 to 1:4.
2. A nourishing fluid oil composition for young children and babies according to claim 1 wherein the said antioxidants are of vegetable source.
3. A nourishing fluid oil composition for young children and babies according to claim 1 wherein the said antioxidants are selected from the group of tocopherols.
4. A nourishing fluid oil composition for young children and babies according to claim 1 wherein the said antioxidants are Rosmarinic acid or Carnosic acid.
5. A nourishing fluid oil composition for young children and babies according to claim 1 wherein the said DHA is of vegetable source.
6. A nourishing fluid oil composition for young children and babies according to claim 1 wherein the said vegetable source is algae oil.
7. A nourishing fluid oil composition for young children and babies according to claim 1 wherein the said DHA is offish oil.
8. A nourishing fluid oil composition for young children and babies according to claim 1 to be used as a condiment in salads and other foods.
9. A nourishing fluid oil composition for young children and babies according to claim 1 to be used for baking.
10. A nourishing fluid oil composition for young children and babies according to claim 1 to be used for light frying.
12
11. A nourishing fluid oil composition that is recommended for use between 6-12 months, comprising 35% or more oleic acid, less than 10% fatty acid C 16:0 at positions snl or sn3, 9% or more omega 3, further comprising DHA and antioxidants, and optionally comprising palmitic acid sn 2, wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1 :2.
12. A nourishing fluid oil composition that is recommended for use between 8-24 months, comprising 35% or more oleic acid, less than 10% fatty acid C 16:0 at positions snl or sn3, 9% or more omega 3, further comprising DHA and antioxidants and optionally comprising palmitic acid sn 2, wherein the ratio of omega 3 fatty acid to omega 6 fatty acid is between 1 :3-l :4.
13. A nourishing fluid oil composition that is recommended for use between 6-12 months, comprising up to 63% oleic acid, saturated fatty acid sn 1,3 6-6.5%; palmitic acid sn2 2.3-2.6%; DHA 0.42-0.47%; ALA 9.12%^ carnosic acid 0.1- 0.2%; Vitamins A5C5E 20% of RDI in 2 spoonfuls.
14. A nourishing fluid oil composition that is recommended for use between 8-24 months, comprising oleic acid 55-58%; saturated fatty acid sn 1,3 4-4.5%; palmitic acid sn2 0.5-0.9% DHA 0.42-0.2-0.6%; ALA 8.00 -11.00%; carnosic acid 0.1-0.2%; Vitamins A5C5E 20% of RDI in 2 spoonfuls.
13
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
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JP2010504997A JP2010524493A (en) | 2007-04-29 | 2007-04-29 | Oil composition for nutrition supply for infants and toddlers |
EP07736262A EP2154984A1 (en) | 2007-04-29 | 2007-04-29 | Nourishing oil composition for infants and young children |
PCT/IL2007/000522 WO2008132713A1 (en) | 2007-04-29 | 2007-04-29 | Nourishing oil composition for infants and young children |
US12/597,949 US20110274790A1 (en) | 2007-04-29 | 2007-04-29 | Nourishing oil composition for infants and young children |
IL201809A IL201809A0 (en) | 2007-04-29 | 2009-10-29 | Nourishing oil composition for infants and young children |
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PCT/IL2007/000522 WO2008132713A1 (en) | 2007-04-29 | 2007-04-29 | Nourishing oil composition for infants and young children |
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WO2008132713A1 true WO2008132713A1 (en) | 2008-11-06 |
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PCT/IL2007/000522 WO2008132713A1 (en) | 2007-04-29 | 2007-04-29 | Nourishing oil composition for infants and young children |
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US (1) | US20110274790A1 (en) |
EP (1) | EP2154984A1 (en) |
JP (1) | JP2010524493A (en) |
WO (1) | WO2008132713A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8168611B1 (en) | 2011-09-29 | 2012-05-01 | Chemo S.A. France | Compositions, kits and methods for nutrition supplementation |
US8183227B1 (en) | 2011-07-07 | 2012-05-22 | Chemo S. A. France | Compositions, kits and methods for nutrition supplementation |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110200084A (en) * | 2019-06-05 | 2019-09-06 | 海南思香源食品有限公司 | A kind of children's ready-mixed oil with functions of loosening bowel relieving constipation |
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- 2007-04-29 EP EP07736262A patent/EP2154984A1/en not_active Withdrawn
- 2007-04-29 WO PCT/IL2007/000522 patent/WO2008132713A1/en active Application Filing
- 2007-04-29 JP JP2010504997A patent/JP2010524493A/en active Pending
- 2007-04-29 US US12/597,949 patent/US20110274790A1/en not_active Abandoned
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US8183227B1 (en) | 2011-07-07 | 2012-05-22 | Chemo S. A. France | Compositions, kits and methods for nutrition supplementation |
US8168611B1 (en) | 2011-09-29 | 2012-05-01 | Chemo S.A. France | Compositions, kits and methods for nutrition supplementation |
US8545896B2 (en) | 2011-09-29 | 2013-10-01 | Chemo S. A. France | Compositions, kits and methods for nutrition supplementation |
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EP2154984A1 (en) | 2010-02-24 |
US20110274790A1 (en) | 2011-11-10 |
JP2010524493A (en) | 2010-07-22 |
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