WO2008059197A3 - Topical composition comprising an anti- inflammatory steroid and a non-steroidal anti -inflammatory drug - Google Patents

Topical composition comprising an anti- inflammatory steroid and a non-steroidal anti -inflammatory drug Download PDF

Info

Publication number
WO2008059197A3
WO2008059197A3 PCT/GB2007/004042 GB2007004042W WO2008059197A3 WO 2008059197 A3 WO2008059197 A3 WO 2008059197A3 GB 2007004042 W GB2007004042 W GB 2007004042W WO 2008059197 A3 WO2008059197 A3 WO 2008059197A3
Authority
WO
WIPO (PCT)
Prior art keywords
inflammatory
topical composition
steroid
steroidal anti
medicament
Prior art date
Application number
PCT/GB2007/004042
Other languages
French (fr)
Other versions
WO2008059197A2 (en
Inventor
Sacha Simon
Original Assignee
Providence Capital Man
Sacha Simon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Providence Capital Man, Sacha Simon filed Critical Providence Capital Man
Publication of WO2008059197A2 publication Critical patent/WO2008059197A2/en
Publication of WO2008059197A3 publication Critical patent/WO2008059197A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Abstract

Use of an anti-inflammatory steroid and a non-steroidal anti-inflammatory drug in the manufacture of a medicament for topical application to a joint of a patient. The medicament may be for treating pain and inflammation at said joint and may be for treating inflammatory arthritis, osteoarthritis or rheumatoid arthritis at said joint. The medicament may be in the form of a transdermal patch.
PCT/GB2007/004042 2006-11-17 2007-10-24 Topical composition comprising an anti- inflammatory steroid and a non-steroidal anti -inflammatory drug WO2008059197A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0622920.7A GB0622920D0 (en) 2006-11-17 2006-11-17 Topical treatment
GB0622920.7 2006-11-17

Publications (2)

Publication Number Publication Date
WO2008059197A2 WO2008059197A2 (en) 2008-05-22
WO2008059197A3 true WO2008059197A3 (en) 2008-07-17

Family

ID=37605447

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/004042 WO2008059197A2 (en) 2006-11-17 2007-10-24 Topical composition comprising an anti- inflammatory steroid and a non-steroidal anti -inflammatory drug

Country Status (2)

Country Link
GB (1) GB0622920D0 (en)
WO (1) WO2008059197A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0915319D0 (en) * 2009-09-03 2009-10-07 Sharma Anant Combination medicament

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US5741510A (en) * 1994-03-30 1998-04-21 Lectec Corporation Adhesive patch for applying analgesic medication to the skin
US6193996B1 (en) * 1998-04-02 2001-02-27 3M Innovative Properties Company Device for the transdermal delivery of diclofenac
US6335034B1 (en) * 1995-09-29 2002-01-01 L.A.M. Pharmaceutical Corporation Topical drug preparations
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
US20050276842A1 (en) * 2004-06-07 2005-12-15 Zars, Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US20060223788A1 (en) * 2005-03-29 2006-10-05 Cathcart Clifton H Analgesic composition for topical use

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US5741510A (en) * 1994-03-30 1998-04-21 Lectec Corporation Adhesive patch for applying analgesic medication to the skin
US6335034B1 (en) * 1995-09-29 2002-01-01 L.A.M. Pharmaceutical Corporation Topical drug preparations
US6193996B1 (en) * 1998-04-02 2001-02-27 3M Innovative Properties Company Device for the transdermal delivery of diclofenac
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
US20050276842A1 (en) * 2004-06-07 2005-12-15 Zars, Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US20060223788A1 (en) * 2005-03-29 2006-10-05 Cathcart Clifton H Analgesic composition for topical use

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BUCCI F A ET AL: "Comparison of ketorolac 0.5%, ketorolac 0.4%, and diclofenac 0.1% on Aqueous Flare Following Cataract Surgery", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, OPHTHALMOLOGY, HAGERSTOWN, MD, vol. 46, no. Suppl. S, 1 January 2005 (2005-01-01), pages 789, XP008091674, ISSN: 0146-0404 *
LEWIS A J: "THE LOCAL ANTI-INFLAMMATORY ACTIVITY OF RIMEXOLONE (ORG 6216) IN FIBRIN-INDUCED MONOARTICULAR ARTHRITIS AND ADJUVANT-INDUCED ARTHRITIS", AGENTS AND ACTIONS, BIRKHAEUSER VERLAG, BASEL, CH, vol. 10, no. 3, 1 January 1980 (1980-01-01), pages 258 - 265, XP009008537, ISSN: 0065-4299 *
MATTEUCCI PAOLA ET AL: "Topical prophylaxis of conjunctivitis induced by high-dose cytosine arabinoside", HAEMATOLOGICA, FONDAZIONE FERRATA STORTI, ROME, IT, vol. 91, no. 2, 1 February 2006 (2006-02-01), pages 255 - 257, XP008091676, ISSN: 0390-6078 *
ROBECCHI A ET AL: "Combination of prednisooe and indomethadn in the treatment of rheumatoid arthritis", REUMATISMO, LONGANESI, MILAN, IT, vol. 18, no. 6, 1 January 1964 (1964-01-01), pages 388 - 392, XP008091663, ISSN: 0048-7449 *

Also Published As

Publication number Publication date
GB0622920D0 (en) 2006-12-27
WO2008059197A2 (en) 2008-05-22

Similar Documents

Publication Publication Date Title
WO2009129149A3 (en) Drug depots having different release profiles for reducing, preventing or treating pain and inflammation
WO2011016881A3 (en) An implantable drug depot having a reversible phase transition material for treatment of pain and/or inflammation
WO2009129147A3 (en) Analgesic and anti-inflammatory compositions and methods for reducing, preventing or treating pain and inflammation
WO2008157103A3 (en) Modified release solid or semi-solid dosage forms
IL194184A0 (en) Formulations of low dose non-steroidal anti-inflammatory drugs and beta-cyclodextrin
WO2010011526A3 (en) Drug depots having one or more anchoring members
WO2008089307A3 (en) Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer
WO2007093183A3 (en) Use of a compound that enhances gabaa-ergic neurotransmission for the treatment of inflammatory diseases
WO2010070675A8 (en) Topical formulation(s) for the treatment of inflammation, skin and mucosal disorders and other diseases thereof
EP2318033B8 (en) Compositions for the treatment of pain and/or inflammation
WO2006100213A8 (en) Composition comprising a combined thromboxane receptor antagonist and thromboxane synthase inhibitor and a cox-2 inhibitor
WO2009063378A3 (en) Olive oil formulation for pain relief
WO2007112453A3 (en) Methods amd compositions for treating conditions
WO2008012796A3 (en) Pharmaceutical compositions comprising ccl2 and use of same for the treatment of inflammation
WO2007100561A3 (en) Use of dha and ara in the preparation of a composition for preventing or treating obesity
WO2012019188A3 (en) Methods and compositions for the inhibition of fructokinase
WO2011074015A3 (en) Composition of pharmaceutical product to treat sexual dysfunction
EP1844779A3 (en) Tergurid/protergurid for treating chronic pain (e.g. migraine)
WO2009012472A3 (en) Methods and compositions for treating conditions
WO2008059197A3 (en) Topical composition comprising an anti- inflammatory steroid and a non-steroidal anti -inflammatory drug
MX2010004513A (en) A standardized plant extract, process for obtaining the same and uses thereof.
ATE505477T1 (en) AMORPHOUS FORM OF (11BETA,16ALPHA)-9-FLUORO-11-
WO2010007494A3 (en) New composition for the treatment of ecchymotic pigmentations
WO2008084171A3 (en) Use of nepafenac or derivatives thereof for treating dermatological disorders linked with a keratinisation disorder that may include an inflammatory immuno-allergic component
WO2007112968A3 (en) Anti-inflammatory polymer

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07824290

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07824290

Country of ref document: EP

Kind code of ref document: A2