WO2008053357A3 - Methods, systems and computer program products for determining treatment response biomarkers - Google Patents
Methods, systems and computer program products for determining treatment response biomarkers Download PDFInfo
- Publication number
- WO2008053357A3 WO2008053357A3 PCT/IB2007/004165 IB2007004165W WO2008053357A3 WO 2008053357 A3 WO2008053357 A3 WO 2008053357A3 IB 2007004165 W IB2007004165 W IB 2007004165W WO 2008053357 A3 WO2008053357 A3 WO 2008053357A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- systems
- computer program
- program products
- treatment response
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Abstract
The invention relates to methods for the identification of biomarkers suitable for determining patient treatment response as well as systems and computer program products of use in such methods.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07859230A EP2078098A2 (en) | 2006-11-01 | 2007-11-01 | Methods, systems and computer program products for determining treatment response biomarkers |
US12/312,269 US20090264302A1 (en) | 2006-11-01 | 2007-11-01 | Methods, systems and computer program products for determining treatment response biomarkers |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06123310 | 2006-11-01 | ||
EP06123310.2 | 2006-11-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008053357A2 WO2008053357A2 (en) | 2008-05-08 |
WO2008053357A3 true WO2008053357A3 (en) | 2008-07-31 |
Family
ID=39332507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2007/004165 WO2008053357A2 (en) | 2006-11-01 | 2007-11-01 | Methods, systems and computer program products for determining treatment response biomarkers |
Country Status (3)
Country | Link |
---|---|
US (1) | US20090264302A1 (en) |
EP (1) | EP2078098A2 (en) |
WO (1) | WO2008053357A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018191806A1 (en) | 2017-04-18 | 2018-10-25 | Nortek Air Solutions Canada, Inc. | Desiccant enhanced evaporative cooling systems and methods |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002040710A2 (en) * | 2000-11-14 | 2002-05-23 | Epigenomics Ag | Method for detecting methylation states for a toxicological diagnostic |
WO2003087774A2 (en) * | 2002-04-12 | 2003-10-23 | Curators Of The University Of Missouri | Ecist microarrays for dual screening of dna hypermethylation and gene silencing |
US20040029117A1 (en) * | 2001-03-01 | 2004-02-12 | Alexander Olek | Methods, systems and computer program products for determining the biological effect and/or activity of drugs, chemical substances and/or pharmaceutical compositions based on their effect on the methylation status of the DNA |
WO2006004597A2 (en) * | 2004-06-01 | 2006-01-12 | University Of Southern California | Association of breast cancer dna methylation profiles with hormone receptor status and response to tamoxifen |
US20060024684A1 (en) * | 2002-10-01 | 2006-02-02 | Epigenomics Ag | Prognostic markers for prediction of treatment response and/or survival of breast cell proliferative disorder patients |
WO2007085497A2 (en) * | 2006-01-30 | 2007-08-02 | Epigenomics Ag | Markers for the prediction of outcome of anthracycline treatment |
-
2007
- 2007-11-01 EP EP07859230A patent/EP2078098A2/en not_active Withdrawn
- 2007-11-01 WO PCT/IB2007/004165 patent/WO2008053357A2/en active Application Filing
- 2007-11-01 US US12/312,269 patent/US20090264302A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002040710A2 (en) * | 2000-11-14 | 2002-05-23 | Epigenomics Ag | Method for detecting methylation states for a toxicological diagnostic |
US20040029117A1 (en) * | 2001-03-01 | 2004-02-12 | Alexander Olek | Methods, systems and computer program products for determining the biological effect and/or activity of drugs, chemical substances and/or pharmaceutical compositions based on their effect on the methylation status of the DNA |
WO2003087774A2 (en) * | 2002-04-12 | 2003-10-23 | Curators Of The University Of Missouri | Ecist microarrays for dual screening of dna hypermethylation and gene silencing |
US20060024684A1 (en) * | 2002-10-01 | 2006-02-02 | Epigenomics Ag | Prognostic markers for prediction of treatment response and/or survival of breast cell proliferative disorder patients |
WO2006004597A2 (en) * | 2004-06-01 | 2006-01-12 | University Of Southern California | Association of breast cancer dna methylation profiles with hormone receptor status and response to tamoxifen |
WO2007085497A2 (en) * | 2006-01-30 | 2007-08-02 | Epigenomics Ag | Markers for the prediction of outcome of anthracycline treatment |
Non-Patent Citations (6)
Title |
---|
DATABASE BIOSIS BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; March 2003 (2003-03-01), NEWBERRY S ET AL.: "Methylation analysis of the BRCA1 promoter in human breast cancer cell lines", XP002481098 * |
ESTELLER M ET AL.: "Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents", THE NEW ENGLAND JOURNALOF MEDICINE, vol. 343, 2000, pages 1350 - 1354, XP002481097 * |
FUKAI K ET AL.: "Hepatocyte growth factor activator inhibitor 2/placental Bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma", CANCER RESEARCH, vol. 63, 2003, pages 8674 - 8679, XP002481095 * |
GALM OLIVER ET AL: "Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies", INTERNATIONAL JOURNAL OF HEMATOLOGY, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 80, no. 2, 1 August 2004 (2004-08-01), pages 120 - 127, XP008091275, ISSN: 0925-5710 * |
JEONG K-S AND LEE S: "Estmating the total mouse DNA methylation according to the B1 repetitive elements", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 335, 2005, pages 1211 - 1216, XP002481096 * |
NEWBERRY S T ET AL.: "Methylation analysis of the BRCA1 promoter in human breast cancer cell lines", FASEB JOURNAL, vol. 17, no. 4-5, March 2003 (2003-03-01), pages A673 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008053357A2 (en) | 2008-05-08 |
US20090264302A1 (en) | 2009-10-22 |
EP2078098A2 (en) | 2009-07-15 |
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