WO2008047239A3 - Stable aerosol pharmaceutical formulations - Google Patents

Stable aerosol pharmaceutical formulations Download PDF

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Publication number
WO2008047239A3
WO2008047239A3 PCT/IB2007/004101 IB2007004101W WO2008047239A3 WO 2008047239 A3 WO2008047239 A3 WO 2008047239A3 IB 2007004101 W IB2007004101 W IB 2007004101W WO 2008047239 A3 WO2008047239 A3 WO 2008047239A3
Authority
WO
WIPO (PCT)
Prior art keywords
stable aerosol
aerosol pharmaceutical
pharmaceutical formulations
pharmaceutical formulation
stable
Prior art date
Application number
PCT/IB2007/004101
Other languages
French (fr)
Other versions
WO2008047239A2 (en
Inventor
Rajesh Sawant
Sunil Parab
Original Assignee
Medispray Lab Pvt Ltd
Rajesh Sawant
Sunil Parab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/533,857 external-priority patent/US20070286814A1/en
Application filed by Medispray Lab Pvt Ltd, Rajesh Sawant, Sunil Parab filed Critical Medispray Lab Pvt Ltd
Publication of WO2008047239A2 publication Critical patent/WO2008047239A2/en
Publication of WO2008047239A3 publication Critical patent/WO2008047239A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Abstract

The present invention provides a stable aerosol pharmaceutical formulation of a beta-agonist, an anticholinergic, or a combination thereof in combination with a cosolvent and optionally a surfactant. The invention also provides a method of making the stable aerosol pharmaceutical formulation and methods of treating bronchoconstriction, asthma and related conditions with the stable aerosol pharmaceutical formulation of the present invention.
PCT/IB2007/004101 2006-09-21 2007-09-21 Stable aerosol pharmaceutical formulations WO2008047239A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/533,857 2006-09-21
US11/533,857 US20070286814A1 (en) 2006-06-12 2006-09-21 Stable aerosol pharmaceutical formulations

Publications (2)

Publication Number Publication Date
WO2008047239A2 WO2008047239A2 (en) 2008-04-24
WO2008047239A3 true WO2008047239A3 (en) 2009-04-23

Family

ID=39314414

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/004101 WO2008047239A2 (en) 2006-09-21 2007-09-21 Stable aerosol pharmaceutical formulations

Country Status (1)

Country Link
WO (1) WO2008047239A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455028B1 (en) * 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
US20040184994A1 (en) * 2003-03-20 2004-09-23 Boehringer Ingelheim Pharmaceuticals, Inc. Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants
US20060002863A1 (en) * 2004-07-02 2006-01-05 Boehringer Ingelheim International Gmbh Aerosol suspension formulations containing TG 227 ea or TG 134 a as propellant

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455028B1 (en) * 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
US20040184994A1 (en) * 2003-03-20 2004-09-23 Boehringer Ingelheim Pharmaceuticals, Inc. Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants
US20060002863A1 (en) * 2004-07-02 2006-01-05 Boehringer Ingelheim International Gmbh Aerosol suspension formulations containing TG 227 ea or TG 134 a as propellant

Also Published As

Publication number Publication date
WO2008047239A2 (en) 2008-04-24

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