WO2008003605A1 - Process for the preparation of sterically hindered nitroxyl ethers - Google Patents
Process for the preparation of sterically hindered nitroxyl ethers Download PDFInfo
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- WO2008003605A1 WO2008003605A1 PCT/EP2007/056301 EP2007056301W WO2008003605A1 WO 2008003605 A1 WO2008003605 A1 WO 2008003605A1 EP 2007056301 W EP2007056301 W EP 2007056301W WO 2008003605 A1 WO2008003605 A1 WO 2008003605A1
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- Prior art keywords
- formula
- compound
- yield
- hydroperoxide
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- 0 CC(C)(CC(CC1(C)C)=O)N1O* Chemical compound CC(C)(CC(CC1(C)C)=O)N1O* 0.000 description 1
- MAMANMWYRUNPMM-UHFFFAOYSA-N CCCCNC(CC1(C)C)CC(C)(C)N1OC1CCCCC1 Chemical compound CCCCNC(CC1(C)C)CC(C)(C)N1OC1CCCCC1 MAMANMWYRUNPMM-UHFFFAOYSA-N 0.000 description 1
- RXFCIXRFAJRBSG-UHFFFAOYSA-N NCCCNCCNCCCN Chemical compound NCCCNCCNCCCN RXFCIXRFAJRBSG-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Definitions
- the present invention relates to a novel process for the preparation of specific sterically hindered nitroxyl ethers from their corresponding sterically hindered nitroxyl radicals by reacting the nitroxyl radicals with an aldehyde and a hydroperoxide.
- This nitroxyl ether formation may be carried out from different starting nitroxyl radicals, which are subsequently further reacted to the desired compounds.
- the compounds prepared by this process are effective as stabilizers for polymers against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers.
- sterically hindered nitroxyl radical used in the present invention is a synonym for the term sterically hindered nitroxide, which is also frequently used in the literature. Consequently the term sterically hindered nitroxyl ether used in the present invention is used as a synonym for sterically hindered nitroxide ether or sterically hindered alkoxyamine.
- WO 01/92228 describes a process for the preparation of nitroxyl ethers, e.g. N- hydrocarbyloxy substituted hindered amine compounds, by the reaction of the corresponding N-oxyl intermediate with a hydrocarbon in the presence of an organic hydroperoxide and a copper catalyst.
- nitroxyl ethers e.g. N- hydrocarbyloxy substituted hindered amine compounds
- WO 03/045919 describes a process for the preparation of nitroxyl ethers, e.g. N-hydrocarbyl- oxy substituted hindered amine compounds, by the reaction of the corresponding N-oxyl intermediate with a hydrocarbon in the presence of an organic hydroperoxide and an iodide catalyst.
- nitroxyl ethers e.g. N-hydrocarbyl- oxy substituted hindered amine compounds
- One aspect of the invention is a process for the preparation of a sterically hindered nitroxyl ether of formula (I) or (II)
- n is a number from 1 to 10 and Ri is CrC 5 alkyl; which comprises in the case of the stericallly hindered nitroxyl ether of formula (I) the steps a) reacting a compound of formula (Ia) with n-hexylaldehyde, n-pentylaldehyde, n-butyraldehyde, n-propylaldehyde or acetaldehyde and a hydroperoxide in the presence of a metal catalyst; or
- Ri in formula (I) is n-propyl and the aldehyde is butyraldehyde.
- n is a mixture of the numbers 1 , 3, 5 and 7.
- hydroperoxide is of formula (II) (
- the hydroperoxide is tert. butyl hydroperoxide, cumyl hydroperoxide or H 2 O 2 .
- the hydroperoxide and in particular H 2 O 2 is typically dissolved in water and may be used in a concentration from 1 % to 90% by weight based on the weight of the total solution. Preferably the concentration is between 20% and 70% by weight.
- the hydroperoxide and in particular H 2 O 2 can also be prepared in situ, for example by electrolysis.
- the metal catalyst can be chosen from the group of transition metal catalysts or from the group of metal catalysts with Lewis-Acid character or of the group of water soluble ionic compounds and is preferably selected from the group consisting of scandium, titanium, vanadium, chromium, manganese, iron, cobalt, nickel, copper, zinc, gallium, germanium, yttrium, zirconium, niobium, molybdenum, ruthenium, rhodium, palladium, silver, cadmium, indium, tin, antimony, lanthanum, cerium, hafnium, tantalum, tungsten, rhenium, osmium, iridium, platinum, gold, mercury, thallium, lead, bismuth, aluminum, magnesium, calcium, lithium, barium, boron, sodium, potassium, cesium, strontium or combinations thereof.
- the metal catalyst can be bound to an organic or inorganic polymer backbone, providing a homogenous or heterogen
- the metal catalyst mentioned above may contain anionic ligands commonly known in com- plex chemistry of transition metals, such as anions derived from inorganic or organic acids, examples being halides, e.g. F ⁇ , C ⁇ ⁇ , Br ⁇ or l ⁇ , fluoro complexes of the type BF 4 " , PF 6 " , SbF 6 - or AsF 6 -, anions of oxygen acids, alcoholates or anions of cyclopentadiene or oxides.
- anionic ligands commonly known in com- plex chemistry of transition metals, such as anions derived from inorganic or organic acids, examples being halides, e.g. F ⁇ , C ⁇ ⁇ , Br ⁇ or l ⁇ , fluoro complexes of the type BF 4 " , PF 6 " , SbF 6 - or AsF 6 -, anions of oxygen acids, alcoholates or anions of cyclopentadiene or
- Anionic and neutral ligands may also be present up to the preferred coordination number of the complex cation of the metal catalyst, especially four, five or six. Additional negative charges are counterbalanced by cations, especially monovalent cations such as Na + , K + , NH 4 + or (C r C 4 alkyl) 4 N + . These anionic and neutral ligands may be applied to adjust the reactivity of the corresponding transition metal, e. g. in order to diminish the catalyst activity.
- the neutral ligands are commonly known in complex chemistry of transition metals.
- Suitable inorganic ligands are selected from the group consisting of aquo (H 2 O), amino, nitrogen, carbon monoxide and nitrosyl.
- Suitable organic ligands are selected from the group consisting of phosphines, e.g.
- the metal catalyst in particular the transition metal catalyst can further contain heterocyclic e ⁇ donor ligands which are derived, for example, from unsubstituted or substituted heteroarenes from the group consisting of furan, thiophene, pyrrole, pyridine, bis-pyridine, picolylimine, phenanthroline, pyrimidine, bis-pyrimidine, pyrazine, indole, salen, coumarone, thionaphthene, carbazole, dibenzofuran, dibenzothiophene, pyrazole, imidazole, benzimidazole, oxazole, thiazole, bis-thiazole, isoxazole, isothiazole, quinoline, bis-quinoline, isoquinoline, bis-isoquinoline, acridine, chromene, phenazine, phenoxazine, phenothiazine, triazine, thianthrene,
- the metal catalyst is a salt or a complex of Ag, Mn, Fe, Cu, Zr, Na, Mg, Ca, Al, Pd, In or Ce in any oxidation state.
- the metal catalyst is a salt or a complex of Fe, Cu, Mn, Na, Mg, Pd, In, Zr or Bi in any oxidation state.
- the metal catalyst is a Fe 2+ or Fe 3+ , a Cu + or Cu 2+ , a Na + or a Ca 2+ salt.
- Typical counter ions for the above metal ions are derived from inorganic or organic acids.
- Examples for counter ions are Cl “ , NO 3 “ , SO 4 2” , CO 3 2” , PO 4 3” , CH 3 COO “ , SO 3 2” or CF 3 SO 3 " .
- the metal catalyst is typically present in an amount of 0.0005 to 10.0 molar equivalents, dependent on the metal.
- Cu + or Cu 2+ is preferably used in amounts of 0.0005 to 0.2 molar equivalents and more preferably from 0.005 to 0.05 molar equivalents, based on the molar equivalents of the sterically hindered nitroxyl radical.
- Na + is preferably used in amounts from 0.005 to 3.0 molar equivalents and more preferably from 0.01 to 2.0 molar equivalents, based on the molar equivalents of the sterically hindered nitroxyl radical.
- the process is typically carried out at normal atmospheric pressure. In the case of aldehydes with very low boiling points, it may be advantageous to apply pressure during the reaction.
- the reaction time is usually short, depending on the sterically hindered nitroxyl radical used. For example the reaction time varies from 0.5 hours to 20 hours, for instance it is from 1 hour to 7 hours.
- the reaction is typically carried out at a temperature between 0° and 100° C depending on the catalyst used.
- the reaction temperature is in particular between 10° and 60° C and preferably between 25° and 50° C. If Na + is used, the reaction temperature is preferably between 25° and 100° C, more preferably between 60° and 100° C.
- the pH value may vary from 1 to 10. Preferably it is neutral to slightly acidic, for instance pH 4 to 6.
- inorganic and organic acids may be used to keep the pH value in the preferred range, examples for inorganic and organic acids have already been mentioned above.
- Typical examples are HCI, H 2 SO 4 , H 3 PO 4 , CH 3 COOH, CH 3 SO 3 H or buffer systems based, for example, on H 3 PO 4 or CH 3 COOH.
- the reaction can be carried out with or without additional solvents.
- Two phase systems may also prevail in those cases, where the aldehyde is not completely soluble in the aqueous phase.
- the sterically hindered nitroxyl radical may be either in the aqueous phase or in the organic phase and the aldehyde in the respective other phase.
- a phase transfer catalyst typically an amphiphilic molecule, or a suitable inert cosolvent.
- phase transfer catalysts are salts containing anions, such as halides, hydroxides, hydrogensulfates, phosphates of tetraalkylammonium and alkyl arylphosphonium compounds.
- Current examples of phase transfer processes can be found, for example, in the Chemical Industry Digest (2005), 18(7), 49-62, Topics in Catalysis (2004), 29(3-4), 145-161 or in lnterfacial Catalysis (2003), 159-201.
- Typical inert solvents are for example, water, alkanes, toluene, xylene, nitrobenzene, acetic acid, esters such as ethyl acetate, alcohols such as ethanol or tert-butanol, halogenated solvents such as methylene chloride or chlorobenzene, ionic liquids, ethers such as tetrahydrofuran or tert.-butylmethylether, NMP or supercritical carbon dioxide.
- hydroperoxide-stable solvents may be used in this process.
- alcohols may be used as co-solvents in the present process, in particular those which form the employed aldehyde upon oxidation.
- ethanol can be used in such processes, where the radical-forming species is acetaldehyde.
- the aldehyde and the hydroperoxide can be used in a wide concentration range. They are typically used in an excess amount, compared to the sterically hindered nitroxyl radical. Typically for the aldehyde is an excess of 1.05 to 20 mol equivalents, for example 1.25 to 5 mol equivalents, based on the molar amount of the sterically hindered nitroxyl radical.
- the hydroperoxide is typically used in an excess of 1 to 10 mol equivalents, for example 1.5 to 3 mol equivalents, based on the molar amount of the sterically hindered nitroxyl radical.
- the reaction can be carried out in several ways. For instance the sterically hindered nitroxyl radical is dissolved in the aldehyde. If necessary an inert cosolvent is added. To this solution an aqueous solution of the hydroperoxide is added and after a short time of stirring the metal catalyst is added either dissolved in water or in an appropriate solvent or directly, for example, in the form of a powder. The mixture is stirred and reacted for an appropriate time. In another embodiment of the process it is possible to dissolve the aldehyde in an appropriate solvent and to add the hydroperoxide subsequently. After a certain time the hindered nitroxide radical is added, either dissolved in an appropriate solvent or neat, followed by the catalyst.
- the hindered nitroxyl radical in an appropriate solvent, adding the catalyst and then adding the aldehyde and the hydroperoxide over the course of time - either simultaneously or one after another.
- the oxidant is added over the course of time to a solution of the hindered nitroxyl radical and the aldehyde and the metal catalyst in an appropriate solvent or the oxidant and the aldehyde are added over the course of time to a solution of the hindered nitroxyl radical and the metal catalyst.
- a specific embodiment of the invention is the process for the preparation of a sterically hindered nitroxyl ether of formula (I) or (II)
- n is a number from 1 to 10 and Ri is propyl;
- R 1 in formula (I) is propyl
- the resulting compound of formula (I) is Tinuvin NOR 371 (RTM) a light stabilizer of Ciba Specialty Chemicals.
- the compound of formula (M) is Flamestab 1 16 (RTM) a flame retardant of Ciba Specialty Chemicals.
- the sterically hindered nitroxyl radical starting materials are known in the art; they may be prepared by oxidation of the corresponding N-H sterically hindered amine with a suitable oxygen donor, e.g. by the reaction of the corresponding N-H sterically hindered amine with hydrogen peroxide and sodium tungstate as described by E. G. Rozantsev et al., in Synthesis, 1971 , 192; or with tert-butyl hydroperoxide and molybdenum (Vl) as taught in United States Patent No. 4,691 ,015, or obtained in analogous manner.
- sterically hindered NH compounds sterically hindered NH compounds
- the oxidation may be carried out in analogy to the oxidation of 4-hydroxy-2, 2,6,6- tetramethylpiperidine described in US 5,654,434 with hydrogen peroxide.
- Another also suitable oxidation process is described in WO 00/40550 using peracetic acid.
- An exhaustive description of the nitroxide (nitroxyl radical) chemistry can be found, for example, in L. B. Volodarsky, V.A. Reznikov, V.I. Ovcharenko.: "Synthetic Chemistry of Stable Nitroxides", CRC Press, 1994.
- the compound of formula (I) is prepared according to the following reaction scheme starting from 1-oxyl 2,2,6, 6-tetramethylpiperidine-4-oxo
- Chimassorb 2020 which is the oxidation product of Chimassorb 2020 (RTM).
- RTM Chimassorb 2020
- n is a mixture of numbers between 1 and 10
- M n by GPC
- M w /M n is typically 1.2.
- Hydrogen peroxide (12Og) is dosed in while maintaining the reaction temperature at 35 0 C.
- the batch is on hold at 35 0 C until the reaction is complete.
- a combination of sodium sulfite and sodium hydroxide solution is added.
- t-Butanol / water is stripped off under partial vacuum (15 - 20 mm Hg.) and the t-butanol is replaced by hexane.
- the batch pH is adjusted to 7 with a small quantity of acid.
- An EDTA wash is performed and the product is isolated with hot water stripping and dried in an oven at 8O 0 C to constant weight. Yield: 1 17g; yellow powder.
- aqueous phase is separated and discarded.
- the organic phase is extracted with water (50 ml), then added dropwise to methanol (300 ml).
- Water (50 ml) is added with stirring, and the pH-value is adjusted to 8 - 9 by adding aqueous sodium carbonate solution.
- 1-propoxy-2,2,6,6-tetramethyl-piperidin-4-yl-amine, compound Q can be prepared using a 7M solution of ammonia in methanol, followed by hydrogenation
- This compound can be transformed into butyl-(1-propoxy-2,2,6,6-tetramethyl-piperidin-4-yl)- amine, compound S, or N,N'-Bis-(2,2,6,6-tetramethyl-1-propoxy-piperidin-4-yl)-hexane-1 ,6- diamine, compound P, by known methods (e.g. reductive amination or alkylation employing butyl bromide/chloride).
- aqueous phase is split off and the organic phase heated to 70°C followed by the slow addition of 33.2g (0.065mol) compound P and 33g water. After addition of 2Og (0.15mol) 30% aqueous sodium hydroxide solution, the mixture is stirred at 80°C for 2h. The structure is confirmed by NMR.
- the hot aqueous phase is split off.
- the organic phase is cooled down to 25°C and transferred into an autoclave. After addition of 66.4g (0.13mol) compound P and 28.6g (0.143mol) NaOH (aqueous 20%) the autoclave is sealed and heated to 175°C where it is left for 4 hours.
- butyl-(1-cyclohexyloxy-2,2,6,6-tetramethyl-piperidin-4-ylidene)-amine compound L, can be prepared starting from compound B.
- Butyl-(1 -cvclohexyloxy-2,2,6,6-tetramethyl-piperidin-4-yl)-amine, compound D In a 400 ml stainless steel autoclave 2.0 g 10% palladium on charcoal are added to a solution of 30 g (98 mmol) compound M in 200 ml methanol. The autoclav is pressurized with 5 bar of hydrogen and stirred at 60 °C for 2.5h. The reaction mixture is filtered over celite and the methanol removed in vacuo. The obtained oily material is subjected to column chromatography (hexane/acetone 4:1 ; 0.5% triethylamine) to give 28.1 g (94%) pure product; white solid.
- 2,4-bis-[(1 -cyclohex-S-enyloxy ⁇ . ⁇ . ⁇ -tetramethyl-piperidin ⁇ -ylJbutylaminoJ- ⁇ - chloro-s-triazine, compound G can be prepared using 1 ,2,3,6-tetrahydrobenzaldehyde.
- 1-Cyclohex-3-enyloxy-2,2,6,6-tetramethyl-piperidin-4-ol, compound H can be prepared using 1 ,2,3,6-tetrahydrobenzaldehyde.
- i-cyclohex-S-enyloxy ⁇ . ⁇ . ⁇ -tetramethyl-piperidin ⁇ -yl-toluene ⁇ -sulfonic acid ester compound J
- i-cyclohex-S-enyloxy ⁇ . ⁇ . ⁇ -tetramethyl-piperidin-4-ol Yield: 63%; white solid.
- butyl-(1-cyclohex-3-enyloxy-2,2,6,6-tetramethyl-piperidin-4-yl)-amine compound N, can be prepared starting from i-cyclohex-S-enyloxy ⁇ . ⁇ . ⁇ -tetramethyl-piperidin ⁇ -yl- toluene-4-sulfonic acid. Yield: 9%; white solid.
- a mixture of 6g (8.2mmol) of compound F, 0.47g (2.7mmol) N,N'-bis(3- aminopropyl)ethylenediamine and 1.7g (8.5mmol) aqueous 20% NaOH solution is heated in an autoclave at 125°C for 18h.
- the mixture is cooled down to 25°C, diluted with hexane and the aqueous phase split off.
- the organic phase is washed with water and sat. NaCI sol., dryed over sodium sulfate, filtered and concentrated on a rotary evaporator.
- the crude oil is slowly added to boiling methanol, yielding a white precipitate.
- the suspension is treated with ultrasound, filtered, and the filtercake is dried to afford the product as a white powder.
- the product exhibits higher quality compared to state-of-the-art material in terms of transmission and residual copper content:
- the amount of residual copper is below 0.1 ppm as measured by atomic absorption spectroscopy.
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Description
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Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT07786825T ATE449072T1 (en) | 2006-07-05 | 2007-06-25 | METHOD FOR PRODUCING STERICALLY HINDERED NITROXYL ETHER |
EP07786825A EP2035382B1 (en) | 2006-07-05 | 2007-06-25 | Process for the preparation of sterically hindered nitroxyl ethers |
CA2654837A CA2654837C (en) | 2006-07-05 | 2007-06-25 | Process for the preparation of sterically hindered nitroxyl ethers |
KR1020087031543A KR101454702B1 (en) | 2006-07-05 | 2007-06-25 | Process for the preparation of sterically hindered nitroxyl ethers |
DE602007003357T DE602007003357D1 (en) | 2006-07-05 | 2007-06-25 | METHOD FOR THE PRODUCTION OF STERRICALLY PREVENTED NITROXYL ETHER |
US12/308,595 US8481726B2 (en) | 2006-07-05 | 2007-06-25 | Process for the preparation of sterically hindered nitroxyl ethers |
JP2009517150A JP2009541429A (en) | 2006-07-05 | 2007-06-25 | Method for producing sterically hindered nitroxyl ether |
MX2009000047A MX2009000047A (en) | 2006-07-05 | 2007-06-25 | Process for the preparation of sterically hindered nitroxyl ethers. |
CN2007800253747A CN101484423B (en) | 2006-07-05 | 2007-06-25 | Process for the preparation of sterically hindered nitroxyl ethers |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06116619 | 2006-07-05 | ||
EP06116619.5 | 2006-07-05 | ||
EP07106899.3 | 2007-04-25 | ||
EP07106899 | 2007-04-25 |
Publications (1)
Publication Number | Publication Date |
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WO2008003605A1 true WO2008003605A1 (en) | 2008-01-10 |
Family
ID=38894217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2007/056301 WO2008003605A1 (en) | 2006-07-05 | 2007-06-25 | Process for the preparation of sterically hindered nitroxyl ethers |
Country Status (11)
Country | Link |
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US (1) | US8481726B2 (en) |
EP (1) | EP2035382B1 (en) |
JP (1) | JP2009541429A (en) |
KR (1) | KR101454702B1 (en) |
AT (1) | ATE449072T1 (en) |
CA (1) | CA2654837C (en) |
DE (1) | DE602007003357D1 (en) |
ES (1) | ES2335320T3 (en) |
MX (1) | MX2009000047A (en) |
TW (1) | TWI389887B (en) |
WO (1) | WO2008003605A1 (en) |
Cited By (11)
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WO2011029744A1 (en) | 2009-09-10 | 2011-03-17 | Basf Se | Sterically hindered amine stabilizer |
WO2011107513A1 (en) | 2010-03-05 | 2011-09-09 | Basf Se | Sterically hindered amines |
WO2011107515A2 (en) | 2010-03-05 | 2011-09-09 | Basf Se | Sterically hindered amines |
WO2012052377A1 (en) | 2010-10-20 | 2012-04-26 | Basf Se | Sterically hindered amine light stabilizers with mixed functionalization |
WO2012052376A1 (en) | 2010-10-20 | 2012-04-26 | Basf Se | Oligomeric light stabilizers with a specific functionalization |
WO2015130391A1 (en) | 2014-02-28 | 2015-09-03 | Exxonmobil Chemical Patents Inc. | Mooney viscosity stable brominated elastomers |
WO2016175938A1 (en) | 2015-04-30 | 2016-11-03 | Exxonmobil Chemical Patents Inc. | System and process for halogenating olefinic-derived elastomers in the bulk phase |
WO2017131869A1 (en) | 2016-01-29 | 2017-08-03 | Exxonmobil Chemical Patents Inc. | System and process for the production of functionalized olefinic-based polymer |
WO2021005011A1 (en) | 2019-07-09 | 2021-01-14 | Basf Se | Tableting of specific polymer stabilizers |
DE112021001158T5 (en) | 2020-02-21 | 2022-12-22 | Ps Japan Corporation | Styrene-based resin composition, styrene-based flame retardant resin composition, molded article and patch antenna |
WO2023194065A1 (en) | 2022-04-04 | 2023-10-12 | Zedda Innovation Consulting | Process for the preparation of sterically hindered nitroxyl ethers |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112126060B (en) | 2019-06-25 | 2022-05-31 | 北京天罡助剂有限责任公司 | Polymeric high-molecular steric hindrance amine and preparation method thereof |
CN112250668A (en) * | 2020-10-10 | 2021-01-22 | 利安隆凯亚(河北)新材料有限公司 | Preparation method of N-alkoxy hindered amine light stabilizer and intermediate thereof |
CN113354813B (en) * | 2021-06-02 | 2023-07-04 | 宿迁联盛科技股份有限公司 | Preparation method of low-alkalinity hindered amine light stabilizer NOR371 |
Citations (6)
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US4921962A (en) * | 1988-10-19 | 1990-05-01 | Ciba-Geigy Corporation | Process for preparing N-hydrocarbyloxy derivatives of sterically hindered amines |
EP0569334A1 (en) * | 1992-05-07 | 1993-11-10 | Ciba-Geigy Ag | Process for preparing N-methoxy derivatives of 4-hydroxy-2,2,6,6-tetramethylpiperidine and 2,2,6,6-tetramethyl-4-piperidone |
DE10008367A1 (en) * | 1999-02-25 | 2000-08-31 | Ciba Sc Holding Ag | New 1-alkoxy-substituted hindered 2,2,6,6-tetramethylpiperidine group-containing amines useful as stabilizers for (thermoplastic) polymers, coatings, color photographic materials and printing inks |
WO2001092228A2 (en) * | 2000-05-26 | 2001-12-06 | Ciba Specialty Chemicals Holding Inc. | Process for the synthesis of amine ethers from secondary amino oxides |
WO2005005388A1 (en) * | 2003-07-14 | 2005-01-20 | Ciba Specialty Chemicals Holding Inc. | Hydrogen peroxide catalyzed process for the preparation of sterically hindered n-hydrocarbyloxyamines |
WO2005090307A1 (en) * | 2004-03-15 | 2005-09-29 | Ciba Specialty Chemicals Holding Inc. | A process for the synthesis of amine ethers |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200407307A (en) * | 2001-11-26 | 2004-05-16 | Ciba Sc Holding Ag | Process for the synthesis of amine ethers from secondary amino oxides |
WO2008003602A1 (en) * | 2006-07-05 | 2008-01-10 | Ciba Holding Inc. | Process for the preparation of sterically hindered nitroxyl ethers |
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2007
- 2007-06-25 ES ES07786825T patent/ES2335320T3/en active Active
- 2007-06-25 CA CA2654837A patent/CA2654837C/en not_active Expired - Fee Related
- 2007-06-25 MX MX2009000047A patent/MX2009000047A/en active IP Right Grant
- 2007-06-25 AT AT07786825T patent/ATE449072T1/en not_active IP Right Cessation
- 2007-06-25 JP JP2009517150A patent/JP2009541429A/en not_active Withdrawn
- 2007-06-25 US US12/308,595 patent/US8481726B2/en active Active
- 2007-06-25 KR KR1020087031543A patent/KR101454702B1/en not_active IP Right Cessation
- 2007-06-25 EP EP07786825A patent/EP2035382B1/en active Active
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Also Published As
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EP2035382A1 (en) | 2009-03-18 |
US8481726B2 (en) | 2013-07-09 |
MX2009000047A (en) | 2009-01-23 |
DE602007003357D1 (en) | 2009-12-31 |
TW200811106A (en) | 2008-03-01 |
ES2335320T3 (en) | 2010-03-24 |
TWI389887B (en) | 2013-03-21 |
JP2009541429A (en) | 2009-11-26 |
US20110160453A1 (en) | 2011-06-30 |
KR20090031523A (en) | 2009-03-26 |
CA2654837C (en) | 2015-11-24 |
KR101454702B1 (en) | 2014-10-27 |
EP2035382B1 (en) | 2009-11-18 |
CA2654837A1 (en) | 2008-01-10 |
ATE449072T1 (en) | 2009-12-15 |
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