WO2007103563A3 - Pharmaceutical formulations containing metformin - Google Patents

Pharmaceutical formulations containing metformin Download PDF

Info

Publication number
WO2007103563A3
WO2007103563A3 PCT/US2007/006055 US2007006055W WO2007103563A3 WO 2007103563 A3 WO2007103563 A3 WO 2007103563A3 US 2007006055 W US2007006055 W US 2007006055W WO 2007103563 A3 WO2007103563 A3 WO 2007103563A3
Authority
WO
WIPO (PCT)
Prior art keywords
metformin
glimepiride
pharmaceutical formulations
formulations containing
containing metformin
Prior art date
Application number
PCT/US2007/006055
Other languages
French (fr)
Other versions
WO2007103563A2 (en
Inventor
Krishna Vishnupad
Original Assignee
Neurosci Inc
Krishna Vishnupad
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosci Inc, Krishna Vishnupad filed Critical Neurosci Inc
Priority to EP07752735A priority Critical patent/EP2001302A2/en
Priority to CA002645318A priority patent/CA2645318A1/en
Publication of WO2007103563A2 publication Critical patent/WO2007103563A2/en
Publication of WO2007103563A3 publication Critical patent/WO2007103563A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Controlled delivery and instant release combination compositions of metformin or salts thereof and glimepiride and the process of making the same are disclosed. Metformin and glimepiride are granulated with a binder and further dispersed in a rate-controlling matrix that results in a controlled release formulation that increases patient compliance. In a further illustrative embodiment metformin and glimepiride are formulated in an instant release presentation using pharmaceutical excipients known in the art.
PCT/US2007/006055 2006-03-09 2007-03-09 Pharmaceutical formulations containing metformin WO2007103563A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07752735A EP2001302A2 (en) 2006-03-09 2007-03-09 Pharmaceutical formulations containing metformin
CA002645318A CA2645318A1 (en) 2006-03-09 2007-03-09 Pharmaceutical formulations containing metformin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78094406P 2006-03-09 2006-03-09
US60/780,944 2006-03-09

Publications (2)

Publication Number Publication Date
WO2007103563A2 WO2007103563A2 (en) 2007-09-13
WO2007103563A3 true WO2007103563A3 (en) 2008-01-03

Family

ID=38475600

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/006055 WO2007103563A2 (en) 2006-03-09 2007-03-09 Pharmaceutical formulations containing metformin

Country Status (3)

Country Link
EP (1) EP2001302A2 (en)
CA (1) CA2645318A1 (en)
WO (1) WO2007103563A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110801443A (en) * 2019-12-03 2020-02-18 仁和堂药业有限公司 Metformin hydrochloride sustained-release preparation and quality detection method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060002998A1 (en) * 2002-11-15 2006-01-05 Anupam Trehan Pharmaceutical dosage forms of biguanide-sulfonylurea combinations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060002998A1 (en) * 2002-11-15 2006-01-05 Anupam Trehan Pharmaceutical dosage forms of biguanide-sulfonylurea combinations

Also Published As

Publication number Publication date
CA2645318A1 (en) 2007-09-13
WO2007103563A2 (en) 2007-09-13
EP2001302A2 (en) 2008-12-17

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