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Light-curable bone growth material for treating dental bone defects

Info

Publication number
WO2007079053A3
WO2007079053A3 PCT/US2006/049198 US2006049198W WO2007079053A3 WO 2007079053 A3 WO2007079053 A3 WO 2007079053A3 US 2006049198 W US2006049198 W US 2006049198W WO 2007079053 A3 WO2007079053 A3 WO 2007079053A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
bone
material
carrier
particulate
growth
Prior art date
Application number
PCT/US2006/049198
Other languages
French (fr)
Other versions
WO2007079053A2 (en )
Inventor
Brent Lee Atkinson
Katherine Suzanne Walline
Original Assignee
Brent Lee Atkinson
Dentsply Int Inc
Katherine Suzanne Walline
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/02Use of preparations for artificial teeth, for filling or for capping teeth
    • A61K6/08Use of natural or synthetic resins
    • A61K6/087Compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/0047Preparations for dentistry characterised by the presence of organic or organo-metallic additives
    • A61K6/0052Photochemical radical initiators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/02Use of preparations for artificial teeth, for filling or for capping teeth
    • A61K6/08Use of natural or synthetic resins
    • A61K6/097Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • A61L27/365Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Abstract

Improved compositions comprising a mixture of particulate bone growth material and polymeric carrier are provided. The particulate is preferably porous, resorbable, anorganic bone material. The polymeric carrier can be light-cured to form a cross-linked, biodegradable hydrogel. In one version, the bone growth material is a synthetic peptide bound to anorganic bone matrix particles and the carrier is methacrylated sodium hyaluronate (MHy) or methacrylated hydroxyethylcellulose (MHEC). The composition is particularly suitable for repairing defective dental and orthopedic bone tissue. The particulate and hydrogel carrier are biodegradable so the composition can be replaced by new bone formation over time.
PCT/US2006/049198 2005-12-28 2006-12-22 Light-curable bone growth material for treating dental bone defects WO2007079053A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US75445305 true 2005-12-28 2005-12-28
US60/754,453 2005-12-28

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2008548665A JP2009522001A (en) 2005-12-28 2006-12-22 Photocurable bone growth material for treating bone defects in teeth
CA 2634245 CA2634245C (en) 2005-12-28 2006-12-22 Light-curable bone growth material for treating dental bone defects
EP20060848115 EP1973513B1 (en) 2005-12-28 2006-12-22 Light-curable bone growth material for treating dental bone defects
DE200660018196 DE602006018196D1 (en) 2005-12-28 2006-12-22 Light-curable bone growth material for treatment of dental bone defects

Publications (2)

Publication Number Publication Date
WO2007079053A2 true WO2007079053A2 (en) 2007-07-12
WO2007079053A3 true true WO2007079053A3 (en) 2008-07-31

Family

ID=38228802

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/049198 WO2007079053A3 (en) 2005-12-28 2006-12-22 Light-curable bone growth material for treating dental bone defects

Country Status (6)

Country Link
US (4) US20070269518A1 (en)
JP (1) JP2009522001A (en)
CA (1) CA2634245C (en)
DE (1) DE602006018196D1 (en)
EP (1) EP1973513B1 (en)
WO (1) WO2007079053A3 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2908775B1 (en) * 2006-11-17 2012-08-31 Biomatlante Hydrogel and biomedical applications
EP2234559A1 (en) * 2008-01-09 2010-10-06 Innovative Health Technologies, Llc Implant pellets and methods for performing bone augmentation and preservation
WO2009145813A1 (en) * 2008-03-04 2009-12-03 Qd Vision, Inc. Particles including nanoparticles, uses thereof, and methods
US20090259263A1 (en) * 2008-04-11 2009-10-15 Biomet Microfixation, Inc. Apparatus and methods of fixating bone
WO2009155583A1 (en) * 2008-06-19 2009-12-23 The Trustees Of The University Of Pennsylvania Biomaterials for tissue replacement
GB0813659D0 (en) 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
WO2010056899A1 (en) * 2008-11-12 2010-05-20 The Trustees Of The University Of Pennsylvania Biomaterials for tissue replacement
WO2011031871A1 (en) 2009-09-09 2011-03-17 Qd Vision, Inc. Particles including nanoparticles, uses thereof, and methods
WO2011031876A1 (en) 2009-09-09 2011-03-17 Qd Vision, Inc. Formulations including nanoparticles
JP2013525299A (en) 2010-04-16 2013-06-20 アパテック リミテッド Biological material
CN104394888A (en) * 2012-05-30 2015-03-04 克洛克斯科技公司 Compositions and methods for biophotonic bone reconstruction
CA2987619A1 (en) * 2015-05-29 2016-12-08 George W. Kay Compositions and methods for adhesion to surfaces

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837752A (en) * 1997-07-17 1998-11-17 Massachusetts Institute Of Technology Semi-interpenetrating polymer networks
WO2004011053A1 (en) * 2002-07-31 2004-02-05 Dentsply International Inc. Bone repair putty comprising porous particulate and carrier gel
WO2004075862A2 (en) * 2003-02-27 2004-09-10 Arthur Ashman Crosslinkable polymeric materials and their applications

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354736A (en) * 1989-08-14 1994-10-11 Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
US5635482A (en) * 1989-08-14 1997-06-03 The Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
US5626863A (en) * 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
JP2855307B2 (en) * 1992-02-05 1999-02-10 生化学工業株式会社 Photoreactive glycosaminoglycans, crosslinked glycosaminoglycan and a process for their preparation
US5902599A (en) * 1996-02-20 1999-05-11 Massachusetts Institute Of Technology Biodegradable polymer networks for use in orthopedic and dental applications
US6007833A (en) * 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
JP4172176B2 (en) * 2000-12-19 2008-10-29 生化学工業株式会社 Photoreactive hyaluronic acid and its manufacturing method, and photocured crosslinked-hyaluronic acid and medical materials
JP2006500978A (en) * 2002-08-20 2006-01-12 イグザクテック・インコーポレイテッド Transport and compositions for delivering a bone growth inducing substance, and production and application of the composition
US20050069572A1 (en) * 2002-10-09 2005-03-31 Jennifer Elisseeff Multi-layered polymerizing hydrogels for tissue regeneration
KR20050055760A (en) * 2002-10-11 2005-06-13 노보셀, 인크 Implantation of encapsulated biological materials for treating diseases
KR20050092795A (en) * 2003-01-31 2005-09-22 짐머 오르쏘바이올로직스 인코포레이티드 Hydrogel compositions comprisign nucleus pulposus tissue

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837752A (en) * 1997-07-17 1998-11-17 Massachusetts Institute Of Technology Semi-interpenetrating polymer networks
WO2004011053A1 (en) * 2002-07-31 2004-02-05 Dentsply International Inc. Bone repair putty comprising porous particulate and carrier gel
WO2004075862A2 (en) * 2003-02-27 2004-09-10 Arthur Ashman Crosslinkable polymeric materials and their applications

Also Published As

Publication number Publication date Type
CA2634245C (en) 2013-12-10 grant
US20110045084A1 (en) 2011-02-24 application
EP1973513B1 (en) 2010-11-10 grant
WO2007079053A2 (en) 2007-07-12 application
CA2634245A1 (en) 2007-07-12 application
EP1973513A2 (en) 2008-10-01 application
DE602006018196D1 (en) 2010-12-23 grant
JP2009522001A (en) 2009-06-11 application
US20070269518A1 (en) 2007-11-22 application
US20100034883A1 (en) 2010-02-11 application
US20120129134A1 (en) 2012-05-24 application

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