WO2007072290A3 - Method of performing a microarray assay - Google Patents

Method of performing a microarray assay Download PDF

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Publication number
WO2007072290A3
WO2007072290A3 PCT/IB2006/054737 IB2006054737W WO2007072290A3 WO 2007072290 A3 WO2007072290 A3 WO 2007072290A3 IB 2006054737 W IB2006054737 W IB 2006054737W WO 2007072290 A3 WO2007072290 A3 WO 2007072290A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological compounds
substrate
labels
target biological
different
Prior art date
Application number
PCT/IB2006/054737
Other languages
French (fr)
Other versions
WO2007072290A2 (en
Inventor
Johannes Bacher
Andreas Boos
Gerd Luedke
Original Assignee
Koninkl Philips Electronics Nv
Philips Intellectual Property
Johannes Bacher
Andreas Boos
Gerd Luedke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv, Philips Intellectual Property, Johannes Bacher, Andreas Boos, Gerd Luedke filed Critical Koninkl Philips Electronics Nv
Priority to EP06832196A priority Critical patent/EP1966391A2/en
Priority to JP2008546715A priority patent/JP2009520977A/en
Priority to US12/158,074 priority patent/US20080269069A1/en
Publication of WO2007072290A2 publication Critical patent/WO2007072290A2/en
Publication of WO2007072290A3 publication Critical patent/WO2007072290A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Disclosed is a method for performing a microarray assay on one or more sample fluid(s), sais fluids comprising target biological compounds. The method comprises the step of tagging said target biological compounds with labels. The following step comprises contacting said sample fluid(s) with a substrate and detecting the presence of said labels at the surface of said substrate. The method is suitable for the simultaneous analysis, in one microarray, of one or more types of target biological compounds, in one or more sample fluid(s). To this end each of said types of biological compounds is tagged with a different label so that target biological compounds belonging to different sample fluids have different labels. Said different labels are discriminable upon detection at the surface of said substrate. Also disclosed is the use of a polymer substrate in a method for performing a microarray assay.
PCT/IB2006/054737 2005-12-21 2006-12-11 Method of performing a microarray assay WO2007072290A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06832196A EP1966391A2 (en) 2005-12-21 2006-12-11 Method of performing a microarray assay
JP2008546715A JP2009520977A (en) 2005-12-21 2006-12-11 How to perform a microarray assay
US12/158,074 US20080269069A1 (en) 2005-12-21 2006-12-11 Method of Performing a Microarray Assay

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05112548 2005-12-21
EP05112548.2 2005-12-21

Publications (2)

Publication Number Publication Date
WO2007072290A2 WO2007072290A2 (en) 2007-06-28
WO2007072290A3 true WO2007072290A3 (en) 2007-10-11

Family

ID=37905868

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/054737 WO2007072290A2 (en) 2005-12-21 2006-12-11 Method of performing a microarray assay

Country Status (5)

Country Link
US (1) US20080269069A1 (en)
EP (1) EP1966391A2 (en)
JP (1) JP2009520977A (en)
CN (1) CN101341261A (en)
WO (1) WO2007072290A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8492098B2 (en) 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
US11237171B2 (en) 2006-02-21 2022-02-01 Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US20110195852A1 (en) 2007-08-30 2011-08-11 Trustees Of Tufts College Methods for determining the concentration of an analyte in solution
US8236574B2 (en) 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
US9678068B2 (en) 2010-03-01 2017-06-13 Quanterix Corporation Ultra-sensitive detection of molecules using dual detection methods
US8415171B2 (en) 2010-03-01 2013-04-09 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
JP5363663B2 (en) 2010-03-01 2013-12-11 クワンテリクス コーポレーション Method or system for extending the dynamic range in an assay to detect molecules or particles
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
US20140302532A1 (en) 2011-04-12 2014-10-09 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury
WO2014113502A1 (en) 2013-01-15 2014-07-24 Quanterix Corporation Detection of dna or rna using single molecule arrays and other techniques
FR3023003B1 (en) * 2014-06-27 2016-07-15 Bio-Rad Innovations SYNERGISTIC COMBINATION OF BIOMARKERS FOR THE DETECTION AND EVALUATION OF A HEPATIC FIBROSIS
JP7273022B2 (en) 2017-07-19 2023-05-12 バイオ―ラッド ヨーロッパ ゲーエムベーハー Combination of biomarkers to simultaneously assess non-alcoholic steatohepatitis and liver fibrosis status

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0219695A1 (en) * 1985-09-30 1987-04-29 Miles Inc. Immobilization of nucleic acids in solvolyzed nylon supports
EP1158058A1 (en) * 2000-05-19 2001-11-28 Centre National De La Recherche Scientifique Compositions and methods suitable for nucleic acid analyses
US20020192690A1 (en) * 2001-04-17 2002-12-19 Xenoport Epitope-captured antibody display
WO2003004162A1 (en) * 2001-07-02 2003-01-16 Gene Logic, Inc. Flow-thru chip cartridge, chip holder, system & method thereof
US20040086939A1 (en) * 2002-10-31 2004-05-06 Hancock Robert R. Supports treated with triamine for immobilizing biomolecules

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843789A (en) * 1995-05-16 1998-12-01 Neomecs Incorporated Method of analysis of genomic biopolymer and porous materials for genomic analyses

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0219695A1 (en) * 1985-09-30 1987-04-29 Miles Inc. Immobilization of nucleic acids in solvolyzed nylon supports
EP1158058A1 (en) * 2000-05-19 2001-11-28 Centre National De La Recherche Scientifique Compositions and methods suitable for nucleic acid analyses
US20020192690A1 (en) * 2001-04-17 2002-12-19 Xenoport Epitope-captured antibody display
WO2003004162A1 (en) * 2001-07-02 2003-01-16 Gene Logic, Inc. Flow-thru chip cartridge, chip holder, system & method thereof
US20040086939A1 (en) * 2002-10-31 2004-05-06 Hancock Robert R. Supports treated with triamine for immobilizing biomolecules

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JEREMY BUHLER: "Anatomy of a comparative gene expression study", 2002, pages 1 - 7, XP002429480, Retrieved from the Internet <URL:http://www.cs.wustl.edu/~jbuhler/research/array/> [retrieved on 20070413] *
WU YING ET AL: "Quantitative assessment of a novel flow-through porous microarray for the rapid analysis of gene expression profiles.", NUCLEIC ACIDS RESEARCH 2004, vol. 32, no. 15, 2004, pages e123, XP002429481, ISSN: 1362-4962 *

Also Published As

Publication number Publication date
CN101341261A (en) 2009-01-07
JP2009520977A (en) 2009-05-28
EP1966391A2 (en) 2008-09-10
WO2007072290A2 (en) 2007-06-28
US20080269069A1 (en) 2008-10-30

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