WO2007072038A3 - Mass spectrometer - Google Patents

Mass spectrometer Download PDF

Info

Publication number
WO2007072038A3
WO2007072038A3 PCT/GB2006/004892 GB2006004892W WO2007072038A3 WO 2007072038 A3 WO2007072038 A3 WO 2007072038A3 GB 2006004892 W GB2006004892 W GB 2006004892W WO 2007072038 A3 WO2007072038 A3 WO 2007072038A3
Authority
WO
WIPO (PCT)
Prior art keywords
ion trap
ions
electric
potential
mass analyser
Prior art date
Application number
PCT/GB2006/004892
Other languages
French (fr)
Other versions
WO2007072038A2 (en
Inventor
Martin Green
Original Assignee
Micromass Ltd
Martin Green
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB0526043A priority Critical patent/GB0526043D0/en
Priority to GB0526043.5 priority
Priority to US75811706P priority
Priority to US60/758,117 priority
Application filed by Micromass Ltd, Martin Green filed Critical Micromass Ltd
Publication of WO2007072038A2 publication Critical patent/WO2007072038A2/en
Publication of WO2007072038A3 publication Critical patent/WO2007072038A3/en

Links

Classifications

    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/422Two-dimensional RF ion traps
    • H01J49/4235Stacked rings or stacked plates
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426Methods for controlling ions
    • H01J49/427Ejection and selection methods

Abstract

An ion trap mass analyser (1) is disclosed comprising a segmented rod set. Ions are trapped radially within the mass analyser by a radial pseudo-potential well. The ions are also confined axially within the ion trap by an axial electric field. The axial electric field is substantially linear across the central section of the iøn trap, but the electric field is distorted across both ends of the ion trap. A supplemental AC voltage or potential is applied to the electrodes comprising the ion trap mass analyser (1) in order to excite resonantly ions within the ion trap (1). The distortions in the electric field at the ends of the ion trap cause the resonant frequency of ions within the ion trap to shift to either a higher or lower frequency. If the frequency of the supplemental AC voltage or potential is scanned appropriately then ions are ejected from the ion trap in a shorter period of time leading to an improvement in mass resolution.
PCT/GB2006/004892 2005-12-22 2006-12-21 Mass spectrometer WO2007072038A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB0526043A GB0526043D0 (en) 2005-12-22 2005-12-22 Mass spectrometer
GB0526043.5 2005-12-22
US75811706P true 2006-01-11 2006-01-11
US60/758,117 2006-01-11

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06820639A EP1964155B1 (en) 2005-12-22 2006-12-21 Mass spectrometer
US12/158,603 US8022358B2 (en) 2005-12-22 2006-12-21 Mass spectrometer

Publications (2)

Publication Number Publication Date
WO2007072038A2 WO2007072038A2 (en) 2007-06-28
WO2007072038A3 true WO2007072038A3 (en) 2008-03-27

Family

ID=35840903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/004892 WO2007072038A2 (en) 2005-12-22 2006-12-21 Mass spectrometer

Country Status (4)

Country Link
US (1) US8022358B2 (en)
EP (2) EP2506288B1 (en)
GB (2) GB0526043D0 (en)
WO (1) WO2007072038A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0608470D0 (en) * 2006-04-28 2006-06-07 Micromass Ltd Mass spectrometer
TWI484529B (en) * 2006-11-13 2015-05-11 Mks Instr Inc Ion trap mass spectrometer, method of obtaining mass spectrum using the same, ion trap, method of and apparatus for trapping ions in ion trap
US7842918B2 (en) * 2007-03-07 2010-11-30 Varian, Inc Chemical structure-insensitive method and apparatus for dissociating ions
WO2008129850A1 (en) * 2007-04-12 2008-10-30 Shimadzu Corporation Ion trap mass spectrograph
US7928371B2 (en) * 2007-05-03 2011-04-19 Vladimir Ryjkov Methods for penning trap mass spectroscopy
US7888635B2 (en) * 2008-05-30 2011-02-15 Battelle Memorial Institute Ion funnel ion trap and process
US8822916B2 (en) 2008-06-09 2014-09-02 Dh Technologies Development Pte. Ltd. Method of operating tandem ion traps
US8008618B2 (en) 2008-06-09 2011-08-30 Frank Londry Multipole ion guide for providing an axial electric field whose strength increases with radial position, and a method of operating a multipole ion guide having such an axial electric field
CA2720248C (en) 2008-06-09 2016-10-04 Dh Technologies Development Pte. Ltd. Method of operating tandem ion traps
US7947948B2 (en) * 2008-09-05 2011-05-24 Thermo Funnigan LLC Two-dimensional radial-ejection ion trap operable as a quadrupole mass filter
DE102008064610B4 (en) * 2008-12-30 2019-01-24 Bruker Daltonik Gmbh Excitation of ions in ICR mass spectrometers
KR101724389B1 (en) 2009-05-06 2017-04-07 엠케이에스 인스트루먼츠, 인코포레이티드 Electrostatic ion trap
US8227748B2 (en) * 2010-05-20 2012-07-24 Bruker Daltonik Gmbh Confining positive and negative ions in a linear RF ion trap
US8735807B2 (en) * 2010-06-29 2014-05-27 Thermo Finnigan Llc Forward and reverse scanning for a beam instrument
WO2012016330A1 (en) * 2010-08-04 2012-02-09 Dh Technologies Development Pte. Ltd. A linear ion trap for radial amplitude assisted transfer
DE102010034078B4 (en) * 2010-08-12 2012-06-06 Bruker Daltonik Gmbh Kingdon mass spectrometer with cylindrical electrodes
US8927940B2 (en) * 2011-06-03 2015-01-06 Bruker Daltonics, Inc. Abridged multipole structure for the transport, selection and trapping of ions in a vacuum system
EP2724360B1 (en) * 2011-06-24 2019-07-31 Micromass UK Limited Method and apparatus for generating spectral data
EP2894654B1 (en) * 2012-09-10 2019-05-08 Shimadzu Corporation Ion selection method in ion trap and ion trap device
US10090146B2 (en) * 2014-06-11 2018-10-02 Micromass Uk Limited Ion profiling with a scanning quadrupole mass filter
GB2534892B (en) 2015-02-03 2020-09-09 Auckland Uniservices Ltd An ion mirror, an ion mirror assembly and an ion trap
US10580633B2 (en) * 2017-05-23 2020-03-03 Purdue Research Foundation Systems and methods for conducting neutral loss scans in a single ion trap
DE102019210119A1 (en) 2019-07-09 2021-01-14 BSH Hausgeräte GmbH Household microwave oven with mode variation device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783824A (en) * 1995-04-03 1998-07-21 Hitachi, Ltd. Ion trapping mass spectrometry apparatus
US20050127290A1 (en) * 2003-12-16 2005-06-16 Hitachi High-Technologies Corporation Mass Spectrometer
WO2006075182A2 (en) * 2005-01-17 2006-07-20 Micromass Uk Limited Mass spectrometer
WO2007060436A2 (en) * 2005-11-25 2007-05-31 Micromass Uk Limited Mass spectrometer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6653296A (en) 1995-08-11 1997-03-12 Mds Health Group Limited Spectrometer with axial field
US6107628A (en) * 1998-06-03 2000-08-22 Battelle Memorial Institute Method and apparatus for directing ions and other charged particles generated at near atmospheric pressures into a region under vacuum
US6791078B2 (en) * 2002-06-27 2004-09-14 Micromass Uk Limited Mass spectrometer
US6992283B2 (en) * 2003-06-06 2006-01-31 Micromass Uk Limited Mass spectrometer
GB0416288D0 (en) 2004-07-21 2004-08-25 Micromass Ltd Mass spectrometer
US7456396B2 (en) * 2004-08-19 2008-11-25 Thermo Finnigan Llc Isolating ions in quadrupole ion traps for mass spectrometry

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783824A (en) * 1995-04-03 1998-07-21 Hitachi, Ltd. Ion trapping mass spectrometry apparatus
US20050127290A1 (en) * 2003-12-16 2005-06-16 Hitachi High-Technologies Corporation Mass Spectrometer
WO2006075182A2 (en) * 2005-01-17 2006-07-20 Micromass Uk Limited Mass spectrometer
WO2007060436A2 (en) * 2005-11-25 2007-05-31 Micromass Uk Limited Mass spectrometer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COLLINGS B A ET AL: "Observation of higher order quadrupole excitation frequencies in a linear ion trap", JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, ELSEVIER SCIENCE INC., NEW YORK, NY, US, vol. 11, no. 11, November 2000 (2000-11-01), pages 1016 - 1022, XP004224837, ISSN: 1044-0305 *
HASHIMOTO ET AL: "Mass Selective Ejection by Axial Resonant Excitation from a Linear Ion Trap", JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, ELSEVIER SCIENCE INC, US, vol. 17, no. 5, May 2006 (2006-05-01), pages 685 - 690, XP005412910, ISSN: 1044-0305 *
WELLING M ET AL: "Ion/molecule reactions, mass spectrometry and optical spectroscopy in a linear ion trap", INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 172, no. 1-2, 1998, pages 95 - 114, XP004109270, ISSN: 1387-3806 *

Also Published As

Publication number Publication date
US8022358B2 (en) 2011-09-20
US20080302958A1 (en) 2008-12-11
WO2007072038A2 (en) 2007-06-28
EP1964155B1 (en) 2013-03-27
EP2506288B1 (en) 2016-12-14
GB0625621D0 (en) 2007-01-31
GB2436201B (en) 2008-02-27
EP1964155A2 (en) 2008-09-03
GB2436201A (en) 2007-09-19
GB0526043D0 (en) 2006-02-01
EP2506288A1 (en) 2012-10-03

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