WO2007059950A3 - Dry powder pharmaceutical formulations of purine a2a agonists - Google Patents

Dry powder pharmaceutical formulations of purine a2a agonists Download PDF

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Publication number
WO2007059950A3
WO2007059950A3 PCT/EP2006/011211 EP2006011211W WO2007059950A3 WO 2007059950 A3 WO2007059950 A3 WO 2007059950A3 EP 2006011211 W EP2006011211 W EP 2006011211W WO 2007059950 A3 WO2007059950 A3 WO 2007059950A3
Authority
WO
WIPO (PCT)
Prior art keywords
dry powder
purine
agonists
pharmaceutical formulations
powder pharmaceutical
Prior art date
Application number
PCT/EP2006/011211
Other languages
French (fr)
Other versions
WO2007059950A2 (en
Inventor
Roger Barrett
Richard Peter Charles Cousins
Kay Holton
Philip John Neale
Original Assignee
Glaxo Group Ltd
Roger Barrett
Richard Peter Charles Cousins
Kay Holton
Philip John Neale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Roger Barrett, Richard Peter Charles Cousins, Kay Holton, Philip John Neale filed Critical Glaxo Group Ltd
Publication of WO2007059950A2 publication Critical patent/WO2007059950A2/en
Publication of WO2007059950A3 publication Critical patent/WO2007059950A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a pharmaceutical dry powder composition comprising (i) a compound of formula (I): or a salt or solvate thereof in solid particulate form; (ii) one or more pharmaceutically acceptable particulate carriers; and (iii) one or more stabilising excipients of potential use in the treatment of inflammatory diseases such as asthma and chronic obstructive pulmonary disease.
PCT/EP2006/011211 2005-11-23 2006-11-21 Dry powder pharmaceutical formulations of purine a2a agonists WO2007059950A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0523778.9 2005-11-23
GBGB0523778.9A GB0523778D0 (en) 2005-11-23 2005-11-23 Novel method

Publications (2)

Publication Number Publication Date
WO2007059950A2 WO2007059950A2 (en) 2007-05-31
WO2007059950A3 true WO2007059950A3 (en) 2007-08-02

Family

ID=35601004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/011211 WO2007059950A2 (en) 2005-11-23 2006-11-21 Dry powder pharmaceutical formulations of purine a2a agonists

Country Status (2)

Country Link
GB (1) GB0523778D0 (en)
WO (1) WO2007059950A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005116037A1 (en) * 2004-05-24 2005-12-08 Glaxo Group Limited Purine derivative
WO2007009757A1 (en) * 2005-07-19 2007-01-25 Glaxo Group Limited Purine derivatives as agonists of the adenosine a2a receptor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005116037A1 (en) * 2004-05-24 2005-12-08 Glaxo Group Limited Purine derivative
WO2007009757A1 (en) * 2005-07-19 2007-01-25 Glaxo Group Limited Purine derivatives as agonists of the adenosine a2a receptor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARLENE A JACOBSEN: "Adenosine receptor agonists", EXPERT OPINION ON THERAPEUTIC PATENTS, ASHLEY PUBLICATIONS, GB, vol. 12, no. 4, 2002, pages 489 - 501, XP002415535, ISSN: 1354-3776 *

Also Published As

Publication number Publication date
WO2007059950A2 (en) 2007-05-31
GB0523778D0 (en) 2006-01-04

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