WO2007059328A3 - Selective molecular transport through modified disc shunt - Google Patents

Selective molecular transport through modified disc shunt Download PDF

Info

Publication number
WO2007059328A3
WO2007059328A3 PCT/US2006/044795 US2006044795W WO2007059328A3 WO 2007059328 A3 WO2007059328 A3 WO 2007059328A3 US 2006044795 W US2006044795 W US 2006044795W WO 2007059328 A3 WO2007059328 A3 WO 2007059328A3
Authority
WO
WIPO (PCT)
Prior art keywords
disc
vertebral bodies
bonding
molecular transport
selective molecular
Prior art date
Application number
PCT/US2006/044795
Other languages
French (fr)
Other versions
WO2007059328A2 (en
Inventor
James E Kemler
Jeffrey E Yeung
Original Assignee
James E Kemler
Jeffrey E Yeung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by James E Kemler, Jeffrey E Yeung filed Critical James E Kemler
Publication of WO2007059328A2 publication Critical patent/WO2007059328A2/en
Publication of WO2007059328A3 publication Critical patent/WO2007059328A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3478—Endoscopic needles, e.g. for infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7061—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant for stabilising vertebrae or discs by improving the condition of their tissues, e.g. using implanted medication or fluid exchange
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00261—Discectomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient

Abstract

The disc contains no blood vessels. Nutrients and oxygen essential to disc cells are diffused from adjacent vertebral bodies into the disc. As we age, calcified layers form between the disc and vertebral bodies, blocking diffusion. The disc begins to starve and flatten. The weight shifts abnormally from disc to the facet joints causing strain and pain. Hydrophilic or charged groups are proposed bonding to disc shunts to facilitate the exchange between the avascular disc and bodily circulation. In addition, bonding of cleavable hydrophobic groups delays or hinders transport to minimize infiltration of immunoglobulins or cytokines into the immuno-isolated disc.
PCT/US2006/044795 2005-11-19 2006-11-17 Selective molecular transport through modified disc shunt WO2007059328A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73845005P 2005-11-19 2005-11-19
US60/738,450 2005-11-19

Publications (2)

Publication Number Publication Date
WO2007059328A2 WO2007059328A2 (en) 2007-05-24
WO2007059328A3 true WO2007059328A3 (en) 2008-01-31

Family

ID=38049322

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/044795 WO2007059328A2 (en) 2005-11-19 2006-11-17 Selective molecular transport through modified disc shunt

Country Status (1)

Country Link
WO (1) WO2007059328A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017825A2 (en) * 2000-08-28 2002-03-07 Disc Dynamics, Inc. Intervertebral disc prosthesis
US20040024400A1 (en) * 1994-05-27 2004-02-05 Michelson Gary Karlin Method for the delivery of electrical current to promote bone growth between adjacent bone masses
WO2004101015A2 (en) * 2003-05-07 2004-11-25 Aleeva Medical, Inc. Device for treating back pain by re-establishing the exchange of nutrient & waste

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040024400A1 (en) * 1994-05-27 2004-02-05 Michelson Gary Karlin Method for the delivery of electrical current to promote bone growth between adjacent bone masses
WO2002017825A2 (en) * 2000-08-28 2002-03-07 Disc Dynamics, Inc. Intervertebral disc prosthesis
WO2004101015A2 (en) * 2003-05-07 2004-11-25 Aleeva Medical, Inc. Device for treating back pain by re-establishing the exchange of nutrient & waste

Also Published As

Publication number Publication date
WO2007059328A2 (en) 2007-05-24

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