WO2007056854A1 - Method of expanding double negative t cells - Google Patents
Method of expanding double negative t cells Download PDFInfo
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- WO2007056854A1 WO2007056854A1 PCT/CA2006/001870 CA2006001870W WO2007056854A1 WO 2007056854 A1 WO2007056854 A1 WO 2007056854A1 CA 2006001870 W CA2006001870 W CA 2006001870W WO 2007056854 A1 WO2007056854 A1 WO 2007056854A1
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- cells
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- tumor
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Abstract
Description
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Priority Applications (5)
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US12/093,492 US9018004B2 (en) | 2005-11-18 | 2006-11-20 | Method of expanding double negative T cells |
EP06804734A EP1948788A4 (en) | 2005-11-18 | 2006-11-20 | Method of expanding double negative t cells |
CN2006800431167A CN101313061B (en) | 2005-11-18 | 2006-11-20 | Method of expanding double negative T cells |
CA2629532A CA2629532C (en) | 2005-11-18 | 2006-11-20 | Method of expanding double negative t cells |
US14/674,548 US9925220B2 (en) | 2005-11-18 | 2015-03-31 | Method of expanding double negative T cells |
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US73775905P | 2005-11-18 | 2005-11-18 | |
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US12/093,492 A-371-Of-International US9018004B2 (en) | 2005-11-18 | 2006-11-20 | Method of expanding double negative T cells |
US14/674,548 Continuation US9925220B2 (en) | 2005-11-18 | 2015-03-31 | Method of expanding double negative T cells |
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EP (1) | EP1948788A4 (en) |
CN (1) | CN101313061B (en) |
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WO (1) | WO2007056854A1 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009103157A1 (en) * | 2008-02-22 | 2009-08-27 | University Health Network | Mfap4 as a marker for regulatory cells and anti-cancer cells |
WO2016023134A1 (en) | 2014-08-15 | 2016-02-18 | University Health Network | Immunotherapy for the treatment of cancer |
JP2016077185A (en) * | 2014-10-14 | 2016-05-16 | 学校法人 聖マリアンナ医科大学 | PRODUCTION METHOD AND MEDICINE OF γδT CELLS |
WO2016179684A1 (en) * | 2015-05-11 | 2016-11-17 | University Health Network | Method for expansion of double negative regulatory t cells |
WO2020124248A1 (en) * | 2018-12-19 | 2020-06-25 | University Health Network | Production and therapeutic use of off-the-shelf double negative t cells |
WO2020244345A1 (en) * | 2019-06-04 | 2020-12-10 | 北京医明佳和生物科技有限公司 | Purified double negative t cell and preparation and use thereof |
Families Citing this family (11)
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CN105658784B (en) * | 2013-12-18 | 2018-12-11 | 东洋制罐集团控股株式会社 | Culture vessel, the cultural method of lymphocyte, the manufacturing method of culture vessel and immobilization device |
CN104109653B (en) * | 2014-06-12 | 2017-06-13 | 浙江瑞顺生物技术有限公司 | Method using human peripheral DNT cells are expanded without animal blood serum cultivating system on a large scale |
CN104789595A (en) * | 2015-04-20 | 2015-07-22 | 范国煌 | Construction method of chimeric antigen receptor double-negative T cell |
EA201890013A1 (en) * | 2015-06-09 | 2018-07-31 | Лимфакт - Лимфоцит Активэйшн Текнолоджис, С.А. | METHODS FOR OBTAINING TCR GAMMA DELTAT-CELLS |
US10201572B2 (en) * | 2015-09-15 | 2019-02-12 | University Health Network | Combination therapy with double negative T-cells |
CN105483083B (en) * | 2016-01-20 | 2018-10-23 | 北京医明佳和生物科技有限公司 | The conversion amplification method of double negative t cells |
US20210046119A1 (en) * | 2018-04-20 | 2021-02-18 | Children's National Medical Center | Fixed ratio ex vivo activated mixed lymphocyte products for use in the treatment of cancer |
CN111374989B (en) * | 2020-03-16 | 2022-04-19 | 中山大学附属第五医院 | Medicine for treating inflammatory bowel disease |
CN113528434A (en) * | 2020-04-20 | 2021-10-22 | 瑞创生物技术有限公司 | Universal efficient in-vitro amplification method for clinical multiple-time transfusion of allogeneic DNT cells |
CN112063584A (en) * | 2020-11-14 | 2020-12-11 | 北京原能细胞生物科技有限公司 | Progressive separation and culture method of tumor-specific TIL and DNT cells |
CN116083359A (en) * | 2021-11-05 | 2023-05-09 | 瑞创生物技术有限公司 | Method for large-scale in-vitro amplification of double negative T cells rich in Tscm and Tcm |
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US5985656A (en) * | 1986-06-12 | 1999-11-16 | The Board Of Trustees Of The Leland Stanford Junior University | Suppressor and progenitor cells |
US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
NZ237669A (en) * | 1990-04-13 | 1992-08-26 | Res Dev Foundation | T-cell proteins expressed in t-cell development and their preparation |
US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
EP1127107B1 (en) | 1998-11-04 | 2009-01-21 | Therapure Biopharma Inc. | Methods for the production of tcr gamma delta t cells |
US20030157060A1 (en) * | 2000-04-03 | 2003-08-21 | Bell David N | Production of tcr gamma delta t cells |
AU2001248162B2 (en) | 2000-04-03 | 2007-02-01 | Hemosol Lp. | Production of TcR gamma delta T cells |
US6953576B2 (en) | 2000-08-21 | 2005-10-11 | University Health Network | Method of modulating tumor immunity |
US20030170238A1 (en) * | 2002-03-07 | 2003-09-11 | Gruenberg Micheal L. | Re-activated T-cells for adoptive immunotherapy |
-
2006
- 2006-11-20 CA CA2629532A patent/CA2629532C/en active Active
- 2006-11-20 CN CN2006800431167A patent/CN101313061B/en active Active
- 2006-11-20 WO PCT/CA2006/001870 patent/WO2007056854A1/en active Application Filing
- 2006-11-20 EP EP06804734A patent/EP1948788A4/en not_active Withdrawn
- 2006-11-20 US US12/093,492 patent/US9018004B2/en active Active
-
2015
- 2015-03-31 US US14/674,548 patent/US9925220B2/en active Active
Non-Patent Citations (5)
Cited By (13)
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WO2009103157A1 (en) * | 2008-02-22 | 2009-08-27 | University Health Network | Mfap4 as a marker for regulatory cells and anti-cancer cells |
US10517937B2 (en) | 2014-08-15 | 2019-12-31 | University Health Network | Immunotherapy for the treatment of cancer |
WO2016023134A1 (en) | 2014-08-15 | 2016-02-18 | University Health Network | Immunotherapy for the treatment of cancer |
JP2017527551A (en) * | 2014-08-15 | 2017-09-21 | ユニバーシティ・ヘルス・ネットワーク | Immunotherapy for cancer treatment |
JP2016077185A (en) * | 2014-10-14 | 2016-05-16 | 学校法人 聖マリアンナ医科大学 | PRODUCTION METHOD AND MEDICINE OF γδT CELLS |
EP3208329A4 (en) * | 2014-10-14 | 2018-05-23 | St. Marianna University School of Medicine | Method for producing gamma-delta t cells, and pharmaceutical |
WO2016179684A1 (en) * | 2015-05-11 | 2016-11-17 | University Health Network | Method for expansion of double negative regulatory t cells |
US11534460B2 (en) | 2015-05-11 | 2022-12-27 | University Health Network | Method for expansion of double negative regulatory T cells |
WO2020124248A1 (en) * | 2018-12-19 | 2020-06-25 | University Health Network | Production and therapeutic use of off-the-shelf double negative t cells |
EP3898950A4 (en) * | 2018-12-19 | 2022-10-05 | University Health Network | Production and therapeutic use of off-the-shelf double negative t cells |
WO2020244345A1 (en) * | 2019-06-04 | 2020-12-10 | 北京医明佳和生物科技有限公司 | Purified double negative t cell and preparation and use thereof |
JP2022535881A (en) * | 2019-06-04 | 2022-08-10 | 北京医明佳和生物科技有限公司 | Purified double-negative T cells and their preparation and application |
JP7338903B2 (en) | 2019-06-04 | 2023-09-05 | 北京医明佳和生物科技有限公司 | Purified double-negative T cells and their preparation and application |
Also Published As
Publication number | Publication date |
---|---|
US9925220B2 (en) | 2018-03-27 |
US20090098095A1 (en) | 2009-04-16 |
CN101313061A (en) | 2008-11-26 |
EP1948788A1 (en) | 2008-07-30 |
CN101313061B (en) | 2013-05-15 |
EP1948788A4 (en) | 2009-07-01 |
US9018004B2 (en) | 2015-04-28 |
US20160045550A1 (en) | 2016-02-18 |
CA2629532A1 (en) | 2007-05-24 |
CA2629532C (en) | 2016-08-09 |
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