WO2007039314A3 - Plants with increased hyaluronan production - Google Patents

Plants with increased hyaluronan production Download PDF

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Publication number
WO2007039314A3
WO2007039314A3 PCT/EP2006/009773 EP2006009773W WO2007039314A3 WO 2007039314 A3 WO2007039314 A3 WO 2007039314A3 EP 2006009773 W EP2006009773 W EP 2006009773W WO 2007039314 A3 WO2007039314 A3 WO 2007039314A3
Authority
WO
WIPO (PCT)
Prior art keywords
plants
hyaluronan
plant cells
increased
preparing
Prior art date
Application number
PCT/EP2006/009773
Other languages
French (fr)
Other versions
WO2007039314A2 (en
Inventor
Claus Frohberg
Bernd Essigmann
Original Assignee
Bayer Cropscience Ag
Claus Frohberg
Bernd Essigmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag, Claus Frohberg, Bernd Essigmann filed Critical Bayer Cropscience Ag
Priority to US12/089,270 priority Critical patent/US10428341B2/en
Priority to EP06806148.0A priority patent/EP1951878B1/en
Priority to PL06806148T priority patent/PL1951878T3/en
Priority to CN200680035690.8A priority patent/CN101273135B/en
Priority to DK06806148.0T priority patent/DK1951878T3/en
Priority to AU2006298961A priority patent/AU2006298961B2/en
Priority to ES06806148.0T priority patent/ES2536925T3/en
Priority to CA2624592A priority patent/CA2624592C/en
Priority to BRPI0616845A priority patent/BRPI0616845A8/en
Priority to JP2008533951A priority patent/JP2009509555A/en
Publication of WO2007039314A2 publication Critical patent/WO2007039314A2/en
Publication of WO2007039314A3 publication Critical patent/WO2007039314A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1096Transferases (2.) transferring nitrogenous groups (2.6)

Abstract

The present invention relates to plant cells and plants which synthesize an increased amount of hyaluronan, and to methods for preparing such plants, and also to methods for preparing hyaluronan with the aid of these plant cells or plants. Here, plant cells or genetically modified plants according to the invention have hyaluronan synthase activity and additionally an increased glutamine:fructose 6-phosphate amidotransferase (GFAT) activity compared to wild-type plant cells or wild-type plants. The present invention furthermore relates to the use of plants having increased hyaluronan synthesis for preparing hyaluronan and food or feedstuff containing hyaluronan.
PCT/EP2006/009773 2005-10-05 2006-10-05 Plants with increased hyaluronan production WO2007039314A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US12/089,270 US10428341B2 (en) 2005-10-05 2006-10-05 Transgenic potato plants with increased hyaluronan production
EP06806148.0A EP1951878B1 (en) 2005-10-05 2006-10-05 Plants with increased hyaluronan production
PL06806148T PL1951878T3 (en) 2005-10-05 2006-10-05 Plants with increased hyaluronan production
CN200680035690.8A CN101273135B (en) 2005-10-05 2006-10-05 Plants with increased hyaluronan production
DK06806148.0T DK1951878T3 (en) 2005-10-05 2006-10-05 Plants with increased hyaluronanproduktion
AU2006298961A AU2006298961B2 (en) 2005-10-05 2006-10-05 Plants with increased hyaluronan production
ES06806148.0T ES2536925T3 (en) 2005-10-05 2006-10-05 Plants with increased hyaluronan production
CA2624592A CA2624592C (en) 2005-10-05 2006-10-05 Gfat-expressing plants with increased hyaluronan production
BRPI0616845A BRPI0616845A8 (en) 2005-10-05 2006-10-05 PLANTS WITH INCREASED HIALURONAN PRODUCTION
JP2008533951A JP2009509555A (en) 2005-10-05 2006-10-05 Plant II with increased hyaluronic acid production

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05090279.0 2005-10-05
EP05090279 2005-10-05
US72538805P 2005-10-11 2005-10-11
US60/725,388 2005-10-11

Publications (2)

Publication Number Publication Date
WO2007039314A2 WO2007039314A2 (en) 2007-04-12
WO2007039314A3 true WO2007039314A3 (en) 2007-08-16

Family

ID=37906526

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/009773 WO2007039314A2 (en) 2005-10-05 2006-10-05 Plants with increased hyaluronan production

Country Status (7)

Country Link
US (1) US10428341B2 (en)
EP (1) EP1951878B1 (en)
JP (1) JP2009509555A (en)
AU (1) AU2006298961B2 (en)
CA (1) CA2624592C (en)
PL (1) PL1951878T3 (en)
WO (1) WO2007039314A2 (en)

Cited By (4)

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US9574201B2 (en) 2010-06-09 2017-02-21 Bayer Cropscience Nv Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering
US9593317B2 (en) 2010-06-09 2017-03-14 Bayer Cropscience Nv Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering

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