WO2007017868A1 - Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials - Google Patents

Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials Download PDF

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Publication number
WO2007017868A1
WO2007017868A1 PCT/IL2006/000912 IL2006000912W WO2007017868A1 WO 2007017868 A1 WO2007017868 A1 WO 2007017868A1 IL 2006000912 W IL2006000912 W IL 2006000912W WO 2007017868 A1 WO2007017868 A1 WO 2007017868A1
Authority
WO
WIPO (PCT)
Prior art keywords
vial
flex members
liquid drug
snap fitting
retention
Prior art date
Application number
PCT/IL2006/000912
Other languages
French (fr)
Inventor
Freddy Zinger
Igor Denenburg
Moshe Gilboa
Original Assignee
Medimop Medical Projects Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimop Medical Projects Ltd filed Critical Medimop Medical Projects Ltd
Priority to AT06766219T priority Critical patent/ATE529088T1/en
Priority to US12/063,176 priority patent/US8070739B2/en
Priority to EP20060766219 priority patent/EP1919432B1/en
Priority to JP2008525719A priority patent/JP2009504230A/en
Priority to DK06766219T priority patent/DK1919432T3/en
Publication of WO2007017868A1 publication Critical patent/WO2007017868A1/en
Priority to IL188974A priority patent/IL188974A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2065—Connecting means having aligning and guiding means

Definitions

  • the invention pertains to liquid drug transfer devices for snap fitting onto medicinal vials.
  • Medimop Medical Projects Ltd., Ra'anana, Israel supply liquid drug transfer devices for use with medicinal vials containing liquid or powder drug contents and having a vial opening stopped by a typically rubber stopper. Vials are typically available in 13/14mm and 20mm standard sizes, and often contain expensive drugs.
  • the liquid drug transfer devices include inter alia vial adapters with single lumen puncturing spikes, vented vial adapters with dual lumen puncturing spikes, fluid control devices illustrated and described in commonly owned PCT International Publication No.
  • liquid drug transfer devices are used by both professional users and also home users, for example, young users, visually impaired users, infirm users, and the like, for self-drug administration purposes in the home.
  • the liquid drug transfer devices include a plastic molded vial adapter with a generally cylindrical skirt for telescopically slidingly receiving a vial opening therein, an integrally formed hollow puncturing spike for puncturing the viaKs stopper and having at least one flow aperture towards the puncturing spike's tip for accessing the vial ' s interior, and at least one access port in flow communication with the puncturing spike.
  • the skirts typically include four or six flex members including at least two non-adjacent vial retention flex members with at least partially circumferentially extending inwardly protruding vial retention ribs for snap fitting over a vial opening for vial retention purposes.
  • the vial retention flex members are designed such that vial adapters cannot be released from a medicinal vial after being snap fitted thereon for sterilization purposes.
  • Flex members not employed for vial retention purposes have smooth inner surfaces for bearing against a vial opening for stabilization purposes.
  • Such vial stabilization flex members are typically of the same length as their counterpart vial retention flex members but maybe shorter, for example, as shown in US Patent Application Publication No. 2003/0199S47 to Akerlund et al. Misalignment of a liquid drug transfer device with respect to a vial results in puncturing difficulties and in some instances its vial adapter's puncturing spike's tip being embedded in the vial's stopper, thereby precluding flow communication with the vial ' s interior.
  • the present invention is directed towards liquid drug transfer devices including a vial adapter designed for failsafe correct snap fitting on a medicinal vial for ensuring flow communication with the vial's interior.
  • the vial adapters include at least two non-adjacent vial retention flex members for snap fitting on a vial opening for vial retention purposes and at least two non-adjacent vial guidance flex members longer than their counterpart vial retention flex members for guiding a vial adapter with respect to a vial prior to snap fitting the vial adapter thereon.
  • the vial guidance flex members are designed such that they assist a user to correctly co-axially align a liquid drug delivery device with respect to a vial prior to the former's puncturing spike touches the latter 's stopper.
  • the vial guidance flex members have the tendency to cause a user to more cautiously approach a snap fitting procedure, thereby considerably assisting in correct snap fittings.
  • Fig. 1 is a pictorial view of a first preferred embodiment of a liquid drug transfer device with a vial adapter for failsafe correct snap fitting on a medicinal vial;
  • Fig. 2 is a longitudinal cross section of the liquid drug transfer device and the medicinal vial along line A-A in Figure 1;
  • Fig. 3A is a longitudinal cross section demonstrating a liquid drug transfer device off centered with respect to the medicinal vial
  • Fig. 3B is a longitudinal cross section demonstrating a liquid drug transfer device angled with respect to the medicinal vial;
  • Fig. 3C is a longitudinal cross section of the liquid drug transfer device co-axially aligned with respect to the medicinal vial for failsafe correct snap fitting thereon;
  • Fig. 3D is a longitudinal cross section of the liquid drug transfer device slightly depressed toward the medicinal vial;
  • Fig. 3E is a longitudinal cross section of the liquid drug transfer device snap fitted on the medicinal vial and in flow communication with the vial's interior;
  • Fig. 4 is a pictorial view of a second preferred embodiment of a liquid drug transfer device with a vented vial adapter for failsafe correct snap fitting on a medicinal vial;
  • Fig. 5 is a pictorial view of a MIXJECT"" fluid control device with a vial adapter for failsafe correct snap fitting on a medicinal vial.
  • Figures 1 and 2 show a liquid drug transfer device 10 for failsafe correct snap fitting on a conventional medicinal vial 11.
  • the vial 11 has a longitudinal axis 12, a bottle portion 13 containing a liquid drug 14, a vial opening 16, and a narrow neck 17 intermediate the bottle portion 13 and the vial opening 16.
  • the vial opening 16 is stopped by a typically rubber stopper 18.
  • the stopper 18 has a circular head 19 and a downward depending tubular section 21 with a blind bore 22 having a cross section area Al in a transverse direction to the longitudinal axis 12.
  • the vial 11 is hermetically sealed by an aluminum band 23 with a rim 24 having an external diameter Dl, and an axially directed peripheral surface 26, and exposing a raised central area 27 of the stopper 18.
  • the stopper's central area 27 has a cross section area A2 in a transverse direction to the longitudinal axis 12 where A2>A1.
  • the design feature A2>A1 contributes to misalignment of a vial adapter with respect to a vial for flow communication purposes because users are under the mistaken impression that they have a larger target area for puncturing purposes than they have in practice.
  • the liquid drug transfer device 10 includes a plastic molded vial adapter 30 having a longitudinal axis 31, and an upright female Luer connector 32 for receiving a syringe (not shown) and integrally formed with the vial adapter 30.
  • the vial adapter 30 includes a top wall 33 transverse to the longitudinal axis 31 , and a substantially cylindrical skirt 34 for telescopically slidingly receiving the vial opening 16 therein.
  • the skirt 34 includes three non-adjacent axially directed vial retention flex members 36 and three non-adjacent axially directed vial guidance flex members 37 resiliently elastically attached to the top wall 33.
  • the vial adapter 30 includes an integrally formed hollow puncturing spike 38 in flow communication with the female Luer connector 32.
  • the puncturing spike 38 has a tip 39 with a flow aperture 41 theretowards.
  • the vial retention flex members 36 have inside surfaces 36A and outwardly taper to flex member tips 36B with an internal diameter D2>D 1 and having a length Ll relative to the top wall 33.
  • the inward surfaces 36A are provided with circumferentially extending inwardly protruding vial retention ribs 36C for snap fitting over the vial opening 16 for vial retention purposes.
  • the puncturing spike's tip 39 downwardly extends slightly past the vial retention ribs 36C such that the puncturing spike's flow aperture 41 resides in a vial's blind bore 22 on snap fitting the liquid rug transfer device 10 on a vial 11.
  • the vial guidance flex members 37 have straight inside surfaces 37A and extend to flex member tips 37B with an internal diameter D3 where D2>D3>D1 and having a length L2>L1 relative to the top wall 33.
  • the flex member tips 37B downwardly extend beyond the flex member tips 36B such that the former contact a band's rim 24 before the puncturing spike's tip 39 contacts the vial ' s stopper 18 for positively guiding the liquid drug delivery device 10 in concentric alignment with the vial 11.
  • Figure 4 shows a liquid drug transfer device similar 50 in construction and use as the liquid drug transfer device 10 and differing therefrom insofar that the former is vented and includes a vial adapter 51 with two non-adjacent axially directed vial retention flex members 36 and two non-adjacent axially directed vial guidance flex members 37.
  • Figure 5 shows a MIXJECT 1 " fluid control device 60 with a detachable vial adapter ol similar to the vial adapter 30 for failsafe correct snap fitting on a medicinal vial.

Abstract

Liquid drug transfer devices including a vial adapter designed for failsafe correct snap fitting on a medicinal vial for ensuring flow communication with the vial's interior. The vial adapters include at least two non-adjacent vial retention flex members for snap fitting over a vial opening for vial retention purposes and at least two non-adjacent vial guidance flex members longer than their counterpart vial retention flex members for guiding a vial adapter with respect to a vial prior to snap fittnig the vial adapter thereon.

Description

LIQUID DRUG TRANSFER DEVICES FOR FAILSAFE CORRECT SNAP FITTING ONTO MEDICINAL VIALS
Field of the Invention
The invention pertains to liquid drug transfer devices for snap fitting onto medicinal vials.
Background of the Invention
Medimop Medical Projects Ltd., Ra'anana, Israel (www.medimop.com) supply liquid drug transfer devices for use with medicinal vials containing liquid or powder drug contents and having a vial opening stopped by a typically rubber stopper. Vials are typically available in 13/14mm and 20mm standard sizes, and often contain expensive drugs. The liquid drug transfer devices include inter alia vial adapters with single lumen puncturing spikes, vented vial adapters with dual lumen puncturing spikes, fluid control devices illustrated and described in commonly owned PCT International Publication No. WO96/29113, MIX2VIAL"" fluid control devices illustrated and described in commonly owned US Patent 6,558,365 to Zinger et al., in-line MIXJECT''0 fluid control devices illustrated and described in commonly owned PCT International Publication No. WO 2005/105014, and the like. The liquid drug transfer devices are used by both professional users and also home users, for example, young users, visually impaired users, infirm users, and the like, for self-drug administration purposes in the home.
The liquid drug transfer devices include a plastic molded vial adapter with a generally cylindrical skirt for telescopically slidingly receiving a vial opening therein, an integrally formed hollow puncturing spike for puncturing the viaKs stopper and having at least one flow aperture towards the puncturing spike's tip for accessing the vial's interior, and at least one access port in flow communication with the puncturing spike. The skirts typically include four or six flex members including at least two non-adjacent vial retention flex members with at least partially circumferentially extending inwardly protruding vial retention ribs for snap fitting over a vial opening for vial retention purposes. The vial retention flex members are designed such that vial adapters cannot be released from a medicinal vial after being snap fitted thereon for sterilization purposes. Flex members not employed for vial retention purposes have smooth inner surfaces for bearing against a vial opening for stabilization purposes. Such vial stabilization flex members are typically of the same length as their counterpart vial retention flex members but maybe shorter, for example, as shown in US Patent Application Publication No. 2003/0199S47 to Akerlund et al. Misalignment of a liquid drug transfer device with respect to a vial results in puncturing difficulties and in some instances its vial adapter's puncturing spike's tip being embedded in the vial's stopper, thereby precluding flow communication with the vial's interior. In such instances, notw ithstanding that a vial contains a full dosage of medicament, it is necessarily discarded. It has been long recognized that inaccurate snap fitting of vial adapters on vials can be at least partially contributed to a problematic design feature of medicinal vials described hereinafter. Professional users of liquid drug delivery devices are generally aware of this design feature but are still prone to inaccurately snap fit a vial adapter on a vial due to time pressure, and the like. Home users of liquid drug delivery devices are often not even aware of the design feature and are therefore even more prone to inaccurately snap fit a vial adapter on a vial despite their best efforts.
Summary of the Invention
The present invention is directed towards liquid drug transfer devices including a vial adapter designed for failsafe correct snap fitting on a medicinal vial for ensuring flow communication with the vial's interior. The vial adapters include at least two non-adjacent vial retention flex members for snap fitting on a vial opening for vial retention purposes and at least two non-adjacent vial guidance flex members longer than their counterpart vial retention flex members for guiding a vial adapter with respect to a vial prior to snap fitting the vial adapter thereon. The vial guidance flex members are designed such that they assist a user to correctly co-axially align a liquid drug delivery device with respect to a vial prior to the former's puncturing spike touches the latter 's stopper. Moreover, the vial guidance flex members have the tendency to cause a user to more cautiously approach a snap fitting procedure, thereby considerably assisting in correct snap fittings.
Brief Description of the Drawings
In order to understand the invention and to see how it can be carried out in practice, preferred embodiments will now be described, by way of non-limiting examples only, with reference to the accompanying drawings in which similar parts are likewise numbered, and in which:
Fig. 1 is a pictorial view of a first preferred embodiment of a liquid drug transfer device with a vial adapter for failsafe correct snap fitting on a medicinal vial;
Fig. 2 is a longitudinal cross section of the liquid drug transfer device and the medicinal vial along line A-A in Figure 1;
Fig. 3A is a longitudinal cross section demonstrating a liquid drug transfer device off centered with respect to the medicinal vial; Fig. 3B is a longitudinal cross section demonstrating a liquid drug transfer device angled with respect to the medicinal vial;
Fig. 3C is a longitudinal cross section of the liquid drug transfer device co-axially aligned with respect to the medicinal vial for failsafe correct snap fitting thereon; Fig. 3D is a longitudinal cross section of the liquid drug transfer device slightly depressed toward the medicinal vial;
Fig. 3E is a longitudinal cross section of the liquid drug transfer device snap fitted on the medicinal vial and in flow communication with the vial's interior; Fig. 4 is a pictorial view of a second preferred embodiment of a liquid drug transfer device with a vented vial adapter for failsafe correct snap fitting on a medicinal vial; and
Fig. 5 is a pictorial view of a MIXJECT"" fluid control device with a vial adapter for failsafe correct snap fitting on a medicinal vial.
Detailed Description of Preferred Embodiments of the Present Invention
Figures 1 and 2 show a liquid drug transfer device 10 for failsafe correct snap fitting on a conventional medicinal vial 11. The vial 11 has a longitudinal axis 12, a bottle portion 13 containing a liquid drug 14, a vial opening 16, and a narrow neck 17 intermediate the bottle portion 13 and the vial opening 16. The vial opening 16 is stopped by a typically rubber stopper 18. The stopper 18 has a circular head 19 and a downward depending tubular section 21 with a blind bore 22 having a cross section area Al in a transverse direction to the longitudinal axis 12. The vial 11 is hermetically sealed by an aluminum band 23 with a rim 24 having an external diameter Dl, and an axially directed peripheral surface 26, and exposing a raised central area 27 of the stopper 18. The stopper's central area 27 has a cross section area A2 in a transverse direction to the longitudinal axis 12 where A2>A1. The design feature A2>A1 contributes to misalignment of a vial adapter with respect to a vial for flow communication purposes because users are under the mistaken impression that they have a larger target area for puncturing purposes than they have in practice.
The liquid drug transfer device 10 includes a plastic molded vial adapter 30 having a longitudinal axis 31, and an upright female Luer connector 32 for receiving a syringe (not shown) and integrally formed with the vial adapter 30. The vial adapter 30 includes a top wall 33 transverse to the longitudinal axis 31 , and a substantially cylindrical skirt 34 for telescopically slidingly receiving the vial opening 16 therein. The skirt 34 includes three non-adjacent axially directed vial retention flex members 36 and three non-adjacent axially directed vial guidance flex members 37 resiliently elastically attached to the top wall 33. The vial adapter 30 includes an integrally formed hollow puncturing spike 38 in flow communication with the female Luer connector 32. The puncturing spike 38 has a tip 39 with a flow aperture 41 theretowards.
The vial retention flex members 36 have inside surfaces 36A and outwardly taper to flex member tips 36B with an internal diameter D2>D 1 and having a length Ll relative to the top wall 33. The inward surfaces 36A are provided with circumferentially extending inwardly protruding vial retention ribs 36C for snap fitting over the vial opening 16 for vial retention purposes. The puncturing spike's tip 39 downwardly extends slightly past the vial retention ribs 36C such that the puncturing spike's flow aperture 41 resides in a vial's blind bore 22 on snap fitting the liquid rug transfer device 10 on a vial 11. The vial guidance flex members 37 have straight inside surfaces 37A and extend to flex member tips 37B with an internal diameter D3 where D2>D3>D1 and having a length L2>L1 relative to the top wall 33. The flex member tips 37B downwardly extend beyond the flex member tips 36B such that the former contact a band's rim 24 before the puncturing spike's tip 39 contacts the vial's stopper 18 for positively guiding the liquid drug delivery device 10 in concentric alignment with the vial 11.
The failsafe correct snap fitting of a liquid drug delivery device 10 on a vial 11 is now described with reference to Figures 3 A to 3E: Users are prone to inaccurately align a liquid drug delivery device 10 with respect to a vial 11 either by off centering the liquid drug delivery device 10 (see Figure 3A) or approaching the vial 11 at an angle (see Figure 3B). The vial guidance flex members 37 assist a user to co-axially align the liquid drug delivery device 10 relative to the vial 11 such that its flex member tips 37B simultaneously contact the band's rim 24 before its puncturing spike's tip 39 contacts the vial's stopper 18 (see Figure 3C). Initial depression of the liquid drug delivery device 10 towards the vial 11 causes the vial guidance flex members 37 to flex slightly outward as they travel along the aluminum band's peripheral surface 26 and the puncturing spike's tip 39 to approach the vial's stopper IS before contacting same at about the same time that the inside surfaces 36B under the vial retention ribs 36C touch the band's rim 24 (see Figure 3D). Continued depression of the liquid drug delivery device 10 towards the vial 11 causes the vial guidance flex members 37 to slide over the band's peripheral surface 19 and the vial retention flex members 36 to snap fit over the vial opening 16 and the flow aperture 41 to be positioned midway along the stopper's blind bore 22 for effecting flow communication with the female Luer connector 32 (see Figure 3E).
Figure 4 shows a liquid drug transfer device similar 50 in construction and use as the liquid drug transfer device 10 and differing therefrom insofar that the former is vented and includes a vial adapter 51 with two non-adjacent axially directed vial retention flex members 36 and two non-adjacent axially directed vial guidance flex members 37.
Figure 5 shows a MIXJECT1" fluid control device 60 with a detachable vial adapter ol similar to the vial adapter 30 for failsafe correct snap fitting on a medicinal vial.
While the invention has been described with respect to a limited number of embodiments, it will be appreciated that many variations, modifications, and other applications of the invention can be made within the scope of the appended claims.

Claims

Claims:
1. Liquid drug transfer device for failsafe correct snap fitting on a medicinal vial having a longitudinal axis and including a bottle portion containing a medicament, a vial opening with a rim and an axially directed peripheral surface and stopped by a stopper, and a narrow neck intermediate the bottle portion and the vial opening, the liquid drug transfer device comprising:
(a) a vial adapter having a longitudinal axis, and including a top wall transverse to said longitudinal axis, a substantially cylindrical skirt of at least four axially directed flex members resiliently elastically attached to said top wall and downwardly depending therefrom for telescopically slidingly receiving the vial opening therein, and a hollow puncturing spike for puncturing the stopper, said puncturing spike having a tip with at least one flow aperture for accessing the vial's interior; and
(b) at least one access port in flow communication with said puncturing spike, characterized in that said at least four flex members include at least two non-adjacent vial retention flex members with at least partially circumferentially extending inwardly protruding vial retention ribs for snap fitting over the vial opening for vial retention purposes, and at least two non-adjacent vial guidance flex members longer than said at least two non-adjacent vial retention flex members relative to said top wall for simultaneously contacting the vial opening's rim for aligning said vial adapter with the vial prior to said snap fitting.
2. The device according to claim 1 wherein said skirt includes three non- adjacent vial retention flex members and three non-adjacent vial guidance flex members.
PCT/IL2006/000912 2005-08-11 2006-08-08 Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials WO2007017868A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AT06766219T ATE529088T1 (en) 2005-08-11 2006-08-08 TRANSFER DEVICES FOR LIQUID MEDICINAL PRODUCTS FOR FAIL-SAFE CORRECT LATCH CONNECTION ON MEDICAL AMPOULES
US12/063,176 US8070739B2 (en) 2005-08-11 2006-08-08 Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials
EP20060766219 EP1919432B1 (en) 2005-08-11 2006-08-08 Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials
JP2008525719A JP2009504230A (en) 2005-08-11 2006-08-08 Liquid drug transfer device that snap-fits accurately and securely into pharmaceutical vials
DK06766219T DK1919432T3 (en) 2005-08-11 2006-08-08 Liquid Medication Transfer Devices for Safe Safe Resting Connection on Medical Vials
IL188974A IL188974A (en) 2005-08-11 2008-01-23 Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70718305P 2005-08-11 2005-08-11
US60/707,183 2005-08-11

Publications (1)

Publication Number Publication Date
WO2007017868A1 true WO2007017868A1 (en) 2007-02-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2006/000912 WO2007017868A1 (en) 2005-08-11 2006-08-08 Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials

Country Status (7)

Country Link
US (1) US8070739B2 (en)
EP (1) EP1919432B1 (en)
JP (1) JP2009504230A (en)
AT (1) ATE529088T1 (en)
DK (1) DK1919432T3 (en)
ES (1) ES2371557T3 (en)
WO (1) WO2007017868A1 (en)

Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
US8435210B2 (en) 2007-04-17 2013-05-07 Medimop Medical Projects Ltd. Fluid control device with manually depressed actuator
US8608723B2 (en) 2009-11-12 2013-12-17 Medimop Medical Projects Ltd. Fluid transfer devices with sealing arrangement
CN103458850A (en) * 2011-04-17 2013-12-18 麦迪麦珀医疗工程有限公司 Liquid drug transfer assembly
WO2014041529A1 (en) 2012-09-13 2014-03-20 Medimop Medical Projects Ltd Telescopic female drug vial adapter
US8684994B2 (en) 2010-02-24 2014-04-01 Medimop Medical Projects Ltd. Fluid transfer assembly with venting arrangement
US8753325B2 (en) 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
US8852145B2 (en) 2010-11-14 2014-10-07 Medimop Medical Projects, Ltd. Inline liquid drug medical device having rotary flow control member
US8905994B1 (en) 2011-10-11 2014-12-09 Medimop Medical Projects, Ltd. Valve assembly for use with liquid container and drug vial
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
WO2015021499A1 (en) * 2013-08-13 2015-02-19 Noble House Group Pty. Ltd. Universal sampling cap
US8979792B2 (en) 2009-11-12 2015-03-17 Medimop Medical Projects Ltd. Inline liquid drug medical devices with linear displaceable sliding flow control member
US8998875B2 (en) 2009-10-01 2015-04-07 Medimop Medical Projects Ltd. Vial assemblage with vial and pre-attached fluid transfer device
USD734868S1 (en) 2012-11-27 2015-07-21 Medimop Medical Projects Ltd. Drug vial adapter with downwardly depending stopper
USD737436S1 (en) 2012-02-13 2015-08-25 Medimop Medical Projects Ltd. Liquid drug reconstitution assembly
US9283324B2 (en) 2012-04-05 2016-03-15 Medimop Medical Projects, Ltd Fluid transfer devices having cartridge port with cartridge ejection arrangement
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
USD765837S1 (en) 2013-08-07 2016-09-06 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
USD767124S1 (en) 2013-08-07 2016-09-20 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
US9795536B2 (en) 2012-08-26 2017-10-24 Medimop Medical Projects, Ltd. Liquid drug transfer devices employing manual rotation for dual flow communication step actuations
USD801522S1 (en) 2015-11-09 2017-10-31 Medimop Medical Projects Ltd. Fluid transfer assembly
US9801786B2 (en) 2013-04-14 2017-10-31 Medimop Medical Projects Ltd. Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
US9943463B2 (en) 2013-05-10 2018-04-17 West Pharma. Services IL, Ltd. Medical devices including vial adapter with inline dry drug module
USD832430S1 (en) 2016-11-15 2018-10-30 West Pharma. Services IL, Ltd. Dual vial adapter assemblage
US10278897B2 (en) 2015-11-25 2019-05-07 West Pharma. Services IL, Ltd. Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
US10285907B2 (en) 2015-01-05 2019-05-14 West Pharma. Services IL, Ltd. Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
WO2019219383A1 (en) * 2018-05-17 2019-11-21 Becton Dickinson France Connector for connecting a medical injection device to a container
US10646404B2 (en) 2016-05-24 2020-05-12 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including identical twin vial adapters
US10688295B2 (en) 2013-08-07 2020-06-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with infusion liquid containers
US10765604B2 (en) 2016-05-24 2020-09-08 West Pharma. Services IL, Ltd. Drug vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter
US10772798B2 (en) 2016-12-06 2020-09-15 West Pharma Services Il, Ltd. Liquid transfer device with integral telescopic vial adapter for use with infusion liquid container and discrete injection vial
US10806667B2 (en) 2016-06-06 2020-10-20 West Pharma. Services IL, Ltd. Fluid transfer devices for filling drug pump cartridges with liquid drug contents
US10806671B2 (en) 2016-08-21 2020-10-20 West Pharma. Services IL, Ltd. Syringe assembly
USD903864S1 (en) 2018-06-20 2020-12-01 West Pharma. Services IL, Ltd. Medication mixing apparatus
US10945921B2 (en) 2017-03-29 2021-03-16 West Pharma. Services IL, Ltd. User actuated liquid drug transfer devices for use in ready-to-use (RTU) liquid drug transfer assemblages
USD917693S1 (en) 2018-07-06 2021-04-27 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923812S1 (en) 2019-01-16 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923782S1 (en) 2019-01-17 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
WO2021150453A1 (en) * 2020-01-21 2021-07-29 Becton, Dickinson And Company Vial adapter device
USD954253S1 (en) 2019-04-30 2022-06-07 West Pharma. Services IL, Ltd. Liquid transfer device
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device
US11642285B2 (en) 2017-09-29 2023-05-09 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including twin vented female vial adapters
US11918542B2 (en) 2019-01-31 2024-03-05 West Pharma. Services IL, Ltd. Liquid transfer device

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114960A0 (en) 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
IL161660A0 (en) 2004-04-29 2004-09-27 Medimop Medical Projects Ltd Liquid drug delivery device
ATE529088T1 (en) 2005-08-11 2011-11-15 Medimop Medical Projects Ltd TRANSFER DEVICES FOR LIQUID MEDICINAL PRODUCTS FOR FAIL-SAFE CORRECT LATCH CONNECTION ON MEDICAL AMPOULES
PL1971531T3 (en) * 2005-11-30 2010-01-29 Biocorp Rech Et Developpement Plug device for a container and container provided with one such device
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
EP2188004A4 (en) 2007-08-21 2015-06-17 Yukon Medical Llc Vial access and injection system
JP2010538744A (en) 2007-09-18 2010-12-16 メディモップ・メディカル・プロジェクツ・リミテッド Drug mixing injection device
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
ES2675849T3 (en) * 2008-03-28 2018-07-13 Orion Diagnostica Oy Sampling and dispensing method
WO2009146088A1 (en) 2008-04-01 2009-12-03 Yukon Medical, Llc Dual container fluid transfer device
US8512309B2 (en) * 2009-01-15 2013-08-20 Teva Medical Ltd. Vial adapter element
USD641080S1 (en) * 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
USD655017S1 (en) 2010-06-17 2012-02-28 Yukon Medical, Llc Shroud
MX345215B (en) * 2010-08-06 2017-01-19 Hospira Australia Pty Ltd Vial preparation method and system.
USD669980S1 (en) 2010-10-15 2012-10-30 Medimop Medical Projects Ltd. Vented vial adapter
FR2967655B1 (en) * 2010-11-24 2014-03-14 Biocorp Rech Et Dev DEVICE FOR CLOSING A CONTAINER, CONTAINER EQUIPPED WITH SUCH A DEVICE AND METHOD FOR CLOSING A BATCH OF SUCH CONTAINERS
USD681230S1 (en) 2011-09-08 2013-04-30 Yukon Medical, Llc Shroud
US20130173295A1 (en) 2011-12-30 2013-07-04 Elwha LLC, a limited liability company of the State of Delaware Evidence-based healthcare information management protocols
US10559380B2 (en) 2011-12-30 2020-02-11 Elwha Llc Evidence-based healthcare information management protocols
US10528913B2 (en) 2011-12-30 2020-01-07 Elwha Llc Evidence-based healthcare information management protocols
US10679309B2 (en) 2011-12-30 2020-06-09 Elwha Llc Evidence-based healthcare information management protocols
US10475142B2 (en) 2011-12-30 2019-11-12 Elwha Llc Evidence-based healthcare information management protocols
US10552581B2 (en) 2011-12-30 2020-02-04 Elwha Llc Evidence-based healthcare information management protocols
US10340034B2 (en) 2011-12-30 2019-07-02 Elwha Llc Evidence-based healthcare information management protocols
USD769444S1 (en) 2012-06-28 2016-10-18 Yukon Medical, Llc Adapter device
US20150217058A1 (en) 2012-09-24 2015-08-06 Enable Injections, Llc Medical vial and injector assemblies and methods of use
CN105246529B (en) 2013-05-03 2019-06-14 科尼尔赛德生物医学公司 Device and method for ocular injection
ITTO20130432A1 (en) * 2013-05-29 2014-11-30 Borla Ind ACCESSORY FOR VIALS
DK3682920T3 (en) 2013-06-18 2022-10-03 Enable Injections Inc APPARATUS AND PROCEDURE FOR VIAL TRANSFER AND INJECTION
WO2016159578A1 (en) * 2015-03-27 2016-10-06 바디텍메드(주) Sample collection and division device for examining biological sample
US10039913B2 (en) * 2015-07-30 2018-08-07 Carefusion 303, Inc. Tamper-resistant cap
CN106166113B (en) * 2016-08-03 2018-12-14 山东新华安得医疗用品有限公司 A kind of closed fluid handling device and a kind of closed fluid transfer method
ES2809374T3 (en) * 2016-08-22 2021-03-04 Lilly Co Eli Insured drug transfer system
US11083851B2 (en) 2016-09-17 2021-08-10 Ethan Pedde Methods, systems and devices for administering medication
EP3320929A1 (en) * 2016-11-10 2018-05-16 Sensile Pat AG Drug delivery device
USD907193S1 (en) 2018-02-21 2021-01-05 Eli Lilly And Company Secured medication transfer set
CN109044826A (en) * 2018-07-25 2018-12-21 重庆莱美药业股份有限公司 A kind of mixed medicine glass with clamp structure
US11674614B2 (en) 2020-10-09 2023-06-13 Icu Medical, Inc. Fluid transfer device and method of use for same
USD1010112S1 (en) 2021-07-03 2024-01-02 KAIRISH INNOTECH Private Ltd. Vial adapter with valve

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001091693A2 (en) * 2000-06-02 2001-12-06 Carmel Pharma Ab Coupling device for coupling a vial connector to a drug vial
US20030199847A1 (en) * 2002-04-17 2003-10-23 Roger Akerlund Method and device for fluid transfer in an infusion system

Family Cites Families (307)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US62333A (en) 1867-02-26 Henry holl
US1704817A (en) 1928-01-17 1929-03-12 Okadee Company Locomotive-cylinder cock
US1930944A (en) 1932-12-21 1933-10-17 Jr William L Schmitz Measuring dispenser
US2326490A (en) 1942-06-13 1943-08-10 Harold N Perelson Fluid dispenser
US3059643A (en) 1954-12-10 1962-10-23 Baxter Laboratories Inc Pumping apparatus
US2931668A (en) 1956-04-30 1960-04-05 Bastian Blessing Co Coupling
US2968497A (en) 1958-02-05 1961-01-17 Avro Aircraft Ltd Self-sealing coupling
DE1945279U (en) 1966-07-02 1966-09-01 Gruenenthal Chemie AUXILIARY DEVICE FOR THE PRODUCTION OF STERILE SOLUTIONS.
FR2029242A5 (en) 1969-01-21 1970-10-16 Alriq Christian Self-perforable plug for bacteriological - culture tubes
DE1913926A1 (en) 1969-03-19 1970-09-24 Hoechst Ag Two-chamber syringe
US3757981A (en) 1969-11-24 1973-09-11 Harris R Valves and valve needle syringes
US3618637A (en) 1970-02-04 1971-11-09 Deseret Pharma Rotary mixing valve
US3826261A (en) 1971-12-27 1974-07-30 Upjohn Co Vial and syringe assembly
US4109670A (en) 1973-05-16 1978-08-29 Slagel Roger D Combination check flow control and selector valve
US3855607A (en) * 1973-05-29 1974-12-17 Rca Corp Semiconductor injection laser with reduced divergence of emitted beam
US3885607A (en) 1973-11-16 1975-05-27 Richard I Peltier Device for providing fluid communication between two sealed vessels
FR2268707B1 (en) 1974-04-26 1976-12-17 Becton Dickinson France
US3977555A (en) 1974-05-07 1976-08-31 Pharmaco, Inc. Protective safety cap for medicament vial
US3957052A (en) 1974-09-13 1976-05-18 Medical Development Corporation Pumping-syringe
US3993063A (en) 1975-06-16 1976-11-23 Union Carbide Corporation Protective shielding assembly for use in loading a hypodermic syringe with radioactive material
US4051852A (en) 1975-06-26 1977-10-04 The Kendall Company Aspirating device
US4020839A (en) 1976-02-26 1977-05-03 Parke, Davis & Company Medicament-dispensing package
US4210173A (en) 1976-12-06 1980-07-01 American Hospital Supply Corporation Syringe pumping system with valves
US4187848A (en) 1977-07-18 1980-02-12 The Kendall Company Adapter assembly
USD257286S (en) 1978-03-06 1980-10-07 Tronomed International, Inc. Medical valve
US4314586A (en) 1978-08-30 1982-02-09 Tronomed International, Inc. Disposable valve
US4639019A (en) 1979-06-04 1987-01-27 Baxter Travenol Laboratories, Inc. Luer connection
US4296786A (en) 1979-09-28 1981-10-27 The West Company Transfer device for use in mixing a primary solution and a secondary or additive substance
US4253501A (en) 1979-11-09 1981-03-03 Ims Limited Transfer system
USD267199S (en) 1980-07-17 1982-12-07 Abbott Laboratories Vial and solution container connecting device
USD271421S (en) 1981-06-12 1983-11-15 Fetterman James W Medical valve
US4493348A (en) 1981-06-29 1985-01-15 Pur/Acc Corporation Method and apparatus for orally dispensing liquid medication
US4434823A (en) 1981-06-29 1984-03-06 American Hospital Supply Corporation Liquid transfer device
US4475915A (en) 1982-05-07 1984-10-09 Sloane Glenn L Holder for a syringe and an ampoule
US4588396A (en) 1982-10-22 1986-05-13 Stroebel Maurice G Apparatus for gravity feed of liquid under constant hydrostatic pressure
USD280018S (en) 1982-10-25 1985-08-06 Commonwealth Industries Syringe loading guide
AU575814B2 (en) 1983-03-03 1988-08-11 Bengt Gustavsson A device for transferring a substance
US4676530A (en) 1983-04-07 1987-06-30 Warner-Lambert Company Coupling assembly for use in fluid flow systems
US4778447A (en) 1983-05-20 1988-10-18 Travenol European Research & Development Center Connectors
JPS6026391U (en) 1983-07-30 1985-02-22 株式会社ハーマン pipe fittings
US4532969A (en) 1983-09-21 1985-08-06 Kwaan Hau C Fluid withdrawal and instillation device
USD284603S (en) 1983-11-25 1986-07-08 Loignon Edward G Syphon fitting
US4743243A (en) 1984-01-03 1988-05-10 Vaillancourt Vincent L Needle with vent filter assembly
IT1173370B (en) 1984-02-24 1987-06-24 Erba Farmitalia SAFETY DEVICE TO CONNECT A SYRINGE TO THE MOUTH OF A BOTTLE CONTAINING A DRUG OR A TUBE FOR DISPENSING THE SYRINGE DRUG
US5088996A (en) 1984-04-16 1992-02-18 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4697622A (en) 1984-06-01 1987-10-06 Parker Hannifin Corporation Passive filling device
US4588403A (en) 1984-06-01 1986-05-13 American Hospital Supply Corporation Vented syringe adapter assembly
US4604093A (en) 1984-06-12 1986-08-05 I-Flow Corporation Apparatus and method for administering multiple fluid infusions
US5113904A (en) 1984-07-13 1992-05-19 Aslanian Jerry L Flow control device for administration of intravenous fluids
US4607671A (en) 1984-08-21 1986-08-26 Baxter Travenol Laboratories, Inc. Reconstitution device
US4759756A (en) 1984-09-14 1988-07-26 Baxter Travenol Laboratories, Inc. Reconstitution device
US4614437A (en) 1984-11-02 1986-09-30 Dougherty Brothers Company Mixing container and adapter
US4721133A (en) 1985-09-26 1988-01-26 Alcon Laboratories, Inc. Multiple use valving device
US4667927A (en) 1985-11-08 1987-05-26 Rao Medical Devices, Inc. Liquid flow metering device
US4865592A (en) 1986-02-20 1989-09-12 Becton, Dickinson And Company Container and needle assembly
US4834152A (en) 1986-02-27 1989-05-30 Intelligent Medicine, Inc. Storage receptacle sealing and transfer apparatus
US5049129A (en) 1986-05-29 1991-09-17 Zdeb Brian D Adapter for passive drug delivery system
SE461765B (en) 1986-07-10 1990-03-26 Haessle Ab DEVICE FOR RELEASE OF SUBSTANCE
IT1201801B (en) 1986-08-04 1989-02-02 Pietro Cosmai MIXER LOADER FOR TRANSCUTANEOUS INJECTORS
US4743229A (en) 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4729401A (en) 1987-01-29 1988-03-08 Burron Medical Inc. Aspiration assembly having dual co-axial check valves
US5041105A (en) 1987-03-03 1991-08-20 Sherwood Medical Company Vented spike connection component
US4787898A (en) 1987-05-12 1988-11-29 Burron Medical Inc. Vented needle with sideport
US4758235A (en) 1987-05-26 1988-07-19 Tu Ho C Cardiopulmonary resuscitation medication assembly
US5178607A (en) 1987-07-31 1993-01-12 Lynn Lawrence A Blood aspiration assembly septum and blunt needle aspirator
IT211830Z2 (en) 1987-09-22 1989-05-25 Farmitalia Carl Erba S P A SAFETY DEVICE FOR THE INTRODUCTION AND WITHDRAWAL OF LIQUIDS IN AND FROM DRUG BOTTLES AND SIMILAR.
USD314050S (en) 1987-11-27 1991-01-22 Terumo Kabushiki Kaisha Medical connector
US5211638A (en) 1988-01-25 1993-05-18 Baxter International Inc. Pre-slit injection site
DE3804429A1 (en) 1988-02-12 1989-08-24 Schleicher & Schuell Gmbh DISPOSABLE FILTER
US6344031B1 (en) 1989-03-22 2002-02-05 Laurel A. Novacek Safety syringe needle device with interchangeable and retractable needle platform
US5122124A (en) 1988-12-14 1992-06-16 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5035686A (en) 1989-01-27 1991-07-30 C. R. Bard, Inc. Catheter exchange system with detachable luer fitting
US5135492A (en) 1989-06-26 1992-08-04 University Of Florida Arterial/venous fluid transfer system
US4967797A (en) 1989-08-16 1990-11-06 Manska Wayne E Tap valve
US5053015A (en) 1989-08-30 1991-10-01 The Kendall Company Locking catheter adapter
US4997430A (en) 1989-09-06 1991-03-05 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Method of and apparatus for administering medicament to a patient
US5578015A (en) 1989-09-18 1996-11-26 Robb Pascal Patent Limited Safety syringe incorporating automatic needle holder release
US5052068A (en) * 1989-11-14 1991-10-01 Graebe Robert H Contoured seat cushion
US5061248A (en) 1990-04-04 1991-10-29 Sacco John J Injection port safety shield
USRE38996E1 (en) 1990-04-20 2006-02-28 Becton, Dickinson And Company Needle tip cover
US5104387A (en) 1990-05-25 1992-04-14 St. Jude Medical, Inc. Bi-planar fluid control valve
US5045066A (en) 1990-06-07 1991-09-03 Smith & Nephew, Inc. Dental needle with stick resistant protective sleeve
US5203775A (en) 1990-09-18 1993-04-20 Medex, Inc. Needleless connector sample site
US5125908A (en) 1990-10-19 1992-06-30 Cohen Milton J Hypodermic syringe with protective holder
US5201717A (en) 1990-12-05 1993-04-13 Philip Wyatt Safety enclosure
JP3066611B2 (en) 1991-04-30 2000-07-17 武田薬品工業株式会社 Aseptic holding and mixing device for two drugs housed in individually sealed containers
US5183469A (en) 1991-05-10 1993-02-02 Becton, Dickinson And Company Device for the removal and replacement of a needle shield
DE4122221A1 (en) 1991-07-04 1993-03-18 Axel Von Brand TRANSFER AND REMOVAL SPIKE
DE4122476A1 (en) 1991-07-06 1993-01-07 Leopold Pharma Gmbh Sterile liq. transfer in e.g. medical infusion mixts. - using double, self sealing, spined cannula coupling
US5288290A (en) 1991-09-25 1994-02-22 Alcon Surgical, Inc. Multi-ported valve assembly
WO1993010001A1 (en) 1991-11-21 1993-05-27 Gds Technology, Inc. Fluid transfer device
US5171230A (en) 1991-11-29 1992-12-15 Medex, Inc. Fast flush catheter valve
US5247972A (en) 1991-12-17 1993-09-28 Whittier Medical, Inc. Alignment guide for hypodermic syringe
US5279597A (en) 1992-01-13 1994-01-18 Arrow International Investment Corp. Catheter compression clamp
CA2093560C (en) 1992-04-10 2005-06-07 Minoru Honda Fluid container
US5328474A (en) 1992-04-13 1994-07-12 B. Braun Medical Inc. Tamper resistant syringe cap
JP2605345Y2 (en) 1992-05-01 2000-07-10 株式会社大塚製薬工場 Drug container
JPH05317383A (en) 1992-05-19 1993-12-03 Nissho Corp Solution container equipped with means for communicating with chemical container
US5279576A (en) 1992-05-26 1994-01-18 George Loo Medication vial adapter
US5232109A (en) 1992-06-02 1993-08-03 Sterling Winthrop Inc. Double-seal stopper for parenteral bottle
GB9211912D0 (en) 1992-06-04 1992-07-15 Drg Flexpak Ltd Vial connector system
CZ29095A3 (en) 1992-08-07 1995-07-12 West Co Closing device for little containers, particularly for medicaments, for providing access without need of needle
US5344417A (en) 1992-09-11 1994-09-06 Becton, Dickinson And Company Universal fitting for inoculation receptacles
US5334163A (en) 1992-09-16 1994-08-02 Sinnett Kevin B Apparatus for preparing and administering a dose of a fluid mixture for injection into body tissue
US5385547A (en) 1992-11-19 1995-01-31 Baxter International Inc. Adaptor for drug delivery
DK0625917T3 (en) 1992-12-15 1998-09-28 Sanofi Sa Device for preparing a solution, suspension or emulsion of a medical substance
US5269768A (en) 1993-02-08 1993-12-14 Smiths Industries Medical Systems, Inc. Valved suction catheter
US5312377A (en) 1993-03-29 1994-05-17 Dalton Michael J Tapered luer connector
US5591143A (en) 1993-04-02 1997-01-07 Medrad Inc. Luer connector with torque indicator
US5607439A (en) 1993-06-24 1997-03-04 Yoon; Inbae Safety penetrating instrument with penetrating member moving during penetration and triggered safety member protrusion
US5445630A (en) 1993-07-28 1995-08-29 Richmond; Frank M. Spike with luer fitting
US5364387A (en) 1993-08-02 1994-11-15 Becton, Dickinson And Company Drug access assembly for vials and ampules
US5397303A (en) 1993-08-06 1995-03-14 River Medical, Inc. Liquid delivery device having a vial attachment or adapter incorporated therein
CA2170160C (en) 1993-09-07 2002-08-27 Frederic Neftel Syringe device for mixing two compounds
SE9303178D0 (en) 1993-09-29 1993-09-29 Kabi Pharmacia Ab Improvements in injection cartridges
US5509433A (en) 1993-10-13 1996-04-23 Paradis; Joseph R. Control of fluid flow
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5520659A (en) 1994-03-09 1996-05-28 Joseph K. Andonian Syringe needle cover and vial connector
US5462317A (en) 1994-03-23 1995-10-31 Keller; Wilhelm A. Adapter for a mixing or dispensing device
DE4414697C2 (en) 1994-04-27 1998-06-18 Caremed Vertriebsgesellschaft Device for transferring and removing liquids from bottles, bags or similar containers for medical purposes
US5832971A (en) 1994-05-19 1998-11-10 Becton, Dickinson And Company Syringe filling and delivery device
US5746733A (en) 1994-05-19 1998-05-05 Becton, Dickinson And Company Syringe filling and delivery device
US5583052A (en) 1994-05-23 1996-12-10 The Liposome Company, Inc. Formulation preparation device
US5649637A (en) 1994-06-02 1997-07-22 Automatic Liquid Packaging, Inc. Torque-resistant closure for a hermetically sealed container
US5470319A (en) 1994-06-20 1995-11-28 Critical Device Corporation Needleless injection site
WO1996000053A1 (en) 1994-06-24 1996-01-04 Icu Medical, Inc. Fluid transfer device and method of use
EP0692235A1 (en) 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5526853A (en) 1994-08-17 1996-06-18 Mcgaw, Inc. Pressure-activated medication transfer system
FR2726768A1 (en) 1994-11-14 1996-05-15 Debiotech Sa SYRINGE DEVICE ATTACHABLE TO A VIAL
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
GB9425642D0 (en) 1994-12-20 1995-02-22 Weston Medical Ltd Filling device
US5531695A (en) 1994-12-22 1996-07-02 Sherwood Medical Company Tamper evident sleeve
US5653686A (en) 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
US5492147A (en) 1995-01-17 1996-02-20 Aeroquip Corporation Dry break coupling
US5647845A (en) 1995-02-01 1997-07-15 Habley Medical Technology Corporation Generic intravenous infusion system
US5674195A (en) 1995-02-06 1997-10-07 Truthan; Charles Edwin Syringe apparatus and method of mixing liquid medicants within a syringe
DE19504413A1 (en) 1995-02-10 1996-08-22 Pharmacia Gmbh Transfer device
US5584819A (en) 1995-03-13 1996-12-17 Kopfer; Rudolph J. Nested blunt/sharp injection assembly
IL114960A0 (en) 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
US5651776A (en) 1995-03-22 1997-07-29 Angiodynamics, Inc. Luer-type connector
US5566729A (en) 1995-04-06 1996-10-22 Abbott Laboratories Drug reconstitution and administration system
DE19513666C1 (en) 1995-04-11 1996-11-28 Behringwerke Ag Device for bringing together a first liquid and a second solid or liquid component by means of negative pressure under sterile conditions
SE509950C2 (en) 1995-05-02 1999-03-29 Carmel Pharma Ab Device for the administration of toxic liquid
US5839715A (en) 1995-05-16 1998-11-24 Alaris Medical Systems, Inc. Medical adapter having needleless valve and sharpened cannula
US5616203A (en) 1995-07-14 1997-04-01 Merit Medical Method of manufacturing a split ring airless rotatable connector
FR2738550B1 (en) 1995-09-11 1997-11-07 Biodome DEVICE FOR SEALING A CONTAINER ITSELF CLOSED, ASSEMBLY FOR PROVIDING A PRODUCT COMPRISING SUCH A CONTAINER AND SUCH A SEALING DEVICE
US5611576A (en) 1995-11-24 1997-03-18 Industrie Borla Spa Female coupling element for haemodialysis medical equipment
US5833213A (en) 1995-12-29 1998-11-10 Rymed Technologies, Inc. Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US5879337A (en) 1997-02-27 1999-03-09 Injectimed, Inc. Needle tip guard for hypodermic needles
USD393722S (en) 1996-04-04 1998-04-21 Icu Medical, Inc. Locking blunt cannula
CA2252404A1 (en) 1996-04-22 1997-10-30 Abbott Laboratories Container closure system
DE19619026A1 (en) 1996-05-10 1997-11-13 Trinova Gmbh Quick coupling
US5873872A (en) 1996-09-17 1999-02-23 Becton Dickinson And Company Multipositional resealable vial connector assembly for efficient transfer of liquid
US5738144A (en) 1996-10-11 1998-04-14 Aeroquip Corporation Luer connecting coupling
JPH10132605A (en) * 1996-10-28 1998-05-22 Sony Precision Technol Inc Position detector
US5895383A (en) 1996-11-08 1999-04-20 Bracco Diagnostics Inc. Medicament container closure with recessed integral spike access means
US6004278A (en) 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
FR2756811B1 (en) 1996-12-06 1999-02-05 Valois DEVICE FOR DISPENSING BICOMPONENT TYPE FLUID PRODUCT
GB9701413D0 (en) 1997-01-24 1997-03-12 Smithkline Beecham Biolog Novel device
US5954104A (en) 1997-02-28 1999-09-21 Abbott Laboratories Container cap assembly having an enclosed penetrator
US5772652A (en) 1997-05-14 1998-06-30 Comar, Inc. Stab cap for a vial having a puncturable seal
US5755696A (en) 1997-06-30 1998-05-26 Becton, Dickinson And Company Syringe filling and delivery device
US5820621A (en) 1997-07-29 1998-10-13 Becton, Dickinson And Company Medical fluid transfer and delivery device
US7125397B2 (en) 1997-08-20 2006-10-24 B. Braun Melsungen Ag Protective device for an injection needle
IL121605A (en) 1997-08-22 2001-03-19 Medimop Medical Projects Ltd Fluid access assembly and a method for preparing a liquid drug
US5834744A (en) 1997-09-08 1998-11-10 The Rubbright Group Tubular microwave applicator
US5919182A (en) 1997-09-12 1999-07-06 Becton, Dickinson And Company Medical fluid transfer and delivery device
US6090093A (en) 1997-09-25 2000-07-18 Becton Dickinson And Company Connector assembly for a vial having a flexible collar
US5925029A (en) 1997-09-25 1999-07-20 Becton, Dickinson And Company Method and apparatus for fixing a connector assembly onto a vial with a crimp cap
US5944700A (en) 1997-09-26 1999-08-31 Becton, Dickinson And Company Adjustable injection length pen needle
US5902298A (en) 1997-11-07 1999-05-11 Bracco Research Usa Medicament container stopper with integral spike access means
IT236233Y1 (en) 1997-11-26 2000-08-08 Eurospital S P A DEVICE FOR THE CONNECTION OF A PHARMACEUTICAL PRODUCT CONTAINER TO A BAG OF LIQUID PRODUCT TO CARRY OUT THE
US5989237A (en) 1997-12-04 1999-11-23 Baxter International Inc. Sliding reconstitution device with seal
US6457488B2 (en) 1998-01-08 2002-10-01 George Loo Stopcock having axial port for syringe twist actuation
FR2773735B1 (en) 1998-01-20 2000-02-25 Becton Dickinson France WATERPROOF CONTAINMENT DEVICE
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6080132A (en) 1998-02-27 2000-06-27 Abbott Laboratories Apparatus for altering characteristics of a fluid
US6957745B2 (en) 1998-04-20 2005-10-25 Becton, Dickinson And Company Transfer set
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6245044B1 (en) 1998-07-17 2001-06-12 Becton, Dickinson And Company Variable extension combined spinal/epidural needle set and method for its use
US6358236B1 (en) 1998-08-06 2002-03-19 Baxter International Inc. Device for reconstituting medicaments for injection
GB2359754B (en) 2000-03-03 2004-04-28 Nmt Group Plc Needle sheath
US20050137566A1 (en) 2003-12-23 2005-06-23 Fowles Thomas A. Sliding reconstitution device for a diluent container
US7074216B2 (en) 1998-09-15 2006-07-11 Baxter International Inc. Sliding reconstitution device for a diluent container
US6022339A (en) 1998-09-15 2000-02-08 Baxter International Inc. Sliding reconstitution device for a diluent container
AR021220A1 (en) 1998-09-15 2002-07-03 Baxter Int CONNECTION DEVICE FOR ESTABLISHING A FLUID COMMUNICATION BETWEEN A FIRST CONTAINER AND A SECOND CONTAINER.
USD427308S (en) 1999-01-22 2000-06-27 Medimop Medical Projects Ltd. Vial adapter
FR2789369B1 (en) 1999-02-10 2001-04-27 Biodome CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE
US6099511A (en) 1999-03-19 2000-08-08 Merit Medical Systems, Inc. Manifold with check valve positioned within manifold body
US6231552B1 (en) 1999-05-04 2001-05-15 Saf-T-Med, Inc. Threaded latching mechanism
US6156025A (en) 1999-06-17 2000-12-05 Bracco Research Usa Inc. Twist valve
US6348044B1 (en) 1999-10-12 2002-02-19 George D. N. Coletti Method and apparatus for recapping single-use hypodermic needles
EP1237598B1 (en) 1999-10-22 2017-11-22 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US7198618B2 (en) 1999-11-04 2007-04-03 Tyco Healthcare Group Lp Safety shield for medical needles
FR2800713B1 (en) 1999-11-05 2002-01-04 Biodome CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE
US6832994B2 (en) 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US6503240B1 (en) 2000-01-24 2003-01-07 Brocco Diagnostics, Inc. Vial access adapter
US6139534A (en) 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
US6544246B1 (en) 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
USD445501S1 (en) 2000-01-24 2001-07-24 Bracco Diagnostics, Inc. Vial access adapter
DE50007821D1 (en) 2000-02-16 2004-10-21 Haselmeier S A R L METHOD FOR THE RECONSTITUTION OF AN INJECTION LIQUID, AND INJECTION DEVICE FOR IMPLEMENTING SUCH A METHOD
US6530903B2 (en) 2000-02-24 2003-03-11 Xiping Wang Safety syringe
JP4372310B2 (en) 2000-04-10 2009-11-25 ニプロ株式会社 Adapter for mixed injection
WO2002009797A1 (en) 2000-08-02 2002-02-07 Becton Dickinson And Company Pen needle and safety shield system
JP2004508897A (en) 2000-09-21 2004-03-25 エラン・ファルマ・インターナショナル・リミテッド Reshaping and injection system
JP2002177392A (en) 2000-11-08 2002-06-25 West Pharmaceutical Services Inc Safety device of syringe
US6666852B2 (en) 2000-12-04 2003-12-23 Bracco Diagnostics, Inc. Axially activated vial access adapter
US20020087118A1 (en) 2000-12-29 2002-07-04 Duoject Medical Systems Inc. Pharmaceutical delivery system
US6558365B2 (en) 2001-01-03 2003-05-06 Medimop Medical Projects, Ltd. Fluid transfer device
USD468015S1 (en) 2001-01-22 2002-12-31 Astra Tech Ab Combined connector with valve and non-return valve for medical equipment
US6474375B2 (en) 2001-02-02 2002-11-05 Baxter International Inc. Reconstitution device and method of use
US6656433B2 (en) 2001-03-07 2003-12-02 Churchill Medical Systems, Inc. Vial access device for use with various size drug vials
US6503244B2 (en) 2001-03-07 2003-01-07 Micro Therapeutics, Inc. High pressure injection system
US6581593B1 (en) 2001-04-03 2003-06-24 Darren A. Rubin Universal oxygen connector system
US6745998B2 (en) 2001-08-10 2004-06-08 Alaris Medical Systems, Inc. Valved male luer
FR2829691B1 (en) 2001-09-17 2004-07-09 Sedat DEVICE FOR BIDIRECTIONAL TRANSFER OF A LIQUID BETWEEN A BOTTLE AND A CARPULE
US7354422B2 (en) 2001-09-26 2008-04-08 B. Braun Melsungen Ag Spring launched needle safety clip
JP4817564B2 (en) 2001-09-28 2011-11-16 株式会社細川洋行 Needle case and infusion container
US6715520B2 (en) 2001-10-11 2004-04-06 Carmel Pharma Ab Method and assembly for fluid transfer
JP3945480B2 (en) 2001-11-14 2007-07-18 株式会社ジェイ・エム・エス Three-way stopcock and infusion circuit or transfusion circuit using the three-way stopcock
US6802828B2 (en) 2001-11-23 2004-10-12 Duoject Medical Systems, Inc. System for filling and assembling pharmaceutical delivery devices
PT1448256E (en) 2001-11-30 2006-06-30 Novo Nordisk As ASSEMBLY OF A SAFETY NEEDLE
ES2605734T3 (en) 2001-12-13 2017-03-16 Becton, Dickinson And Company Needle closure system extractor
US6875205B2 (en) 2002-02-08 2005-04-05 Alaris Medical Systems, Inc. Vial adapter having a needle-free valve for use with vial closures of different sizes
USD472630S1 (en) 2002-04-30 2003-04-01 Sterling Medivations, Inc. Pen needle catheter connector
USD472316S1 (en) 2002-04-30 2003-03-25 Sterling Medivations, Inc. Pen needle catheter connector
USD476733S1 (en) 2002-05-09 2003-07-01 Becton, Dickinson And Company Medical needle assembly
WO2003097137A2 (en) 2002-05-16 2003-11-27 Scott Laboratories, Inc. Drug container entry mechanisms and method
JP4427965B2 (en) 2002-07-02 2010-03-10 ニプロ株式会社 Chemical container with communication means
JP4209642B2 (en) 2002-07-26 2009-01-14 川澄化学工業株式会社 Needle cover and needle cover with cap and needle with wing with needle cover
US7083600B2 (en) 2002-08-08 2006-08-01 Advanced Medical Sharps, Inc. Safety needle and shield
JP2004097253A (en) 2002-09-04 2004-04-02 Nipro Corp Liquid transfusion device
US20040073189A1 (en) 2002-10-09 2004-04-15 Phil Wyatt Vial access transfer set
USD483869S1 (en) 2002-10-29 2003-12-16 Pre Holding, Inc. Tubing connector
CA2505104A1 (en) 2002-11-08 2004-05-21 Duoject Medical Systems Inc. Pharmaceutical delivery systems and methods for using same
US8100879B2 (en) 2002-11-18 2012-01-24 Nestec S.A. Connector device for enteral administration set
JP4341239B2 (en) 2002-12-19 2009-10-07 ニプロ株式会社 Liquid transfer tool
USD483487S1 (en) 2002-12-19 2003-12-09 Becton Dickinson And Company Stopcock device
EP1454609B1 (en) 2003-03-05 2012-10-24 CSL Behring GmbH Transfer device
EP1454650B1 (en) 2003-03-06 2007-10-10 CSL Behring GmbH Transfer device, in particular for medical fluids
US20040181192A1 (en) 2003-03-11 2004-09-16 Cuppy Michael John Vascular access device and method of using same
US7470265B2 (en) 2003-03-20 2008-12-30 Nxstage Medical, Inc. Dual access spike for infusate bags
US7024968B2 (en) 2003-03-26 2006-04-11 Boston Scientific Scimed, Inc. Luer lock wrench
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
US7040598B2 (en) 2003-05-14 2006-05-09 Cardinal Health 303, Inc. Self-sealing male connector
USD495416S1 (en) 2003-05-30 2004-08-31 Alaris Medical Systems, Inc. Vial access device
JP3883527B2 (en) 2003-07-17 2007-02-21 ニプロ株式会社 Transfer needle
US7488297B2 (en) 2003-07-30 2009-02-10 Patrice Flaherty Blood collecting devices
FR2858931B1 (en) 2003-08-21 2007-04-13 Becton Dickinson France DEVICE FOR ORAL ADMINISTRATION OF A MEDICINAL PRODUCT
US7722090B2 (en) 2004-03-26 2010-05-25 Cook Incorporated Method and apparatus for an improved luer fitting connection
IL161660A0 (en) 2004-04-29 2004-09-27 Medimop Medical Projects Ltd Liquid drug delivery device
FR2869795B1 (en) 2004-05-07 2006-08-04 Sedat Sa BIDIRECTIONAL TRANSFER DEVICE
DE202004012714U1 (en) 2004-08-12 2004-11-04 Smiths Medical Deutschland Gmbh Luer lock connector for medical devices
US7984730B2 (en) 2004-09-03 2011-07-26 Elcam Medical Agricultural Cooperative Association Stopcock
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7771383B2 (en) 2004-10-22 2010-08-10 Medegen, Inc. Fluid control device with valve and methods of use
US7192423B2 (en) 2004-11-17 2007-03-20 Cindy Wong Dispensing spike assembly with removable indicia bands
US7523967B2 (en) 2004-12-13 2009-04-28 Alcon, Inc. Tubing fitting
US20060135948A1 (en) 2004-12-16 2006-06-22 Medtronic Vascular, Inc., A Delaware Corporation Multi-exchange catheter guide member with improved seal
ES2354018T3 (en) 2005-02-14 2011-03-09 Medimop Medical Projects Ltd. MEDICAL DEVICE FOR THE IN SITU RECONSTITUTION OF LIQUID DRUGS IN MEDICINAL CONTAINERS.
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
US20060253084A1 (en) 2005-05-03 2006-11-09 Greg Nordgren Outdwelling slit valves and assemblies for medical liquid flow through a cannula and related methods
US20070088293A1 (en) 2005-07-06 2007-04-19 Fangrow Thomas F Jr Medical connector with closeable male luer
EP1909735A1 (en) 2005-08-01 2008-04-16 Medimop Medical Projects Ltd. Liquid drug delivery system
ATE529088T1 (en) 2005-08-11 2011-11-15 Medimop Medical Projects Ltd TRANSFER DEVICES FOR LIQUID MEDICINAL PRODUCTS FOR FAIL-SAFE CORRECT LATCH CONNECTION ON MEDICAL AMPOULES
US7882863B2 (en) 2005-10-19 2011-02-08 Cd Solutions, Llc Apparatus and method for mixing and transferring medications
US7611502B2 (en) 2005-10-20 2009-11-03 Covidien Ag Connector for enteral fluid delivery set
PL1951344T3 (en) 2005-11-07 2015-02-27 Borla Ind Vented safe handling vial adapter
JP2007143813A (en) 2005-11-28 2007-06-14 Nippon Sherwood Medical Industries Ltd Medical stopcock
US20070191767A1 (en) 2005-12-16 2007-08-16 Medtronic Vascular, Inc. Bifurcated Catheter Joints
US7981101B2 (en) 2005-12-30 2011-07-19 Carefusion 303, Inc. Medical vial adapter with reduced diameter cannula and enlarged vent lumen
EP1820485B1 (en) 2006-02-16 2009-11-11 F.Hoffmann-La Roche Ag System and apparatus for extracting drugs
IL174352A0 (en) 2006-03-16 2006-08-20 Medimop Medical Projects Ltd Medical devices for use with carpules
JP4769103B2 (en) 2006-03-17 2011-09-07 日本シャーウッド株式会社 connector
JP4775638B2 (en) 2006-03-31 2011-09-21 株式会社ジェイ・エム・エス Communication member, medical container using the same, and infusion dispensing device set
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
JP4820703B2 (en) 2006-04-28 2011-11-24 日本シャーウッド株式会社 Liquid infusion tool
JP4871019B2 (en) 2006-05-15 2012-02-08 日本コヴィディエン株式会社 Liquid infusion tool
AU2007262025B2 (en) 2006-06-19 2013-03-14 Nipro Corporation Drug Solution Preparation Kit
JP2008005974A (en) 2006-06-28 2008-01-17 Nippon Sherwood Medical Industries Ltd Lure fixing, fitting and connecting structure
ATE465710T1 (en) 2006-07-21 2010-05-15 Polimoon Medical Packaging As CONNECTION DEVICE AND STERILE MIXING METHOD
USD561348S1 (en) 2006-08-17 2008-02-05 Medimop Medical Projects Ltd. Vial adapter
US8167863B2 (en) 2006-10-16 2012-05-01 Carefusion 303, Inc. Vented vial adapter with filter for aerosol retention
WO2008067511A1 (en) 2006-11-30 2008-06-05 Medi-Physics, Inc. Dual-lumen needle with an elongate notch opening
US20100030181A1 (en) 2006-11-30 2010-02-04 Kevin Helle Dual-lumen needle
US7758082B2 (en) 2006-12-05 2010-07-20 Nxstage Medical, Inc. Fluid line connector safety device
US7883499B2 (en) 2007-03-09 2011-02-08 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
IL182922A0 (en) 2007-05-02 2007-09-20 Medimop Medical Projects Ltd Automatic liquid drug reconstitution apparatus
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
JP5615176B2 (en) 2007-08-30 2014-10-29 カルメル ファルマ アクチボラゲット Fluid transfer device
JP2010538744A (en) 2007-09-18 2010-12-16 メディモップ・メディカル・プロジェクツ・リミテッド Drug mixing injection device
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
DE102007061346A1 (en) 2007-12-17 2009-06-18 Bayer Schering Pharma Aktiengesellschaft Spike with two thorns
CA2711588C (en) 2008-01-09 2017-03-14 Novartis Ag Unitary withdrawal spike unit suitable for factory fitting
US8287496B2 (en) 2008-01-17 2012-10-16 Custom Medical Applications, Inc. Flow elements for use with flexible spinal needles, needle assemblies and methods therefor
IL188975A0 (en) 2008-01-23 2008-11-03 Medimop Medical Projects Ltd Fluid control device with stopper
DE102008002800A1 (en) 2008-03-10 2009-09-24 Süddeutsche Feinmechanik GmbH mixing device
US7967785B2 (en) 2008-07-14 2011-06-28 Nipro Healthcare Systems, Llc Insulin reservoir detection via magnetic switching
USD595863S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595421S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595862S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595420S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001091693A2 (en) * 2000-06-02 2001-12-06 Carmel Pharma Ab Coupling device for coupling a vial connector to a drug vial
US20030199847A1 (en) * 2002-04-17 2003-10-23 Roger Akerlund Method and device for fluid transfer in an infusion system

Cited By (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8435210B2 (en) 2007-04-17 2013-05-07 Medimop Medical Projects Ltd. Fluid control device with manually depressed actuator
US8998875B2 (en) 2009-10-01 2015-04-07 Medimop Medical Projects Ltd. Vial assemblage with vial and pre-attached fluid transfer device
US8608723B2 (en) 2009-11-12 2013-12-17 Medimop Medical Projects Ltd. Fluid transfer devices with sealing arrangement
US9132063B2 (en) 2009-11-12 2015-09-15 Medimop Medical Projects Ltd. Inline liquid drug medical devices with linear displaceable sliding flow control member
US8979792B2 (en) 2009-11-12 2015-03-17 Medimop Medical Projects Ltd. Inline liquid drug medical devices with linear displaceable sliding flow control member
US8753325B2 (en) 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
US8684994B2 (en) 2010-02-24 2014-04-01 Medimop Medical Projects Ltd. Fluid transfer assembly with venting arrangement
US8852145B2 (en) 2010-11-14 2014-10-07 Medimop Medical Projects, Ltd. Inline liquid drug medical device having rotary flow control member
US8752598B2 (en) 2011-04-17 2014-06-17 Medimop Medical Projects Ltd. Liquid drug transfer assembly
CN103458850A (en) * 2011-04-17 2013-12-18 麦迪麦珀医疗工程有限公司 Liquid drug transfer assembly
US8905994B1 (en) 2011-10-11 2014-12-09 Medimop Medical Projects, Ltd. Valve assembly for use with liquid container and drug vial
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
USD737436S1 (en) 2012-02-13 2015-08-25 Medimop Medical Projects Ltd. Liquid drug reconstitution assembly
US9283324B2 (en) 2012-04-05 2016-03-15 Medimop Medical Projects, Ltd Fluid transfer devices having cartridge port with cartridge ejection arrangement
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
US10299990B2 (en) 2012-08-26 2019-05-28 West Pharma. Services IL, Ltd. Liquid drug transfer devices
US9795536B2 (en) 2012-08-26 2017-10-24 Medimop Medical Projects, Ltd. Liquid drug transfer devices employing manual rotation for dual flow communication step actuations
CN104703573A (en) * 2012-09-13 2015-06-10 麦迪麦珀医疗工程有限公司 Telescopic female drug vial adapter
US9339438B2 (en) 2012-09-13 2016-05-17 Medimop Medical Projects Ltd. Telescopic female drug vial adapter
WO2014041529A1 (en) 2012-09-13 2014-03-20 Medimop Medical Projects Ltd Telescopic female drug vial adapter
USD734868S1 (en) 2012-11-27 2015-07-21 Medimop Medical Projects Ltd. Drug vial adapter with downwardly depending stopper
US9801786B2 (en) 2013-04-14 2017-10-31 Medimop Medical Projects Ltd. Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe
US9943463B2 (en) 2013-05-10 2018-04-17 West Pharma. Services IL, Ltd. Medical devices including vial adapter with inline dry drug module
USD765837S1 (en) 2013-08-07 2016-09-06 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
USD767124S1 (en) 2013-08-07 2016-09-20 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
US10688295B2 (en) 2013-08-07 2020-06-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with infusion liquid containers
WO2015021499A1 (en) * 2013-08-13 2015-02-19 Noble House Group Pty. Ltd. Universal sampling cap
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
US10285907B2 (en) 2015-01-05 2019-05-14 West Pharma. Services IL, Ltd. Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
CN113143759A (en) * 2015-07-16 2021-07-23 西部制药服务以色列有限公司 Liquid drug transfer device for secure telescopic snap-fit on injection vial
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
CN113143759B (en) * 2015-07-16 2024-01-30 西部制药服务以色列有限公司 Liquid drug transfer device for secure telescopic snap-fit on an injection vial
USD801522S1 (en) 2015-11-09 2017-10-31 Medimop Medical Projects Ltd. Fluid transfer assembly
US10278897B2 (en) 2015-11-25 2019-05-07 West Pharma. Services IL, Ltd. Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
US10646404B2 (en) 2016-05-24 2020-05-12 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including identical twin vial adapters
US10765604B2 (en) 2016-05-24 2020-09-08 West Pharma. Services IL, Ltd. Drug vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter
US10806667B2 (en) 2016-06-06 2020-10-20 West Pharma. Services IL, Ltd. Fluid transfer devices for filling drug pump cartridges with liquid drug contents
US10806671B2 (en) 2016-08-21 2020-10-20 West Pharma. Services IL, Ltd. Syringe assembly
USD832430S1 (en) 2016-11-15 2018-10-30 West Pharma. Services IL, Ltd. Dual vial adapter assemblage
US10772797B2 (en) 2016-12-06 2020-09-15 West Pharma. Services IL, Ltd. Liquid drug transfer devices for use with intact discrete injection vial release tool
US10772798B2 (en) 2016-12-06 2020-09-15 West Pharma Services Il, Ltd. Liquid transfer device with integral telescopic vial adapter for use with infusion liquid container and discrete injection vial
US11786443B2 (en) 2016-12-06 2023-10-17 West Pharma. Services IL, Ltd. Liquid transfer device with integral telescopic vial adapter for use with infusion liquid container and discrete injection vial
US10945921B2 (en) 2017-03-29 2021-03-16 West Pharma. Services IL, Ltd. User actuated liquid drug transfer devices for use in ready-to-use (RTU) liquid drug transfer assemblages
US11642285B2 (en) 2017-09-29 2023-05-09 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including twin vented female vial adapters
CN112105328A (en) * 2018-05-17 2020-12-18 贝克顿迪金森法国公司 Connector for connecting a medical injection device to a container
US20210186814A1 (en) * 2018-05-17 2021-06-24 Becton Dickinson France Connector for Connecting a Medical Injection Device to a Container
CN112105328B (en) * 2018-05-17 2024-03-01 贝克顿迪金森法国公司 Connector for connecting a medical injection device to a container
WO2019219383A1 (en) * 2018-05-17 2019-11-21 Becton Dickinson France Connector for connecting a medical injection device to a container
USD903864S1 (en) 2018-06-20 2020-12-01 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD917693S1 (en) 2018-07-06 2021-04-27 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923812S1 (en) 2019-01-16 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923782S1 (en) 2019-01-17 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
US11918542B2 (en) 2019-01-31 2024-03-05 West Pharma. Services IL, Ltd. Liquid transfer device
USD954253S1 (en) 2019-04-30 2022-06-07 West Pharma. Services IL, Ltd. Liquid transfer device
US11484470B2 (en) 2019-04-30 2022-11-01 West Pharma. Services IL, Ltd. Liquid transfer device with dual lumen IV spike
US11786442B2 (en) 2019-04-30 2023-10-17 West Pharma. Services IL, Ltd. Liquid transfer device with dual lumen IV spike
CN113208916A (en) * 2020-01-21 2021-08-06 贝克顿·迪金森公司 Medicine bottle adapter device
WO2021150453A1 (en) * 2020-01-21 2021-07-29 Becton, Dickinson And Company Vial adapter device
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device

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ATE529088T1 (en) 2011-11-15
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