WO2006134546A3 - Accurate magnetic biosensor - Google Patents
Accurate magnetic biosensor Download PDFInfo
- Publication number
- WO2006134546A3 WO2006134546A3 PCT/IB2006/051866 IB2006051866W WO2006134546A3 WO 2006134546 A3 WO2006134546 A3 WO 2006134546A3 IB 2006051866 W IB2006051866 W IB 2006051866W WO 2006134546 A3 WO2006134546 A3 WO 2006134546A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sort
- labels
- binding sites
- magnetic
- magnetic labels
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008516478A JP2008544246A (en) | 2005-06-17 | 2006-06-12 | Accurate magnetic biosensor |
EP06765725A EP1894009A2 (en) | 2005-06-17 | 2006-06-12 | Accurate magnetic biosensor |
US11/917,211 US20080206104A1 (en) | 2005-06-17 | 2006-06-12 | Accurate Magnetic Biosensor |
BRPI0612623A BRPI0612623A2 (en) | 2005-06-17 | 2006-06-12 | sensor device, system and method for determining the concentration of at least one species of target in a fluid containing at least one species of polarizable or polarized magnetic labels |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05105361 | 2005-06-17 | ||
EP05105361.9 | 2005-06-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006134546A2 WO2006134546A2 (en) | 2006-12-21 |
WO2006134546A3 true WO2006134546A3 (en) | 2007-03-08 |
Family
ID=37309075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2006/051866 WO2006134546A2 (en) | 2005-06-17 | 2006-06-12 | Accurate magnetic biosensor |
Country Status (7)
Country | Link |
---|---|
US (1) | US20080206104A1 (en) |
EP (1) | EP1894009A2 (en) |
JP (1) | JP2008544246A (en) |
CN (1) | CN101198870A (en) |
BR (1) | BRPI0612623A2 (en) |
RU (1) | RU2415432C2 (en) |
WO (1) | WO2006134546A2 (en) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101379384A (en) * | 2006-02-03 | 2009-03-04 | 皇家飞利浦电子股份有限公司 | Magnetic sensor device with reference unit |
DE102006016334B4 (en) * | 2006-04-06 | 2018-11-15 | Boehringer Ingelheim Vetmedica Gmbh | Method and device for detecting magnetizable particles |
CN101438163B (en) * | 2006-05-09 | 2013-05-29 | 皇家飞利浦电子股份有限公司 | Detection of target molecules in a sample by using a magnetic field |
CN101438142B (en) * | 2006-05-10 | 2013-10-30 | 皇家飞利浦电子股份有限公司 | Rapid magnetic biosensor |
JP2009543038A (en) * | 2006-06-28 | 2009-12-03 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Magnetic sensor device and method for detecting magnetic particles |
JP2009544033A (en) * | 2006-07-17 | 2009-12-10 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Attraction and separation of magnetic or magnetizable objects from the sensor surface |
JP5210315B2 (en) | 2006-10-12 | 2013-06-12 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Magnetic and / or electrical label auxiliary detection system and method |
US20100182002A1 (en) * | 2007-02-23 | 2010-07-22 | Koninklijke Philips Electronics N.V. | Magnetic sensor device with field generator and sensor element |
WO2008102218A1 (en) * | 2007-02-23 | 2008-08-28 | Koninklijke Philips Electronics N.V. | A sensor device for and a method of sensing magnetic particles |
DE102007015543A1 (en) * | 2007-03-30 | 2008-10-09 | Siemens Ag | Method for detection of biological reaction products on sensor surfaces, involves moving beads into desired direction, particularly from berth to detected biologically active substances, where biological reaction products have Biotins |
EP2017618A1 (en) * | 2007-07-20 | 2009-01-21 | Koninklijke Philips Electronics N.V. | Methods and systems for detecting |
EP2017619A1 (en) * | 2007-07-20 | 2009-01-21 | Koninklijke Philips Electronics N.V. | Magnetic sensor device |
JP2009042104A (en) * | 2007-08-09 | 2009-02-26 | Canon Inc | Substance fixing device, substance detector and substance fixing method |
EP2028491A1 (en) * | 2007-08-22 | 2009-02-25 | Koninklijke Philips Electronics N.V. | Method of directing magnetic or magnetisable objects to prepare bio-sensor device |
GB0716968D0 (en) * | 2007-08-31 | 2007-10-10 | Vivacta Ltd | Sensor |
JP2011505572A (en) * | 2007-12-04 | 2011-02-24 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Method for measuring molecules in fluid using labeled particles |
EP2073016A1 (en) * | 2007-12-20 | 2009-06-24 | Koninklijke Philips Electronics N.V. | Magnetic label based detection |
KR20100115744A (en) | 2008-01-17 | 2010-10-28 | 더 리전츠 오브 더 유니버시티 오브 캘리포니아 | Integrated magnetic field generation and detection platform |
JP5628784B2 (en) * | 2008-03-17 | 2014-11-19 | コーニンクレッカ フィリップス エヌ ヴェ | Cartridge for assay with magnetic particles |
US8053250B2 (en) * | 2008-06-27 | 2011-11-08 | Rex Chin-Yih Hong | Method and system for suppressing bindings on magnetic particles |
RU2520607C2 (en) | 2008-10-17 | 2014-06-27 | Конинклейке Филипс Электроникс Н.В. | Actuation with pulsed magnetic field for sensitive analysis |
EP2208531A1 (en) | 2008-12-30 | 2010-07-21 | Atonomics A/S | Distribution of particles in capillary channel by application of magnetic field |
US9599591B2 (en) | 2009-03-06 | 2017-03-21 | California Institute Of Technology | Low cost, portable sensor for molecular assays |
WO2010121223A2 (en) * | 2009-04-17 | 2010-10-21 | California Institute Of Technology | Electromagnetic molecular sensors and methods of using same |
US20120208296A1 (en) | 2009-08-19 | 2012-08-16 | Koninklijke Philips Electronics N.V. | Detection of different target components by cluster formation |
CN102575976B (en) * | 2009-09-28 | 2016-03-30 | 皇家飞利浦电子股份有限公司 | Substance determining apparatus |
WO2011045436A1 (en) | 2009-10-16 | 2011-04-21 | Åmic AB | An assay method and devices involving the use of magnetic particles |
WO2011049044A1 (en) * | 2009-10-19 | 2011-04-28 | 国立大学法人東京工業大学 | Biosensor using magnetic microparticles |
CN102656443B (en) | 2009-12-18 | 2016-01-20 | 皇家飞利浦电子股份有限公司 | Substance determining apparatus |
EP2362219A1 (en) | 2010-02-19 | 2011-08-31 | Nxp B.V. | Sensor measuring method and sensing apparatus |
US20140099663A1 (en) * | 2010-11-15 | 2014-04-10 | Regents Of The University Of Minnesota | Gmr sensor |
US9304130B2 (en) | 2010-12-16 | 2016-04-05 | International Business Machines Corporation | Trenched sample assembly for detection of analytes with electromagnetic read-write heads |
US9040311B2 (en) | 2011-05-03 | 2015-05-26 | International Business Machines Corporation | Calibration assembly for aide in detection of analytes with electromagnetic read-write heads |
US8855957B2 (en) | 2011-05-03 | 2014-10-07 | International Business Machines Corporation | Method for calibrating read sensors of electromagnetic read-write heads |
WO2013078332A1 (en) * | 2011-11-23 | 2013-05-30 | The General Hospital Corporation | Analyte detection using magnetic hall effect |
US9977015B2 (en) * | 2012-05-15 | 2018-05-22 | Massachusetts Institute Of Technology | Systems and methods for detecting molecular interactions using magnetic beads |
RU2653145C2 (en) * | 2012-09-04 | 2018-05-07 | Конинклейке Филипс Н.В. | Sensor device and method of sampling |
US9435800B2 (en) | 2012-09-14 | 2016-09-06 | International Business Machines Corporation | Sample assembly with an electromagnetic field to accelerate the bonding of target antigens and nanoparticles |
KR101517594B1 (en) | 2013-10-16 | 2015-05-04 | (주)타스컴 | Biosensor |
EP3143386A4 (en) * | 2014-05-12 | 2017-11-29 | Qi, Huan | Method and system for analyte sensing |
WO2016151143A1 (en) * | 2015-03-26 | 2016-09-29 | Koninklijke Philips N.V. | Manufacturing of a biosensor cartridge |
EP3290938A1 (en) | 2016-09-05 | 2018-03-07 | Industrial Technology Research Institute | Biomolecule magnetic sensor |
US20180266991A1 (en) * | 2017-03-15 | 2018-09-20 | Qualcomm Incorporated | Magneto-impedance (mi) sensors employing current confinement and exchange bias layer(s) for increased sensitivity |
GB201720162D0 (en) * | 2017-12-04 | 2018-01-17 | Univ Oxford Innovation Ltd | Method |
EP3628071B1 (en) * | 2018-07-27 | 2022-07-06 | Zepto Life Technology, LLC | System and method for sample preparation in gmr-based detection of biomarkers |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003054523A2 (en) * | 2001-12-21 | 2003-07-03 | Koninklijke Philips Electronics N.V. | Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array |
WO2005010543A1 (en) * | 2003-07-30 | 2005-02-03 | Koninklijke Philips Electronics N.V. | On-chip magnetic sensor device with suppressed cross-talk |
WO2005111596A1 (en) * | 2004-05-18 | 2005-11-24 | Koninklijke Philips Electronics N.V. | Magnetic rotation to improve signal-over-background in biosensing |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8701980A (en) * | 1987-08-24 | 1989-03-16 | Catena Product Dev Bv | INDUCTIVE APPROACH SENSOR. |
CA2131003A1 (en) * | 1992-05-26 | 1993-12-09 | Raymond G. Goodwin | Novel cytokine that binds cd30 |
US5981297A (en) * | 1997-02-05 | 1999-11-09 | The United States Of America As Represented By The Secretary Of The Navy | Biosensor using magnetically-detected label |
US6455319B1 (en) * | 1999-05-10 | 2002-09-24 | California Institute Of Technology | Use of spatiotemporal response behavior in sensor arrays to detect analytes in fluids |
US6875621B2 (en) * | 1999-10-13 | 2005-04-05 | Nve Corporation | Magnetizable bead detector |
WO2003054566A1 (en) * | 2001-12-21 | 2003-07-03 | Koninklijke Philips Electronics N.V. | Magnetoresistive sensing device, system and method for determining a density of magnetic particles in fluid |
WO2003102546A2 (en) * | 2002-05-31 | 2003-12-11 | The Regents Of The University Of California | Method and apparatus for detecting substances of interest |
US20050118603A1 (en) * | 2002-10-11 | 2005-06-02 | Ahram Biosystems Inc. | Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer |
US20050095627A1 (en) * | 2003-09-03 | 2005-05-05 | The Salk Institute For Biological Studies | Multiple antigen detection assays and reagents |
-
2006
- 2006-06-12 CN CNA2006800213124A patent/CN101198870A/en active Pending
- 2006-06-12 JP JP2008516478A patent/JP2008544246A/en active Pending
- 2006-06-12 WO PCT/IB2006/051866 patent/WO2006134546A2/en active Application Filing
- 2006-06-12 RU RU2008101786/14A patent/RU2415432C2/en not_active IP Right Cessation
- 2006-06-12 US US11/917,211 patent/US20080206104A1/en not_active Abandoned
- 2006-06-12 EP EP06765725A patent/EP1894009A2/en not_active Withdrawn
- 2006-06-12 BR BRPI0612623A patent/BRPI0612623A2/en not_active IP Right Cessation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003054523A2 (en) * | 2001-12-21 | 2003-07-03 | Koninklijke Philips Electronics N.V. | Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array |
WO2005010543A1 (en) * | 2003-07-30 | 2005-02-03 | Koninklijke Philips Electronics N.V. | On-chip magnetic sensor device with suppressed cross-talk |
WO2005111596A1 (en) * | 2004-05-18 | 2005-11-24 | Koninklijke Philips Electronics N.V. | Magnetic rotation to improve signal-over-background in biosensing |
Also Published As
Publication number | Publication date |
---|---|
RU2415432C2 (en) | 2011-03-27 |
RU2008101786A (en) | 2009-07-27 |
EP1894009A2 (en) | 2008-03-05 |
US20080206104A1 (en) | 2008-08-28 |
CN101198870A (en) | 2008-06-11 |
WO2006134546A2 (en) | 2006-12-21 |
JP2008544246A (en) | 2008-12-04 |
BRPI0612623A2 (en) | 2016-11-29 |
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