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Pseudo arthrosis device

Info

Publication number
WO2006133315A2
WO2006133315A2 PCT/US2006/022178 US2006022178W WO2006133315A2 WO 2006133315 A2 WO2006133315 A2 WO 2006133315A2 US 2006022178 W US2006022178 W US 2006022178W WO 2006133315 A2 WO2006133315 A2 WO 2006133315A2
Authority
WO
Grant status
Application
Patent type
Prior art keywords
figure
device
tab
arthrosis
pseudo
Prior art date
Application number
PCT/US2006/022178
Other languages
French (fr)
Other versions
WO2006133315A3 (en )
Inventor
Brian Bergeron
Reginald Davis
Michael Funk
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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Abstract

A pseudo arthrosis device (20) may be placed in a disc space to provide support for adjacent vertebrae. The device may have an enclosure (22) formed, from a flexible, permeable material. A core may be packed in the enclosure. The core may be compressible and/or flexible. In certain embodiments, the core may include a plurality of elongated members (24). In other embodiments, the core may include ridges or grooves. The enclosure may be placed in an intervertebral space between the adjacent vertebrae such that the core is disposed between the adjacent vertebrae. The pseudo arthrosis device may include a tab (28) designed to couple the enclosure to an adjacent vertebrae.

Description

PSEUDO ARTHROSIS DEVICE

BACKGROUND

1. Field of Invention

The present invention generally relates to spinal implants for alleviating problems in human spines. More particularly, one aspect of the invention relates to an pseudo arthrosis device (or intradiscal stabilization device) that replaces a damaged spinal disc, and another aspect of the invention relates to artificial anterior longitudinal ligaments (ALLs).

2. Description of Related Art

A spinal disc is a shock-absorbing structure located in a space between two adjacent vertebrae in a spine. A spinal disc may deteriorate due to trauma, disease, and/or aging. A deteriorated spinal disc may have diminished shock-absorbing capacity. A deteriorated disc may allow adjacent vertebrae to contact each other. Contact of adjacent vertebrae may result in wear and tear of the vertebrae. Wear and tear of the vertebrae may result in pain (e.g., neck and/or back pain).

Non-surgical treatments to reduce neck and/or back pain may include rest, heat, medication, physical therapy, and chiropractic manipulation. Non-surgical treatments may be ineffective for some patients.

Surgical treatment of a deteriorated spinal disc may include spinal fusion. A spinal fusion treatment may not be successful in some patients. When successful, spinal fusion treatments may result in stiffness and decreased mobility of the patient. Spinal fusion may cause stress on the spine at adjacent vertebral levels. The stress on the spine may create new spinal problems. New spinal problems may result in additional neck and/or back pain.

Surgical alternatives to spinal fusion may include spinal disc replacement. U.S. Patent Nos. 3,567,728 to Stubstad et al.; 5,071,437 to Steffee; 5,320,644 to Baumgaitner; 5,522,899 to Michelson; 5,961,554 to Janson et al.; 5,976,186 to Bao et al.; 6,162,252 to Kuras et al.; 6,206,924 to Timm; 6,214,049 to Gayer et al; and 6,093,205 to McLeod et al., each of which is incorporated by reference as if folly set forth herein, describe devices for surgical treatment of deteriorated and/or damaged spinal discs.

SUMMARY

A pseudo arthrosis device may be a relatively inexpensive, simple device that is easily inserted into the spine to replace a damaged or degenerated disc. The pseudo arthrosis device may be compatible with the human body. In some embodiments, a pseudo arthrosis device may serve as a matrix or scaffold to support growth of body fibers in a patient. Growth of the patient's body fibers may incorporate the device into the patient. Incorporation of the device into the patient may allow the patient's body to repair itself.

In one embodiment, an implant device includes an enclosure that includes a core packed within the enclosure, and a tab. The core includes a plurality of elongated members. The tab is coupled to the enclosure for attaching the implant to a vertebra.

In another embodiment, an implant device includes an enclosure that includes a core packed within the enclosure, and a tab. The core includes at least one groove on a surface of the core. The tab is coupled to the enclosure for attaching the implant device to a vertebra.

Another aspect of the invention relates to artificial anterior longitudinal ligaments. Natural anterior longitudinal ligaments may become degenerate or become damaged in the course of an operation. The artificial anterior longitudinal ligament can provide stability to the spine in such situations. In one embodiment, an artificial ligament implant includes a tab that has elasticity. The tab includes a pair of openings that are configured to couple the tab to a pair of vertebrae. The tab serves as an artificial longitudinal ligament.

BRIEF DESCRIPTION OF THE DRAWINGS

Figure 1 is a perspective view of a pseudo arthrosis device.

Figure 2 is a side view of an elongated member.

Figure 3 is a cross-sectional view taken substantially along plane 3-3 of Figure 2.

Figure 4 is a side view of a pseudo arthrosis device.

Figure 5 is aback view of a pseudo arthrosis device.

Figure 6 is a cross-sectional view taken substantially along plane 6-6 of Figure 4.

Figure 7 is a cross-sectional view taken substantially along plane 7-7 of Figure 5.

Figure 8 is a perspective view of a pseudo arthrosis device with a pliable retainer in an enclosure.

Figure 9 depicts a portion of a spinal column with a deteriorated disc.

Figure 10 depicts a pseudo arthrosis device positioned for insertion into a disc space.

Figure 11 depicts insertion of a pseudo arthrosis device into a disc space.

Figure 12 depicts a pseudo arthrosis device positioned in a disc space. Figure 13 depicts a portion of a spine showing compression of an implanted pseudo arthrosis device when a patient bends backwards.

Figure 14 depicts a portion of a spine showing compression of an implanted pseudo arthrosis device when a patient bends forwards.

Figure 15 depicts a portion of a spine showing compression of a pseudo arthrosis device when a patient leans laterally to the right.

Figure 16 depicts a portion of a spine showing compression of a pseudo arthrosis device when a patient leans laterally to the left.

Figure 17 is an enlarged view showing placement of a pseudo arthrosis device in a disc space.

Figure 18 is a cross-sectional view taken substantially along line 18-18 of Figure 17 showing fibrous ingrowth.

Figure 19 is an enlarged view of an elongated member showing fibrous ingrowth.

Figure 20 is a perspective view of a pseudo arthrosis device with an enclosure containing a core.

Figure 21 is a side view of a pseudo arthrosis device.

Figure 22 is a perspective view of a pseudo arthrosis device that includes a tab and a core.

Figure 23 is a perspective view of a pseudo arthrosis device with openings fitted with grommets. Figures 24A-24H are perspective views of cores for use in pseudo arthrosis devices.

Figures 25-26 show pseudo arthrosis devices positioned in a patient's spine.

Figures 27-28 show a plurality of pseudo arthrosis devices in a multi-level implant application.

Figure 29 is a perspective view of an artificial anterior longitudinal ligament.

Figure 30 is a side view of an artificial anterior longitudinal ligament.

Figure 31 is an artificial anterior longitudinal ligament positioned in a patient's body.

Figure 32 shows a plurality of artificial anterior longitudinal ligaments in a multi-level implant application.

Figure 33 is a perspective view of an alternative embodiment of an artificial anterior longitudinal ligament.

Figure 34 shows the artificial anterior longitudinal ligament of Figure 33 positioned in a patient's body.

Figure 35 shows a plurality of the artificial anterior longitudinal ligaments of Figure 33 in a multi-level implant application.

Figure 36 shows an alternative application of the artificial anterior longitudinal ligament of Figure 33. Figure 37 shows an alternative application of the artificial anterior longitudinal ligament of Figure 33 in a multi-level implant.

While the invention may be susceptible to various modifications and alternative forms, specific embodiments thereof are shown by way of example in the drawings and will herein be described in detail. The drawings may not be to scale. It should be understood that the drawings and detailed description thereto are not intended to limit the invention to the particular form disclosed, but to the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the present invention as defined by the appended claims.

DETAILED DESCRIPTION OF EMBODIMENTS

Figure 1 depicts pseudo arthrosis device 20 with enclosure 22. Enclosure 22 may be formed from a non-allergenic, biocompatible material. The material may be flexible and/or permeable. The material may include, but is not limited to, synthetic fabrics such as

Dacron®, Proline Mesh®, and Goretex®. Enclosure 22 may have a cross-sectional shape corresponding to a cross-sectional shape of an intervertebral space between two adjacent vertebrae in a human spine. Enclosure 22 may be in the form of a tube, a sleeve, an envelope, or other suitable configuration.

As shown in Figure 1, enclosure 22 may include a plurality of elongated members 24. Elongated members 24 may be compressible and/or flexible. Elongated members 24 may be made of biocompatible materials including, but not limited to, polyethylene, high density polyethylene, ultra high density polyethylene, and various fluorinated polymers. Advantageously, a pseudo arthrosis device including a plurality of elongated members 24 may offer more adaptability, compressibility, and/or flexibility than a device formed of a single piece of substantially the same material.

Longitudinal placement of elongated members 24 in enclosure 22 may allow pseudo arthrosis device 20 to function as a compressible, flexible body. Since the compressibility and flexibility arise from a plurality of elongated members 24, pseudo arthrosis device 20 may provide greater local adaptation to stress between vertebrae than a single deforrnable piece of material. Flexibility of elongated members 24 and enclosure 22 may allow movement in non- longitudinal directions (e.g., bending and rotation) relative to axes of elongated members 24.

In some embodiments, elongated members 24 may be solid rods. In certain embodiments, elongated members 24 may be hollow tubes. For example, an outer diameter of hollow elongated member 24 may range from about 0.5 mm to about 3.0 mm. An inner diameter of hollow elongated member 24 may range from about 0.25 mm to about 2.0 mm. In an embodiment, elongated member 24 may have a wall thickness of about 1 mm.

Figure 2 depicts hollow elongated member 24 with a plurality of spaced-apart perforations 26. Flexibility of elongated member 24 may be a function of wall thickness of the elongated member and number and size of perforations 26. Perforations 26 may increase flexibility of solid as well as hollow elongated members 24. A length of elongated member 24 may be chosen to achieve desired intervertebral spacing and/or desired flexibility. Figure 3 depicts a cross-sectional view of hollow elongated member 24 with perforations 26 taken substantially along plane 3-3 of Figure 2.

As shown in Figure 1, pseudo arthrosis device 20 may include at least one tab 28. Tab

28 may be of any suitable size, shape, or configuration to couple pseudo arthrosis device 20 to a vertebra. In some embodiments, tab 28 may be an integral part of pseudo arthrosis device 20. In other embodiments, tab 28 may be coupled to enclosure 22. In some embodiments, tab 28 may extend substantially perpendicularly upward from enclosure 22. In other embodiments, tab 28 may extend substantially perpendicularly downward from enclosure 22. In certain embodiments, tab 28 may extend substantially perpendicularly upward and downward from enclosure 22. Alternatively, a first tab 28 may extend substantially perpendicularly upward from enclosure 22 and a second tab 28 may extend substantially perpendicularly downward from enclosure 22. In certain embodiments, enclosure 22 and tab 28 may be made of substantially the same material. Tab 28 may include at least one opening 30. Opening 30 may be reinforced with a grommet. A grommet used to reinforce opening 30 may be made of titanium or any other durable biocompatible material. In an embodiment, pseudo arthrosis device 20 may be secured to a vertebra by a connector or fastener inserted through opening 30. In certain embodiments, a connector may be a threaded screw. Alternatively, tab 28 may be connected to a vertebra by methods including the use of, but not limited to the use of, sutures, staples, barbs, and/or adhesive.

Figure 4 depicts a side view of pseudo arthrosis device 20 with enclosure 22 and tab

28. Figure 5 depicts a back view of pseudo arthrosis device 20 with enclosure 22, tab 28, and openings 30.

Figure 6 depicts a cross-sectional view of pseudo arthrosis device 20 taken substantially along plane 6-6 of Figure 4. Figure 7 depicts a cross-sectional view of pseudo arthrosis device 20 taken substantially along plane 7-7 of Figure 5. Figures 6 and 7 depict a plurality of elongated members 24 placed longitudinally in enclosure 22 with coupled tab 28. In the embodiment shown in Figure 7, enclosure 22 has top 32 and bottom 34 to promote retention of elongated members 24 in the enclosure. In some embodiments, top 32 and/or bottom 34 may be made of bioabsorbable material (e.g., Surgicel).

In some embodiments, such as the embodiment shown in Figure 8, pliable retainer 36 may be located transversely in enclosure 22 of pseudo arthrosis device 20. Pliable retainer 36 may have a plurality of spaced-apart holes 38. Elongated members may be positioned securely in holes 38 (e.g., with a friction fit). Elongated members in holes 38 may be retained in an upright packed condition (oriented longitudinally) when pseudo arthrosis device 20 is inserted into a disc space between adjacent vertebrae.

In other embodiments, such as the embodiment shown in Figure 20, rather than elongated members 24, a core 60 may be used in device 20. Core 60 is made of viscoelastic material, such as flexible polymers, hydrogels, collagen, and the like. Generally, core 60 may be made of biocompatible materials. Core 60 provides adaptability, compressibility, pliability and/or flexibility as an artificial disc when inserted in the intervertebral space in a spine. Core 60 may have a plurality of elongated members, columns, walls, bore holes, grooves, and/or dimples, as described below in detail.

Figure 21 shows a side view of an illustrative embodiment of a pseudo arthrosis device 20. In this embodiment, enclosure 22 forms a jacket around core 60 (core 60 packed within enclosure 22). Similar to the configuration shown in Figure 7, enclosure 22 has top 32 and bottom 34 to promote retention of core 60 in the enclosure.

Tab 28 and enclosure 22 may generally have the configurations and be made of the same materials described above. In the illustrative embodiment shown in Figure 20, tab 28 has a first portion or tab that extends upward from enclosure 22, and a second portion or tab that extends downward from enclosure 22. Furthermore, tab 28 includes a plurality of openings 30 on each of the portions that extend upward and downward from enclosure 22.

A variety of numbers, shapes, and configurations of openings 30 may be used, as desired. For example, the embodiment shown in Figure 22 includes a substantially round opening 30 in each of the upward and downward portions of tab 28. As another example, the embodiment shown in Figure 23 uses grommets 65 in each of the openings in the tab. As yet another example, openings 30 may have an elongated shape, similar to the shape of a button hole (see Figures 27 and 28 and their corresponding descriptions).

In some embodiments, as shown for example in Figure 22, core 60 is coupled to tab 28 without the use of an enclosure. In other embodiments, tab 28 and enclosure 22 may have a one-piece configuration or, alternatively, may be separate pieces coupled together (for example, sewn together, glued together, stapled together, and the like). Figures 24A-24H show illustrative embodiments of core 60 for use in pseudo arthrosis devices. In the embodiment of Figure 24A, core 60 has a plurality of ridges or grooves 70 on its top and bottom surfaces. Ridges 70 have a lateral direction (side-to-side, when implanted in the patient's body). The embodiment of Figure 24B also includes a plurality of ridges or grooves 70 on its top and bottom surfaces. Ridges 70 in the core in Figure 24B, however, have a front-to-back (anterior-to-posterior, when implanted in the patient's body) direction. In yet another configuration (not shown), the ridges on the top and bottom surfaces of core 60 may have differing directions, a mixture of directions, and/or other directions (e.g., diagonal) as desired.

Core 60 in Figure 24C has a plate 75 that couples to an upper portion 80 and lower portion 82 of core 60. The top surface of core 60 (i.e., the top surface of upper portion 80) has a plurality of grooves 85 formed as co-centric circles. The bottom surface of core 60 may have a similar or different arrangement of grooves. Grooves 85 help to promote ingrowth of tissue into core 60.

Core 60 in Figure 24D has a plurality of grooves 85 on its top surface. The plurality of grooves 85 may be co-centric circles. The bottom surface of core 60 may have a similar or different arrangement of grooves. Similar to the core in Figure 24C, grooves 85 help to promote ingrowth of tissue into core 60.

Note that grooves 85 in Figures 24C and 24D may have other features or configurations, such as one or more spirals, as desired. Furthermore, top and bottom surfaces of core 60 may have different features or configurations of grooves 85, as desired (for example, circles on one surface of core 60, and a spiral on another surface).

The cores in Figures 24E and 24F include a plurality of elongated members 24 arranged within an outer portion or shell 90. Outer portion 90 generally surrounds elongated members 24. Elongated members 24 may be integral to core 60, or may be constructed by using a pliable retaining plate (not shown explicitly), similar to the embodiment of Figure 8. Core 60 in Figure 24E has the additional feature of a plurality of dimples or indentations 95 on the top surface of outer portion 90. Indentations 95 promote ingrowth of tissue and help to stabilize the patient's spine. The bottom surface of outer portion 90 may have a similar or different arrangement of indentations, as desired. Note that indentations 95 may have a variety of shapes (round or annular, triangular, rectangular, etc.), configurations (e.g., depth), and arrangements, as desired.

Core 60 in Figure 24G has a plurality of dimples or indentations 95 arranged on its top surface. Indentations 95 help to promote ingrowth of tissue. The bottom surface of outer portion 90 may have a similar or different arrangement of indentations, as desired.

Indentations 95 may have a variety of shapes (round or annular, triangular, rectangular, etc.), configurations (e.g., depth), and arrangements, as desired.

The core in Figure 24H includes a plate 75 and a plurality of elongated members 24. Elongated members 24 may be integral to core 60, or may be constructed by using a pliable retaining plate (not shown explicitly), similar to the embodiment of Figure 8. Elongated members 24 may have a variety of shapes, configurations, and arrangements, as described above.

Note that a core (or cores in multi-level applications, as described below) configuration may be used that allows certain forces in the spine, while limiting or tending to limit other forces. For example, the cores shown in Figures 24A, 24B, and 24H tend to allow translational movements of the affected vertebrae. The cores shown in Figures 24C-24G, however, tend to limit translational movements and provide a more rigid support to the spine. Furthermore, generally, the number, shape, size, type, and arrangement of the various physical attributes of the cores (e.g., the number of ridges, pores, dimples, elongated members, etc.) may be varied to suit a particular application, as desired.

Figures 9-12 depict a method of implanting a pseudo arthrosis device. Figure 9 depicts a portion of a spinal column 40 with deteriorated disc 42 between adjacent vertebrae 44. Deteriorated disc 42 may be removed from spinal column 40 to form disc space 46, as shown in Figure 10.

Figure 10 depicts pseudo arthrosis device 20 with enclosure 22 and tab 28 positioned for insertion into disc space 46 between adjacent vertebrae 44. As shown in Figure 11 , elongated members 24 in enclosure 22 are disposed longitudinally between adjacent vertebrae 44 in disc space 46. In an embodiment, tab 28 may be coupled to adjacent vertebrae 44 with connectors 48. Tab 28 may be sized to secure enclosure 22 to adjacent vertebrae 44 with minimal limitation of vertebral movement. Figure 12 depicts pseudo arthrosis device 20 implanted into spinal column 40. In an embodiment, tab 28 and connectors 48 may secure enclosure 22 of pseudo arthrosis device 20 in disc space 46 between adjacent vertebrae 44.

Figures 13-16 show flexion and compression of elongated members 24 following implantation of pseudo arthrosis device 20 in spinal column 40 of a patient. As the patient bends backwards (Figure 13) or forwards (Figure 14), elongated members 24 proximal to the bend of the spine are compressed while the elongated members distal to the bend of the spine are fully extended. Figures 15 and 16 depict compression of elongated members 24 when a patient leans laterally right and left, respectively. Compression and extension of elongated members 24 may cushion vertebrae of spinal column 40, thereby simulating natural disc function. In some patients, pseudo arthrosis device 20 may reduce wear and tear on vertebrae of a spinal column and thus relieve spinal pain.

Figure 17 depicts pseudo arthrosis device 20 after implantation in a disc space between adjacent vertebrae 44. Figure 18 depicts a cross-sectional view of pseudo arthrosis device 20 taken substantially along line 18-18 in Figure 17. As shown in Figure 18, fibers 50 of a patient may penetrate enclosure 22. Fibers 50 that penetrate enclosure 22 may promote fibrous tissue growth in spaces between elongated members 24. Normal movement of the patient and flexibility of pseudo arthrosis device 20 may inhibit conversion of fibrous tissue growth in enclosure 22 into bone. Figure 19 depicts growth of fibers 50 through perforations 26 in elongated member 24. In an embodiment, fibers 50 may grow longitudinally through hollow elongated member 24. Over time, pseudo arthrosis device 20 may be incorporated into scar tissue formed from fibrous ingrowth of a patient. In certain embodiments, pseudo arthrosis device 20 may advantageously function as a scaffold or matrix to promote natural body repair by fibrous ingrowth.

Figures 25-28 show illustrative embodiments of pseudo arthrosis device 20, including core 60, implanted within a spine. Figures 25-26 show implants for a single level, whereas Figures 27-28 illustrate implants for multiple levels.Note that the figures show two-level or three-level applications as illustrative examples, and that the disclosed implants may be used generally in multi-level applications involving different numbers of levels.

Referring to Figure 25, pseudo arthrosis device 20 couples to vertebrae 11OA and HOB. In the embodiment shown, pseudo arthrosis device 20 has openings 30 fitted with grommets 65. A pair of screws 105 fasten the upper and lower parts of tab 28 to vertebrae HOA and 11OB, respectively. In the embodiment shown in Figure 26, screws 105 (or other suitable fastener) fasten the upper and lower parts of tab 28 to vertebrae HOA and HOB, respectively, without the use of grommets.

Figure 27 shows two pseudo arthrosis devices, 2OA and 2OB, in a multi-level implant, involving vertebrae 11 OA-11OC. Note that one of the openings for pseudo arthrosis device 2OA may overlap with one of the openings for pseudo arthrosis device 20. In such a situation, one of the pseudo arthrosis devices may use an opening without a grommet 65, such as opening 3OA of pseudo arthrosis device 2OA. Opening 3OA provides a lower profile for the two overlapping openings of pseudo arthrosis devices 2OA and 20B. Opening 3OA may have a variety of desired shapes, sizes, and arrangements, such as an elongated shape, similar to a button hole. Opening 3OA may also have woven edges to provide additional strength and resist tearing. Figure 28 shows a multi-level implant with three pseudo arthrosis devices 20A-20C coupled to vertebrae 11 OA-11OD. Note that each of pseudo arthrosis devices 2OA and 2OB has an opening (30A and 3OB, respectively) without a grommet. Opening 30A of pseudo arthrosis device 2OA overlaps with the upper opening of pseudo arthrosis device 20, whereas opening 30B of pseudo arthrosis device 20B overlaps with the upper opening of pseudo arthrosis device 20C. Openings 3OA and 30B lack grommets in order to provide a lower profile for the implant.

Another aspect of the invention relates to artificial replacements for anterior longitudinal ligaments (ALLs). An artificial anterior longitudinal ligament may replace and/or reinforce the function of the patient's natural anterior longitudinal ligament. With the introduction of an interbody implant from an anterior approach for fusion devices or motion- preservation devices, the anterior longitudinal ligament is disrupted. The artificial anterior longitudinal ligament restores the tension band in extension in such a situation. Furthermore, when used with an interbody device (e.g., cores 60 described above), the artificial anterior longitudinal ligament prevent expulsion of an interbody device from the spine. The artificial anterior longitudinal ligament may be used for both fusion and non-fusion applications.

The artificial anterior longitudinal ligament may provide stabilization of other implants and interbody devices. In illustrative embodiments, the implant serves as a tension band to replace the function of the anterior longitudinal ligament and provide mechanical stability. The artificial anterior longitudinal ligament may act as a scaffold for ligamental tissue growth and promote ingrowth of tissue.

The artificial anterior longitudinal ligament is a tension and scaffold band or tab, such as tab 28 of the pseudo arthrosis devices described above, and may be made of similar materials. The band is secured to at least one vertebral body above and below the affected level. It can be used with or without fixation to an interbody device, such as an artificial disc. As an example, tab 28 in the embodiment in Figure 22 may either be used as a standalone artificial anterior longitudinal ligament, or as an artificial anterior longitudinal ligament coupled to core 60, which serves as an interbody device. The implant could be attached with permanent or resorbable screws, anchors, sutures, bioglue, staples, or with other fastening methods, as desired.

Figure 29 shows an embodiment of an artificial anterior longitudinal ligament. The artificial anterior longitudinal ligament includes tab 28, having elasticity, with openings 30 for coupling to the vertebrae, as described above. Openings 30 may have a variety of shapes, configurations, and arrangements, as described above.

Tab 28 may include inter-woven elastic material that provides elasticity to it. The tab can therefore limit extension and provide stability to the patient's spine. Figure 30 shows a side view of an illustrative embodiment of tab 28. Tab 28 may include an inter-woven band 120. Band 120 may be made of any suitable material that provides elasticity to tab 28. Alternatively, tab 28 may be made using elastic materials, or may enclose an elastic band.

Figure 31 shows an artificial anterior longitudinal ligament coupled to a patient's vertebrae. Tab 28 has two openings 30, each aligned with a respective one of vertebrae 11OA and HOB. Screws 105 (or other desired suitable fastener) couples tab 28 to vertebrae HOA, 110B.

Note that, as desired, one may use a plurality of tabs 28 (with the respective openings 30 aligned between neighboring tabs 28) in multi-level applications, as shown, for example, in Figure 32. Using a suitable fastener (such as screws 105 shown as an example), tab 28A couples to vertebrae HOA and 11OB, and tab 28B couples to vertebrae 11OB and 11OC. Tab 28A has two openings 30A and 3OB. Upper opening 3OA couples to vertebrae 11OA, and lower opening 30B couples to vertebrae 11OB. Tab 28B also has two openings, an upper opening (not shown explicitly), and a lower opening 3OC. The upper opening of tab 28B aligns with the lower opening 3OB of tab 28 A and shares a common fastener. Figure 33 shows another embodiment of an artificial anterior longitudinal ligament. In this embodiment, tab 28 has an "inverted Y" configuration, with an upper part 28A and a pair of lower parts 28B. Upper part 28A and each of lower parts 28B has an opening 30. Note that the embodiment shown in Figure 33 may be used as part of a pseudo arthrosis device by coupling an enclosure (including a core) to tab 28, or fabricating the tab integrally to the enclosure, as desired. In this application, the enclosure may include one of the cores 60 described above.

Figure 34 shows the artificial anterior longitudinal ligament of Figure 33 implanted in the patient's body. Upper part 28A of tab 28 couples to one vertebra 11OA via fastener 105A. Lower parts 28B of tab 28 are arranged in a crossed configuration, such that their respective openings 30 align with one another, and couple to vertebra 11OB using fastener 105C.

Figure 35 shows a multi-level application of the artificial anterior longitudinal ligament of Figure 33. In this configuration, tab 28A couples to vertebrae HOA and 11OB using fasteners 105A and 105B, respectively. The lower parts of tab 28A align with the upper part of tab 28 and may use a common fastener. Thus, tab 28B couples to vertebrae HOB and HOC using fasteners 105B and 105C, respectively.

Figures 36 and 37 show further applications of the artificial anterior longitudinal ligament of Figure 33 in single-level and multi-level situations, respectively. Unlike Figures 34 and 35, the lower parts of tabs 28 (single-level application in Figure 36) and tabs 28A and 28B (multi-level application in Figure 37) are not crossed. Thus, the lower parts of the tabs do not share a common fastener.

In this patent, certain U.S. patents, U.S. patent applications, and other materials (e.g., articles) have been incorporated by reference. The text of such U.S. patents, U.S. patent applications, and other materials is, however, only incorporated by reference to the extent that no conflict exists between such text and the other statements and drawings set forth herein. In the event of such conflict, then any such conflicting text in such incorporated by reference U.S. patents, U.S. patent applications, and other materials is specifically not incorporated by reference in this patent.

Further modifications and alternative embodiments of various aspects of the invention will be apparent to those skilled in the art in view of this description. Accordingly, this description is to be construed as illustrative only and is for the purpose of teaching those skilled in the art the general manner of carrying out the invention. It is to be understood that the forms of the invention shown and described herein are to be taken as examples of embodiments. Elements and materials may be substituted for those illustrated and described herein, parts and processes may be reversed, and certain features of the invention may be utilized independently, all as would be apparent to one skilled in the art after having the benefit of this description of the invention. Changes may be made in the elements described herein without departing from the spirit and scope of the invention as described in the following claims.

Claims

WHAT IS CLAIMED IS:
1. An implant device, comprising: an enclosure comprising a core packed within the enclosure, wherein the core comprises a plurality of elongated members; and at least one tab coupled to the enclosure for attaching the implant device to a vertebra.
2. The device of claim 1, wherein the enclosure comprises a flexible, permeable material.
3. The device of claim 1, wherein the core is flexible.
4. The device of claim 1, wherein the enclosure comprises a top.
5. The device of claim 1, wherein the enclosure comprises a bottom.
6. The device of claim 1 , wherein the enclosure comprises a top and a bottom.
7. The device of claim 1, wherein the core further comprises an outer portion surrounding the plurality of elongated members.
8. The device of claim 7, wherein a surface of the outer portion of the core comprises a plurality of indentations.
9. The device of claim 1, wherein the core further comprises a plate, and wherein the plurality of elongated members couple to the plate.
10. An implant device, comprising: an enclosure comprising a core packed within the enclosure, wherein the core comprises at least one groove on a surface of the core; and at least one tab coupled to the enclosure for attaching the implant device to a vertebra.
11. The device of claim 10, wherein the enclosure comprises a flexible, permeable material.
12. The device of claim 10, wherein the core is flexible.
13. The device of claim 10, wherein the at least one groove is disposed laterally on the surface of the core.
14. The device of claim 10, wherein the at least one groove is disposed on the surface of the core in an anterior-to-posterior direction.
15. The device of claim 10, wherein the at least one groove comprises a spiral.
16. The device of claim wherein the at least one groove comprises a plurality of co-centric circles.
17. An artificial ligament implant, comprising a tab having elasticity, wherein the tab comprises first and second openings configured to couple the tab to first and second vertebrae as an artificial longitudinal ligament.
18. The artificial ligament implant of claim 17, wherein the tab comprises inter-woven elastic material.
19. The artificial ligament implant of claim 17, wherein the tab comprises an elastic band.
20. The artificial ligament implant of claim 17, wherein the tab further couples to an artificial disc disposed between the first and second vertebrae.
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EP1887989A2 (en) 2008-02-20 application
US20060129242A1 (en) 2006-06-15 application
WO2006133315A3 (en) 2007-04-05 application

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