WO2006121737A3 - Methods and instruments for assessing bone fracture risk - Google Patents

Methods and instruments for assessing bone fracture risk Download PDF

Info

Publication number
WO2006121737A3
WO2006121737A3 PCT/US2006/017035 US2006017035W WO2006121737A3 WO 2006121737 A3 WO2006121737 A3 WO 2006121737A3 US 2006017035 W US2006017035 W US 2006017035W WO 2006121737 A3 WO2006121737 A3 WO 2006121737A3
Authority
WO
WIPO (PCT)
Prior art keywords
bone
instruments
methods
fracture risk
test probe
Prior art date
Application number
PCT/US2006/017035
Other languages
French (fr)
Other versions
WO2006121737A2 (en
Inventor
Paul Hansma
Douglas Rehn
Georg Fantner
Patricia Turner
Original Assignee
Univ California
Paul Hansma
Douglas Rehn
Georg Fantner
Patricia Turner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Paul Hansma, Douglas Rehn, Georg Fantner, Patricia Turner filed Critical Univ California
Priority to CA2607146A priority Critical patent/CA2607146C/en
Priority to AU2006244518A priority patent/AU2006244518A1/en
Priority to CN2006800144618A priority patent/CN101166464B/en
Priority to EP06752167A priority patent/EP1885272A4/en
Priority to JP2008510178A priority patent/JP4918086B2/en
Publication of WO2006121737A2 publication Critical patent/WO2006121737A2/en
Publication of WO2006121737A3 publication Critical patent/WO2006121737A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4504—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/40—Investigating hardness or rebound hardness
    • G01N3/42—Investigating hardness or rebound hardness by performing impressions under a steady load by indentors, e.g. sphere, pyramid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4504—Bones
    • A61B5/4509—Bone density determination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0001—Type of application of the stress
    • G01N2203/0003—Steady
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0014—Type of force applied
    • G01N2203/0016—Tensile or compressive
    • G01N2203/0019—Compressive
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/006—Crack, flaws, fracture or rupture
    • G01N2203/0062—Crack or flaws
    • G01N2203/0064—Initiation of crack
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0076—Hardness, compressibility or resistance to crushing
    • G01N2203/0078—Hardness, compressibility or resistance to crushing using indentation
    • G01N2203/0082—Indentation characteristics measured during load
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0089—Biorheological properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Methods and instruments for assessing bone, for example fracture risk, in a subject in which a test probe is inserted through the skin of the subject so that the test probe contacts the subject's bone and the resistance of the test bone to microscopic fracture by the test probe is determined. Macroscopic bone fracture risk is assessed by measuring the resistance of the bone to microscopic fractures caused by the test probe. The microscopic fractures are so small that they pose negligible health risks. The instrument may also be useful in characterizing other materials, especially if it is necessary to penetrate a layer to get to the material to be characterized.
PCT/US2006/017035 2005-05-05 2006-05-03 Methods and instruments for assessing bone fracture risk WO2006121737A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2607146A CA2607146C (en) 2005-05-05 2006-05-03 Methods and instruments for assessing bone fracture risk
AU2006244518A AU2006244518A1 (en) 2005-05-05 2006-05-03 Methods and instruments for assessing bone fracture risk
CN2006800144618A CN101166464B (en) 2005-05-05 2006-05-03 Instruments for assessing bone fracture risk
EP06752167A EP1885272A4 (en) 2005-05-05 2006-05-03 Methods and instruments for assessing bone fracture risk
JP2008510178A JP4918086B2 (en) 2005-05-05 2006-05-03 Diagnostic instrument for assessing bone

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67883005P 2005-05-05 2005-05-05
US60/678,830 2005-05-05

Publications (2)

Publication Number Publication Date
WO2006121737A2 WO2006121737A2 (en) 2006-11-16
WO2006121737A3 true WO2006121737A3 (en) 2008-01-03

Family

ID=37397087

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/017035 WO2006121737A2 (en) 2005-05-05 2006-05-03 Methods and instruments for assessing bone fracture risk

Country Status (6)

Country Link
EP (1) EP1885272A4 (en)
JP (1) JP4918086B2 (en)
CN (1) CN101166464B (en)
AU (1) AU2006244518A1 (en)
CA (1) CA2607146C (en)
WO (1) WO2006121737A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008156515A2 (en) * 2007-04-03 2008-12-24 The Regents Of The University Of California Improved methods and instruments for materials testing
EP2180833A4 (en) * 2007-08-20 2013-03-13 Univ California Methods and instruments for measuring tissue mechanical properties
US9155500B2 (en) 2010-03-23 2015-10-13 Geisinger Clinic Diagnostic device for determining mechanical integrity of bone
WO2012015592A2 (en) 2010-07-28 2012-02-02 The Regents Of The University Of California Method and device for reference point indentation without a reference probe
US9149291B2 (en) 2012-06-11 2015-10-06 Tenex Health, Inc. Systems and methods for tissue treatment
US11406415B2 (en) 2012-06-11 2022-08-09 Tenex Health, Inc. Systems and methods for tissue treatment
US9925068B2 (en) 2014-05-30 2018-03-27 Treace Medical Concepts, Inc. Bone harvester and bone marrow removal system and method
US9962181B2 (en) 2014-09-02 2018-05-08 Tenex Health, Inc. Subcutaneous wound debridement
ES2684635T3 (en) * 2015-07-20 2018-10-03 W & H Dentalwerk Bürmoos GmbH Medical device, particularly dental, to determine the quality of a bone
CN105054937A (en) * 2015-08-12 2015-11-18 温州经济技术开发区滨海志杰机电产品设计工作室 Silicon carbide medical cursor with inclined grooves in four sides and retractable slide ball
JP6924984B2 (en) * 2017-03-28 2021-08-25 帝人メディカルテクノロジー株式会社 Bone hardness measuring instrument
IT201700057559A1 (en) * 2017-05-26 2018-11-26 European Mft Of Expanded Polystyrene DEVICE AND METHOD FOR THE CHARACTERIZATION OF THE MECHANICAL PROPERTIES OF EXPANDED MATERIALS, IN PARTICULAR OF POLYSTYRENE, OR POLYSTYRENE, EXPANDED.
CN109008953B (en) * 2018-05-24 2021-07-30 中孚医疗（深圳）有限公司 Bone mechanical property measuring method
CN113116337B (en) * 2019-02-25 2022-05-13 无锡市第二人民医院 Automatic whole body examination data acquisition method
WO2021072546A1 (en) * 2019-10-17 2021-04-22 University Of Ottawa Force measurement device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766137A (en) * 1995-09-20 1998-06-16 Axiom Co., Ltd. Frequency deviation detecting circuit and measuring apparatus using the frequency deviation detecting circuit
US5897510A (en) * 1995-06-09 1999-04-27 Activator Methods, Inc. Method for determining the dynamic biomechanical characteristics of a musculoskeletal structure and for treatment of musculoskeletal disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2391695A1 (en) * 1977-05-26 1978-12-22 Boyer Edmond Durometer for medical use - has air operated piston with pressure indicator and cone penetrator providing reading on dial gauge
US5503162A (en) * 1992-04-21 1996-04-02 Board Of Regents, University Of Texas System Arthroscopic cartilage evaluator and method for using the same
JPH06237933A (en) * 1993-02-19 1994-08-30 Noritoshi Nakabachi Property measuring unit
JPH08182681A (en) * 1994-12-28 1996-07-16 A & D Co Ltd Bone strength measuring device
US5701913A (en) * 1995-02-03 1997-12-30 University Technologies International Inc. Tissue softness probe
JP4425993B2 (en) * 1996-08-23 2010-03-03 オステオバイオロジックス， インコーポレイテッド Gripping material tester
JP3951257B2 (en) * 1996-11-08 2007-08-01 株式会社井元製作所 Muscle hardness meter
JPH11104087A (en) * 1997-10-02 1999-04-20 Sekisui Chem Co Ltd Bone frequency measuring method
JPH11128181A (en) * 1997-11-04 1999-05-18 Sekisui Chem Co Ltd Bone strength evaluation method
JPH11137526A (en) * 1997-11-11 1999-05-25 Sekisui Chem Co Ltd Bone strength measuring method
JPH11169352A (en) * 1997-12-12 1999-06-29 Japan Science & Technology Corp Bone strength measuring method and equipment
US6068604A (en) * 1998-04-09 2000-05-30 Smith & Nephew, Inc. Cartilage indentor instrument
DE10018769A1 (en) * 2000-04-15 2001-10-31 Tuhh Tech Gmbh Intraoperative bone quality evaluation method, uses measurement of force required for insertion of measuring probe in bone

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5897510A (en) * 1995-06-09 1999-04-27 Activator Methods, Inc. Method for determining the dynamic biomechanical characteristics of a musculoskeletal structure and for treatment of musculoskeletal disorders
US5766137A (en) * 1995-09-20 1998-06-16 Axiom Co., Ltd. Frequency deviation detecting circuit and measuring apparatus using the frequency deviation detecting circuit

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1885272A4 *

Also Published As

Publication number Publication date
CN101166464A (en) 2008-04-23
JP2008539884A (en) 2008-11-20
CA2607146C (en) 2015-07-14
EP1885272A4 (en) 2009-05-27
CN101166464B (en) 2010-12-01
EP1885272A2 (en) 2008-02-13
CA2607146A1 (en) 2006-11-16
AU2006244518A1 (en) 2006-11-16
WO2006121737A2 (en) 2006-11-16
JP4918086B2 (en) 2012-04-18

Similar Documents

Publication Publication Date Title
WO2006121737A3 (en) Methods and instruments for assessing bone fracture risk
WO2008156515A3 (en) Improved methods and instruments for materials testing
TW200730129A (en) Method and apparatus for point of care osmolarity testing
WO2007002579A3 (en) Assay cartridges and methods for point of care instruments
GB2417569B (en) Combined test instrument probe and voltage detector
EP2634574A3 (en) A cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
PL1901650T3 (en) Probe for measuring the impedance of human or animal body tissue
EP2520935A3 (en) Organ-specific proteins and methods of their use
EP1848999A4 (en) Fecal sample test device and methods of use
TWI368740B (en) Probe card,method of making the same and test environment for testing integrated circuits
DE60132910D1 (en) KIT FOR OBTAINING AN ENDOARTERIAL BIOPSY TEST
MX2007005053A (en) Method of examining alzheimer s disease and diagnostic reagent.
EP1870714A4 (en) Microstructure probe card, and microstructure inspecting device, method, and computer program
WO2008091814A3 (en) Assessment of asthma and allergen-dependent gene expression
DE502006007177D1 (en) Apparatus and method for measuring geometric properties of medical treatment devices, in particular for the automatic verification, calibration and measurement of instruments for computer-assisted surgery
MXPA05007067A (en) Analyte measuring system which prevents the reuse of a test strip.
DE602005007134D1 (en) Ultrasound probe and ultrasound diagnostic apparatus
DE112007000683A5 (en) Device for carrying out and testing biological samples with temperature-controlled biological reactions
DE602005017308D1 (en) Examination apparatus with ultrasound probe, ultrasound examination apparatus and examination method with an ultrasound probe
WO2006024466A3 (en) Test device for the in vitro diagnosis of multi-analyte tests and the use thereof
JP2008539884A5 (en)
WO2007114986A3 (en) Cooperative probes and methods of using them
WO2008058014A3 (en) Method and apparatus for noninvasive probe/skin tissue contact sensing
WO2009122024A8 (en) Device and method for micro-elastography
DE60239398D1 (en) HYDROPHILIC DIAGNOSIS DEVICES FOR USE IN THE TESTING OF BIOLOGICAL LIQUIDS

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200680014461.8

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2006244518

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2607146

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 2008510178

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006752167

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: RU