WO2006077085A2 - Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration - Google Patents
Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration Download PDFInfo
- Publication number
- WO2006077085A2 WO2006077085A2 PCT/EP2006/000398 EP2006000398W WO2006077085A2 WO 2006077085 A2 WO2006077085 A2 WO 2006077085A2 EP 2006000398 W EP2006000398 W EP 2006000398W WO 2006077085 A2 WO2006077085 A2 WO 2006077085A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hyaluronic acid
- acid derivative
- stem cells
- injury
- biomaterial
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials For Medical Uses (AREA)
- Polymers & Plastics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0606596-1A BRPI0606596A2 (en) | 2005-01-19 | 2006-01-18 | derived from hyaluronic acid and neural stem cells for sci and pnt regeneration |
AU2006207618A AU2006207618A1 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for SCI and PNT regeneration |
MX2007008668A MX2007008668A (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration. |
CA002604394A CA2604394A1 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration |
PL06700988T PL1838240T3 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration |
SI200632267T SI1838240T1 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration |
DK06700988.6T DK1838240T3 (en) | 2005-01-19 | 2006-01-18 | HYALURONIC ACID DERIVATIVES AND NEURAL STEM CELLS FOR SCI AND PNT REGENERATION |
US11/795,428 US20090202495A1 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic Acid Derivative and Neural Stem Cells for SCI and PNT Regeneration |
EP06700988.6A EP1838240B1 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration |
JP2007550771A JP2008526916A (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivatives and neural stem cells for SCI and PNT regeneration |
ES06700988.6T ES2668355T3 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for the regeneration of SCI and PNT |
US12/470,116 US20100136081A1 (en) | 2005-01-19 | 2009-05-21 | Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration |
US15/668,716 US10702628B2 (en) | 2005-01-19 | 2017-08-04 | Hyaluronic acid derivative and neural stem cells for SCI and PNT regeneration |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64458705P | 2005-01-19 | 2005-01-19 | |
US60/644,587 | 2005-01-19 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/795,428 A-371-Of-International US20090202495A1 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic Acid Derivative and Neural Stem Cells for SCI and PNT Regeneration |
US24590508A Continuation | 2005-01-19 | 2008-10-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006077085A2 true WO2006077085A2 (en) | 2006-07-27 |
WO2006077085A3 WO2006077085A3 (en) | 2006-09-21 |
Family
ID=36463348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2006/000398 WO2006077085A2 (en) | 2005-01-19 | 2006-01-18 | Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration |
Country Status (15)
Country | Link |
---|---|
US (3) | US20090202495A1 (en) |
EP (1) | EP1838240B1 (en) |
JP (1) | JP2008526916A (en) |
KR (1) | KR20070097065A (en) |
CN (1) | CN101106955A (en) |
AU (1) | AU2006207618A1 (en) |
BR (1) | BRPI0606596A2 (en) |
CA (1) | CA2604394A1 (en) |
DK (1) | DK1838240T3 (en) |
ES (1) | ES2668355T3 (en) |
MX (1) | MX2007008668A (en) |
PL (1) | PL1838240T3 (en) |
RU (1) | RU2007127416A (en) |
SI (1) | SI1838240T1 (en) |
WO (1) | WO2006077085A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2427167A1 (en) * | 2009-05-04 | 2012-03-14 | Neostem, Inc | Method and composition for restoration of age-related tissue loss in the face or selected areas of the body |
WO2016097448A1 (en) * | 2014-12-16 | 2016-06-23 | Universitat Politècnica De València | Biohybrid for the use thereof in the regeneration of neural tracts |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5867797B2 (en) * | 2011-05-27 | 2016-02-24 | 国立大学法人京都大学 | Cell culture substrate for inducing differentiation of dopaminergic neurons |
KR101865781B1 (en) * | 2016-11-10 | 2018-06-11 | (주)헵틸와이 | Hydrogel comprising oxidized polysaccharide and amine-modified hyaluronic acid for wound dressings and manufacturing method thereof |
WO2019135216A1 (en) | 2018-01-02 | 2019-07-11 | Cartiheal (2009) Ltd. | Implantation tool and protocol for optimized solid substrates promoting cell and tissue growth |
CN115770324B (en) * | 2022-11-30 | 2024-01-16 | 苏州大学附属第一医院 | Preparation method of living body electrostatic spinning bracket for promoting nerve regeneration |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6482231B1 (en) * | 1995-11-20 | 2002-11-19 | Giovanni Abatangelo | Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative |
US20040037810A1 (en) * | 2000-05-03 | 2004-02-26 | Dennis Von Heimburg | Biomaterials comprised of preadipocyte cells for soft tissue repair |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU697045B2 (en) * | 1995-01-16 | 1998-09-24 | Baxter International Inc. | Self-supporting sheet-like material of cross-linked fibrin for preventing post- operative adhesions |
US6361996B1 (en) * | 1997-05-07 | 2002-03-26 | University Of Utah Research Foundation | Neuroepithelial stem cells and glial-restricted intermediate precursors |
WO1999058042A2 (en) * | 1998-05-14 | 1999-11-18 | Abraham Shahar | Specially devised neuronal implants for reconstruction of damaged central nervous system |
-
2006
- 2006-01-18 ES ES06700988.6T patent/ES2668355T3/en active Active
- 2006-01-18 US US11/795,428 patent/US20090202495A1/en not_active Abandoned
- 2006-01-18 PL PL06700988T patent/PL1838240T3/en unknown
- 2006-01-18 JP JP2007550771A patent/JP2008526916A/en not_active Withdrawn
- 2006-01-18 MX MX2007008668A patent/MX2007008668A/en unknown
- 2006-01-18 EP EP06700988.6A patent/EP1838240B1/en active Active
- 2006-01-18 RU RU2007127416/15A patent/RU2007127416A/en not_active Application Discontinuation
- 2006-01-18 DK DK06700988.6T patent/DK1838240T3/en active
- 2006-01-18 AU AU2006207618A patent/AU2006207618A1/en not_active Abandoned
- 2006-01-18 SI SI200632267T patent/SI1838240T1/en unknown
- 2006-01-18 WO PCT/EP2006/000398 patent/WO2006077085A2/en active Application Filing
- 2006-01-18 CA CA002604394A patent/CA2604394A1/en not_active Abandoned
- 2006-01-18 KR KR1020077016327A patent/KR20070097065A/en not_active Application Discontinuation
- 2006-01-18 CN CNA2006800025040A patent/CN101106955A/en active Pending
- 2006-01-18 BR BRPI0606596-1A patent/BRPI0606596A2/en not_active IP Right Cessation
-
2009
- 2009-05-21 US US12/470,116 patent/US20100136081A1/en not_active Abandoned
-
2017
- 2017-08-04 US US15/668,716 patent/US10702628B2/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6482231B1 (en) * | 1995-11-20 | 2002-11-19 | Giovanni Abatangelo | Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative |
US20040037810A1 (en) * | 2000-05-03 | 2004-02-26 | Dennis Von Heimburg | Biomaterials comprised of preadipocyte cells for soft tissue repair |
Non-Patent Citations (3)
Title |
---|
CATTANEO E ET AL: "PROLIFERATION AND DIFFERENTIATION OF NEURONAL STEM CELLS REGULATED BY NERVE GROWTH FACTOR" NATURE (LONDON), vol. 347, no. 6295, 1990, pages 762-765, XP002383793 ISSN: 0028-0836 * |
RADICE M ET AL: "Hyaluronan-based biopolymers as delivery vehicles for bone-marrow-derived mesenchymal progenitors." JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. MAY 2000, vol. 50, no. 2, May 2000 (2000-05), pages 101-109, XP002383895 ISSN: 0021-9304 * |
SEAL B L ET AL: "Polymeric biomaterials for tissue and organ regeneration" MATERIALS SCIENCE AND ENGINEERING R: REPORTS, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 34, no. 4-5, 10 October 2001 (2001-10-10), pages 147-230, XP004305564 ISSN: 0927-796X * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2427167A1 (en) * | 2009-05-04 | 2012-03-14 | Neostem, Inc | Method and composition for restoration of age-related tissue loss in the face or selected areas of the body |
EP2427167A4 (en) * | 2009-05-04 | 2012-12-19 | Neostem Inc | Method and composition for restoration of age-related tissue loss in the face or selected areas of the body |
WO2016097448A1 (en) * | 2014-12-16 | 2016-06-23 | Universitat Politècnica De València | Biohybrid for the use thereof in the regeneration of neural tracts |
Also Published As
Publication number | Publication date |
---|---|
AU2006207618A1 (en) | 2006-07-27 |
SI1838240T1 (en) | 2018-07-31 |
KR20070097065A (en) | 2007-10-02 |
CN101106955A (en) | 2008-01-16 |
ES2668355T3 (en) | 2018-05-17 |
RU2007127416A (en) | 2009-01-27 |
BRPI0606596A2 (en) | 2009-07-07 |
CA2604394A1 (en) | 2006-07-27 |
US10702628B2 (en) | 2020-07-07 |
PL1838240T3 (en) | 2018-09-28 |
EP1838240B1 (en) | 2018-04-11 |
EP1838240A2 (en) | 2007-10-03 |
US20180140741A1 (en) | 2018-05-24 |
DK1838240T3 (en) | 2018-06-18 |
MX2007008668A (en) | 2008-02-11 |
US20100136081A1 (en) | 2010-06-03 |
WO2006077085A3 (en) | 2006-09-21 |
US20090202495A1 (en) | 2009-08-13 |
JP2008526916A (en) | 2008-07-24 |
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