WO2006067103A3 - Process for the preparation of a 2-pyridylethylcarboxamide derivative - Google Patents

Process for the preparation of a 2-pyridylethylcarboxamide derivative Download PDF

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Publication number
WO2006067103A3
WO2006067103A3 PCT/EP2005/056895 EP2005056895W WO2006067103A3 WO 2006067103 A3 WO2006067103 A3 WO 2006067103A3 EP 2005056895 W EP2005056895 W EP 2005056895W WO 2006067103 A3 WO2006067103 A3 WO 2006067103A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
derivative
pyridylethylcarboxamide derivative
general formula
pyridylethylcarboxamide
Prior art date
Application number
PCT/EP2005/056895
Other languages
French (fr)
Other versions
WO2006067103A2 (en
Inventor
Frederic Lhermitte
Pierre-Yves Coqueron
Philippe Desbordes
Thomas Himmler
Original Assignee
Bayer Cropscience Sa
Frederic Lhermitte
Pierre-Yves Coqueron
Philippe Desbordes
Thomas Himmler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to KR1020077016637A priority Critical patent/KR101312816B1/en
Priority to DK05823830.4T priority patent/DK1831169T3/en
Priority to MX2007007105A priority patent/MX2007007105A/en
Priority to CN2005800435765A priority patent/CN101080391B/en
Application filed by Bayer Cropscience Sa, Frederic Lhermitte, Pierre-Yves Coqueron, Philippe Desbordes, Thomas Himmler filed Critical Bayer Cropscience Sa
Priority to EP05823830A priority patent/EP1831169B1/en
Priority to BRPI0516905A priority patent/BRPI0516905B1/en
Priority to ES05823830T priority patent/ES2383903T3/en
Priority to AT05823830T priority patent/ATE553083T1/en
Priority to US11/793,561 priority patent/US7790901B2/en
Priority to JP2007547473A priority patent/JP4869251B2/en
Publication of WO2006067103A2 publication Critical patent/WO2006067103A2/en
Publication of WO2006067103A3 publication Critical patent/WO2006067103A3/en
Priority to IL183662A priority patent/IL183662A/en
Priority to US12/847,152 priority patent/US8865908B2/en
Priority to IL217962A priority patent/IL217962A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/68—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/69—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Process for the preparation of a N-[2-(2-pyridinyl)ethyl]carboxamide derivative of general formula (I) or a salt thereof 5 Intermediate of general formula (II) Intermediate of general formula (III).
PCT/EP2005/056895 2004-12-21 2005-12-19 Process for the preparation of a 2-pyridylethylcarboxamide derivative WO2006067103A2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
BRPI0516905A BRPI0516905B1 (en) 2004-12-21 2005-12-19 process for the preparation of an n- [2- (2-pyridinyl) ethyl] carboxamide derivative and compounds
MX2007007105A MX2007007105A (en) 2004-12-21 2005-12-19 Process for the preparation of a 2-pyridylethylcarboxamide derivative.
CN2005800435765A CN101080391B (en) 2004-12-21 2005-12-19 Process for the preparation of a 2-pyridylethylcarboxamide derivative
AT05823830T ATE553083T1 (en) 2004-12-21 2005-12-19 METHOD FOR PRODUCING A 2-PYRIDYLETHYLCARBOXYLIC AMIDE DERIVATIVE
EP05823830A EP1831169B1 (en) 2004-12-21 2005-12-19 Process for the preparation of a 2-pyridylethylcarboxamide derivative
DK05823830.4T DK1831169T3 (en) 2004-12-21 2005-12-19 Process for preparing a 2-pyridylethyl carboxamide derivative
ES05823830T ES2383903T3 (en) 2004-12-21 2005-12-19 Procedure for the preparation of a 2-pyridylethylcarboxamide derivative
KR1020077016637A KR101312816B1 (en) 2004-12-21 2005-12-19 Process for the preparation of a ２-pyridylethylcarboxamide derivative
US11/793,561 US7790901B2 (en) 2004-12-21 2005-12-19 Process for the preparation of a 2-pyridylethylcarboxamide derivative
JP2007547473A JP4869251B2 (en) 2004-12-21 2005-12-19 Method for preparing 2-pyridylethylcarboxamide derivatives
IL183662A IL183662A (en) 2004-12-21 2007-06-04 Process for the preparation of a 2-pyridylethylcarboxamide derivative
US12/847,152 US8865908B2 (en) 2004-12-21 2010-07-30 Process for the preparation of a 2-pyridylethylcarboxamide derivative
IL217962A IL217962A (en) 2004-12-21 2012-02-06 Intermediate useful in the preparation of n-[2-( 2-pyridinyl)ethyl]carboxamide derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04356203.2 2004-12-21
EP04356203 2004-12-21

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/793,561 A-371-Of-International US7790901B2 (en) 2004-12-21 2005-12-19 Process for the preparation of a 2-pyridylethylcarboxamide derivative
US12/847,152 Division US8865908B2 (en) 2004-12-21 2010-07-30 Process for the preparation of a 2-pyridylethylcarboxamide derivative

Publications (2)

Publication Number Publication Date
WO2006067103A2 WO2006067103A2 (en) 2006-06-29
WO2006067103A3 true WO2006067103A3 (en) 2006-11-16

Family

ID=34931762

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/056895 WO2006067103A2 (en) 2004-12-21 2005-12-19 Process for the preparation of a 2-pyridylethylcarboxamide derivative

Country Status (13)

Country Link
US (2) US7790901B2 (en)
EP (1) EP1831169B1 (en)
JP (2) JP4869251B2 (en)
KR (1) KR101312816B1 (en)
CN (1) CN101080391B (en)
AT (1) ATE553083T1 (en)
BR (1) BRPI0516905B1 (en)
DK (1) DK1831169T3 (en)
ES (1) ES2383903T3 (en)
IL (2) IL183662A (en)
MX (1) MX2007007105A (en)
TW (2) TWI370121B (en)
WO (1) WO2006067103A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102522231B1 (en) 2016-12-21 2023-04-14 바이엘 크롭사이언스 악티엔게젤샤프트 Method for producing 2-pyridylethylcarboxamide derivatives

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EP2773203A1 (en) * 2011-11-02 2014-09-10 Bayer Intellectual Property GmbH Compounds with nematicidal activity
EP2606727A1 (en) 2011-12-21 2013-06-26 Bayer CropScience AG Compounds with nematicidal activity
EP2589294A1 (en) 2011-11-02 2013-05-08 Bayer CropScience AG Compounds with nematicidal activity
US20140256728A1 (en) 2011-11-02 2014-09-11 Bayer Intellectual Property Gmbh Compounds with nematicidal activity
EP2606728A1 (en) 2011-12-21 2013-06-26 Bayer CropScience AG Compounds with nematicidal activity
EP2589292A1 (en) 2011-11-02 2013-05-08 Bayer CropScience AG Compounds with nematicidal activity
BR112015000372B1 (en) 2012-07-12 2020-07-28 Nissan Chemical Corporation amide compound replaced by oxime and pest control agent
CN103535362A (en) * 2012-07-13 2014-01-29 陕西美邦农药有限公司 Efficient bactericidal composition
CN103535354A (en) * 2012-07-13 2014-01-29 陕西美邦农药有限公司 Efficient bactericidal composition
CN103535353A (en) * 2012-07-13 2014-01-29 陕西美邦农药有限公司 Efficient bactericidal composition
CN103535355A (en) * 2012-07-13 2014-01-29 陕西美邦农药有限公司 Efficient bactericidal composition
UY35772A (en) 2013-10-14 2015-05-29 Bayer Cropscience Ag NEW PESTICIDED COMPOUNDS
EP3154933B1 (en) * 2014-06-16 2019-03-27 Srf Limited Process for the preparation of 2-(trihalomethyl) benzamide
KR101719565B1 (en) * 2014-10-02 2017-03-24 한국화학연구원 Chlorotrifluoromethylation method of alkene compounds using photoredox catalysis and CF3SO2Cl
JP2021532138A (en) * 2018-07-26 2021-11-25 バイエル、アクチエンゲゼルシャフトBayer Aktiengesellschaft Crystal form of fluopyram
CN108752268A (en) * 2018-08-28 2018-11-06 陕西恒润化学工业有限公司 A kind of 2-（3- chloro-5-trifluoromethylpyridines）Dimethyl malenate and its synthetic method
CN108822024B (en) * 2018-08-28 2021-03-09 陕西恒润化学工业有限公司 Fluopyram and synthetic method thereof
CN110437138B (en) * 2019-08-12 2021-03-02 大连九信精细化工有限公司 Improved synthesis process of fluopyram
CN112979539B (en) * 2021-05-17 2021-07-20 湖南速博生物技术有限公司 Synthesis method of fluopyram intermediate
CN113429338B (en) * 2021-05-20 2023-05-02 陕西泰合利华工业有限公司 Method for synthesizing fluopyram
CN113620867B (en) * 2021-09-03 2023-06-16 内蒙古蓝科生物科技有限公司 Synthesis method of fluopyram
CN114195667A (en) * 2021-11-30 2022-03-18 江西永通科技股份有限公司 Synthesis method of o-trifluoromethyl benzamide

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DE1034644B (en) * 1956-09-26 1958-07-24 Bayer Ag Process for the preparation of acylaminomethyl compounds
EP0061836A2 (en) * 1981-03-19 1982-10-06 Imperial Chemical Industries Plc Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them
WO2001011965A1 (en) * 1999-08-18 2001-02-22 Aventis Cropscience Gmbh Fungicides
WO2004016088A2 (en) * 2002-08-12 2004-02-26 Bayer Cropscience S.A. Novel 2-pyridylethylbenzamide derivative

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JPS5363337A (en) * 1976-11-12 1978-06-06 Nippon Kayaku Co Ltd Benzamide derivs, process for their preparation and herbicides contg.the same as active constituents
DE4138026A1 (en) * 1991-11-19 1993-06-03 Bayer Ag SUBSTITUTED PYRIDINE-4-CARBONIC ACID AMIDES
JP2001213869A (en) * 2000-01-28 2001-08-07 Nippon Bayer Agrochem Co Ltd Isothiazole carboxylic acid derivative and pathogenesis controlling agent
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WO2003099266A2 (en) * 2002-05-23 2003-12-04 Abbott Laboratories Acetamides and benzamides that are useful in treating sexual dysfunction
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TWI368482B (en) * 2003-12-19 2012-07-21 Bayer Sas New 2-pyridinylethylbenzamide derivatives
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Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
DE1034644B (en) * 1956-09-26 1958-07-24 Bayer Ag Process for the preparation of acylaminomethyl compounds
EP0061836A2 (en) * 1981-03-19 1982-10-06 Imperial Chemical Industries Plc Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them
WO2001011965A1 (en) * 1999-08-18 2001-02-22 Aventis Cropscience Gmbh Fungicides
WO2004016088A2 (en) * 2002-08-12 2004-02-26 Bayer Cropscience S.A. Novel 2-pyridylethylbenzamide derivative

Non-Patent Citations (1)

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HASHIMOTO M ET AL: "A FACILE SYNTHESIS OF SUBSTITUTED METHYLAMIDES FROM ACETOXYMETHYLAMIDES", CHEMISTRY EXPRESS, OSAKA, JP, vol. 7, no. 1, 1992, pages 65 - 68, XP001203953, ISSN: 0911-9566 *

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Publication number Priority date Publication date Assignee Title
KR102522231B1 (en) 2016-12-21 2023-04-14 바이엘 크롭사이언스 악티엔게젤샤프트 Method for producing 2-pyridylethylcarboxamide derivatives

Also Published As

Publication number Publication date
ES2383903T3 (en) 2012-06-27
KR20070087668A (en) 2007-08-28
US20100292485A1 (en) 2010-11-18
TWI370121B (en) 2012-08-11
EP1831169B1 (en) 2012-04-11
JP2011236216A (en) 2011-11-24
CN101080391A (en) 2007-11-28
EP1831169A2 (en) 2007-09-12
BRPI0516905A (en) 2008-09-23
JP2008524307A (en) 2008-07-10
WO2006067103A2 (en) 2006-06-29
BRPI0516905B1 (en) 2016-09-20
TW200637822A (en) 2006-11-01
IL217962A0 (en) 2012-03-29
IL217962A (en) 2015-02-26
US8865908B2 (en) 2014-10-21
TW201215594A (en) 2012-04-16
TWI379826B (en) 2012-12-21
DK1831169T3 (en) 2012-07-09
US20080086008A1 (en) 2008-04-10
CN101080391B (en) 2010-09-22
JP5559745B2 (en) 2014-07-23
IL183662A0 (en) 2007-09-20
IL183662A (en) 2012-06-28
KR101312816B1 (en) 2013-09-27
MX2007007105A (en) 2007-08-08
ATE553083T1 (en) 2012-04-15
JP4869251B2 (en) 2012-02-08
US7790901B2 (en) 2010-09-07

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