WO2005112844A2 - Binocular optical treatment for presbyopia - Google Patents
Binocular optical treatment for presbyopia Download PDFInfo
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- WO2005112844A2 WO2005112844A2 PCT/US2005/017991 US2005017991W WO2005112844A2 WO 2005112844 A2 WO2005112844 A2 WO 2005112844A2 US 2005017991 W US2005017991 W US 2005017991W WO 2005112844 A2 WO2005112844 A2 WO 2005112844A2
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- Prior art keywords
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- central zone
- zone
- ablative
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F9/00802—Methods or devices for eye surgery using laser for photoablation
- A61F9/00804—Refractive treatments
- A61F9/00808—Inducing higher orders, e.g. for correction of presbyopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00844—Feedback systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
- A61F2009/00872—Cornea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00885—Methods or devices for eye surgery using laser for treating a particular disease
- A61F2009/00895—Presbyopia
Definitions
- This invention generally relates to methods and systems for providing optical correction. More particularly, the invention provides methods and systems for mitigating or treating presbyopia and other vision conditions.
- Presbyopia is a condition that affects the accommodation properties ofthe eye. As objects move closer to a young, properly functioning eye, the effects of ciliary muscle contraction and zonular relaxation allow the lens ofthe eye to become rounder or more convex, and thus increase its optical power and ability to focus at near distances. Accommodation can allow the eye to focus and refocus between near and far objects.
- Presbyopia normally develops as a person ages, and is associated with a natural progressive loss of accommodation, sometimes referred to as "old sight.”
- the presbyopic eye often loses the ability to rapidly and easily refocus on objects at varying distances. There may also be a loss in the ability to focus on objects at near distances.
- the effects of presbyopia usually become noticeable after the age of 45 years.
- the crystalline lens has often lost almost all elastic properties and has only limited ability to change shape.
- Residual accommodation refers to the amount of accommodation that remains in the eye. A lower degree of residual accommodation contributes to more severe presbyopia, whereas a higher amount of residual accommodation correlates with less severe presbyopia.
- presbyopia has also been treated with bi-focal eyeglasses, where one portion ofthe lens is corrected for distance vision, and another portion ofthe lens is corrected for near vision. When peering down through the bifocals, the individual looks through the portion of the lens corrected for near vision. When viewing distant objects, the individual looks higher, through the portion ofthe bi-focals corrected for distance vision. Thus with little or no accommodation, the individual can see both far and near objects.
- IOLs intra-ocular lenses
- One approach is to provide the individual with monovision, where one eye (usually the primary eye) is corrected for distance- vision, while the other eye is corrected for near- vision.
- monovision the individual may not clearly see objects that are intermediately positioned because the object is out-of-focus for both eyes.
- an individual may have trouble seeing with only one eye, or may be unable to tolerate an imbalance between their eyes.
- other approaches include bilateral correction with either bi-focal or multi-focal lenses. In the case of bi-focal lenses, the lens is made so that both a distant point and a near point can be focused. In the multi-focal case, there exist many focal points between near targets and far targets.
- Surgical treatments have also been proposed for presbyopia.
- Anterior sclerostomy involves a surgical incision into the sclera that enlarges the ciliary space and facilitates movement ofthe lens.
- SEBs scleral expansion bands
- a method for treating presbyopia in a patient involves ablating a central zone of a corneal surface of a first eye ofthe patient to improve the patient's ability to view near objects through the central zone ofthe first eye and ablating a peripheral zone of a corneal surface of a second eye ofthe patient to improve the patient's ability to view near objects through the peripheral zone ofthe second eye.
- the central zone produced during the first ablating step comprises a substantially spherical surface.
- the central zone may comprise a multifocal aspheric surface.
- ablating the central zone ofthe corneal surface ofthe first eye may involve leaving a small central portion ofthe corneal surface untreated, h some embodiments, the ablated central zone may have a diameter scaled to a diameter of a pupil ofthe first eye.
- the ablated central zone may have any desired optical power, but in some embodiments it has an optical power of between about 0.5 and 4.0 Diopters (D), and more preferably between about 1.0 and 3.0 D, and even more preferably an optical power of about 1.75 D.
- D Diopters
- the method further includes ablating a peripheral zone of a corneal surface ofthe first eye to improve the patient's ability to view far objects through the peripheral zone ofthe first eye.
- the peripheral zone of the first eye extends radially outward from an outer boundary ofthe ablated central zone of the first eye to a diameter approximately matching an outer boundary of a pupil ofthe first eye.
- the method may optionally further include ablating a transition zone ofthe corneal surface ofthe first eye, the transition zone extending from an outer boundary ofthe ablated peripheral zone ofthe first eye.
- ablating the peripheral zone of a corneal surface ofthe second eye may involve leaving a central zone ofthe corneal surface ofthe second eye untreated to provide for vision of distant objects through the central zone.
- the method may include ablating a central zone ofthe corneal surface ofthe second eye to improve the patient's ability to view distant objects through the central zone.
- a method for performing laser eye surgery on a patient to treat presbyopia involves: determimng a first ablative shape for a corneal surface, the first ablative shape enhancing vision of near objects through a central zone of an eye; ablating a corneal surface of a first eye ofthe patient according to the first ablative shape; determining a second ablative shape for a corneal surface, the second ablative shape enhancing vision of near objects through a peripheral zone of an eye; and ablating a corneal surface of a second eye ofthe patient according to the second ablative shape.
- the first ablative shape comprises a central zone having a substantially spherical shape, while in other embodiments the first ablative shape comprises a central zone having a multifocal aspheric surface.
- the first ablative shape may include a small central portion ofthe central zone that remains untreated.
- the central zone ofthe first ablative shape has a diameter scaled to a diameter of a pupil ofthe first eye.
- the central zone ofthe eye according to the first ablative shape has an optical power of between about 0.5 and 4.0 D, more preferably between about 1.0 and 3.0 D, and even more preferably about 1.75 D.
- the first ablative shape includes a peripheral zone shaped to provide for vision of distant objects.
- the peripheral zone in some embodiments extends radially outward from an outer boundary ofthe central zone ofthe first ablative shape.
- the first ablative shape may further include a transition zone extending from an outer boundary ofthe peripheral zone.
- the peripheral zone ofthe second ablative shape extends circumferentially around a center ofthe corneal surface.
- the second ablative shape includes an untreated central zone to provide for vision of distant objects.
- the second ablative shape includes a central zone shaped to improve the patient's ability to view distant objects.
- a laser eye surgery system for treating presbyopia in a patient includes a laser device for emitting a beam of ablative energy and a processor coupled with the laser device to direct the beam of ablative energy to ablate a first ablative shape on a corneal surface of a first eye ofthe patient and a second ablative shape on a corneal surface of a second eye ofthe patient.
- the first ablative shape enhances near vision through a central zone ofthe first eye
- the second ablative shape enhances near vision through a peripheral zone ofthe second eye.
- FIG. 1 is a diagrammatic illustration of two different ablation shapes, each shape for a different eye ofthe same patient, according to one embodiment ofthe present invention.
- FIGS. 2A and 2B are diagrammatic illustrations of two different power profiles resulting from ablation shapes such as those shown in FIG. 1, according to one embodiment ofthe present invention.
- FIG. 3 is a side sectional view of an eye treated to enhance vision of near objects through a central zone ofthe eye, according to one embodiment ofthe present invention.
- FIG. 4 illustrates an ablation profile on a corneal surface for enhancing vision of near objects through a central zone ofthe eye, according to one embodiment ofthe present invention.
- FIG. 5 is a side sectional view of an eye treated to enhance vision of near objects through a peripheral zone ofthe eye, according to one embodiment ofthe present invention.
- FIG. 6 illustrates an ablation profile on a corneal surface for enhancing vision of near objects through a peripheral zone ofthe eye, according to one embodiment ofthe present invention.
- FIG. 7 is a block diagram of an ophthalmic surgery system for incorporating the invention.
- While methods and systems ofthe present invention are described primarily in the context of improving laser eye surgery methods and systems, various embodiments may also be adapted for use in alternative eye treatment procedures and systems such as femtosecond lasers and laser treatment, infrared lasers and laser treatments, radial keratotomy (RK), scleral bands, follow up diagnostic procedures, and the like.
- techniques and systems ofthe present invention may be adapted for use in other eye treatment procedures and systems, such as contact lenses, intra-ocular lenses, radial keratotomy, collagenous comeal tissue thermal remodeling, removable comeal lens structures, glass spectacles and the like.
- the present invention is particularly useful for enhancing laser eye surgical procedures such as photorefiractive keratectomy (PRK), phototherapeutic keratectomy (PTK), laser in situ keratomileusis (LASIK), and the like.
- PRK photorefiractive keratectomy
- PTK phototherapeutic keratectomy
- LASIK laser in situ keratomileusis
- Various embodiments provide enhance presbyopia correction approaches by using improved combinations of ablation shapes for a patient's eyes.
- the techniques ofthe present invention can be readily adapted for use with existing laser systems, including the VISX Excimer laser eye surgery systems commercially available from VISX of Santa Clara, California. By utilizing two different comeal ablation profiles for two different eyes of a patient, the present invention may enhance treatment of presbyopia.
- a first eye of a patient is ablated to have a shape that enhances vision of near objects through a central region (or "central zone") ofthe first eye.
- a number of different ablation shapes and techniques may be used in various embodiments, such as shapes/techniques described in U.S. Patent No. 6,280,435, U.S. Patent No. 6,663,619 and/or U.S. Patent Application Serial No. 10/738,358 (Attorney Docket No. 018158-022220US), all of which are assigned to the assignee ofthe present invention, and all of which are hereby fully incorporated by reference.
- the second eye ofthe patient is ablated to have a shape that enhances vision of near objects through a peripheral region (or "peripheral zone") ofthe second eye.
- Any suitable ablation techniques or shapes may be used, according to various embodiments.
- an ablation technique and shape as described in U.S. Patent Application Serial No. 09/841,674 Publication No. 2002/0156467) may be used.
- techniques of the present invention provide for enhanced treatment of presbyopia.
- the patient will typically view both near and distant objects with both eyes. As the patient's pupils constrict, one eye will predominate for near vision and the other will predominate for distance vision. As the patient's pupils dilate, the predominant near and distance vision eyes will switch.
- the combination ofthe two ablation shapes enhances the patient's ability to view near, far and intermediate objects with an acceptable amount of acuity and without requiring bifocals or monovision systems.
- FIG. 1 illustrates a first ablation profile 110, which may be applied to a first eye of a patient, and a second ablation profile 120, which may be applied to a second eye ofthe same patient.
- the first profile 110 may be used for the patient's left eye and the second profile 120 may be used for the right eye, while in other patients the profiles may be used for the opposite eyes.
- the profiles shown in FIG. 1 are diagrams used solely for illustrative purposes. They are not drawn to scale and do not limit actual ablation profiles used in various embodiments ofthe invention in any way.
- FIG. 1 illustrates ablative shapes 110, 120 along a pupil 103 of each of two eyes of a patient, each pupil 103 having a pupil center 101.
- the hash-marked areas represent tissue removed 112, 122 from a comeal surface by ablation, typically by laser.
- Both ablative shapes 110, 120 include a central zone 102 and a peripheral zone 104.
- the removed tissue 112 creates a shape that enhances near vision through the central zone 102 and distance vision through the peripheral zone 104.
- the removed tissue 122 creates a shape that enhances distance vision through the central zone 102 and near vision through the peripheral zone 104.
- These ablation shapes 110, 120 may be used on the left and right eyes ofthe same patient, so that near and distance vision is enhanced through different portions of each eye.
- FIGS. 2A and 2B two power diagrams 130, 140 illustrate dioptic powers ofthe two ablation shapes in FIG. 1, with a first power diagram 130 of FIG. 2 A corresponding to the first ablation shape 110, and a second power diagram 140 of FIG. 2B corresponding to the second ablation shape 120.
- the first power diagram 130 shows that power 132 increases toward +2 diopters (+2D) from the outer edge ofthe peripheral zone 104 toward the central zone 102 with the first ablative shape 110.
- the second power diagram shows that power 132 decreases from +2 diopters (+2D) from the outer edge ofthe peripheral zone 104 toward the central zone 102 with the second ablative shape 120.
- FIG. 3 a schematic side view of a cornea 200 treated according to one embodiment is illustrated.
- the cornea 200 has an anterior surface that provides most of the refractive power ofthe eye.
- the initial anterior surface 205 ofthe cornea 200 has been reshaped to a desired profile.
- the desired profile includes anterior optical surface 210 and anterior transition surface 215.
- the anterior optical surface 210 has a multifocal aspheric shape that corrects for near vision centrally and far vision peripherally.
- Such a profile is similar to the first ablation profile 110 in FIG. 1.
- the present invention will often be described with reference to the mitigation of presbyopia in combination with refractive hyperopia treatment, the benefits ofthe present invention are not limited to these specific procedures.
- These presbyopia treatment techniques may be used when no other refractive correction (other than the correction, mitigation, and or inhibition of presbyopia) is desired, or the present treatment maybe combined with therapies for one or more of myopia, astigmatism, irregular refractive aberrations, and the like, as well as with hyperopia.
- Still other aspects ofthe present invention including methods and systems which accommodate and adjust for re-epithelization, may find uses in a broad variety of ophthalmic procedures.
- Anterior transition surface 215 is the anterior surface of the cornea that provides a gradual change in shape between anterior optical surface 210 and the portion ofthe cornea retaining the initial anterior surface 205.
- the outer boundary 212 ofthe anterior optical surface preferably extends entirely across, and is ideally substantially coextensive with, the pupil which is bounded by iris 220.
- the light rays passing through anterior transition surface 215 do not contribute to the image formed by anterior optical surface 210. Therefore, anterior transition surface 215 is desirably positioned outside the pupil. This positioning of anterior transition surface 215 causes the light rays passing through anterior transition surface 215 to be substantially occluded by iris 220. This occlusion improves patient vision because the light rays are blocked that do not contribute to image formation, and which would otherwise reduce the contrast ofthe image.
- the optical correction effected by an ablative surgical procedure to the cornea is derived from a change in the anterior comeal surface from an initial anterior surface 205 to post-operative anterior optical surface 210.
- the anterior optical correction is the postoperative anterior optical surface 210 minus the initial anterior surface 205.
- An ablation profile is a change in an exposed surface profile occurring immediately after the tissue removal process. Therefore, the ablation profile is the exposed surface profile immediately after the tissue removal process minus the initial exposed surface profile.
- ablation profile or "ablative shape” can refer either to an ablation-induced change in a surface topography on a surface ofthe cornea, or to the surface topography ofthe cornea after ablation.
- a central add while leaving a central region ofthe optical zone untreated as illustrated in FIG. 4.
- a small untreated zone 500 centered on the optical zone 502 of an ablated cornea has a dimension 504 across the untreated zone.
- the untreated zone 504 is smoothed by covering and healing ofthe cornea and contributes to the formation of a central anterior optical surface that corrects presbyopia.
- FIG. 5 a schematic side view of a cornea 300 treated to achieve peripheral add, according to one embodiment, is shown.
- the cornea 300 has an anterior surface that provides most ofthe refractive power ofthe eye.
- the initial anterior surface 305 ofthe cornea 300 has been reshaped to a desired profile.
- the desired profile includes anterior optical surface 305 that corrects for near-vision peripherally and far- ision centrally.
- anterior optical surface 305 is ablated lateral to pupil, which is bounded by iris 320.
- a central zone 312 ofthe comeal surface 305 is not ablated, thus providing for distance vision through central zone 312.
- central zone 312 maybe ablated to enhance distance vision through central zone 312.
- FIG. 6 schematically shows an ablation shape for providing peripheral add as just described.
- a central zone 600 having a radius of about 5.0 mm, is untreated, while a peripheral zone 610 is ablated to enhance near vision.
- the untreated central zone 600 is then used primarily for distance vision.
- FIG. 7 illustrates a block diagram of an ophthalmic surgery system for incorporating the invention.
- a personal computer (PC) work station 10 is coupled to an embedded computer 21 of a laser surgery unit 20 by means of a first bus connection 11.
- the PC work station 10 comprises a tangible medium 12 and a treatment table 14.
- Tangible medium 12 will typically comprise a memory, magnetic recording media, an optical disk, or the like, and will generally comprise machine readable programming instruction code implementing the method steps described herein.
- the laser treatment table 14 includes a listing of coordinate references of he laser beam during an ablation ofthe cornea.
- the subcomponents of laser surgery unit 20 are known components and preferably comprise the elements ofthe VISX STARTM Excimer Laser Systems, such as the STAR S4TM System, available from VISX, Incorporated of Santa Clara, California.
- the laser surgery system 20 includes a plurality of sensors generally designated with reference numeral 22 which produce feedback signals from the movable mechanical and optical components in the laser optical system, such as the elements driven by an iris motor 23, an image rotator 24, an astigmatism motor 25 and an astigmatism angle motor 26.
- the feedback signals from sensors 22 arc provided via appropriate signal conductors to the embedded computer 21.
- the embedded computer 21 controls the operation ofthe motor drivers generally designated with reference numeral 27 for operating the elements 23-26.
- embedded computer 21 controls the operation ofthe excimer laser 28, which is preferably an argon-fluorine laser with a 193 nanometer wavelength output designed to provide feedback stabilized fluence of 160 mJoules per square centimeter at the cornea ofthe patient's eye 30 via the delivery system optics generally designated with reference numeral 29.
- the excimer laser 28 is preferably an argon-fluorine laser with a 193 nanometer wavelength output designed to provide feedback stabilized fluence of 160 mJoules per square centimeter at the cornea ofthe patient's eye 30 via the delivery system optics generally designated with reference numeral 29.
- other suitable laser systems may be utilized in the present invention including, for example, those manufactured by Alcon, Bausch & Lomb, Wavelight, Nidek, Schwind, Zeiss-Meditec, Lasersight, and the like.
- Other lasers having a suitable wavelength may be used to make an ablative energy for removing a tissue from the eye.
- solid state lasers such as a yttrium aluminum garnet (YAG) laser producing a fifth harmonic of a fundamental wavelength may be used to generate an ablative energy.
- YAG yttrium aluminum garnet
- Other ancillary components ofthe laser surgery system 20 which are not necessary to an understanding ofthe invention, such as a high resolution microscope, a video monitor for the microscope, a patient eye retention system, and an ablation effluent evacuator/filter, as well as the gas delivery system, have been omitted to avoid prolixity.
- the keyboard, display, and conventional PC subsystem components e.g., flexible and hard disk drives, memory boards and the like
- embedded computer 21 maybe constructed with PC work station components and built into laser surgery system 20. hi this case embedded computer 21 may supplant PC workstation 10.
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Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0511244-3A BRPI0511244A (en) | 2004-05-18 | 2005-05-17 | methods for treating presbyopia in a patient and for performing laser eye surgery in a patient for treating presbyopia, and laser surgery system for treating presbyopia in a patient |
CA2567299A CA2567299C (en) | 2004-05-18 | 2005-05-17 | Binocular optical treatment for presbyopia |
MXPA06013328A MXPA06013328A (en) | 2004-05-18 | 2005-05-17 | Binocular optical treatment for presbyopia. |
AU2005245009A AU2005245009B2 (en) | 2004-05-18 | 2005-05-17 | Binocular optical treatment for presbyopia |
JP2007527535A JP5160226B2 (en) | 2004-05-18 | 2005-05-17 | Binocular optical treatment for presbyopia |
EP05754370.4A EP1750633B1 (en) | 2004-05-18 | 2005-05-17 | Binocular optical treatment for presbyopia |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/849,573 | 2004-05-18 | ||
US10/849,573 US20050261752A1 (en) | 2004-05-18 | 2004-05-18 | Binocular optical treatment for presbyopia |
Publications (2)
Publication Number | Publication Date |
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WO2005112844A2 true WO2005112844A2 (en) | 2005-12-01 |
WO2005112844A3 WO2005112844A3 (en) | 2006-11-30 |
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ID=35376237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/US2005/017991 WO2005112844A2 (en) | 2004-05-18 | 2005-05-17 | Binocular optical treatment for presbyopia |
Country Status (8)
Country | Link |
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US (2) | US20050261752A1 (en) |
EP (1) | EP1750633B1 (en) |
JP (1) | JP5160226B2 (en) |
AU (1) | AU2005245009B2 (en) |
BR (1) | BRPI0511244A (en) |
CA (1) | CA2567299C (en) |
MX (1) | MXPA06013328A (en) |
WO (1) | WO2005112844A2 (en) |
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CA2720573C (en) * | 2008-04-04 | 2019-08-13 | Revision Optics, Inc. | Corneal inlay design and methods of correcting vision |
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US8529558B2 (en) | 2008-04-22 | 2013-09-10 | Amo Development Llc. | High-order optical correction during corneal laser surgery |
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Also Published As
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EP1750633A2 (en) | 2007-02-14 |
BRPI0511244A (en) | 2007-11-27 |
WO2005112844A3 (en) | 2006-11-30 |
CA2567299A1 (en) | 2005-12-01 |
US20090234336A1 (en) | 2009-09-17 |
EP1750633B1 (en) | 2015-02-25 |
MXPA06013328A (en) | 2007-05-04 |
JP5160226B2 (en) | 2013-03-13 |
US20050261752A1 (en) | 2005-11-24 |
AU2005245009B2 (en) | 2010-09-09 |
AU2005245009A1 (en) | 2005-12-01 |
JP2007537845A (en) | 2007-12-27 |
EP1750633A4 (en) | 2010-04-07 |
CA2567299C (en) | 2013-01-29 |
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