WO2005112830A1 - C-shaped heart valve prostheses - Google Patents
C-shaped heart valve prostheses Download PDFInfo
- Publication number
- WO2005112830A1 WO2005112830A1 PCT/US2005/016676 US2005016676W WO2005112830A1 WO 2005112830 A1 WO2005112830 A1 WO 2005112830A1 US 2005016676 W US2005016676 W US 2005016676W WO 2005112830 A1 WO2005112830 A1 WO 2005112830A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- prosthesis
- plan
- view plane
- valve
- view
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
- A61F2/2448—D-shaped rings
Definitions
- Annuloplasty rings are well known as prostheses for heart valves that are not functioning properly. See, for example, Alfieri et al . U.S. patent application publication US 2002/0173844 Al and Boiling et al . U.S. patent application publication US 2003/0093148 Al . Prostheses that are less than complete rings are also known for this purpose. See, for example, Carpentier U.S. patent 3,656,185. The less-than-complete rings that are known tend to be flat. This may not be the best shape for providing the most effective and beneficial prosthesis. This invention aims at providing less-than-complete-ring prostheses having more effective shapes and other beneficial features. Summary of the Invention
- a heart valve prosthesis in accordance with the invention is generally C-shaped in plan view. Points at the top and bottom of the C lie in a plan view plane. The back of the C rises above the plan view plane between the top and bottom points. Free end portions of the C (remote from the back, beyond the top and bottom points) may also rise above the plan view plane.
- the prosthesis is accordingly preferably saddle-shaped.
- the back of the C may also have an indentation or pinch that extends inwardly toward the open side of the C.
- the top and bottom of the C are respectively adjacent the commissures of the valve, and the back of the C is adjacent the posterior section of the valve.
- the prosthesis may be rigid or semirigid.
- FIG. 1 is a simplified plan view of an illustrative embodiment of a heart valve prosthesis in accordance with the invention.
- FIG. 2 is a simplified elevational view taken along the line 2-2 in FIG. 1.
- FIG. 3 is another simplified elevational view taken along the line 3-3 in FIG. 2.
- FIG. 4 is another view similar to FIG. 1 with some dimensional references added.
- FIG. 5 is similar to FIG. 1, but shows another illustrative embodiment in accordance with the invention.
- FIG. 6 is a simplified elevational view taken along the line 6-6 in FIG. 5.
- FIGS. 1-4 An illustrative embodiment of a heart valve prosthesis 10 in accordance with the invention is shown in FIGS. 1-4.
- This illustrative embodiment is intended for use as a mitral valve prosthesis.
- Prosthesis 10 will be implanted part way around a patient's mitral valve, with the posterior portion of the valve on the left as viewed in FIG. 1.
- Prosthesis 10 is generally C shaped in plan view (see FIGS. 1 and 4) .
- An upper medial point 12 and a lower medial point 14 of the C may be thought of as lying in a plan view plane of the prosthesis.
- This plan view plane is indicated by the (imaginary) line 20 in FIG. 2.
- Line 22 (also imaginary) in FIG. 3 also lies in this plane.
- Points 12 and 14 are referred to as medial, not because they are at the midpoint (s) of any structure, but only because they are interior to the length of the C-shaped structure (i.e., not at the free end points of the C) .
- the back 30 of the C is deflected upwardly out of the above-mentioned plan view plane (defined by lines 20 and 22 as described above) .
- This upward deflection is clearly visible in FIGS. 2 and 3. It preferably starts at each of points 12 and 14, and also preferably goes smoothly up to a maximum upward deflection at a midpoint 32 on the back of the C between points 12 and 14.
- prosthesis 10 is preferably smooth at all points along the length of the prosthesis.
- the deflections described as upward in this specification will also be generally upward after prosthesis 10 has been implanted in a patient as a mitral valve prosthesis and the patient is standing upright .
- the free end portions 42 and 44 of prosthesis 10 are also preferably deflected upwardly out of the above-mentioned plan view plane (defined by lines 20 and 22 as described above) .
- Free end portion 42 is remote from back 30 beyond point 12 (i.e., free end portion 42 is on the opposite or far side of point 12 from back 30) .
- Free end portion 44 is similarly remote from back 30 beyond point 14.
- Points 12 and 14 are preferably at endpoints of a greatest height (or width) dimension 50 of prosthesis 10 (see FIG. 4) .
- dimension 50 may sometimes be referred to as the commissure-to- commissure ("CC") dimension or the commissure width ("CW") dimension of the prosthesis.
- FIG. 4 also shows the anterior-posterior ("AP") dimension 52 of prosthesis 10.
- the maximum upward deflection of back 30 is dimension 60 in FIGS. 2 and 3.
- Dimension 60 is preferably in the range from about 5% to about 25% of dimension 50.
- dimension 60 may be in the range from about 3 mm to about 8 mm.
- the back 30 of the prosthesis may have an indentation or pinch 34 to reduce the AP to CC ratio (i.e., the ratio of dimension 52' to dimension 50) .
- Pinch 34 is located at or near the center of back 30 of prosthesis 10'. Pinch 34 is inward, toward the open side of the C
- prosthesis 10' can be similar to prosthesis 10.
- a prosthesis 10 or 10 ' in accordance with this invention can be used for mitral valve repair by supporting the posterior section of the mitral annulus .
- the prosthesis is implanted, using techniques that can be conventional, with back 30 adjacent that posterior valve annulus section.
- the prosthesis aids in returning the posterior section of the mitral valve back to its natural saddle shape (commissures low and posterior and anterior sections arching upwardly between the commissures) , and also provides support for a valve with functional mitral regurgitation.
- Prosthesis 10 or 10' is preferably fully rigid or at least semi-rigid to retain its saddle shape.
- the saddle shape preferably has a 5% to 25% height-to-commissure-width ratio, or an absolute height from lowest point of the prosthesis to highest point of 3 mm to 8 mm.
- the core material of the prosthesis can be made from a polymer such as ultra-high-molecular-weight polyethylene, polyurethane, ABS, or the like that will allow it to flex to some degree but that will also hold the saddle shape.
- Shape-memory alloys such as Nitinol can also be used to create such a semi-rigid prosthesis that flexes.
- a three-dimensional, semi-rigid prosthesis not only flexes in the X and Y directions (see (FIG. 1) , but also in the Z direction (see (FIG. 1) , but also in the Z direction (see
- FIG. 2 These three axes of flexibility will allow the ring to conform to the dynamic movement of the mitral valve region of the heart .
- Flexing of the prosthesis in the Z direction is accomplished to a large degree by wing flexing (indicated by arrows 70 in FIG. 2) of the prosthesis.
- the amount of flexing depends on the cross-sectional shape and elastic properties of the material employed for the prosthesis core. However, the amount of flexing employed should not allow the prosthesis to lose its saddle shape, unless there is an intentional purpose to do so. For example, the diameter of a wire, tube, or rod of shape- memory alloy used for the core will influence the amount of flex or movement that occurs after the material is formed into the shape desired.
- a rigid prosthesis 10 or 10 ' can be created using stronger material such as elgiloy, titanium, stainless steel, cobalt chrome, or ceramic. However, such a rigid prosthesis will not move with the heart in the same way as a semi-rigid prosthesis will.
- Prosthesis 10 can have an anterior-posterior ("AP") to commissure-commissure (“CC”) ratio in the range from about 0.75 to about 0.4 to treat most mitral valve diseases. (Again, dimensions 50 and 52 in FIG. 4 are the CC and AP dimensions, respectively.) To get the required amount of flexing in all three axes (X, Y and Z) , the AP to CC ratio can vary within the 0.75 to 0.4 range .
- the illustrative embodiments shown herein are at least substantially symmetrical about a plane that (1) is perpendicular to the plan view plane, (2) passes through the high point 32 of back 30, and (3) passes midway between the free ends of the C.
- This plane of symmetry can also be described as a plane perpendicular to a line between points 12 and 14, and which plane is midway between points 12 and 14.
- symmetry may not be desired in all cases, and it will be understood that various kinds of asymmetry can be employed to meet various needs .
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007513367A JP2007537006A (en) | 2004-05-14 | 2005-05-12 | C heart valve prosthesis |
EP05750081A EP1761210A1 (en) | 2004-05-14 | 2005-05-12 | C-shaped heart valve prostheses |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57108704P | 2004-05-14 | 2004-05-14 | |
US60/571,087 | 2004-05-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005112830A1 true WO2005112830A1 (en) | 2005-12-01 |
Family
ID=34969839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/016676 WO2005112830A1 (en) | 2004-05-14 | 2005-05-12 | C-shaped heart valve prostheses |
Country Status (4)
Country | Link |
---|---|
US (1) | US20050256568A1 (en) |
EP (1) | EP1761210A1 (en) |
JP (1) | JP2007537006A (en) |
WO (1) | WO2005112830A1 (en) |
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WO2007143077A3 (en) * | 2006-06-02 | 2008-04-03 | Medtronic Inc | Annuloplasty ring and method |
WO2008094469A2 (en) * | 2007-01-26 | 2008-08-07 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
WO2008134723A1 (en) | 2007-05-01 | 2008-11-06 | Edwards Lifesciences Corporation | Inwardly-bowed tricuspid annuloplasty ring |
WO2009139776A1 (en) * | 2008-05-13 | 2009-11-19 | Edwards Lifesciences Corporation | Physiologically harmonized tricuspid annuloplasty ring |
US8197538B2 (en) | 2006-06-02 | 2012-06-12 | Medtronic, Inc. | Annuloplasty prosthesis with in vivo shape identification and related methods of use |
US9339381B2 (en) | 2005-08-25 | 2016-05-17 | Edwards Lifesciences Corporation | Four-leaflet stented mitral heart valve |
US9801718B2 (en) | 2007-01-26 | 2017-10-31 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
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US6332893B1 (en) | 1997-12-17 | 2001-12-25 | Myocor, Inc. | Valve to myocardium tension members device and method |
US6723038B1 (en) | 2000-10-06 | 2004-04-20 | Myocor, Inc. | Methods and devices for improving mitral valve function |
US6786924B2 (en) * | 2001-03-15 | 2004-09-07 | Medtronic, Inc. | Annuloplasty band and method |
US6955689B2 (en) * | 2001-03-15 | 2005-10-18 | Medtronic, Inc. | Annuloplasty band and method |
ITMI20011012A1 (en) | 2001-05-17 | 2002-11-17 | Ottavio Alfieri | ANNULAR PROSTHESIS FOR MITRAL VALVE |
US7935145B2 (en) | 2001-05-17 | 2011-05-03 | Edwards Lifesciences Corporation | Annuloplasty ring for ischemic mitral valve insuffuciency |
US7367991B2 (en) * | 2001-08-28 | 2008-05-06 | Edwards Lifesciences Corporation | Conformal tricuspid annuloplasty ring and template |
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US6805710B2 (en) * | 2001-11-13 | 2004-10-19 | Edwards Lifesciences Corporation | Mitral valve annuloplasty ring for molding left ventricle geometry |
US6764510B2 (en) | 2002-01-09 | 2004-07-20 | Myocor, Inc. | Devices and methods for heart valve treatment |
US7608103B2 (en) * | 2002-07-08 | 2009-10-27 | Edwards Lifesciences Corporation | Mitral valve annuloplasty ring having a posterior bow |
US7112219B2 (en) | 2002-11-12 | 2006-09-26 | Myocor, Inc. | Devices and methods for heart valve treatment |
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US7842085B2 (en) * | 2005-03-23 | 2010-11-30 | Vaso Adzich | Annuloplasty ring and holder combination |
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US10456259B2 (en) | 2008-04-16 | 2019-10-29 | Heart Repair Technologies, Inc. | Transvalvular intraannular band for mitral valve repair |
US11083579B2 (en) | 2008-04-16 | 2021-08-10 | Heart Repair Technologies, Inc. | Transvalvular intraanular band and chordae cutting for ischemic and dilated cardiomyopathy |
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US9314335B2 (en) | 2008-09-19 | 2016-04-19 | Edwards Lifesciences Corporation | Prosthetic heart valve configured to receive a percutaneous prosthetic heart valve implantation |
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JP2020501842A (en) | 2016-12-22 | 2020-01-23 | ハート・リペアー・テクノロジーズ・インコーポレーテッド | Percutaneous delivery system for securing an implant to a heart valve annulus |
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- 2005-05-12 EP EP05750081A patent/EP1761210A1/en not_active Withdrawn
- 2005-05-12 WO PCT/US2005/016676 patent/WO2005112830A1/en active Application Filing
- 2005-05-12 JP JP2007513367A patent/JP2007537006A/en active Pending
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Cited By (15)
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US9339381B2 (en) | 2005-08-25 | 2016-05-17 | Edwards Lifesciences Corporation | Four-leaflet stented mitral heart valve |
US8197538B2 (en) | 2006-06-02 | 2012-06-12 | Medtronic, Inc. | Annuloplasty prosthesis with in vivo shape identification and related methods of use |
WO2007143077A3 (en) * | 2006-06-02 | 2008-04-03 | Medtronic Inc | Annuloplasty ring and method |
US9283073B2 (en) | 2006-06-02 | 2016-03-15 | Medtronic, Inc. | Annuloplasty ring and method |
US10130473B2 (en) | 2007-01-26 | 2018-11-20 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
WO2008094469A3 (en) * | 2007-01-26 | 2008-11-13 | Medtronic Inc | Annuloplasty device for tricuspid valve repair |
EP3488822A1 (en) * | 2007-01-26 | 2019-05-29 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
US8535374B2 (en) | 2007-01-26 | 2013-09-17 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
WO2008094469A2 (en) * | 2007-01-26 | 2008-08-07 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
US9801718B2 (en) | 2007-01-26 | 2017-10-31 | Medtronic, Inc. | Annuloplasty device for tricuspid valve repair |
WO2008134723A1 (en) | 2007-05-01 | 2008-11-06 | Edwards Lifesciences Corporation | Inwardly-bowed tricuspid annuloplasty ring |
CN102088930A (en) * | 2008-05-13 | 2011-06-08 | 爱德华兹生命科学公司 | Physiologically harmonized tricuspid annuloplasty ring |
US9937041B2 (en) | 2008-05-13 | 2018-04-10 | Edwards Lifesciences Corporation | Physiologically harmonized tricuspid annuloplasty ring |
WO2009139776A1 (en) * | 2008-05-13 | 2009-11-19 | Edwards Lifesciences Corporation | Physiologically harmonized tricuspid annuloplasty ring |
US11903830B2 (en) | 2008-05-13 | 2024-02-20 | Edwards Lifesciences Corporation | Physiologically harmonized repair of tricuspid valve |
Also Published As
Publication number | Publication date |
---|---|
EP1761210A1 (en) | 2007-03-14 |
JP2007537006A (en) | 2007-12-20 |
US20050256568A1 (en) | 2005-11-17 |
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