WO2005100959A1 - Inspection system for blister packages - Google Patents
Inspection system for blister packages Download PDFInfo
- Publication number
- WO2005100959A1 WO2005100959A1 PCT/US2005/009510 US2005009510W WO2005100959A1 WO 2005100959 A1 WO2005100959 A1 WO 2005100959A1 US 2005009510 W US2005009510 W US 2005009510W WO 2005100959 A1 WO2005100959 A1 WO 2005100959A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- blister package
- imaged
- fill level
- predetermined
- grey level
- Prior art date
Links
- 238000007689 inspection Methods 0.000 title claims abstract description 43
- 238000003384 imaging method Methods 0.000 claims abstract 5
- 238000000034 method Methods 0.000 claims description 14
- 238000007789 sealing Methods 0.000 description 10
- 239000011888 foil Substances 0.000 description 5
- 239000004743 Polypropylene Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000004922 lacquer Substances 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 238000011109 contamination Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
- B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
- B07C5/34—Sorting according to other particular properties
- B07C5/342—Sorting according to other particular properties according to optical properties, e.g. colour
- B07C5/3422—Sorting according to other particular properties according to optical properties, e.g. colour using video scanning devices, e.g. TV-cameras
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B25/00—Packaging other articles presenting special problems
- B65B25/008—Packaging other articles presenting special problems packaging of contact lenses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
- G01N21/9054—Inspection of sealing surface and container finish
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/95—Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
- G01N21/9508—Capsules; Tablets
Definitions
- the present invention relates to inspection systems in a production line. More particularly, the present invention relates to an inspection system for inspecting the seal area and/or solution volume of a blister package containing an ophthalmic lens in solution.
- Ophthalmic lenses such as contact lenses are commonly packaged in small containers referred to as blister packages comprising a disposable plastic container having a well for containing a single lens in a quantity of storage solution (e.g., saline).
- a foil lidstock is applied to the blister package and sealed thereto, usually around the perimeter of the well containing the lens and solution.
- the foil lidstock may comprise a laminate, for example, a first polypropylene layer which is laid against the blister followed by a foil layer on which a paint layer may be applied for graphic application followed by a top lacquer layer.
- Sealing the lidstock to the blister package may be carried out by the application of heat which seals the poylpropylene layer to the plastic blister.
- the sealing process is carried out in an automated fashion such that many blister packages may be sealed very quickly. Although automation increases productivity of the production line, errors may happen during the sealing process which may go undetected. Sealing errors may include, for example, bubbles, voids, particulate matter, and oversealing.
- the present invention provides an inspection system which is operable to detect errors in the seal area of a lidstock applied to a blister package.
- the inspection system includes an image pick-up device (e.g., a camera) directed toward the seal area of a blister package.
- the seal area is typically the area surrounding the recessed well which houses the lens and storage solution although it may also include a larger flange area surrounding the well.
- the seal around the perimeter of the well typically referred to as a "racetrack" in the art, must be a complete seal or else the lens may become contaminated and solution may leak from the blister package which must then be discarded.
- the inspection system applies a pattern to the racetrack, for example, small square or rectangle boxes placed in succession around the complete racetrack.
- a software utility connected to the image pick-up device checks the pattern for a predetermined amount or range of grey level within the boxes. A difference from a threshold grey level is treated as an error. This is because a good seal will have a measurable grey level value or range caused by the correct application of heat, pressure and time to the two materials being bonded together (i.e., the lidstock and the blister racetrack). If the detected grey level is different than the threshold value or range, the software utility then calculates the size of the detected error. If the size is outside the acceptable value or range, that blister is targeted for disposal.
- an inspection system is provided for inspecting the volume (fill level) of storage solution in a sealed blister package.
- the vision system includes an image pick-up device (e.g., a camera) which is operable to detect the solution level within a blister package.
- the blister package may be presented vertically to the image device. If the detected solution level falls outside a predetermined accepted amount or range, that blister package is targeted for disposal.
- the seal inspection system is integrated with the volume inspection system.
- Figure 1 is a perspective view of a representative blister package showing the cover peeled partly off;
- Figure 2 is a cross-sectional view of the blister package as taken generally along the line 2-2 of Fig. 1 except the cover is sealed to the blister package;
- Figure 3 is a bottom plan view of the blister package;
- Figure 4 is an enlarged cross-section view of the cover showing the individual layers thereof;
- Figure 5 is a schematic view of the inspection system set-up of the present invention;
- Figure 6 is a bottom plan view of a blister package showing a consecutive array of white ROIs on part of the seal area of a blister package undergoing inspection;
- Figure 7 is the view of Fig. 6 showing one type of seal error detected by the inspection system;
- Figure 8 is the view of Fig. 7 showing yet another type of possible seal error;
- Figure 9 is a bottom plan view of a blister package showing inspection of the volume fill level of the package; and
- Figure 10 is the view of Fig. 9 showing a different fill level.
- Blister 10 used for packaging a hydrophilic contact lens 12.
- Blister 10 is made of a disposable plastic (e.g.,polypropylene) and includes a recessed well 14 wherein lens 12 is placed with a quantity of storage solution 13 (e.g., saline).
- a cover 16 is sealed about the well 14.
- Cover 16 is typically a foil laminate having a first base layer which will bond to the blister package upon application of heat and pressure.
- the first, base layer 16a may be polypropylene, for example, followed by a foil layer 16b and a protective lacquer top layer 16c.
- Cover 16 is sealed at least about the perimeter or "racetrack" 18 of the well 14.
- Racetrack 18 may be flush or raised relative to the flange area 19 surrounding the racetrack 18.
- Cover 16 may further include an unsealed gripping portion 16d to enable a user to easily grasp and peel cover 16 from blister 10 to access the lens 12 therein.
- the inspection system station 20 of the invention is shown schematically and includes an image pick-up device (e.g., a DSL5000 camera) 22 having a lens 24 (e.g., a 35mm lens) directed at a blister package 10 to be inspected.
- a low angle light ring 26 is positioned between blister package 10 and image pick-up device 22.
- Blister package 10 has previously had a lens 12 and storage solution 13 deposited in well 14 thereof and a cover 20 sealed thereto about racetrack 18.
- the sealing station may comprise a heat sealing station which applies heat and pressure to the cover at the location of the racetrack 18, thereby sealing the well 14 and its contents.
- the blister packages Prior to shipping to the consumer, the blister packages will undergo sterilization to ensure the lens is sterilized for safe application to the user's eye. It is therefore apparent that the sealing process must ensure a seal that will not compromise the sterility of the lens in the blister package.
- inspection station 20 is provided for inspecting the seal area (racetrack) 18 of the blister package. Should the inspection indicate problems with the seal, the blister is targeted for disposal.
- the inspection station image pick-up device 22 includes means for projecting ROIs (regions of interest) onto racetrack area 18 of the sealed blister 10. The ROIs labled 28 in Fig.
- the image pick-up device 22 images the blister 10 and racetrack 18 and connects to a computer 30 having inspection software which analyzes the image picked up by image pick-up device 22.
- Suitable inspection software and harware for use with the present invention includes Inspection Builder 3.1 by PPT Vision System.
- Inspection Builder 3.1 by PPT Vision System To get a baseline reading, a seal known to be good is either directly input or measured by image pick-up device 22 and stored in computer 30. The image pixels are analyzed for their grey level (contrast) and this becomes the accepted baseline number.
- the image pick-up device 22 Upon receiving a blister package for inspection, the image pick-up device 22 images the blister racetrack 18 and the software utility examines the ROIs to determine their grey level. This reading is compared to the baseline number in the computer and if it is within an acceptable deviation range, the blister package is passed for seal inspection. If instead a grey level is detected outside the acceptable deviation range, the software utility next examines the size of the area outside the acceptable deviation range. If the area is of a size which is not acceptable, the blister package is targeted for disposal. If instead the size is deemed within acceptable parameters, the blister package is passed for seal inspection. It is noted that the second analysis step wherein the area size is calculated and compared to an acceptable value previously input into the computer may be seamlessly integrated into the step of grey level analysis by the computer.
- the second analysis may also be eliminated if desired should the grey level analysis be determined sufficient to determine failed blister packages.
- the blister package may be oriented vertically as shown in Fig. 5 during inspection. The bottom of well 14 is directed toward the image pick-up device. Since the blister package is translucent, the image pick-up device can see through the package to racetrack 18. The heat sealing process causes a certain grey level to appear at the racetrack 18 where the cover 20 has adhered to the blister racetrack 18. This grey level contrasts with the grey level appearing at unsealed areas of the cover 20 (i.e., areas both inside and outside racetrack 18). A good seal will have a certain grey level all around the racetrack 18. Measuring this grey level thus enables the system to compare each blister undergoing inspection to the known acceptable grey level.
- FIG. 7 shows a representative blister package 10 undergoing inspection where a seal error in the form of a seal void is indicated at reference numeral 30. This void in the seal area would likely cause leakage of the storage solution from well 14 and contaminate the lens 12 therein. Inspection system 20 will read this area as a difference in acceptable grey level and target this blister package for disposal. The system may either sound a bell to alert a worker for removal of the failed package or the system may send a signal ordering automated machinery to pull the blister form the production line.
- Figure 8 shows another type of seal error in the form of air bubbles 32 captured between cover 20 and racetrack 18.
- a second analysis step may be performed wherein the area size of the grey level detected to be outside acceptable parameters is calculated and compared to an acceptable area value previously input into the computer.
- the fill level (volume) of storage solution 13 may also be inspected by inspection system 20.
- the image pick-up device 22 reads the contrast difference at the fill line FL which is indicative of the solution fill level. If the fill level is detected to be below the threshold level, that blister is target for disposal.
- the volume inspection is done together with the seal inspection.
- the blister packages may be presented to the inspection station 20 in automated succession and may be handled by a conveyor and/or a fixturing device which presents the blister package at the correct orientation to the image pick-up device 22.
- a fixturing device which presents the blister package at the correct orientation to the image pick-up device 22.
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Multimedia (AREA)
- Mechanical Engineering (AREA)
- Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
- Examining Or Testing Airtightness (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05729079A EP1733212A1 (en) | 2004-03-31 | 2005-03-22 | Inspection system for blister packages |
JP2007506236A JP2007530975A (en) | 2004-03-31 | 2005-03-22 | Inspection system for blister packaging |
CA002561040A CA2561040A1 (en) | 2004-03-31 | 2005-03-22 | Inspection system for blister packages |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/813,860 | 2004-03-31 | ||
US10/813,860 US20050226488A1 (en) | 2004-03-31 | 2004-03-31 | Inspection system for blister packages |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005100959A1 true WO2005100959A1 (en) | 2005-10-27 |
Family
ID=34963436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/009510 WO2005100959A1 (en) | 2004-03-31 | 2005-03-22 | Inspection system for blister packages |
Country Status (7)
Country | Link |
---|---|
US (1) | US20050226488A1 (en) |
EP (1) | EP1733212A1 (en) |
JP (1) | JP2007530975A (en) |
CN (1) | CN1934439A (en) |
CA (1) | CA2561040A1 (en) |
TW (1) | TW200600770A (en) |
WO (1) | WO2005100959A1 (en) |
Families Citing this family (16)
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---|---|---|---|---|
US20090113851A1 (en) * | 2007-10-31 | 2009-05-07 | Carr Stephen N | Packaging seal plate having a shaped face |
US20090145086A1 (en) * | 2007-12-11 | 2009-06-11 | Reynolds Ger M | Method for treating ophthalmic lenses |
US8929641B2 (en) * | 2009-03-17 | 2015-01-06 | Aesynt Incorporated | System and method for determining the orientation of a unit dose package |
CN102556437A (en) * | 2010-12-29 | 2012-07-11 | 吴士敏 | Off-line full-automatic bubble cap packaging quality detection system and method thereof |
SG189572A1 (en) * | 2011-10-18 | 2013-05-31 | Menicon Singapore Pte Ltd | Systems and methods for multi-stage sealing of contact lens packaging |
US9470638B2 (en) * | 2012-02-27 | 2016-10-18 | The Procter & Gamble Company | Apparatus and method for detecting leakage from a composition-containing pouch |
JP5526183B2 (en) * | 2012-04-25 | 2014-06-18 | Ckd株式会社 | Inspection device and PTP packaging machine |
CN102700773A (en) * | 2012-06-26 | 2012-10-03 | 上海秉拓机械设备有限公司 | Whole detection machine for rear sections of bubble caps |
US20180134475A1 (en) * | 2012-10-18 | 2018-05-17 | Menicon Singapore Pte Ltd. | Systems and Methods for Multi-Stage Sealing of Contact Lens Packaging |
EP2935016B1 (en) | 2012-12-21 | 2016-09-28 | Novartis AG | Contact lens package |
JP6504053B2 (en) * | 2013-07-19 | 2019-04-24 | ソニー株式会社 | Signal processing apparatus, opening detection module, program, opening detection method and article packaging material |
JP6197542B2 (en) * | 2013-09-30 | 2017-09-20 | 日本電気株式会社 | Appearance inspection apparatus, appearance inspection method, and program |
SG10201501672PA (en) * | 2015-03-05 | 2016-10-28 | Emage Vision Pte Ltd | Inspection of sealing quality in blister packages |
US10293963B2 (en) * | 2016-01-29 | 2019-05-21 | Carefusion Germany 326 Gmbh | Filling station and method for filling a transport tray |
US10269109B2 (en) * | 2016-07-22 | 2019-04-23 | Orora Packaging Solutions | Label inspection and rejection system and method for use thereof |
KR20230019052A (en) * | 2021-07-30 | 2023-02-07 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | Quality control for sealed lens packages |
Citations (8)
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US4245243A (en) * | 1976-08-25 | 1981-01-13 | Kloeckner-Werke Ag | System for registering and sorting out not properly filled deep-drawn packages in a packaging machine |
DE3622112A1 (en) * | 1986-07-02 | 1988-01-07 | Hoechst Ag | Method for monitoring the fillings of sealed tablet packs |
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2004
- 2004-03-31 US US10/813,860 patent/US20050226488A1/en not_active Abandoned
-
2005
- 2005-03-22 JP JP2007506236A patent/JP2007530975A/en not_active Withdrawn
- 2005-03-22 EP EP05729079A patent/EP1733212A1/en not_active Withdrawn
- 2005-03-22 WO PCT/US2005/009510 patent/WO2005100959A1/en not_active Application Discontinuation
- 2005-03-22 CA CA002561040A patent/CA2561040A1/en not_active Abandoned
- 2005-03-22 CN CNA2005800091029A patent/CN1934439A/en active Pending
- 2005-03-30 TW TW094110080A patent/TW200600770A/en unknown
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Publication number | Priority date | Publication date | Assignee | Title |
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US4245243A (en) * | 1976-08-25 | 1981-01-13 | Kloeckner-Werke Ag | System for registering and sorting out not properly filled deep-drawn packages in a packaging machine |
DE3622112A1 (en) * | 1986-07-02 | 1988-01-07 | Hoechst Ag | Method for monitoring the fillings of sealed tablet packs |
US5363968A (en) * | 1991-08-23 | 1994-11-15 | Pfizer Inc. | Automatic blister inspection system |
EP1020381A2 (en) * | 1994-06-10 | 2000-07-19 | JOHNSON & JOHNSON VISION PRODUCTS, INC. | Automated apparatus and method for preparing contact lenses for inspection and packaging |
EP0741078A2 (en) * | 1995-05-01 | 1996-11-06 | JOHNSON & JOHNSON VISION PRODUCTS, INC. | Packaging arrangement |
US20010009561A1 (en) * | 1999-12-03 | 2001-07-26 | Roger Biel | Method and apparatus for detecting mouldings in a package |
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US20020077771A1 (en) * | 2000-09-27 | 2002-06-20 | Richard Mertens | Method for checking the content of pockets in a blister package |
Also Published As
Publication number | Publication date |
---|---|
US20050226488A1 (en) | 2005-10-13 |
CA2561040A1 (en) | 2005-10-27 |
JP2007530975A (en) | 2007-11-01 |
EP1733212A1 (en) | 2006-12-20 |
TW200600770A (en) | 2006-01-01 |
CN1934439A (en) | 2007-03-21 |
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