WO2005097051A2 - Disulfide dyes, composition comprising them and method of dyeing hair - Google Patents
Disulfide dyes, composition comprising them and method of dyeing hair Download PDFInfo
- Publication number
- WO2005097051A2 WO2005097051A2 PCT/EP2005/051412 EP2005051412W WO2005097051A2 WO 2005097051 A2 WO2005097051 A2 WO 2005097051A2 EP 2005051412 W EP2005051412 W EP 2005051412W WO 2005097051 A2 WO2005097051 A2 WO 2005097051A2
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- WIPO (PCT)
- Prior art keywords
- formula
- solution
- alkyl
- independently
- hair
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 142
- 239000000975 dye Substances 0.000 title claims abstract description 131
- 238000000034 method Methods 0.000 title claims abstract description 66
- 210000004209 hair Anatomy 0.000 title claims description 204
- 238000004043 dyeing Methods 0.000 title claims description 60
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims abstract description 164
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 41
- 239000001257 hydrogen Substances 0.000 claims abstract description 41
- 239000000835 fiber Substances 0.000 claims abstract description 34
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 33
- 108090000790 Enzymes Proteins 0.000 claims abstract description 9
- 102000004190 Enzymes Human genes 0.000 claims abstract description 9
- 125000002950 monocyclic group Chemical group 0.000 claims abstract description 6
- 125000003367 polycyclic group Chemical group 0.000 claims abstract description 5
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 5
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 5
- -1 cationic radical Chemical class 0.000 claims description 81
- 150000003254 radicals Chemical class 0.000 claims description 54
- 125000002091 cationic group Chemical group 0.000 claims description 28
- 239000002253 acid Substances 0.000 claims description 23
- 102000011782 Keratins Human genes 0.000 claims description 19
- 108010076876 Keratins Proteins 0.000 claims description 19
- 125000000217 alkyl group Chemical group 0.000 claims description 18
- 239000003795 chemical substances by application Substances 0.000 claims description 18
- 239000000982 direct dye Substances 0.000 claims description 17
- 239000007800 oxidant agent Substances 0.000 claims description 16
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 claims description 15
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 12
- 230000009467 reduction Effects 0.000 claims description 12
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims description 12
- 150000002391 heterocyclic compounds Chemical class 0.000 claims description 11
- PMNLUUOXGOOLSP-UHFFFAOYSA-N 2-mercaptopropanoic acid Chemical compound CC(S)C(O)=O PMNLUUOXGOOLSP-UHFFFAOYSA-N 0.000 claims description 10
- 229910052736 halogen Inorganic materials 0.000 claims description 10
- 150000002367 halogens Chemical class 0.000 claims description 10
- 150000003839 salts Chemical class 0.000 claims description 10
- 125000003342 alkenyl group Chemical group 0.000 claims description 9
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 9
- 150000002431 hydrogen Chemical class 0.000 claims description 8
- 125000006296 sulfonyl amino group Chemical group [H]N(*)S(*)(=O)=O 0.000 claims description 8
- 150000001450 anions Chemical class 0.000 claims description 7
- 150000001491 aromatic compounds Chemical class 0.000 claims description 7
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims description 6
- 125000000129 anionic group Chemical group 0.000 claims description 6
- 125000003118 aryl group Chemical group 0.000 claims description 6
- 125000005842 heteroatom Chemical group 0.000 claims description 6
- 229920006395 saturated elastomer Polymers 0.000 claims description 6
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- DZVCFNFOPIZQKX-LTHRDKTGSA-M merocyanine Chemical compound [Na+].O=C1N(CCCC)C(=O)N(CCCC)C(=O)C1=C\C=C\C=C/1N(CCCS([O-])(=O)=O)C2=CC=CC=C2O\1 DZVCFNFOPIZQKX-LTHRDKTGSA-M 0.000 claims description 4
- 150000002825 nitriles Chemical class 0.000 claims description 4
- 125000005504 styryl group Chemical group 0.000 claims description 4
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 claims description 3
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims description 3
- 125000001072 heteroaryl group Chemical group 0.000 claims description 3
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 claims description 3
- 230000007935 neutral effect Effects 0.000 claims description 3
- 125000004999 nitroaryl group Chemical group 0.000 claims description 3
- 125000001424 substituent group Chemical group 0.000 claims description 3
- VEPOHXYIFQMVHW-XOZOLZJESA-N 2,3-dihydroxybutanedioic acid (2S,3S)-3,4-dimethyl-2-phenylmorpholine Chemical compound OC(C(O)C(O)=O)C(O)=O.C[C@H]1[C@@H](OCCN1C)c1ccccc1 VEPOHXYIFQMVHW-XOZOLZJESA-N 0.000 claims description 2
- BCHZICNRHXRCHY-UHFFFAOYSA-N 2h-oxazine Chemical compound N1OC=CC=C1 BCHZICNRHXRCHY-UHFFFAOYSA-N 0.000 claims description 2
- PQJUJGAVDBINPI-UHFFFAOYSA-N 9H-thioxanthene Chemical compound C1=CC=C2CC3=CC=CC=C3SC2=C1 PQJUJGAVDBINPI-UHFFFAOYSA-N 0.000 claims description 2
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 claims description 2
- PQUCIEFHOVEZAU-UHFFFAOYSA-N Diammonium sulfite Chemical compound [NH4+].[NH4+].[O-]S([O-])=O PQUCIEFHOVEZAU-UHFFFAOYSA-N 0.000 claims description 2
- PCNDJXKNXGMECE-UHFFFAOYSA-N Phenazine Natural products C1=CC=CC2=NC3=CC=CC=C3N=C21 PCNDJXKNXGMECE-UHFFFAOYSA-N 0.000 claims description 2
- YFPSDOXLHBDCOR-UHFFFAOYSA-N Pyrene-1,6-dione Chemical compound C1=CC(C(=O)C=C2)=C3C2=CC=C2C(=O)C=CC1=C32 YFPSDOXLHBDCOR-UHFFFAOYSA-N 0.000 claims description 2
- NRCMAYZCPIVABH-UHFFFAOYSA-N Quinacridone Chemical compound N1C2=CC=CC=C2C(=O)C2=C1C=C1C(=O)C3=CC=CC=C3NC1=C2 NRCMAYZCPIVABH-UHFFFAOYSA-N 0.000 claims description 2
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 claims description 2
- 150000004056 anthraquinones Chemical class 0.000 claims description 2
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical compound C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 claims description 2
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 claims description 2
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 2
- CZZYITDELCSZES-UHFFFAOYSA-N diphenylmethane Chemical compound C=1C=CC=CC=1CC1=CC=CC=C1 CZZYITDELCSZES-UHFFFAOYSA-N 0.000 claims description 2
- 150000002390 heteroarenes Chemical class 0.000 claims description 2
- RSAZYXZUJROYKR-UHFFFAOYSA-N indophenol Chemical compound C1=CC(O)=CC=C1N=C1C=CC(=O)C=C1 RSAZYXZUJROYKR-UHFFFAOYSA-N 0.000 claims description 2
- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 claims description 2
- 229960003151 mercaptamine Drugs 0.000 claims description 2
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 claims description 2
- 150000002791 naphthoquinones Chemical class 0.000 claims description 2
- DGBWPZSGHAXYGK-UHFFFAOYSA-N perinone Chemical compound C12=NC3=CC=CC=C3N2C(=O)C2=CC=C3C4=C2C1=CC=C4C(=O)N1C2=CC=CC=C2N=C13 DGBWPZSGHAXYGK-UHFFFAOYSA-N 0.000 claims description 2
- 125000002080 perylenyl group Chemical group C1(=CC=C2C=CC=C3C4=CC=CC5=CC=CC(C1=C23)=C45)* 0.000 claims description 2
- CSHWQDPOILHKBI-UHFFFAOYSA-N peryrene Natural products C1=CC(C2=CC=CC=3C2=C2C=CC=3)=C3C2=CC=CC3=C1 CSHWQDPOILHKBI-UHFFFAOYSA-N 0.000 claims description 2
- 239000000985 reactive dye Substances 0.000 claims description 2
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 claims description 2
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 claims description 2
- 229940001584 sodium metabisulfite Drugs 0.000 claims description 2
- 235000010262 sodium metabisulphite Nutrition 0.000 claims description 2
- AAAQKTZKLRYKHR-UHFFFAOYSA-N triphenylmethane Chemical compound C1=CC=CC=C1C(C=1C=CC=CC=1)C1=CC=CC=C1 AAAQKTZKLRYKHR-UHFFFAOYSA-N 0.000 claims description 2
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical group OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims description 2
- 150000001735 carboxylic acids Chemical class 0.000 claims 3
- 239000003638 chemical reducing agent Substances 0.000 claims 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 1
- 239000000999 acridine dye Substances 0.000 claims 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 150000004060 quinone imines Chemical class 0.000 claims 1
- 239000001016 thiazine dye Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 abstract description 24
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 54
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- 238000006243 chemical reaction Methods 0.000 description 28
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 description 28
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- 238000009472 formulation Methods 0.000 description 25
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 22
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- 235000010288 sodium nitrite Nutrition 0.000 description 14
- IUVCFHHAEHNCFT-INIZCTEOSA-N 2-[(1s)-1-[4-amino-3-(3-fluoro-4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)chromen-4-one Chemical compound C1=C(F)C(OC(C)C)=CC=C1C(C1=C(N)N=CN=C11)=NN1[C@@H](C)C1=C(C=2C=C(F)C=CC=2)C(=O)C2=CC(F)=CC=C2O1 IUVCFHHAEHNCFT-INIZCTEOSA-N 0.000 description 13
- 230000003647 oxidation Effects 0.000 description 13
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- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 12
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- XJHABGPPCLHLLV-UHFFFAOYSA-N benzo[de]isoquinoline-1,3-dione Chemical compound C1=CC(C(=O)NC2=O)=C3C2=CC=CC3=C1 XJHABGPPCLHLLV-UHFFFAOYSA-N 0.000 description 1
- PASDCCFISLVPSO-UHFFFAOYSA-N benzoyl chloride Chemical compound ClC(=O)C1=CC=CC=C1 PASDCCFISLVPSO-UHFFFAOYSA-N 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
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- 235000020279 black tea Nutrition 0.000 description 1
- 229910052796 boron Inorganic materials 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 150000007942 carboxylates Chemical class 0.000 description 1
- 229920006317 cationic polymer Polymers 0.000 description 1
- 229960002788 cetrimonium chloride Drugs 0.000 description 1
- WOWHHFRSBJGXCM-UHFFFAOYSA-M cetyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 description 1
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- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 description 1
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- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 description 1
- SGZVXLFVBKDMJH-UHFFFAOYSA-M dihydrogen phosphate;hexadecyl-(2-hydroxyethyl)-dimethylazanium Chemical compound OP(O)([O-])=O.CCCCCCCCCCCCCCCC[N+](C)(C)CCO SGZVXLFVBKDMJH-UHFFFAOYSA-M 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- IAZDPXIOMUYVGZ-UHFFFAOYSA-N dimethyl sulfoxide Natural products CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 description 1
- GLSRFBDXBWZNLH-UHFFFAOYSA-L disodium;2-chloroacetate;2-(4,5-dihydroimidazol-1-yl)ethanol;hydroxide Chemical compound [OH-].[Na+].[Na+].[O-]C(=O)CCl.OCCN1CCN=C1 GLSRFBDXBWZNLH-UHFFFAOYSA-L 0.000 description 1
- 150000002019 disulfides Chemical class 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
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- 239000011707 mineral Substances 0.000 description 1
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- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 description 1
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- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
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- 150000001451 organic peroxides Chemical class 0.000 description 1
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- 229940101267 panthenol Drugs 0.000 description 1
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- 235000020957 pantothenol Nutrition 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
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- 125000002958 pentadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000003538 pentan-3-yl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940067082 pentetate Drugs 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
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- QXYMVUZOGFVPGH-UHFFFAOYSA-N picramic acid Chemical compound NC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O QXYMVUZOGFVPGH-UHFFFAOYSA-N 0.000 description 1
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- RPDAUEIUDPHABB-UHFFFAOYSA-N potassium ethoxide Chemical compound [K+].CC[O-] RPDAUEIUDPHABB-UHFFFAOYSA-N 0.000 description 1
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- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 239000003531 protein hydrolysate Substances 0.000 description 1
- ROSDSFDQCJNGOL-UHFFFAOYSA-N protonated dimethyl amine Natural products CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 description 1
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- ZZYXNRREDYWPLN-UHFFFAOYSA-N pyridine-2,3-diamine Chemical class NC1=CC=CN=C1N ZZYXNRREDYWPLN-UHFFFAOYSA-N 0.000 description 1
- PZRKPUQWIFJRKZ-UHFFFAOYSA-N pyrimidine-2,4,5,6-tetramine Chemical class NC1=NC(N)=C(N)C(N)=N1 PZRKPUQWIFJRKZ-UHFFFAOYSA-N 0.000 description 1
- DQAKJEWZWDQURW-UHFFFAOYSA-N pyrrolidonecarboxylic acid Chemical class OC(=O)N1CCCC1=O DQAKJEWZWDQURW-UHFFFAOYSA-N 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 description 1
- NIKFYOSELWJIOF-UHFFFAOYSA-N rosanilin Chemical compound Cl.C1=C(N)C(C)=CC(C(=C2C=CC(=N)C=C2)C=2C=CC(N)=CC=2)=C1 NIKFYOSELWJIOF-UHFFFAOYSA-N 0.000 description 1
- 235000002020 sage Nutrition 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 1
- 229940083037 simethicone Drugs 0.000 description 1
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- ZRRGOUHITGRLBA-UHFFFAOYSA-N stattic Chemical compound [O-][N+](=O)C1=CC=C2C=CS(=O)(=O)C2=C1 ZRRGOUHITGRLBA-UHFFFAOYSA-N 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000012209 synthetic fiber Substances 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- KWXLCDNSEHTOCB-UHFFFAOYSA-J tetrasodium;1,1-diphosphonatoethanol Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P(=O)([O-])C(O)(C)P([O-])([O-])=O KWXLCDNSEHTOCB-UHFFFAOYSA-J 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 229940077400 trideceth-12 Drugs 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- LLWJPGAKXJBKKA-UHFFFAOYSA-N victoria blue B Chemical compound [Cl-].C1=CC(N(C)C)=CC=C1C(C=1C=CC(=CC=1)N(C)C)=C(C=C1)C2=CC=CC=C2C1=[NH+]C1=CC=CC=C1 LLWJPGAKXJBKKA-UHFFFAOYSA-N 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B44/00—Azo dyes containing onium groups
- C09B44/10—Azo dyes containing onium groups containing cyclammonium groups attached to an azo group by a carbon atom of the ring system
- C09B44/16—1,3-Diazoles or hydrogenated 1,3-diazoles ; (Benz)imidazolium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/10—Preparations for permanently dyeing the hair
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B44/00—Azo dyes containing onium groups
- C09B44/10—Azo dyes containing onium groups containing cyclammonium groups attached to an azo group by a carbon atom of the ring system
- C09B44/20—Thiazoles or hydrogenated thiazoles
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B49/00—Sulfur dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/94—Involves covalent bonding to the substrate
Definitions
- the present invention relates to novel sulfide dyes, compositions thereof, to processes for their preparation and to their use for the dyeing of organic materials, such as keratin fibers, wool, leather, silk, cellulose or polyamides, especially keratin-containing fibers, cotton or nylon, and preferably hair, more preferably human hair.
- organic materials such as keratin fibers, wool, leather, silk, cellulose or polyamides, especially keratin-containing fibers, cotton or nylon, and preferably hair, more preferably human hair.
- cationic dyes can be used to dye organic material, for example keratin, silk, cellulose or cellulose derivatives, and also synthetic fibers, for example polyamides. Cationic dyes exhibit very brilliant shades. A disadvantage is their unsatisfactory fastness to washing.
- the actual technical problem of the present invention was to provide dyes that are distinguished by deep dying having good fastness properties with respect to washing, light, shampooing and rubbing.
- the present invention relates to a method of dyeing keratin-containing fibers, comprising treating the fiber with at least one sulfide dye of formula
- Ri and R each independently from each other are a residue of an organic dye
- Yi and Y 2 each independently from each other are unsubstituted or substituted, straight- chain or branched, interrupted or uninterrupted -C C ⁇ 0 alkylene-; -C 5 -C 10 cycloalkylene-; C 5 -C ⁇ oarylene; or-C 5 -C ⁇ oarylene-(C ⁇ -C ⁇ oalkylene)-;
- Z 3 is hydrogen; and if n is 1.
- Z 3 is -S-; with the proviso that the method does not comprise treating the fiber with an enzyme of the type of a protein disulfidisomerase (EC 5.3.4.1).
- Yi and Y 2 are unsubstituted or substituted straight-chain or branched interrupted or uninterrupted ⁇ F-C 5 -C ⁇ 0 cycloalkylene- or -Gi-C-ioalkylene.
- Disulfid-dyes are used, i.e. wherein in formula (1 ) n is 1.
- Ri, R 2 , Zi, Z 2 , Yi, Y 2l r and q are defined as in formula (1). Further more preferred is the method of the present invention, wherein the residue of an organic dye is selected from the group of anionic, cationic, neutral, amphoter and zwitterionic dyes, and especially preferred, wherein the residue of an organic dye is a cationic dye.
- the residue of an organic dye is selected from the group of anthraquinone - acridine, azo, azomethine, hydra- zomethine, benzodifuranone, coumarine, diketopyrrolopyrrol, dioxaxine, diphenylmethane, formazan, indigoid, indophenol, naphthalimide, naphthoquinone, nitroaryl, merocyanine, methin, oxazine, perinone, perylene, pyrenequinone, prrtalocyanine, phenazine, quino- neimine, quinacridone, quinophtalone, styryl, triphenylmethan, xanthene, thiazine and thioxanthene dye.
- an organic dye is selected from the group of anthraquinone - acridine, azo, azomethine, hydr
- the residue of an organic dye is selected from azo, azomethin, hydrazomethin, merocyanine, methin and styryl dyes, and more preferred from azo, azomethin dye and hydrazomethin dyes;
- Suitable nitroaryl dyes of the present invention are for example selected from the following compounds:
- Suitable anthraquinone dyes suitable for the method of the present invention are the following compounds: 1-[(3-aminopropyl) amino]-anthraquinone (HC Red No. 7), 2-[(2- aminoethyl) amino]-anthraquinone (HC Orange No.
- Suitable azo dyes are for example the following compounds:
- Suitable cationic dyes are the following compounds: N-[4-[ [4-(diethylamino) phenyl] [4- (ethylamino)-naphth-l-yl] methylen]-2,5- cyclohexadien-1-yliden]-N-ethyl-ethanim inium- chloride (Basic Blue No.
- Re, R7. Rs. 9 , Rioand Rn independently from each other are hydrogen; unsubstituted or substituted C C ⁇ alkyl; C 2 -C ⁇ 4 alkenyl; C 5 -C ⁇ 0 aryl; d Ci 0 alkyl-C 5 -Ci 0 aryl; or C 5 -C ⁇ 0 aryl- CrC ⁇ 0 alkyl; and D + is a cationic radical of a substituted or unsubstituted aromatic or heterocyclic compound, wherein the cationic charge may be part of the aromatic compounds or part of the substituent; M is a bivalent radical of an aromatic or heteroaromatic substituted or unsubstituted compound; T is a radical of an aromatic substituted or unsubstituted compound; Q + is a cationic biradical of a substituted or unsubstituted aromnatic or heteroaromatic compound; and
- D is a radical of a cationic aromatic substituted or unsubstituted heterocyclic compound of formulae
- Q + is a cationic bivalent radical of an aromatic heterocyclic compound of formulae
- the asterix * indicates a bond to and/or Z 5 of formula (8); the asterix ** is a bond to Zi and/or Z 2 of formula (8); and M is a bivalent radical of formulae (D19) or
- the heteroaromatic cycles of the radicals of the formulae (D9) - (D22) may be interrupted by one or more than one -O-, -S-, -(SO 2 )-, -C C ⁇ 0 alkylene or -(NR 52 )-;
- D + is a radical of a cationic aromatic substituted or unsubstituted heterocyclic compound of formulae
- Q + is a cationic bivalent radical of an aromatic heterocyclic compound of formulae
- M is a bivalent radical of formulae (19)
- Z 7 , Z 8 , Z 9j Z ⁇ o, Z 11 , Z 12 , Z 13 and Z 14 are independently from each other N or a radical of CR 5 ⁇ ;
- E, E ⁇ , G and G 1 are independently from each other -O-, -S-, -(SO 2 )-, -C r C ⁇ 0 alkylene or -(NR 52 )-;
- Rl3. R 4. Rl5, Rl8, Rl9. R21. R-S, R23 ⁇ R25) R261 R27, R28J R29, R3O1 R3I1 R32J R33. R34j 35 ⁇ R36. R37 ⁇ R38, R39, R40, Rn. R42, R43, R44. R45, R.6, R47, R48.
- R49 and R ⁇ are independently from each other hydrogen; halogen; C C 4 alkyl, which is saturated or unsaturated, linear or branched, substituted or unsubstituted, or interrupted or uninterrupted with heteroatoms; a radical of phenyl, which substituted or unsubstituted; a of carboxylic acid radical; sulfonic acid radical; hydroxy; nitrile; C ⁇ -C ⁇ 6 alkoxy, (poly)-hydroxy-C 2 -C 4 -alkoxy; halogen; sulfonylamino; SR 60 . NHR53; NR S4 R 55 ; OR 61 ; SO 2 ; COOR 62 ; NR 56 COR 58 ; or CONR 57 ; and
- R12 R16, R17, R20, R2 j R50.
- R54J R55J R56J R57, R ⁇ j R ⁇ OJ R ⁇ i and R ⁇ 2 are each independently of the other hydrogen; unsubstituted or substituted C C ⁇ 4 alkyl, C 2 - C alkenyl, C 5 -C ⁇ 0 aryl, C 5 -C ⁇ oaryl-(CrC ⁇ oalkyl), or -C ⁇ -C ⁇ O alkyl(C 5 -C ⁇ 0 aryl); and
- An is an anion.
- D + is a radical of a cationic aromatic
- ** is a bond to and Zi and/or Z 2 of formula (8).
- M is a bivalent radical of formula
- ** is a bond to and Z and/or Z 2 of formula (7) or (8); and n is 1 or 0;
- T is a radical of formulae
- R 63 is hydrogen; unsubstituted or substituted d-C ⁇ 4 alkyl; C 5 -C 10 cycloalkyl; C -C 14 alkenyl; C 5 - C ⁇ 0 aryl-(CrC 10 alkyl); Crdoalky rCioaryl); C 5 -C 10 aryl; and R 64 is hydrogen; f unsubstituted or substituted, straight-chain or branched, interrupted or uninterrubted CrC 14 alkyl, C ⁇ -Ciocycloalkyl, C 5 -C ⁇ 0 aryl, or C 5 -Ci 0 aryl-(Ci-C 10 alkyl); d- C ⁇ 0 alkyl(C 5 -C ⁇ 0 aryI);
- R 67 is hydrogen; or a radical of formula (35a) ⁇ NR 69 ⁇ ; R 68
- Y 10 is unsubstituted or substituted, straight-chain or branched, monocyclic, from C 3 -alkyl upwards, or polycydic, from C 5 -alkyl upwards, interrupted or uninterrupted, d-C 10 alkylene; C 5 -C ⁇ 0 arylene-(CrC 10 alkylene); or-C 5 - C 10 arylene; and
- R 68 and R 6 gare each independently of the other hydrogen, unsubstituted or substituted d- C 14 alkyl, C 2 -C 4 alkenyl- -C 5 -C ⁇ oarylen-(C ⁇ -C ⁇ oalkyl), -C ⁇ -C ⁇ oalkylen(C5-doaryl), C 5 - C ⁇ 0 aryl,
- R71 is hydrogen; unsubstituted or substituted d-C ⁇ 4 alkyl; C 5 -C ⁇ 0 cycloalkyl; C 2 -C 14 alkenyl; C 5 - C 10 aryl; d-doalkyKCg-doaryl); C 5 -C ⁇ oaryl-(CrC ⁇ 0 alkyl); R 72 and R?
- C 3 are each independently of the other hydrogen; C C 4 alkyl; C 2 -C ⁇ alkenyl; a radical of acarboxylic; a radical of a sulfonic acid; C 5 -C ⁇ 0 aryl; hydroxy, nitril, CrC ⁇ 6 alkoxy, (poly)-hydroxy-C 2 -C 4 -alkoxy, carboxylic acid;; halogen; sulfonylamino; SR 6 o; NHR 53 ; NR 5 4R 55 ; OR 61 ; COOR 62 ; NR 5 6COR 58 ; or CONR 57 ; R53, R54, R55. R56. R57. 58.
- Reo, ei and R 62 are each independently of the other hydrogen; unsubstituted or substituted d-C ⁇ alkyl; C 2 -C ⁇ alkenyl; -C 5 -C ⁇ oarylen-(CrC 0 alkyl); -d- C oalkylene(Cs-C 10 aryl); orC 5 -C ⁇ 0 aryl;
- R 76 and R 77 are each independently of the other hydrogen, d-C 1 alkyl, which is saturated or unsaturated, linear or branched, substituted or unsubstituted, or interrupted or uninterrupted with heteroatoms; a radical of phenyl, which substituted or unsubstituted; a radical of carboxylic acid; C 5 -C ⁇ 0 aryl ; a radical of hydroxy, nitril, C ⁇ -C ⁇ 6 alkoxy, (poly)- hydroxy-C 2 -C 4 -alkoxy, carboxylic acid, sulfonic acid; halogen, sulfonylamino, SR 6 o, NHR 53 or NR 54 R 55 , OR 6 ⁇ , SO 2 , COOR 62J CONR 57 ; R53.
- Reo, Rei and R 62 are each independently of the other hydrogen, unsubstituted or substituted d-C ⁇ alkyl, C 2 -d alkenyl, -C 5 -C ⁇ oarylen-(C ⁇ -C ⁇ 0 alkyl), -C ⁇ - C 10 alkylen(C 5 -C ⁇ oaryl), C 5 -C ⁇ 0 aryl,
- R79, R78 and R 8 o are each independently of the other hydrogen; C ⁇ -C ⁇ 4 alkyl, which is saturated or unsaturated, linear or branched, substituted or unsubstituted, or interrupted or uninterrupted with heteroatoms; a radical of phenyl, which substituted or unsubstituted; a radical of carboxylic acid; C 5 -C ⁇ oaryl : a radical of hydroxy, nitril, d-d ⁇ alkoxy, (poly)- hy roxy-drd-alkoxy; carboxylic acid; sulfonic acid; halogen; sulfonylamino; SR 6 o; NHR 53 ; NR 54 Rs 5 ; OR 6 ⁇ ; SO 2 ; COOR 62 ; NR 56 COR58; or CONR 57 ;
- Rei and R 6 are each independently of the other hydrogen; unsubstituted or substituted C ⁇ -d alkyl; C 2 -C ⁇ 4 alkenyl; C 5 -C ⁇ oarylene-(C ⁇ -C 10 alkyl), d- C ⁇ oalkylene(C 5 -C ⁇ oaryl), C 3 -C ⁇ 0 aryl ;
- compounds o formula (35), wherein R 63 is methyl compounds of formula (36), wherein R 72 is hydrogen; and R 72 is in the para-postion of the phenyl moiety
- Ri and R 2 each independently from each other are a residue of an organic dye
- Yi and Y 2 independently from each other are C ⁇ -C ⁇ oalkylene
- Z and Z 2 independently from each other are -C(O)-; -C 2 -C ⁇ 2 alkenylene-; -(CH CH 2 -O) ⁇ - 5 -; CrC 1 oalkylene(C 5 -C 1 oarylene); C 5 -C 10 arylene; C 5 -docycloalkylene, -C(O)O-, -OCO-; R, -N(Rg)-; — N— ; -CO (R 4 )-; -(R 5 )NC(O)-; -O- -S-; -S(O)-; or -S(O) 2 -; 4 R 3 .
- Ri and R 5 are each independently from each other hydrogen; C -C ⁇ 4 alkyl; C 2 -C ⁇ alkenyl; C 6 -C 10 aryl; d-C 5 alkyl-C 5 -C ⁇ 0 aryl; or-C 5 -C ⁇ oC 5 -C ⁇ 0 aryl; r, q and n independently from each other are 0; or 1, if n is 0,
- Z 3 is hydrogen; and if n is 1 , Z 3 is -S-; are novel and represent another subject of the present inventio.
- the present invention also relates to the novel compounds of formulae (35), (36), (37) and (38).
- Alkylene is generally CrC 10 alkylene, for example methylene, ethylene, propylene, isopropylene- n-butylene, sec-butylene, tert-butylene, n-pentylene, 2-pentylene 3-pentylene, 2,2 , -dimethylpropylene, cyclopentylene, cyclohexylene, n-hexylene, n-octylene, " ⁇ ,V,3,3'- tetramethylbutylene, 2-ethylhexylene, nonylene or decylene.
- Alkylene may be straight-chain, branched, or, from C 5 alkyl upwards, monocyclic or polycyclic, and may be interrupted by hetero atoms, such as such as O, S, -CO-, N, NH, NR 5 ,-OCO-.
- C C ⁇ 0 alkylene may be a resisue such as: -CH 2 CH 2 -O-CH 2 CH 2 -O-CH 2 CH 2 - or -CH 2 CH 2 -O-CH 2 CH 2 - -CH 2 CH 2 -O-CH 2 - 1 -CH 2 -O-CH 2 -- -CH 2 CH 2 -CH 2 CH 2 -O-CH 2 -CH 2 -, -CH 2 CH 2 -CH(N(CH 3 ) 2 )-CH 2 -CH 2 - J CH 2 -NH 2 - CH 2 -CH 2l or-CH 2 CH 2 -NH-CH 2 CH2-, -CH2CH 2 -NCH 3 -CH 2 CH 2 -, or -CO-CH 2 -, or -CH 2 CO-, or -CH 2 CH 2 -NHCO-CH 2
- Arylene is generally C 6 -C ⁇ 0 arylene; for example phenyl or naphthyl;
- Aryl-alkylene is for example C 5 -doaryl-C -d 0 alkylene, Ce-Cioaryl-Ci-C-alkylene, alkyl-arylene is for example d-C ⁇ oalkyl-C 5 -C ⁇ oarylene or C ⁇ -C 2 alkyl-C 6 -C ⁇ 0 arylene.
- C ⁇ -Ciocycloalkylene is for example cyclopentylene, cyclohexylene, morpholylene or piperidinylene.
- subsituents may be chosen from the following groups: hydroxyl, C r C ⁇ 6 alkyl- C 5 -C 10 aryl, d-dealkoxy, - COOH, sulfonic acid, sulfonylamino, -SR 6 o,
- R4, R5. R54. R55 and R 6 o have the same defintion and preferences as given above.
- C ⁇ -C ⁇ 6 alkyl is for example, methyl, ethyl, propyl, isopropyl, n-butyl, sec-butyl, tert-butyl, n-pentyl, 2-pentyl, 3-pentyl, 2,2'-dimethyIpropyl J cyclopentyl, cyclohexyl, n-hexyl, n-octyl, l.l'.S.S'-tetramethylbutyl or 2-ethylhexyl, nonyl, decyl, undecy, dodecyl, tredecyl, tetradecyl, pentadecyl or haxadecly.
- d-C 6 alkoxy is O-C C 6 alkyI, preferably O-C ⁇ -C 4 alkyl.
- C 5 -C ⁇ oaryl-CrC 10 alkylene is, for example, phenyl-d-C ⁇ 0 alkylene or naphthyl-Ci-Cioalkylene.
- C 6 -d 0 aryl-CrC 2 alkylene and C ⁇ -C 2 alkyl-C 6 -C ⁇ oarylene are, for example, phenyl-C ⁇ - C ⁇ 0 alkylene or naphthyl-CrC ⁇ 0 alkylen.
- Halide is, for example, fluoride, chloride, bromide or iodide, especially chloride and fluoride.
- Alkalion denotes, for example, an organic or inorganic anion, such as halide, preferably chloride and fluoride, sulfate, hydrogen sulfate, phosphate, boron tetrafluoride, carbonate, bicarbonate, oxalate or d-C 8 alkyl sulfate, especially methyl sulfate or ethyl sulfate; anion also denotes lactate, formate, acetate, propionate or a complex anion, such as the zinc chloride double salt.
- halide preferably chloride and fluoride
- sulfate hydrogen sulfate
- phosphate phosphate
- boron tetrafluoride carbonate
- oxalate d-C 8 alkyl sulfate
- anion also denotes lactate, formate, acetate, propionate or a complex anion, such as the zinc chloride double salt.
- the anion is especially a halide, preferably chloride or fluoride, sulfate, hydrogen sulfate, methyl sulfate, ethyl sulfate, phosphate, formate, acetate or lactate.
- a halide preferably chloride or fluoride, sulfate, hydrogen sulfate, methyl sulfate, ethyl sulfate, phosphate, formate, acetate or lactate.
- the anion is more especially fluoride, chloride, methyl sulfate, ethyl sulfate, formate or acetate.
- protein disulfidisomerase (EC 5.3.4.1) is an enzyme of the enzym category EC 5.3.4.1. These enzymes preferably catalyse the ismerisation of intermolecular and intramolecular disulfid-bonds in proteinis.
- the EC (Enzyme commission) number is provided from the " Nomenclature Committee of the International Uniion of Biochemistry and Molecular Biology" (IUBMB).
- IUBMB Nomenclature Committee of the International Uniion of Biochemistry and Molecular Biology
- the residue of an organic dye is substituted or unsubstituted.
- biradical or radical of a heterocyclic compound is for example a biradical or radical of thiophenyl, 1,3-thiazolyl, 1,2-thiazolyl, 1,3-benzothiazolyl, 2,3- benzothiazolyl, imidazolyl, 1,3.4-thiadiazolyl, 1,3,5-thiadiazolyl, 1 ,3,4-triazolyl, pyrazolyl, benzimidazolyl, benzopyrazolyl, pyridinyl, quinolinyl, pyrimidinyl and isoxazolyl.
- Preferred biradical or radical of a heterocyclic compound is for example 1,3-thiazolyl, 1,2- thiazolyl, 1,3-benzothiazolyl, 2,3-benzothiazolyl, imidazolyl, 1,3,4-thiadiazolyl, 1,3,5- thiadiazolyl, 1,3,4-triazolyl, pyrazolyl, benzimidazolyl, benzopyrazolyl, pyridinyl, quinolinyl, pyrimidinyl and isoxazolyl. More preferred cationic heterocyclic compounds are imidazolyl, pyridinyl, 1,3,4-triazolyl and 1,3-thiazolyl.
- a biradical or radical of an aromatic compound is for example phenyl, naphthyl, thiophenyl, 1,3-thiazolyl, 1,2-thiazolyl, 1,3-benzothiazolyl, 2,3-benzothiazolyl, imidazolyl, 1 ,3,4-thiadiazolyl, 1,3,5-thiadiazolyl, 1,3,4-triazolyl, pyrazolyl, benzimidazolyl, benzopyrazolyl, pyridinyl, quinolinyl, pyrimidinyl and isoxazolyl, aminodiphenyl, aminodiphenylether or azobenzenyl.
- the biradical or radical of a heterocyclic or aromatic compound is unsubstituted or mono- or poly-substituted, for example by d-C 4 alkyl, C ⁇ -C alkoxy, C ⁇ -C alkylthio, halogen, e.g.
- a further emodiment of the present inveintion relates to processes for the preparation of the dyes of formula (1).
- a preferred process for the preparation comprises reacting a compound of formula (1a) with the compound of formula (1b) according to the following reaction scheme:
- a further preferred process for the preparation of compounds of formula (1) comprises reacting a compound of formula (1c) with the compound of formula (1d) according to the following reaction scheme:
- Li is a leaving group
- R L R 2 , Zi, Z 2 , Z 3 , Y I , Y 2) r, q and n are defined as in formula (1).
- the reaction is generally initiated by contacting; for example by mixing together the starting compounds or by dropwise addition of one starting compound to the other.
- the temperature is in the range of 273 to 300 K, preferably is in the range of 290 to 300 K during the mixing of the starting compounds.
- the reaction time is generally dependent on the reactivity of the starting compounds, on the reaction temperature chosen and on the desired conversion.
- the chosen duration of reaction is usually in the range from one hour to three days.
- the reaction temperature for the reaction of the compounds is advisable to select in the range from 273 to 340K, especially in the range from 273 to 335K.
- the reaction pressure chosen is generally in the range from 70 kPa to 10 MPa, especially from 90 kPa to 5 MPa, and is more especially atmospheric pressure.
- the molar ratio of compound of formula (1a) to the catalyst is generally selected in the range from 10:1 to 1 :5, especially in the range from 10:1 to 1 :1.
- Suitable catalysts are for example an alkali metal C ⁇ -C 6 alkyloxide, such as sodium-, potassium or lithium d-C 6 alkyloxide, preferably sodium methoxide, potassium methoxide or lithium methoxide, or sodium ethoxide, potassium ethoxide or lithium ethoxide; or tertiary amines, for example, such as chinuclidine, N-methylpiperidine, pyridine, trimethylamine, triethylamine, trioctylamine, 1,4-diazabicyclo[2.2.2]octan, chinuclidine, N-methylpiperidine; or alkalimetal acetate, for example such as sodium acetate, potassium acetate, or lithium acetate.
- alkali metal C ⁇ -C 6 alkyloxide such as sodium-, potassium or lithium d-C 6 alkyloxide, preferably sodium methoxide, potassium methoxide or lithium methoxide, or sodium
- reaction may be carried out with or without a solvent, but is preferably carried out in the presence of a solvent, preferably organic solvents or solvent mixtures.
- Solvents are organic solvents and water, or a mixture of organic solvents or a mixture of organic solvents and water.
- Organic solvents are for example, protic or aprotic polar organic solvents, such as alcohols, for example methanol, ethanol, n-propanol, isopropanol, butanol or glycols, especially isopropanol, or nitrile, such as acetonitrile or propionitrile, or amide, such as dimethylformamide, di- methylacetamide or N-methylpyridine, N-methylpyrolidon, or sulfoxide, such as dimethylsul- foxide, or mixtures thereof.
- protic or aprotic polar organic solvents such as alcohols, for example methanol, ethanol, n-propanol, isopropanol, butanol or glycols, especially isopropanol, or nitrile, such as acetonitrile or propionitrile, or
- the product prepared according to the process of the present invention may be advantageously worked up and isolated, and if desired be purified.
- the work up starts by decreasing the temperature of the reaction mixture in the range from 280 to 300 K, especially in the range from 290 to 300 K.
- reaction product is usually filtered and then washed with water or a salt solution and subsequently dried.
- Filtration is normally carried out in standard filtering equipment, for example B ⁇ chner funnels, filter presses, pressurised suction filters, preferably in vacuo.
- the temperature for the drying is dependent on the pressure applied. Drying is usually carried out in vacuo at 50-200 mbar.
- the drying is usually carried out at a temperature in the range from 313 to 363 K, especially from 323 to 353 K, and more especially in the range from 328 to 348 K.
- the product is purified by recrystallisation after isolation.
- Organic solvents and solvent mixtures are suitable for the recrystallisation, preferably alcohols, for example methanol, ethanol, 2-propanol or butanol, especially 2-propanol.
- the present invention also relates to a process for the preparation of compounds of formula
- (70) > which comprises a. acylating of 4-fluoro-3-nitroaniIine with an acylating agent as shown in the above formula b. hen reducing the nitro group to the amino group, c. then diazotizing the acylated 4-Fluoro-3-amino-aniline, and d. then coupling the diazotized with imidazole, and e. then alk lating the intermediate compound with an alkylating agent; or ai) diazotizing and coupling of a compound of formula, and then
- R 68 is hydrogen, unsubstituted or substituted C C ⁇ 4 alkyl, C 2 -d 4 alkenyl, -C 5 -C ⁇ oarylen-(d- Cioalkyl), C 5 -C ⁇ 0 aryl,
- acylation, reduction, diazotation, coupling and alkylation can be conducted by methods known per se.
- the dyes of formula (1) according to the invention are suitable for dyeing organic materials, such as keratin-containing fibers, wool, leather, silk, cellulose or polyamides, cotton or nylon, and preferably human hair.
- the dyeings obtained are distinguished by their depth of shade and their good fastness properties to washing, such as, for example, fastness to light, shampooing and rubbing.
- the stability, in particular the storage stability of the dyes according to the invention sre excellent.
- the multiplicity of shades of the dyes can be increased by combination with other dyes.
- the dyes of formula (1 ) of the present invention may be combined with dyes of the same or other classes of dyes, especially with direct dyes, oxidation dyes; dye precursor combinations of a coupler compound as well as a diazotized compound, or a capped diazotized compound; and/or cationic reactive dyes.
- Direct dyes are of natural origin or may be prepared synthetically. They are uncharged, cationic or anionic, such as acid dyes.
- the dyes of formula (1) may be used in combination with at least one single direct dye different from the dyes of formula (1).
- cationic nitroaniline and anthraquinone dyes are useful for a combination with a dye of formula (1).
- the dyes of formula (1 ) may also be combined with acid dyes, for example the dyes which are known from the international names (Color index), or trade names.
- These acid dyes may be used either as single component or in any combination thereof.
- the dyes of formula (1) may also be combined with uncharged dyes, for example selected from the group of the nitroanilines, nitrophenylenediamines, nitroaminophenols. anthra- quinones, indophenols, phenazines, phenothiazines, bispyrazolons, bispyrazol aza derivatives and methines.
- uncharged dyes for example selected from the group of the nitroanilines, nitrophenylenediamines, nitroaminophenols. anthra- quinones, indophenols, phenazines, phenothiazines, bispyrazolons, bispyrazol aza derivatives and methines.
- the dyes of formula (1) may also be used in combination with oxidation dye systems.
- Oxidation dyes which, in the initial state, are not dyes but dye precursors are classified according to their chemical properties into developer and coupler compounds. Suitable oxidation dyes are descri ed for example in
- Preferred developer compounds are for example primary aromatic amines, which are substituted in the para- or ortho- position with a substituted or unsubstituted hydroxy- or amino residue, or diaminopyridine derivatives, heterocyclic hydrazones, 4-aminopyrazol derivatives or 2,4,5,6-tetraaminopyrimidine derivatives.
- developer compounds in their physiological compatible acid addition salt form such as hydrochloride or sulfate can be used.
- Developer compounds, which have aromatic OH radicals are also suitable in their salt form together with a base, such as alkali metal- phenolates.
- Preferred developer compounds are disclosed in DE 19959479, p. 2, 1. 8 - 29.
- Preferred coupler compounds are m-phenylendiamine derivatives, naphthole, resorcine and resorcine derivatives, pyrazolone and m-aminophenol derivatives, and most preferably the coupler compounds disclosed in DE 19959479, p.1, 1. 33 to p. 3, 1. 11.
- autooxidizable compounds may be used in combination with the dyes of formula (1 ).
- Autooxidizable compounds are aromatic compounds with more than two substituents in the aomatic ring, which have a very low redox potential and will therefore be oxidized when exposed to the air.
- the dyeings obtained with these compounds are very stable and resistant to schampoo.
- Autooxidizable compounds are for example benzene, indol, or indol, especially 5,6- dihydroxyindol or 5,6-dihydroxyindol.
- the dyes of formula (1) may also be used in combination with naturally occurring dyes, such ashenna red, henna neutral, henna black, camomile blossom, sandalwood, black tea, Rhamnus frangula bark, sage, campeche wood, madder root, catechu, sedre and alkanet root.
- the dyes of formula (1) may also be used in combination with capped diazotised compounds.
- Suitable diazotised compounds are for example the compounds of formulae (1) - (4) in WO 2004/019897 (bridging gages 1 and 2) and the corresponding watersoluble coupling components (I) -(IV) as disclosed in the same reference on p. 3 to
- DC-01 WO 95/01772, wherein mixtures of at least two cationic dyes are disclosed, especially p. 2, 1. 7 to p. 4, 1. 1, preferably p.4, 1. 35 to p. 8, 1. 21 ; formulations p. 11, last ⁇ - p. 28, 1. 19;
- DC-02 US 6,843,256, wherein cationic dyes are disclosed, especially the compounds of formulae (1), (2), (3) and (4) (col. 1, 1. 27 - col. 3, 1. 20, and preferably the compounds as prepared in the examples 1 to 4 (col. 10, 1.42 to col. 13, 1.37; formulations col. 13, 1. 38 to col. 15, 1. 8;
- DC-03 EP 970685, wherein direct dyes are described, especially p.
- (DC-08): FR-2788432 wherein combinations of cationic dyes with Arianors are disclosed, especially p. 53, 1. 1 to p. 63, 1. 23, more especially p . 51 to 52, most especially Basic Brown 17, Basic brown 16, Basic Red 76 and Basic Red 118, and/or at least one Basic Yellow 57, and/or at least one Basic Blue 99; or com binations of arianoren and/or oxidative dyes, especially p. 2, 1. 16 to p. 3, 1. 16; dyeing formulations on p. 53, 1. 1 to p.63, 1. 23;
- DC-09 DE-A-19713 698, wherein the combinations of direct dyes and permanent-wave fixing comprising an oxidation agent, an oxidation dye and a direct dye are disclosed; especially p.4, 1. 65 to p. 5, 1. 59;
- DC-10 EP 850638, wherein developer compounds and oxidizing agents are disclosed; especially p. 2, 1. 27 to p. 7, 1. 46 and preferably p. 7, I. 20 to p. 9, 1. 26; dyeing formulations p. 2, 1. 3-12 and I. 30 to p. 14, and p.28, 1. 35 - p. 30, 1. 20; preferably p. 30, I. 25 - p. 32, 1. 30;
- DC-11 US 6,190,421 wherein extemporaneous mixtures of a composition (A) containing one or more oxidation dye precursors and optionally one or more couplers, of a composition (B), in powder form, containing one or more direct dyes (col.5, 1. 40 - col. 7, 1. 14), optionally dispersed in an organic pulverulent excipient and/or a mineral pulverulent excipient, and a composition (C) contain! ng one or more oxidizing agents are disclosed; formulations col. 8, 1. 60 - col. 9, 1. 56;
- DC-12 US 6,228,129, wherein a ready-to-use composition comprising at least one oxidation base, at least one cationic direct dye and at least one enzyme of the 2-electron oxidoreductase type in the presence of at least one donor for the said enzyme are disclosed; especially col. 8, 1. 17 - col. 13, 1. 65; dyei ng formulations in col. 2, 1. 16 to col. 25, 1. 55, a multi-compartment dyeing device is described in col. 26, 1. 13 - 24;
- DC-13 WO 99/20235, wherein compositions of at least one cationic dye and at least one nitrated benzene dye with cationic direct dyes and nitro benzene direct dyes are described; on p. 2, 1. 1 to p. 7, 1. 9, and p. 39, 1. 1 to p. 40 1. 11, preferably p. 8, 1. 12 to p. 25 I. 6, p. 26, 1. 7 to p. 30, 1. 15; p. 1, 1. 25 to p. 8, 1. 5 3 p. 30, 1. 17 to p. 34 I. 25, p. 8, 1. 12 to p. 25 I. 6, p. 35, 1. 21 to 27, especially on p. 36, 1. 1 to p. 37;
- DC-14 WO 99/20234, wherein compositions comprising at least one direct cationic dye and at least one autooxidisable dye, especially benzene, indol and indol. derivatives are described, preferably direct dyes on p. 2, 1. 19 to p.26, 1.4, and autooxidisable dyes as dislosed especially on p.26, 1. 10 to p. 28, 1. 15; dyeing formulations especially on p. 34, I. 5 to p. 35, li 18; (DC-15): EP 850636, wherein oxidation dyeing compositions comprising at least one direct dye and at least one meta-aminophenol derivative as coupler component and at least one developer compound and an oxidizing agent are disclosed, especially p. 5, 1.41 to p. 7, 1. 52, dyeing formulations p. 19, 1. 50 - p. 22, 1. 12;
- oxidation dyeing compositions comprising at least one oxidation base selected from para-phenylenediamines and bis(phenyl)alkylenediamines, and the acid-addition salts thereof, at least one coupler selected from meta-diphenols, and the acid-addition salts thereof, at least one cationic direct dye, and at least one oxidizing agent are disclosed, especially p. 6, 1.50 to p.8, 1.44 are discloseded; dyeing formulations p. 21, 1. 30 - p. 22, 1. 57;
- the dyes of formula (1) according to the present invention may be added to the dye combinations or dyeing formulations or may be replaced with at least one dye of formula (1).
- the present invention also releates to formulations, which are used for the dyeing of organic materials, preferably keratin-containing fibers, and most preferably human hair, comprising at least one dye of formula (1).
- the dyes of formula (1) are incorporated into the composition for treating organic material, preferably for dyeing in amounts of 0.001 - 5% b.w. (hereinafter indicated merely by "%"), particularly 0.005 - 4%, more particularly 0.2 - 3%, based on the total weight of the composition.
- the formulations may be applied on the keratin-containing fiber, preferably the human hair in different technical forms.
- Technical forms of formulations are for example a solution, especially a thickened aqueous or aqueous alcoholic solution, a cream, foam, shampoo, powder, gel, or emulsion.
- Customary the dyeing compositions are applied to the keratin-containing fiber in an amount of 50 to 100 g.
- formulations are ready-to-use compositions or multi-compartment dyeing devices or 'kits' or any of the multi-compartment packaging systems with compartments as described for example in US 6,190,421, col 2, 1. 16 to 31.
- the pH value of the ready-to-use dyeing compositions is usually from 2 to 11 , preferably from 5 to 10.
- One preferred embodiment of the present invention relates to the formulation of dyes, wherein the dyes of formula (1) are in powder form.
- Powder formulations are preferably used if stability and/or solubility problems as for example described in DE 197 13698, p. 2, 1.26 to 54 and p. 3, 1. 51 to p.4, 1. 25, and p. 4, 1.41 to p. 5 I. 59.
- Suitable cosmetic hair-care formulations are hair-treatment preparations, e.g. hair-washing preparations in the form of shampoos and conditioners, hair-care preparations, e.g. pre- treatment preparations or leave-on products such as sprays, creams, Qels, lotions, mousses and oils, hair tonics, styling creams, styling gels, pomades, hair rinses, treatment packs, intensive hair treatments, hair-structuring preparations, e.g. hair-waving preparations for permanent waves (hot wave, mild wave, cold wave), hair-straightening preparations, liquid hair- setting preparations, hair foams, hairsprays, bleaching preparations, e.g.
- hair-treatment preparations e.g. hair-washing preparations in the form of shampoos and conditioners
- hair-care preparations e.g. pre- treatment preparations or leave-on products such as sprays, creams, Qels, lotions, mousses and oils, hair tonics, styling creams, styling gels, po
- the dyeing compositions of the present invention can usually be incorporated into an aqueous cosmetic carrier.
- Suitable aqueous cosmetic carriers include, for example W/O, O/W, O/W/O, W/O/W or PIT emulsions and all kinds of microemulsions-, creams, sprays, emulsions, gels, powders and also surfactant-containing foaming solutions, e.g. shampoos or other preparations, that are suitable for use on keratin-containing fibers.
- surfactant-containing foaming solutions e.g. shampoos or other preparations
- Such forms of use are described in detail in Research Disclosure 42448 (August 1999).
- the dyei ng compositions according to the invention are also excellently suitable for the dyeing method described in DE-A-3 829870 using a dyeing comb or
- the constituents of the aqueous carrier are present in the dyeing compositions of the present invention in the customary amounts, for example emulsifiers may be present in the dyeing compositions in concentrations of from 0.5 to 30 % b.w. and thickeners in concentrations ef from 0.1 to 25 % b.w. of the total dyeing composition.
- the dyes of formula (1) may be stored in a liquid to paste-like preparation (aqueous or non- aqueous) or in the form of a dry powder.
- the preparation should be substantially anhydrous in order to reduce reaction of the compounds.
- the dyeing compositions according to the invention may comprise any active ingredients für additives or adjuvants known for such preparations, like surfactants, solvents, bases, acids, perfumes, polymeric adjuvants, thickeners and light stabilisers.
- non-ionic polymers non-ionic polymers
- cationic polymers acrylamide/dimethyldiallylammonium chloride copolymers
- quaternised polyvinyl alcohol quaternised polyvinyl alcohol, zwitterionic and amphoteric polymers .
- anionic polymers thickeners, structuring agents, hair-conditioning compounds, protein hydrolysates, perfume oils, dimethyl isosorbitol and cyclodextrins, solubilisers, anti-dandruff active ingredients, substances for adjusting the pH value; panthenol, pantothenic acid, allantoin, pyrrolidonecarboxylic acids and salts thereof, plant extracts and vitamins; cholesterol; light stabilisers and UV absorbers, consistency regulators, fats and waxes, fatty alkanolamides, polyethylene glycols and polypropylene glycols, complexing agents, swelling and penetration substances, opacifiers, such as latex; pearlising agents, propellants, antioxidants; sugar-containing polymers,quatemary ammonium salts, or bacteria inhibiting agents,.
- the dyeing compositions according to the present invention generally comprise at least one surfactant.
- Suitable surfactants are zwitterionic or ampholytic, or more preferably anionic, non-ionic and/or cationic surfactants.
- Suitable anionic surfactants are characterised by an anionic group that imparts water solubility, for example a carboxylate, sulfate, sulfonate or phosphate group, and a lipophilic alkyl group having approximately 10 to 22 carbon atoms.
- anionic group that imparts water solubility for example a carboxylate, sulfate, sulfonate or phosphate group, and a lipophilic alkyl group having approximately 10 to 22 carbon atoms.
- glycol or polyglycol ether groups, ester, ether and amide groups and also hydroxy groups may be present in t-he molecule.
- Preferred anionic surfactants are alkyl sulfates, alkyl polyglycol ether sulfates and ether carboxylic acids having 10 to 18 carbon atoms in the alkyl group and up to 12 glycol ether groups in the molecule, and also especially salts of saturated and especially unsaturated C 8 -C 22 carboxylic acids, such as oleic acid, stearic acid, isostearic acid and palmitic acid.
- nee is given the so-called betaines, such as the N-alkylN.N-dimethylammonium glycinates, for example cocoalkyldimethylammonium glycinate, N-acylaminopropyl-N,N-dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3- carboxymethyl-3-hydroxyethylimidazol.
- betaines such as the N-alkylN.N-dimethylammonium glycinates, for example cocoalkyldimethylammonium glycinate, N-acylaminopropyl-N,N-dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3- carboxymethyl-3-hydroxyethylimidazol.
- a preferred zwitterionic surfactant is the fatty acid amide derivative known by the CTFA name cocoamidopropyl betaine.
- Ampholytic surfactants are surface-active compounds that, in addition to a C 8 -C ⁇ 8 -alkyl or - acyl group and contain at least one free amino group and at least one -COOH or -SO 3 H group in the molecule and are capable of forming internal salts.
- ampholytic surfactants include N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids, each having approximately from 8 to 18 carbon atoms in the alkyl group.
- Ampholytic surfactants to which special preference is given are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and C 2 -C ⁇ 8 acylsarcosine.
- Non-ionic surfactants are described in WO 00/10519, especially p.45, 1. 11 to p. 50, I. 12.
- Non-ionic surfactants contain as hydrophilic group, for example, a polyol group, a polyalkylene glycol ether group or a combination of polyol and polyglycol ether groups.
- Examples of cationic surfactants that can be used in the dyeing compositions according to the invention are especially quaternary ammonium compounds.
- Alkylamidoamines, especially fatty acid amidoamines, such as the stearylamidopropyl- dimethylamine obtainable under the name Tego Amid ® 18 are alos proffered as surfactants in the present dyeing compositions. They are distinguished not only by a good conditioning action but also especially by their good biodegradability.
- a further preferred embodiment of the present invention relates to a method of treating keratin-containig fibers with sulfide dyes of formula (1).
- the method comprises treating the hair in the presence of a reduction agent.
- Preferred reduction agents are for example thioglycol acid or salts therof, gycerine monothioglycolat, cystein, 2-mercaptopropionic acid, 2-mercaptoethylamine, thiolactic acid, thioglycerine, sodium sulfite, dithionithe, ammonium sulfite, sodium bisulfite, sodium metabisulfite or hydrochinon.
- the present invention relates to a method of a. treating the keratin-containing fibers with a compound of formula (1 ), b. wearing the coloured hair for the desired period of time, c. removing the colour applied in step a) from hair by contacting the hair with an aqueous based colour removal composition containg a reduction agent capable of disrupting the - S-S-bonds between the dye molecule and the hair fiber surface to cause the dye molcule to become disassociated from the hair fiber.
- the present invention concerns a process, comprising treating the hair with a. a reduction agent, and b. at least a single sulfide dye of formula (1 ) as defined above, and optionally c. with an oxidizing agent.
- the sequence of the reaction steps is generally not important, the reduction agent can be applied first or in a final step.
- Preferred is a process, which comprises treating the hair a ) with at least one single dye of formula (1 ), and bi) then with a reduction agent; or a process, which comprises contacting hair a 2 ) with a reduction agent and b 2 ) then with at least one single sulfide dye of formula (1) as defined above.
- a process which comprises contacting hair a) with a reduction agent, b) then with at least one dye of formula (1), and c) then with an oxidizing agent.
- a further process of the present invention comprises contacting hair a) with at least one single dye of formula (1), and b) then with a reduction agent, and c) then with an oxidizing agent.
- the oxidizing agent is applied together with an acid or a base.
- the acid is for example citric acid, phosphoric acid or tartrate acid.
- the base is for example sodium hydroxide, ammonia or monoethanolamine.
- the dyeing compositions are applied to the keratin-containg fiber in an amount of from 50 to 100 g.
- the dyes of formula (1) are suitable for all-over dyeing of the hair, that is to say when dyeing the hair on a first occasion, and also for re-dyeing subsequently, or dyeing of locks or parts of the hair.
- the dyes of formula (1 ) are applied to on the hair for example by massage with the hand, a comb, a brush, or a bottle, or a bottle, which is combined with a comb or a nozzle.
- a process for dyeing keratin-containing fibers which comprises treating the keratin-containing fiber with at least one dye of formula (1 ), a base and an oxidizing agent.
- the oxidation dyeing process usually involves lightening, that is to say that it involves applying to the keratin-containing fibers, at basic pH, a mixture of bases and aqueous hydrogen peroxide solution, leaving the applied mixture to stand on the hair and then rinsing the hair. It allows, particularly in the case of hair dyeing, the melanin to be lightened and the hair to be dyed.
- the oxidizing agent containing composition is left on the fiber for 0 to 15 minutes, in particular for 0 to 5 minutes at 15 to 45°C, usually in amounts of 30 to 200 g.
- Oxidizing agents are for example persulfate or dilute hydrogen peroxide solutions, hydrogen peroxide emulsions or hydrogen peroxide gels, alkal. earth metal peroxides, organic peroxides, such as urea peroxides, melamine peroxides, or alkalimetalbromat fixations are also applicable if a shading powder on the basis of semi-permanent, direct hair dyes is used.
- Most preferred oxidizing agent is hydrogen peroxide, preferably used in a concentration from about 2 to 30 %, more preferably about 3 to 20% by, and most preferably from 6 to 12% b.w. the corresponding composition.
- the oxidizing agents may be present in the dyeing compositions according to the invention preferably in an amount from 0.01 % to 6 %, especially from 0.01 % to 1 %, based on the total dyeing composition.
- the dyeing with an oxidative agent is carried out in the presence of a base, for example ammonia, alkali metal carbonates, earth metal (potassium or lithium) carbonates, alkanol amines, such as mono-, di- or triethanolamine, alkali metal (sodium) hydroxides, earth metal hydroxides or compounds of the formula
- R is a propylene residue, which may be substituted with OH or d-C alkyl,
- R 3 , R ⁇ R 5 and R 6 are independently or dependently from each other hydrogen, d-C alkyl or hydroxy-(C ⁇ -C )al kyl .
- the pH-value of the oxidizing agent containing composition is usually about 2 to 7, and in particular about 2 to 5.
- One preferred method of applying formulations comprising the dyes of formula (1) on the keratin-containing fiber, preferably the hair is by using a multi-compartment dyeing device or "kit” or any other multi-compartment packaging system, as described for example in WO 97/20545 on p. 4, 1. 19 to I. 27.
- the present invention relates to a process of dyeing of keratin-containig fibers of the dyes of formula (1) with autooxidable compounds and optionally further dyes.
- the present invention relates to a process for dyeing keratin-containig fibers with the dyes of formula (1) and at least one acid dye.
- the following Examples serve to illustrate the processes for dyeing without limiting the processes thereto. Unless specified otherwise, parts and percentages relate to weight. The amounts of dye specified are relative to the material being coloured. T, s, d, q and J, wherein t is a triplett, s is singulett, d is duplett, q is a quartett, and J is a coupling constant, define the NMRspectra values.
- the obtained diazo solution is dropped to a 273 K cold solution of 7.4 g imidazole in 30 ml water, whereby the pH of the solution is maintained in the range of pH 10 to 11 by adding 36% of asodium hydroxide solution.
- the obtained suspension is warmed up to 295 K, the pH is adjusted to 10.5 with 36% sodium hydroxide solution.
- the suspension is filtered off and washed twice with 50 ml water to obtain 55 g of a humid product, which is suspended in 200 ml water and 3 weight equivalents dimethyl sulfate and sodium hydroxide are simultaneously added for maintaining the pH at 10-10.3 and the temperature at 298-303K.
- reaction is allowed to stand for one more hour to finish the hydrolysis of excess of dimethyl sulfate.
- the obtained diazo solution is dropped to a 273 K cold solution of 7.4 g imidazole in 30 ml water, whereby the pH of the solution is maintained in the range of pH 10 to 11 by adding 36% sodium hydroxide solution.
- the obtained suspension is warmed up to 295 K and the pH is adjusted to 10.5 with 36% sodium hydroxide solution.
- the suspension is filtered off and then washed twice with 50 ml water to obtain 55 g of the humid product, which is suspended in 500 ml water.
- 0.3 mol dimethyl sulfate and sodium hydroxide are simoultaniously added for maintaining the pH in the range of 10-10.3 and the temperature at 298-3O3K.
- the reaction mixture is hold for one hour. Then the water is evaporated. About 40 g humid solid, which gives 27 g of dryed product of the formula
- 11g cisteamin chlorohydrate are added to 27g of compound of formula (102a) in 20 g triethylamine and 120g isopropanol under nitrogen atmosphere at 293 K, .
- the temperature is raised to 333 K.
- the reaction mixture is stirred for 28 hours at this temperature.
- the reaction mass is stirred for 4 hours while the temperature is decreased to 295 K.
- the reaction mass is filtered off and the filter residue washed with 45 ml isopropanol and dried in vacuum to obtain 17.6 g of product f formula (102).
- the reaction mixture is stirred for further 3 hours.
- the hot mass is separated through filtration the residue washed with 100 ml ethanol.
- the filtrate and wash solution are cooled to 380 K with mixing, when cristallization of the product takes place.
- the product is separated by filtration, washed with cold ethanol and dryed in a vacuum dryer.
- the dried material is dissolved in 132 ml water and 110 ml of 32% hydrochloric acid at 295 K.
- the reaction mixture is cooled to 273 K and 86.4 g 36% sodium nitrite solution are dropped at such a rate that the temperature of the mixture is maintained in the range of 273 to 276 K.
- the mixture is further stirred for one hour. If no excess of nitrite is detected during one hour (detection by using a potassium iodide/starch paper) further amounts of sodium nitrite solution are added. After this one hour the remaining excess of nitrite is destroyed with sulfamic acid.
- the obtained diazo solution is dropped to a 273 K cold solution of 33.4 g imidazole in 130 ml water, whereby the pH of the solution is maintained in the range of pH 10 to 11 by adding 36% of a sodium hydroxide solution.
- the obtained suspension is warmed up to 295 K and the pH is adjusted to 10.5 with 36% sodium hydroxide solution.
- the suspension is filtered off and then washed twice with 100 ml water to obtain 200 g of the humid product.
- the filtercake from the previouse step is suspended in water and 3 weight equivalents dimethylsulfate and sodium hydroxide are simultaniously added for maintaining the pH in the range of 10-10.3 and the temperature at 300 K.
- the reaction mixture is hold for one more hour to finish the hydrolysis of excess of dimethylsulfate.
- the suspension is separated by filtration.
- About 240 g of a humid solid which gives 140 g dryed product of formula
- the acetyl derivative is solved in 520 ml ethanol and continuously added to 130 g iron in 35 ml concentrated chlorhidric acid and 220 ml water at 363K during 1 hour. The temperature drops to 353 K. The reaction mixture is stirred for further 3 hours. The hot mass is separated through filtration, the residuu washed with 100 ml ethanol. The filtrate and wash solution is cooled to 380 K with mixing, when cristallization of the product takes place. The product is separated by filtration, washed with cold ethanol and dryed in a vacuum dryer.
- the dried material is dissolved in 132 ml water and 110 ml of 32% hydrochloric acid at 295 K. Then the reaction mixture is cooled to 273 K and 86.4 g 36% sodium nitrite solution is dropped at such a rate that the temperature of the mixture is maintained in the range of 273 to 276 K. After the addition of the sodium nitrite solution, the mixture is stirred for one hour. If no excess of nitrite is detected during one hour (detection by using a potassium iodide/starch paper), further amounts of sodium nitrite solution is added. After this one hour the remaining excess of nitrite is destroyed with sulfamic acid.
- the obtained diazo solution is dropped to a 273 K cold solution of 33.4 g imidazole in 130 ml water, whereby the pH of the solution is maintained in the range of pH 10 to 11 by adding 36% sodium hydroxide solution.
- the obtained suspension is warmed up to 295 K, the pH is adjusted to 10.5 with 36% sodium hydroxide solution. After one hour stirring at this pH and temperature, the suspension is filtrated and then washed twice with 100 ml water to obtain 200 g of the humid product
- the filtercake from the previouse step is suspended in water and 3 weight equivalents dimethylsulphate and sodium hydroxide simoultaniously added for maintaining the pH in the range of 10-10.3 and the temperature at 300 K. Then, the reaction mixture is hold for one more hour, to finish the hydrolysis of excess of dimethylsulphate. Then, the suspension is separated by filtration. About 240 g humid solid, which gives 140 g dryed product of formula
- the reaction mixture is stirred for further 3 hours.
- the hot mass is separated through filtration, the residue washed with 100 ml ethanol.
- the filtrate and wash solution are cooled to 380 K with mixing when cristalliziation of the product takes place.
- the product is separated by filtration, washed with cold ethanol and dryed in a vacuum dryer.
- the dried material is dissolved in 132 ml water and 1 10 ml of 32% hydrochloric acid at 295 K.
- the reaction mixture is cooled to 273 K and 86.4 g of a 36% sodium nitrite solution are dropped at such a rate that the temperature of the mixture is maintained in the range of 273 to 276 K.
- the mixture is stirred for one hour.
- Alkylating agent A mixture of 15.4 g of 2.2-dithiodiethanol in 100 ml chloroform and 24.1 g pyridine are cooled with stirring at 273K and then 41 .0 g of tosyl chloride are added in small amounts, maintaining the temperature. After completion of the addition the mixture is left over night in the refrigerator. The reaction mixture is mixed with a water/hydrochloric acid/ice slurry. The phases are separated, washed with water and dried. The obtained solution of toluenesulfonate diester is used in the 3. step.
- the pH of the solution is raised to the range of 5 to 6 by adding 36% sodium hydroxide solution. After one hour stirring at this pH and temperature the suspension is filtered off and then washed twice with 50 ml -water to obtain 155 g of the humid product. After drying 100 monoazo dye is obtained.
- Alkylating agent A mixture of 15.4 g of 2,2-dithiodiethanol in 100 ml chloroform and 24,1 g pyridine are cooled with stirring to 273 K and then 41.0 g of tosyl chloride are added in small amounts maintaining the temperature.
- Alkylating agent A mixture of 21.4 g of 2.2-dithiodiethanol in 100 ml chloroform and 24.1 g pyridine are cooled with stirring to 273K and then 41.0 g of mesyl anhydride are added in small amounts under constant temperature.
- Alkylating agent A mixture of 15.4 g of 2.2-dithiodiethanol in 100 ml chloroform and 24.1 g pyridine are cooled with stirring to 273K and then 41.0 g of tosyl chloride are added in small amounts under constant temperature.
- Alkylating agent A solution of 22.5 g of cisteamine dichlorohydrate in water and 31.4 g bromoacetic chloride are cooled with stirring to 273K and then the pH is kept constant by adding NaOH solution in small amounts under constant temperature. After completion of the addition the mixture is left over night in the refrigerator. The mixture has two phases, which are separated, washed with water and dried. 3. Alkylation: The foregoing hydrazone is dissolved in methanol by stirring with the dibromide solution. The temperature is raised to 60°C and maintained at 60°C during the following 24 hours. The crystals separated in the slurry are filtrated. The product is washed with 50 ml of methanol and dried in vacuum to obtain 49 g of an orange solid product. The product is recristallized twice from methanol.
- Alkylating agent A mixture of 15.4 g of 2.2-dithiodiethanol in 100 ml chloroform and 24,1 g pyridine is cooled with stirring to 273K and then 41.0 g of tosyl chloride are added in small amounts under constant temperature. After completion of the addition the mixture is left over night in the refrigerator. The reaction mixture is mixed with a water/chlorhidric acid/ice slurry, the phases are separated, washed with water and dried. The obtained solution of methane- benzene-sulfonate diester is used in the following step 3.Alkylation: Stirring into the diester solution in chloroform dissolves two equivalents of the foregoing monoazo.
- the temperature is raised to 333K and maintained at 333K during the following 20 hours. Crystals separated in the slurry are filtrated. The product is washed with 50 ml of chloroform and dried in vacuum to obtain 80 g of a dark solid product, which is recristallized twice from methanol.
- the compound of formula (104a) (prepared in example A 4) is reacted with N.N-dimethyl- ethylendiamine according to the method as described in Example A14.
- the same alkylating agent is used and the compound of formula (116) is obtained.
- Example B Application Examples: The washing fastness of the dyed hair is analyzed by the Grey scale according to Industrial organic pigments by Herbst&Hunger, 2nd ed. engl. S. 61) Nr 10: DIN 54001-8-1982,whoHer- wolf undenne der Ae precise der91", ISO 105-A02-1993. ln the following application examples compositions with definitions the below given are used:
- Solution (1) (permanent lotion, pH 8.2): Aqua, Ammonium Thioglycolate, Ammonium Bicarbonate, Ethoxydiglycol, Hexylene Glycol, ThioglycolicAcid; Thiolactic Acid, PEG-60 Hydrogenated Castor Oil, Glycine, Etidronic Acid, lsoceteth-20, Polysilicone-9, Styrene/PVP Copolymer, Trideceth-12, Amodimethicone, Cetrimonium Chloride, Ammonium Hydroxide, Polyquaternium-6, Isopropyl Alcohol, Alcohol denat., Simethicone, perfume
- Solution (2) (permanent fixation, pH 3.9): Based on: Aqua, Hydrogen Peroxide, Propylene Glycol, Lauryldimonium Hydroxypropyl Hydrolyzed Wheat Protein, PEG-5 Cocamide, Sodium Cocoamphoacetate, Polyquaternium-35, Coco-Betaine, Acetaminophen, Phosphoric Acid, Sodium Chloride, perfume
- Solution (3) (dyeing solution): 0.1 % of the dye is dissolved in a 10 % solution of a non-ionic surfactant (Plantacare 200UP, Henkel) adjusted to pH 9.5 using citric acid or monoethanol- amine.
- a non-ionic surfactant Plantacare 200UP, Henkel
- Solution (4) (permanent lotion, pH 8.7): Aqua, Thioglycolic Acid, Ammonium Bicarbonate, Ammonium Hydroxide, PEG-60 Hydrogenated Castor Oil, Sericin, Polyquatemium 22, Lauryldimmonium Hydroxypropyl Hydrolyzed Keratin, Hydroxyethyl Cetyldimonium Phosphate, Sodium Cocoamphopropionate, perfume/Fragance, Styrene/PVP Copolymer, Pantasodium Pentetate, Ascorbic Acid, Benzyl Salicilate, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Hexyl Cinnamal, Butylphenyl Methylprpional, Linalool.
- Solution (5) (permanent fixation, pH 2.9): Based on: Aqua, Hydrogen Peroxide, Hydroxycetyl Hydroxyethyl Dimonium Chloride, Tetrasodium Etidronate, PEG-40 hydrogenated Castor Oil, Salicylic Acid, Tetrasodium EDTA, Styrene/PVP Copolymer, Sericin, Salicylic Acid, Tetrasodium EDTA, Styrene/PVP Copolymer, Sericin, Salicylic Acid, Tetrasodium EDTA, Styrene/PVP Copolymer, Sericin, Salicylic Acid, Tetrasodium EDTA, Styrene/PVP Copolymer, Sericin, Salicylic Acid, Tetrasodium EDTA, Styrene/PVP Copolymer, Sericin, Salicylic Acid, Tetrasodium EDTA, Styrene/PVP Copolymer, Sericin, Salicylic Acid, Tetrasodium
- Placebo colouring material Obtained by adding 11 ml ammonia solution (25% b.w.) at 343K to a composition consisiting of ammonium chloride 0.5% b.w., tetrasodium EDTA, 0.2% b.w., silica 0.1% b.w., water, add100% b.w..
- the obtained mixture is added to a composition consisting of cetearyl alcohol, 11% b.w., oleth-5, 5% b.w., oleic acid, 2.5% b.w., stearamide MEA, 2.5% b.w., cocoamide MEA, 2.5% b.w., propylene glycol 1.0% b.w..
- Colouration composition of a placebo The colouration composition of a placebo is obtained by adding 11 ml ammonia solution (25% b.w.) at 343K to a composition consisiting of ammonium chloride 0.5% b.w., tetrasodium EDTA, 0.2% b.w., silica 0.1% b.w., water, add100% b.w. and 0.2% b.w.
- a tress of human hair, bleached white, is shampooed. Then, the towel dried hair tress is put on the glass plate.
- Solution (1) is applied to the wet hair tress. After 10 min the hair tress is rinsed under tap water and pressed out with a paper towel. Afterwards the tress is treated with a solution 3 containing the dye of formula (101) (Example A1) for 20 min and then rinsed with water. Then solution (2) is applied to the towel dried hair tress. After 10 minutes the hair tress is rinsed under tap water again and dried. The tress is very intensive red with a very good wash fastness.
- a tress of blonde undamaged human hair is shampooed. Then the towel dried hair tress is put on the glass plate.
- the solution (1) (permanent solution) is applied to the wet hair tress. After 10 min the hair tress is rinsed under tap water and pressed out with a paper towel. Afterwards the tress is treated with a solution 3 containing the dye from Example A2 for 20 min and then rinsed with water. Then solution (2) (permanent fixation) is applied to the towel dried hair tress. After 10 min. the hair tress is rinsed under tap water again and dried. The tress is very intensive violet with a very good wash fastness.
- solution (1) permanent lotion having a pH 8.2, which is mixed with a weight equivalent water to give a pH of 8.00 is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Then the strands are rinsed
- a solution 1 (permanent lotion) having a pH 8.2 is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Then, the strands are rinsed under tap water, and the towel dry strands are treated with a colouring material solution consisting of a. compound of formula (101) according to example A1 , 0.2%, b.w. solution in plantaren, and b. a watery hydrogene peroxid solution, 6% b.w., which are mixed together in a weight ratio of 1:1, and then applied on the hair and allowed to stand for 30 min, and then, rinsed and then shampooed, and afterwards dried for 12 hours at room temperature.
- a colouring material solution consisting of a. compound of formula (101) according to example A1 , 0.2%, b.w. solution in plantaren, and b. a watery hydrogene peroxid solution, 6% b.w.
- Solution 1 (permanent lotion; pH 8.2) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Then the strands are rinsed under tap water and the towel dry strands treated with a colouring material solution consisting of a. compound of formula (101) according to example A1 , 0.2%, b.w. solution in plantaren, and b. placebo colouring material, which are mixed together in a weight ratio of 1 :1 , and then applied on the hair and allowed to stand for 30 min. and then rinsed.
- a colouring material solution consisting of a. compound of formula (101) according to example A1 , 0.2%, b.w. solution in plantaren, and b. placebo colouring material, which are mixed together in a weight ratio of 1 :1 , and then applied on the hair and allowed to stand for 30 min. and then rinsed.
- Solution (1) permanent lotion; pH 8.2
- shampooed hair two blond, two middle blond and two damaged hair strands
- strands are rinsed under tap water and the towel dry strands are treated with a 0.1%, b.w. colouring material solution consisting of the compound of formula (101) insolution (2) (permanent fixation) and allowed to stand for 20 min.
- strands are rinsed under tap water and dried 12 hours at room temperature.
- Application Example B15 A composition consisting of a. a solution 1 (permanent lotion), having a pH 8.2, and b. a 0.2%, b.w. solution of compound of formula (101) in plantaren, which are mixed together in a weight ratio of 1:1 is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Then, the strands are rinsed under tap water. The towel dry strands are treated with a solution 2 (permanent fixation), and allowed to stand for 10 min. Then the strands are rinsed under tap water and dried 12 hours at room temperature.
- a solution 1 permanent lotion
- b. a 0.2% b.w. solution of compound of formula (101) in plantaren
- a solution (1) permanent lotion
- b. 0.1% b.w. solution of the compound of formula (101) in plantaren which are mixed together in a weight ratio of 1 :1
- shampooed hair two blond, two middle blond and two damaged hair strands
- the towel dry strands are treated with a solution (2) (permanent fixation), and allowed to stand for 10
- a solution 1 (permanent lotion; pH 8.2) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min. Then the strands are rinsed under tap water and the towel dry strands are treated with a 0.1%, b.w. colouring material solution of compound of formula (101) in solution (2) (permanent fixation) and allowed to stand for 20 min. Then the strands are rinsed under tap water. The towel dry strands are treated with a composition consisting of a. a placebo colouring material and b. a aqueous hydrogen peroxide solution, 12 % b.w., and having a weight ratio of the placebo to the hydrogene peroxide solution of 1 :1. Then the strands are allowed to stand for 30 min. The strands are rinsed under tap water, shampooed and dried 12 hours at room temperature.
- Solution (1) (permanent lotion; pH 8.2) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Then the strands are rinsed under tap water and the towel dry strands are treated with a 0.1% b.w. colouring material solution of compound of formula (101) in solution (2) (permanent fixation) and allowed to stand for 20 min. Then the strands are rinsed under tap water. The towel dry strands are treated with a fixation composition consisting of a) ammonia and b) an aqueous hydrogen peroxide solution having a pH of 9.8. Then the strands are allowed to stand for 10 min. The strands are rinsed under tap vwater, shampooed and dried 12 hours at room temperature.
- a colouring material solution consisting of a. 25 ml of a 0.1% b.w. solution of compound of formula (101), and b. 25 ml of a 0.1% b.w. solution of compound of formula (106) is applied on dry hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 30 min.
- a solution 1 (permanent lotion; pH 8.2) is a plied on shampooed hair (two blond, two middle blond and two damaged hair strands) and al lowed to stand for 10 min. Then the strands are rinsed under tap water, and the towel dry strands are treated with a colouring material solution consisting of a. 25 ml of a 0.1% b.w. solution of compound of formula (101) according to example A1 in plantaren, and b. 25 ml of a ⁇ .1% b.w. solution of compound of formula (106) according to example A6 in plantaren solution, allowed to stand for 20 min and then rinsed.
- a colouring material solution consisting of a. 25 ml of a 0.1% b.w. solution of compound of formula (101) according to example A1 in plantaren, and b. 25 ml of a ⁇ .1% b.w. solution of compound of formula (106) according to example A6 in plantaren solution, allowed to stand for
- the towel dry strands are treated with a solution (2) (permanent fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- the strands are rinsed under tap water.
- the towel dry strands are treated with a solution (5) (permanent fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- a solution (1) (permanent lotion; pH 8.2) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min.
- the strands are rinsed under tap water and the towel dry strands treated with a colouring material solution consisting of a. 0.2% b.w. solution of compound of formula (101) according to example A1, in plantaren, and b. placebo colouring material, which are mixed together in a weight ratio of 1:1, and then applied on the hair and allowed to stand for 20 min and then rinsed.
- the towel dry strands are treated with a solution 2 (permane- nt fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- Solution (1) (permanent lotion; pH 8.2) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Tthe strands are rinsed under tap water and the towel dry strands treated with) a colouring material solution consisting of a. 0.2% b.w. solution of compound of formula (101) according to example A1, in plantaren, and b placebo colouring material, which are mixed together in aweight ratio of 1 :1 , and then, applied on the hair and allowed to stand for 10 min and then rinsed. Then the towel dry strands are treated with solution (2) (permanent fixation) and allowed to stand for 10 min. Then the strands are rinsed under tap water and dried 12 hours at room temperature.
- a colouring material solution consisting of a. 0.2% b.w. solution of compound of formula (101) according to example A1, in plantaren, and b placebo colouring material, which are mixed together in aweight ratio of 1 :1
- Solution (1 ) (permanent lotion) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 1 0 min.
- the strands are rinsed under tap water and the towel dry strands treated with a Q».1% b. w. colouring material solution of the compound of formula (101) in plantaren, allowed to stand for 20 min and then rinsed.
- the towel dry strands are treated with a solution 2 (permanent fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- Solution (4) (permanent lotion; pH 8.7) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 15 min.
- the strands are rinsed under tap water, and the towel dry strands treated with a colouring material solution consisting of a 1.6 weight equivalents of a 0.1% b.w. solution of compound of formula ⁇ 101) according to example A1 in plantaren solution, b) 5 weight equivalents of of a 0.1% b.w. solution of compound of formula (106) according to example A6 in plantaren solution, and c) 1.5 weight equivalents of a 0.1% b.w. solution of compound of formula (103) according to example A3 in plantaren solution, and allowed to stand for 20 min. and then rinsed.
- the towel dry strands are treated with solution (5) (permanent fixation; pH 2.9) and allowed to stand for 10 min. Trie strands are rinsed under tap water and dried for 12 hours at room temperature.
- a colouring material solution consisting of a 1.6 w. eq. of a 0.1% b.w. solution of the compound of formula (101) in plantaren, and b.5 w. eq. of of a 0.1% b.w. solution of compound of formula (106) in plantaren, c. 1.5 w. eq. of a 0.1% b.w. solution of compound of formula (103) in plantaren solution, is applied on dry hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min.
- Hair (blond strand, damaged strand) is shampooed, rolled on curls windings and then treated with solution (4) (permanent lotion; pH 8.7) and then allowed to stand for 10 min.
- the hair is treated with a 0.1% b.w. solution of compound of formula (101) in plantaren and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water, and the towel dry strands treated with a solution 5 (permanent fixation; pH 2.9) and allowed to stand for 5 min.
- Curl windings are removed and the hair is again treated with solution (5) (permanent fixation; pH 3.92) and allowed to stand for 5 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- the strands are curled and red coloured.
- Hair (blond strand, damaged strand) is shampooed and then rolled on curls windings and treated with solution (4) (permanent lotion; pH 8.7 which is diluted with 2 weight equivalents of water and then allowed to stand for 5 min.
- the hair is treated with 0.1% b.w. solution of compound of formula (101) in plantaren and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water and the towel dry strands are treated with solution (5) (permanent fixation; pH 2.9) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- Hair (blond strand, damaged strand) is shampooed and then rolled on curls windings and treated with solution (4) (permanent lotion; pH 8.7), which is diluted with 2 weight equivalents of water and allowed to stand for 10 min.
- solution (4) permanent lotion; pH 8.7
- the hair treated with 0.1% b.w. solution of the compound of formula (101) in plantaren and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water and the towel dry strands are treated with solution (5) (permanent fixation; pH 2.9) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- a solution 1 permanent lotion
- B. a 0.2% b.w. solution of compound of formula (101) in plantaren which are mixed together in a weight ratio of 1 :2 of component a) to b
- a composition consisting of 30 g of a 0.1% b. w. solution of the compound of formula (10 1) in plantaren having a pH of 6.12 is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min. The strands are rinsed under tap water and dried 12 hours at room temperature.
- a composition comprising 49.95 g of a 0.1%, b.w. solution of the compound of formula (101) in plantaren having a pH of 6.1, and
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- 0.55g ammonium thioglycolate solution, and ammonia and citronic acid for adjusting the pH to 8.0, is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min.
- the strands are rinsed under tap water.
- the towel dry strands are treated with solution (2) (permanent fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- Example B37 10% b.w. of a solution of sodium sulfite in water having a pH of 8 (the pH is adjusted by ammonia and citric acid) is applied on shampooed hair (blond strand, damaged strand) and allowed to stand for 10 min.
- the hair is rinsed and treated then with 0.1% b.w. of a solution (pH 9.5) of the compound of formula (101) and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water and the towel dry strands are treated with solution (5) (permanent fixation) having a pH 2.9 and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- 0.05g of a 0.1% b.w. solution of sodium sulfite in water having a pH of 8 (the pH is adjusted by ammonia and citric acid), is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min.
- the hair is rinsed under tap water and the towel dry strands are treated with solution (5) (permanent fixation) having a pH 2.9 and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- the hair is rinsed under tap water and the towel dry strands are treated with a solution 2 (permanent fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- 2% b.w. of a solution of sodium sulfite in water having a pH of 8 (the pH is adjusted by ammonia and citric acid) is applied on shampooed hair (blond strand, damaged strand) and then allowed to stand for 10 min.
- the hair is rinsed and treated then with 0.1% b.w. of a solution of the compound of formula (101) (pH 9.5) and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water and the towel dry strands treated with solution (2) (permanent fixation) having a pH 3.92 and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- 2% b.w. of a solution of ammonium thioglycolate in water (pH 8; adjusted with ammonia and citric acid) is applied on shampooed hair (blond strand, damaged strand) and then allowed to stand for 10 min.
- the hair is rinsed and treated with 0.1% b.w. of a solution of the compound of formula (101) according in plantaren (pH 9.5) and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water and the towel dry strands are treated with solution (2) (permanent fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- 2% b.w. of a solution of ammonium thiolactate in water (pH of 8; adjusted by ammonia and citric acid) is applied on shampooed hair (blond strand, damaged strand) and then allowed to stand for 10 min.
- the hair is rinsed and treated with 0.1% b.w. of a solution of the compound of formula (101) in plantaren (pH 9.5) and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water and the towel dry strands treated with solution (2) (permanent fixation) and allowed to stand for 10 min. Then the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- composition comprising
- composition comprising
- 0.05g of a 0.1 % b.w. solution of ammonium thioglycolate in water (pH 8.0; adjusted by ammonia and citric acid), is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min. Then the hair is rinsed under tap water and the towel dry strands treated with a composition comprising component a) and b) in a weight ratio of 1 :1, wherein a) is hydrogene peroxide, 6% b.w. solution in water, and b) is a colouration composition of a placebo and then are allowed to stand for 30 min. Then the strands are rinsed under tap water and dried 12 hours at room temperature.
- a solution of 0.1% b.w. of the compound of formula (101) in plantaren pH 8; pH is adjusted with ethanol amin
- shampooed hair two blond, two middle blond and two damaged hair strands
- the hair is rinsed under tap water and dried 12 hours at room temperature.
- a solution of 0.1% b.w. of the compound of formula (101) (pH 8; adjusted with ethanolamine) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min.
- the hair is rinsed under tap water and the towel dry strands treated with a composition comprising component a) and b) in a weight ratio of 1:1, wherein a) is hydrogen peroxide, 6% b.w. solution in water, and b) is a colouration composition of a placebo and are allowed to stand for 30 min.
- the strands are rinsed under tap water and dried for 12 hours at room temperature.
- composition comprising
- a solution of 0.1% b.w. of the compound of formula (101) in plantaren (pH of 5.5; adjusted with ethanolamin) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min. Then the hair is rinsed under tap water and the towel dry strands are treated with a composition comprising component a) and b) in a weight ratio of 1:1, wherein a) is hydrogen peroxide, 6% b.w. solution in water, and b) is a colouration composition of a placebo and then allowed to stand for 30 min. The strands are rinsed under tap water and dried for 12 hours at room temperature.
- composition comprising
- the strands are rinsed under tap water and dried for 12 hours at room temperature.
- composition comprising
- 0.85g of a 0.1% b.w. solution of ammoniumthiolactate in water pH 8.0; adjusted with ammonia and citric acid
- shampooed hair two blond, two middle blond and two damaged hair strands
- the hair is rinsed under tap water and the towel dry strands treated with a solution (2) (permanent fixation) and allowed to stand for 10 min..
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- 0.1% b.w. of a solution of ascobinic acid in water pH 8; adjusted by ammonia and citric acid
- shampooed hair Blond strand, damaged strand
- the hair is rinsed and treated then with 0.1% b.w. of a solution of compound of formula (101) according to example A1 in plantaren (with pH 6.1), and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water, and the towel dry strands are treated with a solution 2 (permanent fixation) and allowed to stand for 10 min.
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- 2% b.w. of a solution of hydrochinon in water (pH 8; adjusted by ammonia and citric acid) is applied on shampooed hair (blond strand, damaged strand) and then allowed to stand for 10 min.
- the hair is rinsed and treated with 0.1% b.w. of a solution of the compound of formula (101) in plantaren solution (with pH 6.1) and allowed to stand for 20 min at room temperature.
- the hair is rinsed under tap water and the towel dry strands treated with a fixating solution (Goldwell) having a pH 3.92 and allowed to stand for 10 min. Then the strands are rinsed under tap water and dried 12 hours at room temperature.
- Test 1 A solution 1 (permanent lotion; pH 8.2) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Then the strands are rinsed under tap water, and the towel dry strands are treated with a 0.1 % b.w. colouring material solution of a compound of formula (102) according to example A2, in plantaren and allowed to stand for 20 min. and then rinsed. The towel dry strands are treated with a solution (2) (permanent fixation) and allowed to stand for 10 min. Then the strands are rinsed under tap water and dried for 12 hours at room temperature.
- a solution 1 permanent lotion; pH 8.2
- a solution (2) permanent fixation
- Test 2 Solution (1) (permanent lotion; pH 8.2) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min..
- the wet strands are treated with a colouring material solution consisting of a 0.1%, b.w. colouring material solution of the compound of formula (102) in plantaren and allowed to stand for 20 min. and then rinsed.
- the towel dry strands are treated with solution (2) (permanent fixation) and allowed to stand for 10 min. Then the strands are rinsed under tap water and dried for 12 hours at room temperature.
- Test 3 A colouring material consisting of the compound of formula (102) in plantaren is applied on dry hair and then allowed to stand for 20 min., rinsed and dried for 12 hours at room temperature.
- a solution 1 (pH 8.2; permanent lotion) is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 10 min. Then the strands are rinsed under tap water and the towel dry strands are treated with a colouring material solution consisting of a compound of formula (102) according to example A2, in plantaren and allowed to stand for 20 min and then rinsed. Then, the towel dry strands are treated with a solution 2 (permanent fixation), and allowed to stand for 10 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- Application Example 56 is repeated with the difference that instead of a compound of formula (102) a compound of formula (106) is used.
- Hair (two blond, two middle blond and two damaged hair strands) is treated with a colouring material solution consisting of a 0.1%, b.w. colouring material solution of a compound of formula (102) according to example A2, in plantaren and allowed to stand for 20 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- 0.05g of a 0.1% b.w. solution of ammoniumthioglycolate in water having a pH of 8.0 (the pH is adjusted by ammonia and citric acid), is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 20 min. Then, the hair is rinsed under tap water, and the towel dry strands are treated with a fixating solution (Goldwell) having a pH 3.92 and allowed to stand for 10 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- a fixating solution Goldwell
- Hair (two blond, two middle blond and two damaged hair strands) is treated with a colouring material solution consisting of a 0.1%, b.w. colouring material solution of a compound of formula (102), in plantaren and allowed to stand for 20 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- a colouring material solution consisting of a 0.1%, b.w. colouring material solution of a compound of formula (102), in plantaren and allowed to stand for 20 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- a solution 4 (permanent lotion) having a pH 8.7, is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 15 min. Then, the strands are rinsed under tap water, and the towel dry strands are treated with a colouring material consisting of a 0.1%, b.w. solution of compound of formula (101) in plantaren and allowed to stand for 20 min. and then rinsed. Then, the towel dry strands are treated with a solution 5 (permanent fixation), and allowed to stand for 10 min. Then the strands are rinsed under tap water and dried 12 hours at room temperature.
- Hair (two blond, two middle blond and two damaged hair strands) is treated with a colouring material solution consisting of a 0.1%, b.w. solution of compound of formula (107) in plantaren, and allowed to stand for 20 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- a colouring material solution consisting of a 0.1%, b.w. solution of compound of formula (107) in plantaren, and allowed to stand for 20 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- a solution 1 (permanent lotion), having a pH 8.2, is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 15 min.. Then the strands are rinsed under tap water, and the towel dry strands are treated with a colouring material consisting of a 0.1% b.w. solution of compound of formula (101) in plantaren and allowed to stand for 20 min. and then rinsed. Then, the towel dry strands are treated with a solution 2 (permanent fixation), and allowed to stand for 10 min. Then, the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- the strands are rinsed under tap water and dried 12 hours at room temperature.
- composition comprising
- a solution 4 (permanent lotion) having a pH 8.7, is applied on shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 15 min. Then, the strands are rinsed under tap water, and the towel dry strands are treated with a colouring material consisting of a 0.1%, b.w. solution of compound of formula (101) according to example A1 , in water and allowed to stand for 20 min. and then rinsed. Then, the towel dry strands are treated with a solution 5 (permanent fixation), and allowed to stand for 10 min.
- the strands are rinsed under tap water, and then shampooed.
- a solution 4 permanent lotion having a pH 8.7, is applied on the shampooed hair (two blond, two middle blond and two damaged hair strands) and allowed to stand for 15 min. Then, the strands are rinsed under tap water, and the towel dry strands are treated with a colouring material comprising
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Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXPA06011502A MXPA06011502A (en) | 2004-04-08 | 2005-03-29 | Disulfide dyes, composition comprising them and method of dyeing hair. |
KR1020067022193A KR101232694B1 (en) | 2004-04-08 | 2005-03-29 | Disulfide dyes, composition comprising them and method of dyeing hair |
JP2007506763A JP5274832B2 (en) | 2004-04-08 | 2005-03-29 | Disulfide dye, composition containing the same and method for dyeing hair |
CN2005800188700A CN1997340B (en) | 2004-04-08 | 2005-03-29 | Disulfide dyes, composition comprising them and method of dyeing |
EP05729805A EP1750663A2 (en) | 2004-04-08 | 2005-03-29 | Disulfide dyes, composition comprising them and method of dyeing hair |
BRPI0508391-5A BRPI0508391B1 (en) | 2004-04-08 | 2005-03-29 | Method of dyeing fibers containing keratin, and composition |
US11/547,571 US7476260B2 (en) | 2004-04-08 | 2005-03-29 | Disulfide dyes, composition comprising them and method of dyeing hair |
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EP04101455.6 | 2004-04-08 | ||
EP04101455 | 2004-04-08 | ||
EP04105995.7 | 2004-11-23 | ||
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US (1) | US7476260B2 (en) |
EP (2) | EP1750663A2 (en) |
JP (1) | JP5274832B2 (en) |
KR (1) | KR101232694B1 (en) |
CN (1) | CN1997340B (en) |
AR (1) | AR048595A1 (en) |
BR (1) | BRPI0508391B1 (en) |
ES (1) | ES2439708T3 (en) |
GB (1) | GB2412916A (en) |
MX (1) | MXPA06011502A (en) |
TW (1) | TW200613457A (en) |
WO (1) | WO2005097051A2 (en) |
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JP2006111626A (en) * | 2004-10-14 | 2006-04-27 | L'oreal Sa | Dyeing composition containing specific disulfide dye and method for dyeing human keratin fiber therewith |
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JP5274832B2 (en) | 2013-08-28 |
EP2075036A1 (en) | 2009-07-01 |
KR20070006859A (en) | 2007-01-11 |
GB0506757D0 (en) | 2005-05-11 |
TW200613457A (en) | 2006-05-01 |
AR048595A1 (en) | 2006-05-10 |
US7476260B2 (en) | 2009-01-13 |
US20080295260A1 (en) | 2008-12-04 |
EP2075036B1 (en) | 2013-11-06 |
CN1997340A (en) | 2007-07-11 |
EP1750663A2 (en) | 2007-02-14 |
BRPI0508391B1 (en) | 2017-10-10 |
GB2412916A (en) | 2005-10-12 |
BRPI0508391A (en) | 2007-09-25 |
KR101232694B1 (en) | 2013-02-13 |
CN1997340B (en) | 2013-07-17 |
JP2007532513A (en) | 2007-11-15 |
WO2005097051A3 (en) | 2005-12-15 |
MXPA06011502A (en) | 2006-12-15 |
ES2439708T3 (en) | 2014-01-24 |
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