WO2005054495A3 - Ligand-containing micelles and uses thereof - Google Patents
Ligand-containing micelles and uses thereof Download PDFInfo
- Publication number
- WO2005054495A3 WO2005054495A3 PCT/US2004/039452 US2004039452W WO2005054495A3 WO 2005054495 A3 WO2005054495 A3 WO 2005054495A3 US 2004039452 W US2004039452 W US 2004039452W WO 2005054495 A3 WO2005054495 A3 WO 2005054495A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ligand
- containing micelles
- micelles
- kits
- preparation
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04812053A EP1687635A2 (en) | 2003-11-26 | 2004-11-24 | Ligand-containing micelles and uses thereof |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52549203P | 2003-11-26 | 2003-11-26 | |
US60/525,492 | 2003-11-26 | ||
US62850904P | 2004-11-15 | 2004-11-15 | |
US60/628,509 | 2004-11-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005054495A2 WO2005054495A2 (en) | 2005-06-16 |
WO2005054495A3 true WO2005054495A3 (en) | 2005-08-04 |
Family
ID=34657184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/039452 WO2005054495A2 (en) | 2003-11-26 | 2004-11-24 | Ligand-containing micelles and uses thereof |
Country Status (3)
Country | Link |
---|---|
US (2) | US20050244891A1 (en) |
EP (1) | EP1687635A2 (en) |
WO (1) | WO2005054495A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003270554A1 (en) * | 2002-09-09 | 2004-03-29 | Applera Corporation | Fluorescent enzyme assay methods and compositions |
US20050239217A1 (en) * | 2003-11-26 | 2005-10-27 | Applera Corporation | Fluorogenic homogeneous binding assay methods and compositions |
WO2005059163A2 (en) * | 2003-12-15 | 2005-06-30 | Applera Corporation | Methods, compositions, and kits for analysis of enzyme activity in cells |
US7304146B2 (en) * | 2004-01-16 | 2007-12-04 | Applera Corporation | Fluorogenic kinase assays and substrates |
US10858384B2 (en) | 2004-03-22 | 2020-12-08 | Kode Biotech Limited | Synthetic molecule constructs |
WO2006002221A2 (en) * | 2004-06-21 | 2006-01-05 | Applera Corporation | Fluorogenic enzyme assays and substrates for kinases and phosphatases |
US20060035302A1 (en) * | 2004-06-21 | 2006-02-16 | Applera Corporation | Kinase substrates with multiple phosphorylation sites |
US20060121553A1 (en) * | 2004-10-29 | 2006-06-08 | Applera Corporation | Fluorogenic enzyme assay methods, kits and compositions using charge-balancers |
JP2008526207A (en) * | 2004-12-30 | 2008-07-24 | アプレラ コーポレイション | Compositions, methods and kits for real-time enzyme assays using charged molecules |
SE533176C2 (en) * | 2007-07-12 | 2010-07-13 | Euro Diagnostica Ab | Antigen Exposing Micell |
WO2009111439A2 (en) | 2008-03-04 | 2009-09-11 | The Trustees Of The University Of Pennsylvania | In vivo detection of phospholipase activation |
US9238811B2 (en) * | 2009-07-14 | 2016-01-19 | Northeastern University | siRNA phospholipid conjugate |
US10240180B2 (en) * | 2011-02-01 | 2019-03-26 | The Regents Of The University Of California | Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry |
US20140336071A1 (en) * | 2011-09-29 | 2014-11-13 | Emory University | Devices, compositions, and methods for measuring molecules and forces |
IT201700086879A1 (en) * | 2017-07-28 | 2019-01-28 | Univ Degli Studi Cagliari | DOUBLE LAYER LIPID GRAPE VARIETIES CONTAINING ADRENALIN, FOR USE IN TREATMENT OF CARDIAC EMERGENCIES |
US20210244664A1 (en) * | 2018-06-27 | 2021-08-12 | Breath Therapeutics Gmbh | Pharmaceutical compositions in lyophilized form |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5210040A (en) * | 1987-07-29 | 1993-05-11 | Abbott Laboratories | Process for coupling antibodies or antibody fragments to liposomes |
US5366895A (en) * | 1990-03-05 | 1994-11-22 | Becton, Dickinson And Company | Method for lysing liposomes using polyethyleneglycol monononylphenyl ethers |
US6235535B1 (en) * | 1996-06-28 | 2001-05-22 | Valtion Teknillinen Tutkimuskeskus | Fluorescent energy transfer ligand interaction assay on a lipid film |
US20030135869A1 (en) * | 2000-10-10 | 2003-07-17 | Steven Farber | High throughput genetic screening of lipid and cholesterol processing using fluorescent compounds |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089392A (en) * | 1990-03-30 | 1992-02-18 | The United States Of America As Represented By Of The Department Of Health And Human Services | Fluorogenic substrates for measurement of lysosomal enzyme activities within intact cells |
US5958713A (en) * | 1995-01-31 | 1999-09-28 | Novo Nordisk A/S | Method of detecting biologically active substances by using green fluorescent protein |
US5925558A (en) * | 1996-07-16 | 1999-07-20 | The Regents Of The University Of California | Assays for protein kinases using fluorescent protein substrates |
US5912137A (en) * | 1996-07-16 | 1999-06-15 | The Regents Of The University Of California | Assays for protein kinases using fluorescent |
US6087325A (en) * | 1996-10-15 | 2000-07-11 | The Liposome Company, Inc. | Peptide-lipid conjugates |
US6339069B1 (en) * | 1996-10-15 | 2002-01-15 | Elan Pharmaceuticalstechnologies, Inc. | Peptide-lipid conjugates, liposomes and lipsomal drug delivery |
US6037137A (en) * | 1997-02-20 | 2000-03-14 | Oncoimmunin, Inc. | Fluorogenic peptides for the detection of protease activity |
US6498005B1 (en) * | 1998-09-30 | 2002-12-24 | Caliper Technologies Corp. | Homogeneous assay methods |
JP2004500859A (en) * | 2000-05-31 | 2004-01-15 | プロメガ コーポレイション | Evaluation assays for kinases and phosphatases |
US7049080B2 (en) * | 2000-08-11 | 2006-05-23 | Joachim Kramer | Process for detecting serine/threonine kinase activity |
AU2003270554A1 (en) * | 2002-09-09 | 2004-03-29 | Applera Corporation | Fluorescent enzyme assay methods and compositions |
US20050239217A1 (en) * | 2003-11-26 | 2005-10-27 | Applera Corporation | Fluorogenic homogeneous binding assay methods and compositions |
WO2005059163A2 (en) * | 2003-12-15 | 2005-06-30 | Applera Corporation | Methods, compositions, and kits for analysis of enzyme activity in cells |
US7304146B2 (en) * | 2004-01-16 | 2007-12-04 | Applera Corporation | Fluorogenic kinase assays and substrates |
US20060003383A1 (en) * | 2004-06-07 | 2006-01-05 | Applera Corporation | Fluorogenic enzyme activity assay methods and compositions using fragmentable linkers |
US20060035302A1 (en) * | 2004-06-21 | 2006-02-16 | Applera Corporation | Kinase substrates with multiple phosphorylation sites |
-
2004
- 2004-11-24 EP EP04812053A patent/EP1687635A2/en not_active Withdrawn
- 2004-11-24 WO PCT/US2004/039452 patent/WO2005054495A2/en not_active Application Discontinuation
- 2004-11-24 US US10/997,066 patent/US20050244891A1/en not_active Abandoned
-
2009
- 2009-05-20 US US12/469,597 patent/US20100112619A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5210040A (en) * | 1987-07-29 | 1993-05-11 | Abbott Laboratories | Process for coupling antibodies or antibody fragments to liposomes |
US5366895A (en) * | 1990-03-05 | 1994-11-22 | Becton, Dickinson And Company | Method for lysing liposomes using polyethyleneglycol monononylphenyl ethers |
US6235535B1 (en) * | 1996-06-28 | 2001-05-22 | Valtion Teknillinen Tutkimuskeskus | Fluorescent energy transfer ligand interaction assay on a lipid film |
US20030135869A1 (en) * | 2000-10-10 | 2003-07-17 | Steven Farber | High throughput genetic screening of lipid and cholesterol processing using fluorescent compounds |
Non-Patent Citations (1)
Title |
---|
SUN HONGYE ET AL: "Real-time protein kinase assay.", ANALYTICAL CHEMISTRY. 1 APR 2005, vol. 77, no. 7, 1 April 2005 (2005-04-01), pages 2043 - 2049, XP002329236, ISSN: 0003-2700 * |
Also Published As
Publication number | Publication date |
---|---|
EP1687635A2 (en) | 2006-08-09 |
WO2005054495A2 (en) | 2005-06-16 |
US20050244891A1 (en) | 2005-11-03 |
US20100112619A1 (en) | 2010-05-06 |
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