WO2005051995A3 - Novel advanced glycosylation end product-specific receptor-like protein and nucleic acids encoding same - Google Patents
Novel advanced glycosylation end product-specific receptor-like protein and nucleic acids encoding same Download PDFInfo
- Publication number
- WO2005051995A3 WO2005051995A3 PCT/US2004/038870 US2004038870W WO2005051995A3 WO 2005051995 A3 WO2005051995 A3 WO 2005051995A3 US 2004038870 W US2004038870 W US 2004038870W WO 2005051995 A3 WO2005051995 A3 WO 2005051995A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acids
- end product
- specific receptor
- protein
- advanced glycosylation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52426603P | 2003-11-19 | 2003-11-19 | |
US60/524,266 | 2003-11-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005051995A2 WO2005051995A2 (en) | 2005-06-09 |
WO2005051995A3 true WO2005051995A3 (en) | 2005-08-25 |
Family
ID=34632883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/038870 WO2005051995A2 (en) | 2003-11-19 | 2004-11-19 | Novel advanced glycosylation end product-specific receptor-like protein and nucleic acids encoding same |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005051995A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8877192B2 (en) | 2004-08-03 | 2014-11-04 | Transtech Pharma, Llc | Rage fusion proteins and methods of use |
US9034341B2 (en) | 2009-04-20 | 2015-05-19 | Transtech Pharma, Llc | Control of RAGE fusion protein glycosylation and RAGE fusion protein compositions |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1771565B1 (en) | 2004-07-20 | 2012-09-05 | The Feinstein Institute for Medical Research | Rage protein derivatives |
US20070087406A1 (en) * | 2005-05-04 | 2007-04-19 | Pei Jin | Isoforms of receptor for advanced glycation end products (RAGE) and methods of identifying and using same |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997039121A1 (en) * | 1996-04-16 | 1997-10-23 | Schering Aktiengesellschaft | Advanced glycosylation end-product receptor peptides and uses therefor |
WO2000020458A1 (en) * | 1998-10-05 | 2000-04-13 | The Trustees Of Columbia University In The City Of New York | Methods for determining whether a compound is capable of inhibiting the interaction of a peptide with rage |
WO2001092892A2 (en) * | 2000-05-30 | 2001-12-06 | Transtech Pharma, Inc. | Methods to identify compounds that modulate rage |
WO2002030889A2 (en) * | 2000-10-13 | 2002-04-18 | The Trustees Of Columbia University In The City Of New York | A method for inhibiting new tissue growth in blood vessels in a patient subjected to blood vessel injury |
WO2002059260A2 (en) * | 2000-11-17 | 2002-08-01 | Hyseq, Inc. | Nucleic acids and polypeptides |
-
2004
- 2004-11-19 WO PCT/US2004/038870 patent/WO2005051995A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997039121A1 (en) * | 1996-04-16 | 1997-10-23 | Schering Aktiengesellschaft | Advanced glycosylation end-product receptor peptides and uses therefor |
WO2000020458A1 (en) * | 1998-10-05 | 2000-04-13 | The Trustees Of Columbia University In The City Of New York | Methods for determining whether a compound is capable of inhibiting the interaction of a peptide with rage |
WO2001092892A2 (en) * | 2000-05-30 | 2001-12-06 | Transtech Pharma, Inc. | Methods to identify compounds that modulate rage |
WO2002030889A2 (en) * | 2000-10-13 | 2002-04-18 | The Trustees Of Columbia University In The City Of New York | A method for inhibiting new tissue growth in blood vessels in a patient subjected to blood vessel injury |
WO2002059260A2 (en) * | 2000-11-17 | 2002-08-01 | Hyseq, Inc. | Nucleic acids and polypeptides |
Non-Patent Citations (2)
Title |
---|
KISLINGER T ET AL: "N-epsilon-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 274, no. 44, 29 October 1999 (1999-10-29), pages 31740 - 31749, XP002217809, ISSN: 0021-9258 * |
SCHMIDT A M ET AL: "ACTIVATION OF RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS A MECHANISM FOR CHRONIC VASCULAR DYSFUNCTION IN DIABETIC VASCULOPATHY AND ATHEROSCLEROSIS", CIRCULATION RESEARCH, GRUNE AND STRATTON, BALTIMORE, US, vol. 84, 19 March 1999 (1999-03-19), pages 489 - 497, XP002909514, ISSN: 0009-7330 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8877192B2 (en) | 2004-08-03 | 2014-11-04 | Transtech Pharma, Llc | Rage fusion proteins and methods of use |
US9034341B2 (en) | 2009-04-20 | 2015-05-19 | Transtech Pharma, Llc | Control of RAGE fusion protein glycosylation and RAGE fusion protein compositions |
Also Published As
Publication number | Publication date |
---|---|
WO2005051995A2 (en) | 2005-06-09 |
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