WO2005050563A3 - Pathological tissue mapping - Google Patents

Pathological tissue mapping

Info

Publication number
WO2005050563A3
WO2005050563A3 PCT/US2004/038536 US2004038536W WO2005050563A3 WO 2005050563 A3 WO2005050563 A3 WO 2005050563A3 US 2004038536 W US2004038536 W US 2004038536W WO 2005050563 A3 WO2005050563 A3 WO 2005050563A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
tissue
pathological
objects
measurement
results
Prior art date
Application number
PCT/US2004/038536
Other languages
French (fr)
Other versions
WO2005050563A2 (en )
Inventor
Angeliki Kotsianti
Olivier Saidi
Mikhail Teverovskiy
Original Assignee
Aureon Biosciences Corp
Angeliki Kotsianti
Olivier Saidi
Mikhail Teverovskiy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06KRECOGNITION OF DATA; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K9/00Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
    • G06K9/00127Acquiring and recognising microscopic objects, e.g. biological cells and cellular parts
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/11Region-based segmentation
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/155Segmentation; Edge detection involving morphological operators
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/187Segmentation; Edge detection involving region growing; involving region merging; involving connected component labelling
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • G06T7/62Analysis of geometric attributes of area, perimeter, diameter or volume
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20036Morphological image processing
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30056Liver; Hepatic
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30061Lung

Abstract

Embodiments of the present invention are directed to quantitative analysis of tissues enabling the measurement of objects and parameters of objects found in images of tissues including perimeter, area, and other metrics of such objects. Measurement results may be input into a relational database where they can be statistically analyzed and compared across studies. The measurement results may be used to create a pathological tissue map of a tissue image, to allow a pathologist to determine a pathological condition of the imaged tissue more quickly.
PCT/US2004/038536 2003-11-17 2004-11-17 Pathological tissue mapping WO2005050563A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US52081503 true 2003-11-17 2003-11-17
US60/520,815 2003-11-17

Publications (2)

Publication Number Publication Date
WO2005050563A2 true WO2005050563A2 (en) 2005-06-02
WO2005050563A3 true true WO2005050563A3 (en) 2006-03-09

Family

ID=34619517

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/038536 WO2005050563A3 (en) 2003-11-17 2004-11-17 Pathological tissue mapping

Country Status (2)

Country Link
US (2) US7483554B2 (en)
WO (1) WO2005050563A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114615B2 (en) 2006-05-17 2012-02-14 Cernostics, Inc. Method for automated tissue analysis

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005086068A3 (en) * 2004-02-27 2006-10-12 Aureon Lab Inc Methods and systems for predicting occurrence of an event
US7490009B2 (en) * 2004-08-03 2009-02-10 Fei Company Method and system for spectroscopic data analysis
US7672916B2 (en) * 2005-08-16 2010-03-02 The Trustees Of Columbia University In The City Of New York Methods, systems, and media for music classification
US7599893B2 (en) * 2005-10-13 2009-10-06 Aureon Laboratories, Inc. Methods and systems for feature selection in machine learning based on feature contribution and model fitness
GB0605358D0 (en) * 2006-03-09 2006-04-26 Cytokinetics Inc Cellular Predictive Models For Toxiciltles
GB0605351D0 (en) * 2006-03-09 2006-04-26 Cytokinetics Inc Cellular Predictive Models For Toxicities
GB0605362D0 (en) * 2006-03-09 2006-04-26 Cytokinetics Inc Cellular predictive models for toxicities
JP2009540272A (en) * 2006-06-05 2009-11-19 ヒューマニタス・ミラソーレ・エス.ピー.エー. In vitro diagnostic method of diseases that affect the human or animal tissue
CN103823995B (en) * 2006-08-01 2018-04-10 皇家飞利浦电子股份有限公司 Adaptive biological treatment program to develop guidance
US20080032321A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and methods for analyzing images of tissue samples
US8131476B2 (en) * 2006-08-07 2012-03-06 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US8060348B2 (en) * 2006-08-07 2011-11-15 General Electric Company Systems for analyzing tissue samples
GB2451416B (en) * 2006-09-07 2010-05-19 Siemens Molecular Imaging Ltd ROI-based assessment of abnormality using transformation invariant features
US9070006B2 (en) 2006-12-19 2015-06-30 Hologic, Inc. Method and system for processing an image of a biological specimen
US20080248478A1 (en) * 2007-02-02 2008-10-09 Jochen Renzing Molecular histological analysis of multicellular samples
EP1953662A1 (en) 2007-02-02 2008-08-06 Boehringer Mannheim Gmbh Molecular histology
US20080187194A1 (en) * 2007-02-05 2008-08-07 Zhang Daoxian H Cad image normalization
JP4895204B2 (en) * 2007-03-22 2012-03-14 富士フイルム株式会社 Image component separation apparatus, method and program, and the normal image generation apparatus, method, and program
US20100129292A1 (en) * 2007-04-11 2010-05-27 Oregon Health & Science University Method and apparatus for noninvasive quantitative detection of fibrosis in the heart
US7949181B2 (en) * 2007-06-28 2011-05-24 General Electric Company Segmentation of tissue images using color and texture
US8139831B2 (en) * 2007-12-06 2012-03-20 Siemens Aktiengesellschaft System and method for unsupervised detection and gleason grading of prostate cancer whole mounts using NIR fluorscence
JP5365011B2 (en) * 2008-01-29 2013-12-11 日本電気株式会社 Pathological diagnosis support device, pathological diagnosis support method, and program
WO2010011356A3 (en) * 2008-07-25 2010-04-08 Aureon Laboratories, Inc. Systems and methods of treating, diagnosing and predicting the occurrence of a medical condition
US20130080134A1 (en) * 2008-07-25 2013-03-28 Fundação D. Anna Sommer Champalimaud e Dr. Carlos Montez Champalimaud Systems and methods for predicting favorable-risk disease for patients enrolled in active surveillance
US9779213B2 (en) 2008-07-25 2017-10-03 Fundacao D. Anna Sommer Champalimaud E Dr. Carlos Montez Champalimaud System for evaluating a pathological stage of prostate cancer
CN103488870A (en) * 2008-08-15 2014-01-01 皇家飞利浦电子股份有限公司 Model enhanced imaging
JP5648479B2 (en) * 2008-10-09 2015-01-07 日本電気株式会社 Histopathological diagnosis support system, pathological diagnosis support program, histopathological diagnosis support method
WO2010103389A1 (en) 2009-03-11 2010-09-16 Sensovation Ag Autofocus method and autofocus device
JP2010220908A (en) * 2009-03-25 2010-10-07 Sony Corp Image processor, image processing method, and program
EP2425401A2 (en) 2009-04-28 2012-03-07 Koninklijke Philips Electronics N.V. Microdissection method and information processing system
WO2010136942A3 (en) * 2009-05-28 2011-04-07 Koninklijke Philips Electronics N.V. A method and device for side-effect prognosis and monitoring
JP5387146B2 (en) * 2009-06-03 2014-01-15 日本電気株式会社 Pathological tissue image analyzing apparatus, pathological tissue image analysis method, histopathological image analysis program
US20110064289A1 (en) * 2009-09-14 2011-03-17 Siemens Medical Solutions Usa, Inc. Systems and Methods for Multilevel Nodule Attachment Classification in 3D CT Lung Images
US8724866B2 (en) * 2009-09-14 2014-05-13 Siemens Medical Solutions Usa, Inc. Multi-level contextual learning of data
US8269827B2 (en) * 2009-09-29 2012-09-18 General Electric Company System and methods for mapping fluorescent images into a bright field color space
CA2842721C (en) 2009-10-19 2016-03-29 Ventana Medical Systems, Inc. Imaging system and techniques
US9036883B2 (en) * 2011-01-10 2015-05-19 The Regents Of The University Of Michigan System and methods for detecting liver disease
EP2506173A1 (en) * 2011-03-28 2012-10-03 Canon Kabushiki Kaisha Medical diagnosis support apparatus and medical diagnosis support method
JP5997256B2 (en) 2011-04-15 2016-09-28 コンスティテューション・メディカル・インコーポレイテッドConstitution Medical, Inc. Measurements of volume and components of the cell
US9459196B2 (en) 2011-07-22 2016-10-04 Roche Diagnostics Hematology, Inc. Blood analyzer calibration and assessment
EP2734828A1 (en) 2011-07-22 2014-05-28 Roche Diagnostics Hematology, Inc. Identifying and measuring reticulocytes
WO2013022688A1 (en) * 2011-08-05 2013-02-14 Siemens Healthcare Diagnostics Inc. Automated detection of diagnostically relevant regions in pathology images
US8639013B2 (en) 2011-08-17 2014-01-28 General Electric Company System and methods for generating a brightfield image using fluorescent images
US20140193052A1 (en) * 2011-08-23 2014-07-10 Yoshiko Yoshihara Information processing system, information processing method, information processing apparatus, control method thereof and control program
CN103814395A (en) * 2011-09-19 2014-05-21 皇家飞利浦有限公司 Adapting x-ray slave image to x-ray master image
US20140233826A1 (en) * 2011-09-27 2014-08-21 Board Of Regents Of The University Of Texas System Systems and methods for automated screening and prognosis of cancer from whole-slide biopsy images
JP5771513B2 (en) * 2011-11-24 2015-09-02 学校法人慶應義塾 Pathological diagnosis support device, pathological diagnosis support method, and pathological diagnosis support program
JP5953035B2 (en) * 2011-11-28 2016-07-13 学校法人慶應義塾 Pathological diagnosis support device, pathological diagnosis support method, and pathological diagnosis support program
EP2847738B1 (en) * 2012-05-11 2017-07-12 Dako Denmark A/S Method and apparatus for image scoring and analysis
US8664595B2 (en) 2012-06-28 2014-03-04 Fei Company Cluster analysis of unknowns in SEM-EDS dataset
US9188555B2 (en) 2012-07-30 2015-11-17 Fei Company Automated EDS standards calibration
US9123120B2 (en) * 2012-08-24 2015-09-01 DR Vision Technologies LLC Progressive decision for cellular process selection
US9778215B2 (en) 2012-10-26 2017-10-03 Fei Company Automated mineral classification
US9048067B2 (en) 2012-10-26 2015-06-02 Fei Company Mineral identification using sequential decomposition into elements from mineral definitions
US8937282B2 (en) 2012-10-26 2015-01-20 Fei Company Mineral identification using mineral definitions including variability
US9091635B2 (en) 2012-10-26 2015-07-28 Fei Company Mineral identification using mineral definitions having compositional ranges
US9194829B2 (en) 2012-12-28 2015-11-24 Fei Company Process for performing automated mineralogy
WO2014144234A1 (en) * 2013-03-15 2014-09-18 Sony Corporation Combining information of different levels for content-based retrieval of digital pathology images
EP3003159A4 (en) * 2013-05-24 2017-03-15 Sunnybrook Res Inst System and method for classifying and characterizing tissues using first-order and second-order statistics of quantitative ultrasound parametric maps
JP2015038467A (en) * 2013-07-18 2015-02-26 パナソニックIpマネジメント株式会社 Pathological diagnosis support apparatus and pathological diagnosis support method
US9784665B1 (en) * 2014-12-29 2017-10-10 Flagship Biosciences, Inc. Methods for quantitative assessment of muscle fibers in muscular dystrophy
WO2016134474A1 (en) * 2015-02-25 2016-09-01 London Health Sciences Centre Research Inc. Automated segmentation of histological sections for vasculature quantification
US20180114317A1 (en) * 2016-10-21 2018-04-26 Nantomics, Llc Digital histopathology and microdissection

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells
US5016283A (en) * 1985-11-04 1991-05-14 Cell Analysis Systems, Inc. Methods and apparatus for immunoploidy analysis
WO1996009594A1 (en) * 1994-09-20 1996-03-28 Neopath, Inc. Apparatus for automated identification of thick cell groupings on a biological specimen
US5526258A (en) * 1990-10-10 1996-06-11 Cell Analysis System, Inc. Method and apparatus for automated analysis of biological specimens
US6137899A (en) * 1994-09-20 2000-10-24 Tri Path Imaging, Inc. Apparatus for the identification of free-lying cells

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307030B1 (en) * 1988-04-15 2001-10-23 The University Of North Carolina At Chapel Hill Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions
US6025128A (en) * 1994-09-29 2000-02-15 The University Of Tulsa Prediction of prostate cancer progression by analysis of selected predictive parameters
WO1996012187A1 (en) * 1994-10-13 1996-04-25 Horus Therapeutics, Inc. Computer assisted methods for diagnosing diseases
KR0154739B1 (en) * 1995-04-19 1998-11-16 김광호 Fractal image compression device and method
US6063026A (en) * 1995-12-07 2000-05-16 Carbon Based Corporation Medical diagnostic analysis system
US7245748B2 (en) * 1997-01-21 2007-07-17 Yeda Research And Development Co., Ltd. Apparatus for monitoring a system with time in space and method for diagnosing a condition of a prostate
US6259724B1 (en) * 1996-10-18 2001-07-10 Telefonaktiebolaget L M Ericsson (Publ) Random access in a mobile telecommunications system
US6059724A (en) 1997-02-14 2000-05-09 Biosignal, Inc. System for predicting future health
US6063028A (en) * 1997-03-20 2000-05-16 Luciano; Joanne Sylvia Automated treatment selection method
US6409664B1 (en) * 1997-07-01 2002-06-25 Michael W. Kattan Nomograms to aid in the treatment of prostatic cancer
US6545139B1 (en) * 1998-03-13 2003-04-08 Baylor College Of Medicine DNA sequence encoding the p99 gene and kits for the detection of neoplasia
US6789069B1 (en) * 1998-05-01 2004-09-07 Biowulf Technologies Llc Method for enhancing knowledge discovered from biological data using a learning machine
US7117188B2 (en) * 1998-05-01 2006-10-03 Health Discovery Corporation Methods of identifying patterns in biological systems and uses thereof
US6996549B2 (en) * 1998-05-01 2006-02-07 Health Discovery Corporation Computer-aided image analysis
US6658395B1 (en) * 1998-05-01 2003-12-02 Biowulf Technologies, L.L.C. Enhancing knowledge discovery from multiple data sets using multiple support vector machines
US6128608A (en) * 1998-05-01 2000-10-03 Barnhill Technologies, Llc Enhancing knowledge discovery using multiple support vector machines
US6413533B1 (en) * 1998-05-07 2002-07-02 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
US6410043B1 (en) * 1998-05-07 2002-06-25 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
US6699714B1 (en) * 1998-07-17 2004-03-02 University Of Rochester Androgen receptor coactivators
US6472415B1 (en) * 1998-12-18 2002-10-29 Biophysica, Inc. Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
US6828429B1 (en) * 1999-03-26 2004-12-07 Henry M. Jackson Foundation For The Advancement Of Military Medicine Prostate-specific gene, PCGEM1, and the methods of using PCGEM1 to detect, treat, and prevent prostate cancer
JP2002542793A (en) * 1999-04-22 2002-12-17 ザ アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ Assay of gene expression patterns by Multi fluorescent fish
US6611833B1 (en) * 1999-06-23 2003-08-26 Tissueinformatics, Inc. Methods for profiling and classifying tissue using a database that includes indices representative of a tissue population
US6993170B2 (en) * 1999-06-23 2006-01-31 Icoria, Inc. Method for quantitative analysis of blood vessel structure
US7151100B1 (en) * 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) * 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7129262B2 (en) * 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7361680B2 (en) * 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US20040224306A1 (en) * 1999-11-30 2004-11-11 Frederich-Wilhelm Kuhne Evaluating and predicting clinical outcomes by gene expression analysis
US6451683B1 (en) * 2000-08-28 2002-09-17 Micron Technology, Inc. Damascene structure and method of making
US7393921B2 (en) * 2000-12-04 2008-07-01 Institute For Systems Biology Prostate-specific polypeptide pamp and encoding nucleic acid molecules
US6944602B2 (en) * 2001-03-01 2005-09-13 Health Discovery Corporation Spectral kernels for learning machines
US20030048931A1 (en) 2001-03-23 2003-03-13 Peter Johnson Quantification and differentiation of tissue based upon quantitative image analysis
US7071303B2 (en) * 2001-03-28 2006-07-04 Institute For Systems Biology Androgen regulated prostate specific nucleic acids
US7353215B2 (en) * 2001-05-07 2008-04-01 Health Discovery Corporation Kernels and methods for selecting kernels for use in learning machines
WO2002097716A1 (en) * 2001-05-29 2002-12-05 Tissueinformatics, Inc. Robust stain detection and quantification for histological specimens based on a physical model for stain absorption
US7332290B2 (en) * 2001-08-02 2008-02-19 The Regents Of The University Of Michigan Dectection of AMACR cancer markers in urine
US7229774B2 (en) * 2001-08-02 2007-06-12 Regents Of The University Of Michigan Expression profile of prostate cancer
US6949342B2 (en) * 2001-12-21 2005-09-27 Whitehead Institute For Biomedical Research Prostate cancer diagnosis and outcome prediction by expression analysis
US20030235816A1 (en) * 2002-03-14 2003-12-25 Baylor College Of Medicine (By Slawin And Shariat) Method to determine outcome for patients with prostatic disease
WO2004026116A3 (en) * 2002-09-19 2004-07-01 Dennis A Carson Use of etodoclac to treat hyperplasia
WO2004071572A3 (en) * 2003-02-06 2005-01-13 David Agus Gene expression markers for response to egfr inhibitor drugs
JP2006522340A (en) * 2003-04-02 2006-09-28 メルク エンド カムパニー インコーポレーテッドMerck & Company Incoporated Analysis of mass spectrometry data
US7309867B2 (en) * 2003-04-18 2007-12-18 Medispectra, Inc. Methods and apparatus for characterization of tissue samples
WO2005086068A3 (en) * 2004-02-27 2006-10-12 Aureon Lab Inc Methods and systems for predicting occurrence of an event

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells
US5016283A (en) * 1985-11-04 1991-05-14 Cell Analysis Systems, Inc. Methods and apparatus for immunoploidy analysis
US5526258A (en) * 1990-10-10 1996-06-11 Cell Analysis System, Inc. Method and apparatus for automated analysis of biological specimens
WO1996009594A1 (en) * 1994-09-20 1996-03-28 Neopath, Inc. Apparatus for automated identification of thick cell groupings on a biological specimen
US6137899A (en) * 1994-09-20 2000-10-24 Tri Path Imaging, Inc. Apparatus for the identification of free-lying cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EGMONT-PETERSEN M ET AL: "Image processing with neural networks-a review", PATTERN RECOGNITION, ELSEVIER, KIDLINGTON, GB, vol. 35, no. 10, October 2002 (2002-10-01), pages 2279 - 2301, XP004366785, ISSN: 0031-3203 *
SCHOELKOPF B ET AL: "COMPARING SUPPORT VECTOR MACHINES WITH GAUSSIAN KERNELS TO RADIAL BASIS FUNCTION CLASSIFIERS", IEEE TRANSACTIONS ON SIGNAL PROCESSING, IEEE SERVICE CENTER, NEW YORK, NY, US, vol. 45, no. 11, November 1997 (1997-11-01), pages 2758 - 2765, XP001133714, ISSN: 1053-587X *
YEH W-C ET AL: "Liver fibrosis grade classification with B-mode ultrasound", ULTRASOUND IN MEDICINE AND BIOLOGY, NEW YORK, NY, US, vol. 29, no. 9, September 2003 (2003-09-01), pages 1229 - 1235, XP004463701, ISSN: 0301-5629 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114615B2 (en) 2006-05-17 2012-02-14 Cernostics, Inc. Method for automated tissue analysis
US8597899B2 (en) 2006-05-17 2013-12-03 Cernostics, Inc. Method for automated tissue analysis

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Publication number Publication date Type
US20090262993A1 (en) 2009-10-22 application
WO2005050563A2 (en) 2005-06-02 application
US7483554B2 (en) 2009-01-27 grant
US20050165290A1 (en) 2005-07-28 application

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