WO2005046765A2 - Container for medicament automatic injector and automatic injector adapted therefor - Google Patents
Container for medicament automatic injector and automatic injector adapted therefor Download PDFInfo
- Publication number
- WO2005046765A2 WO2005046765A2 PCT/US2004/036497 US2004036497W WO2005046765A2 WO 2005046765 A2 WO2005046765 A2 WO 2005046765A2 US 2004036497 W US2004036497 W US 2004036497W WO 2005046765 A2 WO2005046765 A2 WO 2005046765A2
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- WO
- WIPO (PCT)
- Prior art keywords
- container
- automatic injector
- needle
- clip
- automatic
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/3278—Apparatus for destroying used needles or syringes
- A61M2005/3284—Deformaton of needle by deflection or bending
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
Definitions
- the present invention relates to outer containers or housings for carrying and storing medicament automatic injectors before and after use of the injectors.
- the present invention also relates to a clip for carrying one or more of the containers.
- a medicament automatic injector is a device designed to allow a user to self- administer a pre-measured dose of a medicament composition subcutaneously or intramuscularly, usually in an emergency situation.
- Automatic injectors are used, for example, to treat anaphylactic (severe allergic) reactions and to administer antidotes for certain poisons, such as chemical nerve agents.
- One of the most well known automatic injectors is the automatic injector sold under the name EPIPEN ® by Meridian Medical Technologies, Inc. (Columbia, Maryland, United States), which delivers epinephrine.
- a typical automatic injector has a housing, inside of which is a cartridge.
- the cartridge has one or several chambers containing medicament compositions or components thereof and is adapted to be attached to a needle assembly.
- the automatic injector can house a premixed dosage of medicament, liquid dosages that are mixed prior to injection, or a solid medicament that is dissolved in a liquid transport solution prior to injection.
- the housing carries an actuation assembly with a stored energy source, for example, a compressed spring. Activation of the actuation assembly causes a sequence of movements, the medicament compound is subsequently forced through the needle and into the user.
- the automatic injector is of the type designed to carry several components of the medicament composition in separate, sealed compartments, structure may be included that forces the components to m n ix when the actuation assembly is activated.
- a needle typically extends from the housing.
- Automatic injectors are typically packaged in containers to keep them clean and protect them from damage.
- the typical automatic injector container is not designed to house the automatic injector after use.
- the automatic injector package comprises an automatic injector, a container, and indicia.
- the automatic injector includes a housing, a cartridge assembly carried within the housing, a needle assembly operatively associated with the cartridge assembly, and an actuation assembly carried by the housing.
- the actuation assembly includes a stored energy source and a drive assembly driven by the stored energy source.
- the drive assembly is operatively associated with the cartridge assembly and the needle assembly to expel a medicament from the cartridge and through the needle assembly upon activation of the automatic injector.
- the container is constructed and arranged to receive the automatic injector before and after use. At least a portion of the container is formed from a light permeable material.
- the indicia are provided on at least one of the housing and the container and are visible by a user when the automatic injector has been placed into the container after use. The indicia point to an indicating portion that indicates that the automatic injector has been used.
- a container for an automatic injector comprises an open end and a closed end opposite the open end.
- a cap is constructed and arranged to releasably engage the open end so as to releasably close the open end.
- a needle retainer is mounted within the container proximate to the closed end. A position of the needle retainer relative to the closed end is such that the distance between the needle retainer and the closed end is shorter than the length of a protruding needle of the automatic injector.
- a further aspect of the invention relates to a method for using an automatic injector including a cartridge and needle assembly coupled to an actuation assembly including a stored energy source.
- the method comprises storing the automatic injector in a container in an unused condition.
- the automatic injector is used, resulting in the extension of a needle.
- the automatic injector is returned to the container after use, thereby causing the automatic injector to be retained in the container by engagement of the extended needle with retaining structure provided within the container.
- FIGURE 1 is a perspective view of an automatic injector container according to an embodiment of the present invention.
- FIGURE 2 is a side e ⁇ evational view of the container of FIGURE 1 with the container's cap removed;
- FIGURE 3 is a perspective view of the cap
- FIGURE 4 is a longitudinal cross-sectional view of the container of FIGURE 1, illustrating an unused automatic injector within the container;
- FIGURE 5 A is a longitudinal cross-sectional view of a portion of the container similar to the view of FIGURE 4, illustrating the administration end of the automatic injector within the container prior to use;
- FIGURE 5B is a longitudinal cross-sectional view similar to that of FIGURE 5 A, illustrating the administration end of the automatic injector after the automatic injector has been used and returned to the container;
- FIGURE 6A is a perspective view of the exterior of the container with the automatic injector in the position illustrated in FIGURE 5 A;
- FIGURE 6B is a perspective view of the exterior of the container with the automatic injector in the used position illustrated in FIGURE 5B, showing a used injector indicator flag visible from the exterior of the container;
- FIGURE 7 is a side elevational view of a portion of the exterior of a container according to another embodiment of the present invention.
- FIGURE 8A is a longitudinal cross-sectional view of a portion of the container of FIGURE 8, illustrating an unused automatic injector within the container;
- FIGURE 8B is a longitudinal cross-sectional view similar to that of FIGURE 8 A, illustrating the administration end of the automatic injector after the automatic injector has been used and returned to the container;
- FIGURE 9A is a longitudinal cross-sectional view of a container according to another embodiment of the invention with an automatic injector installed therein;
- FIGURE 9B is a longitudinal cross-sectional view of the container of FIGURE 9 A without the automatic injector;
- FIGURES 10A and 10B are side elevational views of the container with an automatic injector installed therein before and after use, respectively;
- FIGURE 11 is a perspective view of a needle retainer that is installed within the container of FIGURES 9A and 9B;
- FIGURE 12 is a top plan view of the needle retainer of FIGURE 11;
- FIGURE 13 is a side elevational view of the needle retainer of FIGURE 11;
- FIGURE 14 is an isolated perspective view of a shield that is installed within the container of FIGURES' 9 A and 9B;
- FIGURE 15 is a sectional perspective view of the shield of FIGURE 14;
- FIGURE 16 is a sectional side elevational view of a portion of the container of FIGURES 9A and 9B with an automatic injector installed therein after use of the automatic injector, illustrating the needle of the automatic injector in a crippled position;
- FIGURE 17 is a side elevational view of the exterior of the container of FIGURES 9A and 9B;
- FIGURE 18 is a perspective view of an S-clip that may be used to attach two containers according to the invention.
- FIGURE 19 is a top plan view of the S-clip of FIGURE 18.
- FIGURE 20 is a side elevational view of the S-clip of FIGURE 18.
- FIGURE 1 is a perspective view of a container, generally indicated at 10, according to one embodiment of the invention.
- the container 10 is generally cylindrical and is sized to contain an automatic injector (not shown in FIGURE 1).
- the container 10 may be used with any type or variety of automatic injector known in the art.
- the container 10 would be distributed with an automatic injector inside, and would thus serve, at least in part, as product packaging for the automatic injector. Accordingly, the central exterior surface 12 of the container 10 provides space for product labeling, usage directions, or other necessary indicia. Such labeling and indicia may be printed on labels and attached to the exterior surface 12, or they may be formed or printed on the central exterior surface 12 during the manufacture of the container 10.
- the container 10 may be made of a conventional plastic material such as polypropylene (PP).
- PP polypropylene
- the container 10, or portions thereof, may also be made of more penetration resistant materials, such as poly(ethylene terephthalate) (PET), as will be explained below in more detail.
- PET poly(ethylene terephthalate)
- the container 10 has a closed needle-receiving end, generally indicated at 14, and an open end 16 opposite the needle-receiving end 14.
- the opening 24 in the open end 20 is of sufficient size to allow an automatic injector to be removed and replaced.
- the open end 16 is covered by a removable cap 18.
- FIGURE 2 is a side elevational view of the container 10 with the cap 18 removed.
- FIGURE 3 is a perspective view of the cap 18 in isolation.
- the open end 16 of the container 10 includes threads 20 that engage corresponding threads 22 on the interior of the cap 18 to releasably engage the cap 18 and container 10.
- Two sets of six individual non-contiguous helical threads 20 are provided on container 10, and the cap includes a corresponding set of conventional contiguous threads 22.
- This arrangement allows the cap 18 to start threading onto the container 10 when placed on the container 10 in a number of initial positions, and thus making it easier to thread the cap 18 on the container 10.
- a conventional set of threads may be used on the cap 18 and container 10.
- the exterior surface of the cap 18 may also be provided with a number of contoured portions spaced around its circumference in order to provide the user with a better grip when opening or closing the cap 18.
- the container 10 is designed to house an automatic injector such that its needle- bearing end extends toward the needle-receiving end 14 of the container 10.
- the needle- receiving end 14 of the container 10 may have a smaller diameter than the rest of the container 10, depending on the diameter of the automatic injector that it is designed to accommodate, so as to encourage users to insert the automatic injector in the proper orientation.
- the container 10 of the illustrated embodiment has a gradual taper, from more narrow toward the needle-receiving end 14 to broader near the cap 18. That taper corresponds to the contours of one type of automatic injector; many other contours are possible.
- the container 10 is designed to house an automatic injector with the needle-bearing end of the automatic injector facing the needle-receiving end 14 of the container 10, it is possible that the automatic injector may be, placed in the container, accidentally or deliberately, such that the needle-bearing end of the automatic injector faces the cap 18.
- the cap 18 is preferably made of a material of sufficient thickness, durability, and penetration resistance such that if the automatic injector were to be accidentally activated with the needle-bearing end facing the cap 18, the protruding needle would not penetrate the cap 18.
- one wall of the cap 18, such as the top wall, indicated by reference numeral 19 in FIGURE 4 may be particularly thickened or may be provided with a "pad" of penetration resistant material, either plastic or metal, secured to an inward surface thereof.
- the material of which the needle-receiving end 14 is made is at least partially translucent and, in some embodiments, may be fully transparent. In other embodiments, the needle-receiving end 14 may be translucent, partially translucent, or opaque, with particular portions that are fully or partially transparent.
- the entire container 10 may also be made of a translucent or transparent material. This feature and its utility will be described in more detail below.
- the container 10 and cap 18 may be capable of blocking or absorbing ultraviolet (UV) light.
- UV-absorbing agent could be added to the polymer mix from which the container 10 is formed. Many such UV-absorbing agents are known in the polymer and molding arts. UV blocking or absorbing capability helps to ensure that the medicament within the automatic injector is not compromised by exposure to UV light, even if the container 10 is significantly light permeable.
- the bottom 26 of the needle-receiving end 14 has a shock-absorbing eyelet 28.
- the eyelet 28 takes the form of an arc of material that extends across the bottom 26 of the needle-receiving end 14.
- the eyelet 28 acts as a shock absorber to absorb at least some of the force if the container 10 is dropped and the bottom 26 of the needle-receiving end 14 impacts another surface.
- the eyelet 28 would also allow a user to attach a carrying strap, so that the container may be conveniently carried.
- the eyelet 28 may provide from about 1mm to about 5mm of clearance for the attachment of a strap. In other embodiments of the invention, there may be significant clearance between the eyelet 28 and the bottom 26.
- FIGURE 4 is a longitudinal cross-sectional view of the container 10 showing an automatic injector 50 installed therein.
- the automatic injector 50 illustrated in FIGURE 4 has a single chamber and is designed to contain and inject a single component liquid medicament composition.
- the container 10 may also be used with two component wet/wet mixing automatic injectors, as well as two component wet/dry mixing automatic injectors, and any other type of automatic injector known in the art.
- the automatic injector 50 is shown schematically in FIGURE 4 and certain features have been omitted for clarity of illustration, because the workings of the automatic injector 50 are not critical to the functioning of this embodiment of the container 10. Full details of operation for automatic injectors such as automatic injector 50 may be found in commonly assigned U.S. Patent Nos. 5,391,151 and 6,210,369, the contents of which are incorporated by reference herein.
- the automatic injector 50 has an outer housing 52 and a cartridge 54 disposed within the outer housing 52.
- the cartridge 54 includes a medicament storage compartment 56, an attached needle assembly 58, and a plunger 60 at the top of the medicament storage compartment 56.
- the cartridge 54 may include one or two compartments, so as to accommodate medications having a wet component and a dry component (so-called “wet/dry automatic injectors”) or a wet component and another wet component (so-called “wet/wet automatic injectors”).
- wet/dry automatic injectors a wet component and a dry component
- wet/wet automatic injectors a wet component and another wet component
- Descriptions of several suitable types of wet/dry automatic injectors can be found in commonly-assigned U.S. Patent Nos. 6,641,561 and 6,770,052. The entire contents of those applications are incorporated by reference herein in their entirety.
- the automatic injector 50 also includes an actuation assembly, only portions of which are shown in FIGURE 4.
- a stored energy source (not shown in FIGURE 4), such as a compressed spring, would be carried in the space above the plunger 60.
- a safety cap 62 prevents the stored energy source from releasing and activating the device.
- the precise manner of activation of the automatic injector 50 is not critical to the container 10; however, in a typical automatic injector 50, the safety cap 62 would be removed and the needle end 64 of the automatic injector 50 would be pressed against an administration site (e.g., the user's thigh), causing a relative movement of upper 66 and lower 68 portions of the housing 52 that causes the stored energy source to deploy and activate the automatic injector 50.
- an administration site e.g., the user's thigh
- the upper portion 66 of the housing 52 includes an inwardly extending shoulder 70 against which the lower portion 68 of the housing bears.
- the stored energy source propels the needle 72 through its protective sleeve 74 and the bottom 76 of the housing 52 and subsequently causes the plunger 60 to move downward, causing the medicament compound in the cartridge 54 to be dispensed through the needle 72.
- internal spring force exerted against the needle 72 prevents the needle 72 from being retracted back into the housing 52 once it has been used.
- FIGURE 4 illustrates the position of the automatic injector 50 within the container 10 prior to use.
- the automatic injector 50 is completely within the container 10 and the container 10 is slightly longer than the automatic injector 50. Therefore, when the user removes the cap 18, he or she will have to tip the container 10 to remove the automatic injector 50 from it. This is advantageous because if the automatic injector 50 did protrude from the container 10, the user might try to remove it from the container 10 by tugging on or near the safety cap 62, which might cause the safety cap 62 to come loose and could ultimately result in the premature or unintended activation of the automatic injector 50.
- the difference in length between the container 10 and the automatic injector 50 is most desirably the smallest length difference between the two that will prevent the user from accidentally removing the safety cap 62. That difference may be no more than a few millimeters.
- the container 10 should be as small as possible, so that it can be conveniently and consistently carried by a user. If the container 10 is too large, the user may not be inclined to carry it, in which case the automatic injector 50 may not be available when it is needed. '
- FIGURE 5 A is a longitudinal cross-sectional view of a portion of the automatic injector 50, showing its "administration end" within the container 10.
- the interior of the container 10 has a small inwardly extending circumferential shoulder or shelf 78 formed at the top of the needle-receiving end 14 of the container 10.
- An indicator sleeve 80 has an outwardly extending lip 82 that rests on the shelf 78.
- the indicator sleeve 80 is formed of a brightly colored material that can be penetrated by the needle 72 (e.g. red plastic).
- the indicator sleeve 80 is covered by a cover sleeve 84, which surrounds and covers the indicator sleeve 80.
- the indicator sleeve 80 includes a prong or series of prongs 86 that are engaged by corresponding clips 88 on the end of the cover sleeve 84 to retain the cover sleeve 84 in the position illustrated in FIGURE 5A. To some extent, the indicator sleeve 80 and cover sleeve 84 also cushion the automatic injector 50 against shock and impact.
- the user When the user needs to use the automatic injector 50, he or she removes the cap 18 from the container 10, removes the automatic injector 50 from the container 10 as was described above, and then uses the automatic injector 50 in accordance with the manufacturer's instructions. Once the automatic injector 50 is used, the user replaces the automatic injector 50 in the container 10, inserting the automatic injector 50 such that the needle 72 is oriented toward the needle-receiving end 14 of the container 10. If the automatic injector 50 is difficult to re-insert, the user may place the cap 18 on the container 10 and turn the cap 18 toward engagement with the container 10. As the user turns the cap 18, the torque applied to the cap 18 will cause an axial force to be exerted on the automatic injector 50, forcing it into the container 10. The cap 18 may thus provide the user with a significant mechanical advantage if used to "seat" the used automatic injector 50 within the container 10 in this manner.
- the motion of the needle 72 causes a series of movements, which may result in the position shown in FIGURE 5B. Specifically, as the needle 72 is moved into the container, it penetrates the bottom of the indicator sleeve 80, disengages the cover sleeve 84 from the indicator sleeve 80, and drives the cover sleeve 84 downward, toward the bottom of the container 10.
- FIGURES 6A and 6B are perspective views of the container 10 before and after the used automatic injector 50 has been replaced in the container 10, respectively.
- the indicator sleeve 80 is clearly visible through a translucent window 88 in the needle-receiving portion 14, whereas in FIGURE 6 A, only the uncolored cover sleeve 84 is visible in the translucent window 88.
- the needle 72 of the automatic injector may range in length from about 0.4 inches (approximately 10 millimeters) to 0.975 inches (approximately 24.8 millimeters). If the needle 72 is sufficiently long, the automatic injector 50 will not be fully seated in the container 10 when the needle 72 strikes the bottom of the container 10. In that case, as the user pushes the automatic injector 50 fully into the container 10, the needle 72 bends and becomes crippled, as shown in FIGURE 5B.
- the bottom 26 of the container 10 and the cover sleeve 84 may be used to cripple the needle, it is advantageous if those components are made of or lined with a tough material that resists penetration, such as PET.
- a reinforcing plate of either plastic or metal could be fixed to the cover sleeve 84 or the inside bottom 26 of the container 10. Embodiments of the invention that employ a reinforcing component at the bottom of the container will be described below in more detail.
- the penetrated indicator sleeve 80 acts as a retaining member and exerts a frictional force on the needle 72 that opposes an attempt to remove the automatic injector 50 from the container 10.
- the indicator sleeve 80, or its bottom portion 81 may be made of a thermoplastic elastomer having a relatively high coefficient of friction so as to produce the greatest possible amount of friction when in engagement with the needle 72. Additionally, if the needle 72 is of a length that causes it to be crippled by striking the bottom 26 of the container 10, the crippled needle 72 itself may make the used automatic injector 50 difficult to remove from the container 10.
- a cover sleeve 84 is moved by the needle 72 of the automatic injector 50
- other embodiments are possible.
- a green indicator flag could be shown through the window 88 until the used automatic injector 50 is inserted into the container 10, at which time the needle 72 of the automatic injector 50 would cause the green indicator flag to be moved to reveal a white or red "used" indicator flag.
- This could be implemented, for example, by making the cover sleeve 84 green and the underlying indicator sleeve 80 either white or red.
- a green indicator flag or sleeve could be covered by another movable sleeve.
- FIGURE 7 is an elevational view of the needle-receiving end 114 of a container 100 according to another embodiment of the invention.
- the needle-receiving end 114 is sufficiently transparent to allow the needle 72 of the automatic injector 50 to be seen from the outside of the container 110. Therefore, the needle 72 itself acts as an indicator that the automatic injector 50 has been used.
- the container 100 has pointing indicia 115 inscribed on the outer surface of the needle-receiving end 114 to direct the user's attention to the portion of the needle-receiving end 114 where the needle 72 is visible when the automatic injector 50 has been used.
- the pointing indicia 115 may be painted, marked, integrally formed, or applied as labels to the needle-receiving end 114. If desired, the pointing indicia 115 may also be omitted.
- FIGURES 8A and 8B are longitudinal cross-sectional views of the portion of the container 100 shown in FIGURE 7.
- the interior mechanism is simpler than in the container 10 of the previous embodiment.
- FIGURE 8 A illustrates the position of the automatic injector 50 in the container 100 before activation.
- the bottom of the automatic injector 50 rests on a needle retainer 180, which is a flexible, resilient component, typically made of a thermoplastic elastomer, that cushions the automatic injector 50 before use.
- the needle 72 penetrates and advances through the needle retainer 180.
- the needle 72 can then be seen through a transparent window 188 in the needle-receiving portion 114, indicating that the automatic injector has been used.
- the needle retainer 180 exerts a frictional force on the needle 72 that tends to oppose an attempt to remove it. If the needle 72 is long enough, it may strike the bottom 182 of the needle-receiving portion 114 and become crippled, as shown in FIGURE 8B.
- the crippled needle 72 may also make the used automatic injector 50 difficult to remove from the container 100.
- the bottom 182 of the container 100 would be made of a penetration resistant material, or reinforced with such a material, so as to facilitate needle crippling.
- FIG. 1 Other embodiments of containers according to the invention may combine the features of the two embodiments described above to provide a colored, highly visible "used" indicator in combination with a simplified container that is designed to retain a used automatic injector.
- the indicator function may be provided as a portion of the automatic injector itself.
- FIGURES 9A and 9B are longitudinal cross-sectional views of a container, generally indicated at 200, according to another embodiment of the invention.
- FIGURE 9 A shows the container 200 with an exemplary automatic injector 202, also in longitudinal cross-section;
- FIGURE 9B shows the container 200 in longitudinal cross-section without the automatic injector 202.
- the container 200 includes many of the features of the containers 10 and 100 that were described above. Certain features that are not shown in FIGURES 9A and 9B, such as an eyelet 28, may also be included in the container 200.
- the automatic injector 202 has an actuation assembly, generally indicated at 250, a chamber, generally indicated at 252, that is made of glass, plastic, or another suitable material and is configured to contain a medicament solution, and a hub and needle assembly, generally indicated at 254.
- the automatic injector 202 may be of the type designed to carry a two component wet/dry medicament or a two component wet/wet medicament, in which case it would have two chambers separated by an appropriate sealing structure.
- US Patent Nos. 6,641,561 and 6,770,052 provide details on the construction of such automatic injectors and their sealing and mixing structures.
- the actuation assembly 250 includes a safety cap 256 mounted on the rear end of the automatic injector 202.
- the safety cap 256 includes a downwardly extending safety pin 258 formed on the inward side of the top surface of the cap 256.
- the safety pin 258 extends between and engages spring fingers 260 formed in the split rearward portion of a collet 262.
- the spring fingers 260 each have semi-conical end surfaces 264 that are constructed and arranged to engage corresponding semi-conical surfaces 266 arrayed around an aperture 268 in the rear of the inner housing portion 270 of the automatic injector 202.
- the engagement of the safety pin 258 with the spring fingers 260 keeps them spread apart and prevents them from deflecting inwardly to enter the aperture 268.
- the collet 262 is surrounded by a cylindrical sleeve having an inwardly extending flange at the rearward end thereof.
- the collet 262 has a forward annular flange 272.
- a coil spring 274 surrounds the collet 262 and is compressed between the flange of the cylindrical sleeve and the annular flange 272. At its forward end, the collet 262 engages a spacer-indicator member 276.
- the spacer-indicator member 276 is a brightly colored component, typically made of red plastic or the equivalent, that includes one end configured to receive and engage the collet 262 and the other end configured to receive and engage a plunger 278 positioned sealingly within the chamber 252 for sliding movement therein. (Alternatively, the spacer- indicator member 276 may engage an insert connected to the plunger 278.)
- the spacer- indicator member 276 is generally cylindrical in shape, and may be varied in overall length so as to allow the plunger 278 to be initially positioned within the chamber 252 at any desired position.
- the spacer-indicator member 276 may be made with a longer length, so that plunger 278 is initially positioned further along the length of the chamber 252 and the effective volume of the chamber 252 is thus reduced. Therefore, when the volume of the medicament dose is smaller than the volume of the chamber 252, a spacer- indicator member 276 of an appropriate length can reduce the possibility that an air bubble will accumulate in the unused volume of the chamber 252.
- the safety cap 256 is manually removed from the automatic injector 202, thus the safety pin 258 is removed from its initial position separating the spring fingers 264.
- the spring fingers 262 are forced upward and, by interaction with the semi-conical surfaces 266, toward one another and off of the retaining surfaces of the flange.
- the compressed spring 274 is then free to release its stored energy to move the collet 262 forwardly under the force of the spring 262, causing the needle 72 to extend through the forward portion of the housing 280 and the medicament to be injected.
- FIGURES 10A and 10B are side elevational views of a container 200 with an automatic injector 202 installed therein before and after use of the automatic injector 202, respectively.
- the container 200 and automatic injector 202 are both preferably made of a material that is at least partially translucent and, more preferably, a material that is at least partially transparent, such as a transparent or substantially transparent plastic.
- labels 282 containing identifying information, patient instructions, and other necessary indicia are placed over portions of the automatic injector 202, leaving a transparent window 284 at a position adjacent to the position into which the spacer-indicator member 276 moves after use of the automatic injector 202.
- the transparent window 284 is empty and clear.
- the spacer-indicator 276 has moved into the transparent window 284, giving the user a highly visible indication that the automatic injector 202 has been used.
- portions of the housing of the automatic injector 202 could be made of an opaque plastic and the transparent window 284 could be made of a transparent plastic.
- the spacer-indicator 276 is generally not configured to be centered in the transparent window 284 once the automatic injector 202 has been used. Rather, as shown in FIGURE 10B, it is typically designed to be positioned slightly below center, which provides more visibility at tolerance extremes.
- the container 200 has a mechanism for retaining the needle 72 of the automatic injector 202 similar to that of the container 100 illustrated in FIGURES 7, 8 A, and 8B.
- the needle-receiving end 204 of the container 200 has an inner circumferential shelf 206. Resting on the inner circumferential shelf 206 is a needle retainer 208.
- the needle retainer 208 is slightly larger in diameter than the diameter of the container 200 itself, such that the needle retainer 208 engages the inner walls of the container 200 with an interference fit. Other arrangements are possible; in certain embodiments, the needle retainer 208 may be fused in place, secured with adhesives, snapped in place, or welded in place.
- the needle retainer 208 is formed of a resilient material and, because of its thickness and resilience, acts as a shock absorber, cushioning the automatic injector 202 before use. The cushioning effect of the needle retainer 208 reduces or eliminates the need for an external structure such as an eyelet 28.
- FIGURES 11, 12, and 13 are perspective, top plan, and side elevational views, respectively, of the needle retainer 208. As shown, the needle retainer 208 is substantially circular.
- the needle retainer 208 includes two vent slots 211 spaced 180° from each other along the circumference of the needle retainer 208. The vent slots 211 ensure that pressure does not build up on one side of the needle retainer 208 and enable any gases or vapors to move out of the container 200.
- the container 200 also has a vent hole 210, which is shown in FIGURE 9B.
- a vent hole 210 In the center of the upper surface of the needle retainer 208 is a raised central portion 214.
- a similar raised central portion 216 is provided on the bottom surface, as shown in FIGURE 13.
- the raised central portions 214, 216 provide the needle retainer 208 with a greater effective thickness in the area through which the needle 72 will be inserted, thereby improving the frictional "grip" of the needle retainer 208 on the needle 72 and also aid gating of the tool during the manufacturing process.
- the needle retainer 208 also includes a number of protuberances 219 spaced regularly around its circumference.
- the protuberances 219 improve the manufacturability of the container 200 and its assembly process by making it easier to separate stacked needle retainers 208 during manufacturing and assembly.
- needle retainers 208 may be made without the raised central portions 214, 216 and the protuberances 219.
- a shield 212 which is held in place both by engagement with the inner circumferential shelf 206 and by the fit of the needle retainer 208 above it.
- the shield 212 is substantially cap- shaped and rests on the bottom of the needle-receiving end 204 of the container with its open end facing upwards.
- the shield 212 is intended to prevent the needle 72 from penetrating the container 200.
- the shield 212 would be made of stainless steel or another metal that is compatible with (i.e., not corroded or otherwise damaged by) the medicament in the automatic injector 202.
- the shield 212 may be made of PET or another penetration resistant plastic.
- FIGURE 14 is a perspective view of the shield 212 in isolation
- FIGURE 15 is a sectional perspective view of the shield 212 in isolation.
- the conical portion 220 increases the possibility that a shorter needle will be crippled after insertion into the container 200.
- the upwardly extending conical portion 220 also reduces the amount of feree necessary to deflect and cripple the needle 72.
- the shield 212 need not include a conical projection 220 per se; an upward projection of the shield 212, if provided, could have substantially any shape.
- the needle 72 is of sufficient length to strike the shield 212 and become crippled, its final position after contact with the shield 212 may be that shown in FIGURE 16, a sectional side elevational view of a portion of the needle-receiving end 204 of the container 200.
- the shield 212 in addition to the conical portion 220, the shield 212 also includes an upwardly extending flange 222 that helps to prevent any portion of the crippled, deformed needle 72 from escaping the area enclosed by the shield 212 and the needle retainer 208.
- the spacing between the needle retainer 208 and the shield 212 adds to the cushioning and shock absorbing effect of the needle retainer 208, because the needle retainer 208 can deflect and rebound to dissipate shock.
- the container 200 includes a central upward projection 224 that extends upwardly from the bottom of the container 200 and coincides in position with the conical portion 220 of the shield 212.
- the projection 224 may be used to center the shield 212 when the shield is inserted into the container 200, and it may also reinforce the conical portion 220, particularly if the conical portion 220 deflects downwardly in response to initial contact with the needle 72.
- the projection 224 is not provided.
- FIGURE 17 is a side elevational view of the exterior of the container 200.
- the exterior of the container 200 also includes certain advantageous features.
- a frosted grip area 300 increases the tactility of the surface and encourages a firm grip.
- a smooth recessed surface 302 provides a location for a clip or other such retaining device to be attached around the circumference of the container 200.
- the recessed surface 302 is also preferably transparent and may be used as a window so that users and treating medical professionals can determine whether the automatic injector 202 is in the container 200 and, if so, what drug it contains.
- labels on the automatic injector 202 describing its medicament would be placed so as to coincide with the position of the recessed surface 302. Because the surface 302 is recessed, it is less likely to become scratched and obscure the interior of the container 200. Additionally, labels on the automatic injector 202 may be visible through portions of the container 200 other than the frosted grip area 300.
- a flange 304 on the upper portion of the container 200 defines the position to which the user will need to screw the cap 18 in order to ensure that the needle 72 is crippled after it enters the container 200. (Typically, the arrangement of the container 200 and the cap 18 is such that a small vent gap is left between the two when the cap 18 is screwed down fully.)
- the container 200 also includes two anti-roll protrusions 306 spaced opposite one another on the lower portion of the outer surface of the container 200.
- the anti-roll protrusions 306 reduce the likelihood that the container 200 will roll more than about 180° from the position in which it is placed.
- the container 200 does not include an eyelet 28, its bottom surface 308 is rounded, which helps to dissipate shock if the container 200 is dropped on its end.
- the recessed surface 302 provides a surface over which a clip may be placed to attach multiple containers 200 to one another. Such clips may be used on other containers 10, 100 according to the invention, although the recessed surface 302 substantially prevents a clip from sliding along the length of the container 200.
- FIGURE 18 is a perspective view of an S-clip, generally indicated at 308, that may be used with containers 10, 100, 200 according to the invention.
- FIGURES 19 and 20 are, respectively, a top plan view and a side elevational view of the clip 308.
- the clip 308 is contoured such that it has two clip openings 310, with each clip opening 310 configured to accept one container 10, 200, 300.
- the two clip openings 310 are opposite one another, and the portions of the clip 308 that define each opening 310 are joined by a central web of material 311.
- the clip 308 may be formed from any suitable material that permits the clip to 308 to flex and engage the side of the container 10, 200, 300.
- the engaging surfaces 312 that define the interior of each of the clip openings 310 have a different radius of curvature than that of the containers 10, 200, 300.
- the different radius of curvature of the engaging surfaces 312 and the containers 10, 200, 300 allows the clip 308 to engage a container with minimal contact between the engaging surfaces 312 and the container 10, 100, 200. Minimal contact between the engaging surfaces 312 and the container 200 reduces the likelihood that the engaging surfaces 312 of the clip 308 will scratch the transparent recessed surface 302 of the container 200.
- the overall "S" shape of the clip 308 will reduce the amount of force needed to remove a container 10, 100, 200 from the clip 308 in an emergency, as compared with a more conventional double C-clip. Additionally, texture 314 on the outer surface of the clip 308 makes the clip 308 easier to grip and may encourage users to replace the container 10, 100, 200 in the clip 308 once the automatic injector 50, 202 has been used. It is contemplated that the clip 308 may include a suitable attachment assembly for carrying the clip on a belt or securing to an article of clothing or desired surface or article.
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Catching Or Destruction (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Packages (AREA)
- Packaging Of Annular Or Rod-Shaped Articles, Wearing Apparel, Cassettes, Or The Like (AREA)
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04800616A EP1684828B1 (en) | 2003-11-04 | 2004-11-03 | Container for medicament automatic injector and automatic injector adapted therefor |
CA002544520A CA2544520A1 (en) | 2003-11-04 | 2004-11-03 | Container for medicament automatic injector and automatic injector adapted therefor |
DK04800616.7T DK1684828T3 (en) | 2003-11-04 | 2004-11-03 | Automatic medicine injector container and automatic injector adapted to it |
JP2006538443A JP4881741B2 (en) | 2003-11-04 | 2004-11-03 | Container for automatic syringe for medicine and automatic syringe adapted therefor |
DE602004025964T DE602004025964D1 (en) | 2003-11-04 | 2004-11-03 | CONTAINER FOR AN AUTOMATIC INJECTOR WITH ASSOCIATED AUTOMATIC INJECTOR |
AT04800616T ATE460193T1 (en) | 2003-11-04 | 2004-11-03 | CONTAINER FOR AN AUTOMATIC INJECTOR WITH ASSOCIATED AUTOMATIC INJECTOR |
AU2004289228A AU2004289228B2 (en) | 2003-11-04 | 2004-11-03 | Container for medicament automatic injector and automatic injector adapted therefor |
IL175429A IL175429A (en) | 2003-11-04 | 2006-05-04 | Container for medicament automatic injector and automatic injector adapted therefor |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US51673303P | 2003-11-04 | 2003-11-04 | |
US60/516,733 | 2003-11-04 | ||
US51791003P | 2003-11-07 | 2003-11-07 | |
US60/517,910 | 2003-11-07 |
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WO2005046765A3 WO2005046765A3 (en) | 2005-08-04 |
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PCT/US2004/036497 WO2005046765A2 (en) | 2003-11-04 | 2004-11-03 | Container for medicament automatic injector and automatic injector adapted therefor |
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US (1) | US7635348B2 (en) |
EP (1) | EP1684828B1 (en) |
JP (1) | JP4881741B2 (en) |
AT (1) | ATE460193T1 (en) |
AU (1) | AU2004289228B2 (en) |
CA (1) | CA2544520A1 (en) |
DE (1) | DE602004025964D1 (en) |
DK (1) | DK1684828T3 (en) |
ES (1) | ES2342399T3 (en) |
IL (1) | IL175429A (en) |
TW (1) | TW200518799A (en) |
WO (1) | WO2005046765A2 (en) |
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009092430A1 (en) * | 2008-01-24 | 2009-07-30 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Syringe system and method for the production thereof |
WO2010089589A1 (en) * | 2009-02-05 | 2010-08-12 | The Medical House Plc | Autoinjector having an outer packaging and a needle sheath removing means |
WO2010081838A3 (en) * | 2009-01-14 | 2010-09-23 | Novartis Ag | Encasing a sterile prefilled container |
US8162887B2 (en) | 2004-06-23 | 2012-04-24 | Abbott Biotechnology Ltd. | Automatic injection devices |
EP2476450A1 (en) * | 2011-08-29 | 2012-07-18 | Novo Nordisk A/S | A pen needle container and a method for bending a needle cannula |
US8636704B2 (en) | 2009-04-29 | 2014-01-28 | Abbvie Biotechnology Ltd | Automatic injection device |
US8647299B2 (en) | 2006-01-23 | 2014-02-11 | The Medical House Limited | Autoinjector supporting the syringe at the front |
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US8708968B2 (en) | 2011-01-24 | 2014-04-29 | Abbvie Biotechnology Ltd. | Removal of needle shields from syringes and automatic injection devices |
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US9265887B2 (en) | 2011-01-24 | 2016-02-23 | Abbvie Biotechnology Ltd. | Automatic injection devices having overmolded gripping surfaces |
US9943649B2 (en) | 2011-09-22 | 2018-04-17 | Abbvie Inc. | Automatic injection device |
US9981087B2 (en) | 2011-09-22 | 2018-05-29 | Abbvie Inc. | Automatic injection device |
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US11642462B2 (en) | 2006-01-23 | 2023-05-09 | Shl Medical Ag | Injection device |
US11918794B2 (en) | 2017-11-02 | 2024-03-05 | Sanofi | Button and button assembly for a drug delivery device |
Families Citing this family (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2314182T3 (en) | 2002-02-11 | 2009-03-16 | Antares Pharma, Inc. | INTRADERMIC INJECTOR. |
FR2852851B1 (en) * | 2003-03-25 | 2006-01-06 | Sedat | NEEDLE PROTECTION DEVICE FOR SYRINGE, AND INJECTION DEVICE COMPRISING SYRINGE AND PROTECTIVE DEVICE |
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US9168107B2 (en) | 2004-11-09 | 2015-10-27 | Startbox, Llc | System and method for preventing wrong-site surgeries |
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US7297136B2 (en) * | 2004-12-06 | 2007-11-20 | Wyrick Ronald E | Medicine injection devices and methods |
US7905352B2 (en) * | 2004-12-06 | 2011-03-15 | Washington Biotech Corporation | Kits containing medicine injection devices and containers |
US20110226646A1 (en) * | 2004-12-06 | 2011-09-22 | Wyrick Ronald E | Kits Containing Medicine Injection Devices And Containers |
DE102004063650B4 (en) * | 2004-12-31 | 2022-10-20 | Ypsomed Ag | Lifetime indicator for a product metering device |
BRPI0614025A2 (en) | 2005-01-24 | 2012-12-25 | Antares Pharma Inc | jet injectors |
US9022980B2 (en) | 2005-02-01 | 2015-05-05 | Kaleo, Inc. | Medical injector simulation device |
EP1904145A2 (en) * | 2005-07-06 | 2008-04-02 | Washington Biotech Corp. | Method and apparatus for delivering epinephrine |
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US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
WO2007131013A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Two-stage reconstituting injector |
GB2437922B (en) * | 2006-05-10 | 2010-12-08 | Owen Mumford Ltd | Injection device comprising a window and a shutter element |
US20070293582A1 (en) * | 2006-06-05 | 2007-12-20 | Malcolm Hill | Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms |
CA2683949A1 (en) * | 2007-04-18 | 2008-10-30 | Meridian Medical Technologies, Inc. | Container for an automatic injector |
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FR2922457B1 (en) * | 2007-10-23 | 2010-10-29 | Plastef Investissements | SYRINGE DEVICE WITH PROTECTIVE CAP. |
EP2990067B1 (en) | 2008-03-10 | 2019-09-04 | Antares Pharma, Inc. | Injector safety device |
JP5836120B2 (en) | 2008-05-20 | 2015-12-24 | アヴァント・メディカル・コーポレーション | Auto injector system |
US8052645B2 (en) | 2008-07-23 | 2011-11-08 | Avant Medical Corp. | System and method for an injection using a syringe needle |
US8177749B2 (en) * | 2008-05-20 | 2012-05-15 | Avant Medical Corp. | Cassette for a hidden injection needle |
EP3581224A1 (en) | 2008-08-05 | 2019-12-18 | Antares Pharma, Inc. | Multiple dosage injector |
US8366682B2 (en) | 2009-03-04 | 2013-02-05 | Washington Biotech Corporation | Medicine injection apparatuses |
US8579865B2 (en) | 2009-03-20 | 2013-11-12 | Antares Pharma, Inc. | Hazardous agent injection system |
US10350364B2 (en) | 2009-11-11 | 2019-07-16 | Windgap Medical, Inc. | Portable Drug Mixing and Delivery Device and Associated Methods |
US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
US8627816B2 (en) | 2011-02-28 | 2014-01-14 | Intelliject, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
US9022990B2 (en) | 2011-04-04 | 2015-05-05 | Tech Group Europe Limited | Needle safety shield |
PL2699293T3 (en) | 2011-04-20 | 2019-08-30 | Amgen Inc. | Autoinjector apparatus |
US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
EP2572741A1 (en) * | 2011-09-23 | 2013-03-27 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device and actuation mechanism for a drug delivery device |
FI2822618T3 (en) | 2012-03-06 | 2024-03-21 | Antares Pharma Inc | Prefilled syringe with breakaway force feature |
WO2013152323A1 (en) | 2012-04-06 | 2013-10-10 | Wotton Paul K | Needle assisted jet injection administration of testosterone compositions |
USD898908S1 (en) | 2012-04-20 | 2020-10-13 | Amgen Inc. | Pharmaceutical product cassette for an injection device |
USD808010S1 (en) | 2012-04-20 | 2018-01-16 | Amgen Inc. | Injection device |
US9364611B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
WO2014029679A1 (en) * | 2012-08-20 | 2014-02-27 | Sanofi-Aventis Deutschland Gmbh | Cap for a drug delivery device and drug delivery device |
US9050416B2 (en) | 2012-11-01 | 2015-06-09 | Tech Group Europe Limited | Needle Safety device with floating ring |
EP2939224B1 (en) | 2012-12-27 | 2019-11-06 | Kaleo, Inc. | Devices, systems and methods for locating and interacting with medicament delivery systems |
WO2014124427A1 (en) | 2013-02-11 | 2014-08-14 | Travanty Michael | Needle assisted jet injection device having reduced trigger force |
ES2742046T3 (en) | 2013-03-11 | 2020-02-12 | Antares Pharma Inc | Dose injector with pinion system |
US20150025472A1 (en) * | 2013-03-12 | 2015-01-22 | Robert Dax Colwell | Cover for a syringe and method of making |
WO2014165136A1 (en) | 2013-03-12 | 2014-10-09 | Antares Pharma, Inc. | Constant volume prefilled syringes and kits thereof |
US10092703B2 (en) | 2013-03-15 | 2018-10-09 | Amgen Inc. | Drug cassette, autoinjector, and autoinjector system |
EP3593839A1 (en) | 2013-03-15 | 2020-01-15 | Amgen Inc. | Drug cassette |
US9907910B2 (en) | 2013-03-15 | 2018-03-06 | Windgap Medical, Inc. | Portable drug mixing and delivery device and associated methods |
US10569017B2 (en) | 2013-03-15 | 2020-02-25 | Windgap Medical, Inc. | Portable drug mixing and delivery device and associated methods |
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EP2823841A1 (en) | 2013-07-09 | 2015-01-14 | Sanofi-Aventis Deutschland GmbH | Autoinjector |
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US11116903B2 (en) | 2014-08-18 | 2021-09-14 | Windgap Medical, Inc | Compression seal for use with a liquid component storage vial of an auto-injector |
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US9415176B1 (en) | 2015-01-22 | 2016-08-16 | West Pharmaceutical Services, Inc. | Autoinjector having an end-of-dose visual indicator |
AU2016266657B2 (en) | 2015-04-15 | 2020-09-17 | Windgap Medical, Llc | Removable actuating cap for use with an auto-injector assembly |
US10814059B2 (en) * | 2015-07-10 | 2020-10-27 | Fresenius Kabi Deutschland Gmbh | Syringe packaging system |
CA2994300C (en) | 2015-08-13 | 2023-12-05 | Windgap Medical, Inc. | Mixing and injection device with sterility features |
USD818587S1 (en) | 2016-03-29 | 2018-05-22 | Abbevie Inc. | Automatic injection device |
USD819198S1 (en) | 2016-04-28 | 2018-05-29 | Amgen Inc. | Autoinjector with removable cap |
WO2018136413A2 (en) | 2017-01-17 | 2018-07-26 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and event detection |
EP3381491A1 (en) | 2017-03-28 | 2018-10-03 | Tecpharma Licensing AG | Pen cap for an injection device comprising a needle destroyer |
EP3645083A1 (en) | 2017-06-30 | 2020-05-06 | Regeneron Pharmaceuticals, Inc. | Auto-injector with anti-roll features |
JP1629610S (en) | 2017-10-25 | 2019-04-15 | ||
US20210077710A1 (en) * | 2017-12-21 | 2021-03-18 | Inject Pharma Sweden Ab | Auto injector set for oxygen reduced packaging |
USD932006S1 (en) | 2018-11-21 | 2021-09-28 | Regeneron Pharmaceuticals, Inc. | Auto-injector cap |
USD903856S1 (en) | 2018-06-29 | 2020-12-01 | Regeneron Pharmaceuticals, Inc. | Auto-injector |
US11929160B2 (en) | 2018-07-16 | 2024-03-12 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and compliance detection |
US20200140175A1 (en) * | 2018-11-02 | 2020-05-07 | Entegris, Inc. | Multi piece fitment for a fluid container |
USD1010811S1 (en) | 2019-09-30 | 2024-01-09 | Amgen Inc. | Handheld drug delivery device |
USD1030041S1 (en) | 2020-01-14 | 2024-06-04 | Amgen Inc. | Handheld drug delivery device |
USD1030040S1 (en) | 2020-01-14 | 2024-06-04 | Amgen Inc. | Handheld drug delivery device |
US20230051213A1 (en) * | 2020-02-06 | 2023-02-16 | Eli Lilly And Company | Drug container systems including lock-out mechanisms |
USD974547S1 (en) | 2020-11-05 | 2023-01-03 | Amgen Inc. | Handheld drug delivery device |
USD973866S1 (en) | 2020-11-05 | 2022-12-27 | Amgen Inc. | Handheld drug delivery device |
JP2021500644S (en) | 2020-11-05 | 2022-12-27 | Syringe | |
USD985117S1 (en) | 2021-03-10 | 2023-05-02 | Amgen Inc. | Handheld drug delivery device |
USD985116S1 (en) | 2021-03-10 | 2023-05-02 | Amgen Inc. | Handheld drug delivery device |
CN117083093A (en) * | 2021-03-10 | 2023-11-17 | 美国安进公司 | Drug delivery device with removable cap |
USD985118S1 (en) | 2021-03-10 | 2023-05-02 | Amgen Inc. | Handheld drug delivery device |
USD985119S1 (en) | 2021-03-30 | 2023-05-02 | Amgen Inc. | Handheld drug delivery device |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5137516A (en) * | 1989-11-28 | 1992-08-11 | Glaxo Group Limited | Triggered application device for medicament to be more descriptive of the invention |
US5358489A (en) * | 1993-05-27 | 1994-10-25 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
EP0634140A1 (en) * | 1992-09-26 | 1995-01-18 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Applicator for tissue adhesive |
US5695472A (en) * | 1993-05-27 | 1997-12-09 | Washington Biotech Corporation | Modular automatic or manual emergency medicine injection system |
US6241709B1 (en) * | 1994-05-30 | 2001-06-05 | B D Medico S.A.R.L. | Injection device |
WO2001078806A1 (en) * | 2000-04-18 | 2001-10-25 | Baske Pty Ltd. | Syringe retaining device and spoon for injectables |
US20020050462A1 (en) * | 2000-05-12 | 2002-05-02 | Melinda Penney | Cases for medication delivery devices |
US20040069667A1 (en) * | 2000-05-12 | 2004-04-15 | Tomellini Dalita R. | Cases for medication delivery devices |
Family Cites Families (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US69667A (en) * | 1867-10-08 | Improvement in horse-bakes | ||
US50462A (en) * | 1865-10-17 | Improved sewed shoe | ||
US1506429A (en) * | 1921-03-21 | 1924-08-26 | Kahn Alfred | Pocket medical case |
US1711594A (en) * | 1927-04-28 | 1929-05-07 | Holden T Gillespie | Syringe container |
US1838825A (en) * | 1929-01-31 | 1931-12-29 | Aaron A Goldstein | Sterilizing case |
US1718701A (en) * | 1929-04-05 | 1929-06-25 | O'sullivan David Lee | Vest-pocket hypodermic-syringe container |
US2400722A (en) * | 1944-07-10 | 1946-05-21 | Harry L Swan | Hypodermic needle case |
US3363497A (en) * | 1966-09-21 | 1968-01-16 | Grossman Music Corp | Recorder |
US3367486A (en) * | 1966-11-16 | 1968-02-06 | Pharmaseal Lab | Hypodermic syringe package |
SE411516B (en) * | 1977-10-26 | 1980-01-14 | Reenstierna E G B | DEVICE FOR DESTRUCTION OF AN INJECTION SPRAYER |
US4188950A (en) * | 1978-10-30 | 1980-02-19 | Wardlaw Stephen C | Disposable syringe |
FR2583979B1 (en) * | 1985-07-01 | 1987-08-21 | Merieux Inst | PROCESS FOR THE SERIAL PREPARATION OF SELF-INJECTION SYRINGES IN A SEALED CONTAINER, FOR LYOPHILIZED MEDICINAL PRODUCT, AND DEVICE FOR CARRYING OUT SAID METHOD |
US4634428A (en) * | 1985-08-15 | 1987-01-06 | Cuu Cwo Liang | Cover for a disposable syringe |
US4735311A (en) * | 1986-04-09 | 1988-04-05 | The West Company | Needle shield assembly |
US4728321A (en) * | 1987-04-16 | 1988-03-01 | Ming-Chiu Wu | Syringe cap with adhesive holding plug |
US4728320A (en) * | 1987-04-17 | 1988-03-01 | Chen Chang Cheng | Syringe cap with hammer |
JPS63264075A (en) * | 1987-04-22 | 1988-10-31 | 陳 昌政 | Injection needle treatment cap for disposable syringe |
US5074848A (en) * | 1988-06-02 | 1991-12-24 | Burt Wayne R | Needle receptacle |
US5172808A (en) * | 1988-07-01 | 1992-12-22 | John Bruno | Device for safely transporting one or more hypodermic needles or the like from point of use to point of ultimate disposal |
US4872552A (en) * | 1988-11-16 | 1989-10-10 | Mid-South Products Engineering, Inc. | Safety packaging for hypodermic syringes with needles and the like |
US4877132A (en) * | 1989-03-20 | 1989-10-31 | Luke Makris | Syringe protection device |
US5161681A (en) * | 1989-04-24 | 1992-11-10 | Kemp David R | Safety container for hypodermic syringes |
US5080651A (en) * | 1989-06-02 | 1992-01-14 | Jullien Robert G | Combined protective guard and destruction system for a syringe |
US5015234A (en) * | 1989-06-02 | 1991-05-14 | Jullien Robert G | Syringe guard apparatus |
US5002533A (en) * | 1989-09-05 | 1991-03-26 | Jullien Robert G | Syringe guard apparatus |
US5188600A (en) * | 1989-06-02 | 1993-02-23 | Jullien Robert G | Syringe guard apparatus |
US5104375A (en) * | 1989-10-16 | 1992-04-14 | Johnson & Johnson Medical, Inc. | Locking holder for a pair of syringes and method of use |
US5232454A (en) * | 1990-08-01 | 1993-08-03 | Smiths Industries Medical Systems, Inc. | Safety needle container |
US5232455A (en) * | 1991-01-07 | 1993-08-03 | Smiths Industries Medical Systems, Inc. | Syringe with protective housing |
GB9100819D0 (en) * | 1991-01-15 | 1991-02-27 | Medimech Int Ltd | Subcutaneous injector |
US5156267A (en) * | 1991-06-14 | 1992-10-20 | Dynamic Bio-Apparatuses, Inc. | Syringe inhibiting container |
US5084027A (en) * | 1991-07-19 | 1992-01-28 | Bernard Daniel H | Needle cover with safety disposal chamber |
US5519931A (en) * | 1994-03-16 | 1996-05-28 | Syncor International Corporation | Container and method for transporting a syringe containing radioactive material |
US5417326A (en) * | 1994-03-31 | 1995-05-23 | Winer; Donald B. | Syringe container |
US5941854A (en) * | 1994-12-19 | 1999-08-24 | Bhitiyakul; Somsak | Intravenous catheter |
US5522503A (en) * | 1994-12-20 | 1996-06-04 | Halbich; Frank | Syringe case |
US5566828A (en) * | 1995-02-21 | 1996-10-22 | The Upjohn Company | Locking package for a syringe |
US5918443A (en) * | 1995-04-05 | 1999-07-06 | Phillips; Paul B. | Medical syringe containment |
US6155420A (en) * | 1995-04-05 | 2000-12-05 | Phillips; Paul B. | Medical syringe container |
FR2734485B1 (en) * | 1995-05-24 | 1997-10-10 | Biodome | PRE-FILLED SAFETY SYRINGE |
US6026959A (en) * | 1996-07-22 | 2000-02-22 | Protec Medical Corporation | Protective kit for medical sharps and method for using same |
DE19717033A1 (en) * | 1997-04-23 | 1998-11-12 | Schott Glas | Needle cap for a prefillable disposable syringe |
US6454746B1 (en) * | 1997-06-04 | 2002-09-24 | Eli Lilly And Company | Medication delivery apparatus |
JP2002508225A (en) * | 1997-12-16 | 2002-03-19 | メリディアン メディカル テクノロジーズ,インコーポレイテッド | Automatic syringe |
DE29801168U1 (en) | 1998-01-24 | 1999-08-12 | Medico Dev Investment Co | Injection device |
US6001082A (en) * | 1998-02-20 | 1999-12-14 | Becton Dickinson And Company | Medication delivery pen with an integral magnifying pocket clip |
JP3983884B2 (en) * | 1998-03-20 | 2007-09-26 | メディキット株式会社 | Safety syringe |
US5950827A (en) * | 1998-10-08 | 1999-09-14 | Odom; Jeffrey L. | Injector pen storage case |
CA2251863A1 (en) * | 1998-10-20 | 2000-04-20 | Zoni Inc. | Belt system for housing medical device |
US6217558B1 (en) * | 1998-12-17 | 2001-04-17 | Filiberto P. Zadini | Apparatus for blood vessel type differentiation for syringes and guidewires placement devices |
DE29822494U1 (en) * | 1998-12-17 | 2000-05-04 | Medico Development Investment Co., Ascona | Injection device |
EP1171185B1 (en) * | 1999-04-16 | 2005-11-02 | Becton Dickinson and Company | Pen style injector with automated substance combining feature |
US6702785B1 (en) * | 2000-05-04 | 2004-03-09 | Collins Sonya Dene | Needle capper |
US6482733B2 (en) * | 2000-05-15 | 2002-11-19 | Asm Microchemistry Oy | Protective layers prior to alternating layer deposition |
US6576918B1 (en) * | 2000-08-09 | 2003-06-10 | Syncor International Corp. | Container and method for transporting a syringe containing radioactive material |
US6770052B2 (en) * | 2000-10-10 | 2004-08-03 | Meridian Medical Technologies, Inc. | Wet/dry automatic injector assembly |
US6641561B1 (en) * | 2000-10-10 | 2003-11-04 | Meridian Medical Technologies, Inc. | Drug delivery device |
US6796962B2 (en) * | 2001-03-15 | 2004-09-28 | Specialized Health Products, Inc. | Safety shield for medical needles |
US20030132128A1 (en) * | 2002-01-11 | 2003-07-17 | Mazur David P. | Container for syringe |
US6767336B1 (en) * | 2003-01-09 | 2004-07-27 | Sheldon Kaplan | Automatic injector |
-
2004
- 2004-11-02 US US10/978,827 patent/US7635348B2/en not_active Expired - Fee Related
- 2004-11-03 TW TW093133463A patent/TW200518799A/en unknown
- 2004-11-03 DE DE602004025964T patent/DE602004025964D1/en active Active
- 2004-11-03 AT AT04800616T patent/ATE460193T1/en not_active IP Right Cessation
- 2004-11-03 DK DK04800616.7T patent/DK1684828T3/en active
- 2004-11-03 JP JP2006538443A patent/JP4881741B2/en not_active Expired - Fee Related
- 2004-11-03 AU AU2004289228A patent/AU2004289228B2/en not_active Ceased
- 2004-11-03 WO PCT/US2004/036497 patent/WO2005046765A2/en active Application Filing
- 2004-11-03 CA CA002544520A patent/CA2544520A1/en not_active Abandoned
- 2004-11-03 ES ES04800616T patent/ES2342399T3/en active Active
- 2004-11-03 EP EP04800616A patent/EP1684828B1/en not_active Not-in-force
-
2006
- 2006-05-04 IL IL175429A patent/IL175429A/en not_active IP Right Cessation
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5137516A (en) * | 1989-11-28 | 1992-08-11 | Glaxo Group Limited | Triggered application device for medicament to be more descriptive of the invention |
EP0634140A1 (en) * | 1992-09-26 | 1995-01-18 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Applicator for tissue adhesive |
US5358489A (en) * | 1993-05-27 | 1994-10-25 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
US5695472A (en) * | 1993-05-27 | 1997-12-09 | Washington Biotech Corporation | Modular automatic or manual emergency medicine injection system |
US6241709B1 (en) * | 1994-05-30 | 2001-06-05 | B D Medico S.A.R.L. | Injection device |
WO2001078806A1 (en) * | 2000-04-18 | 2001-10-25 | Baske Pty Ltd. | Syringe retaining device and spoon for injectables |
US20020050462A1 (en) * | 2000-05-12 | 2002-05-02 | Melinda Penney | Cases for medication delivery devices |
US20040069667A1 (en) * | 2000-05-12 | 2004-04-15 | Tomellini Dalita R. | Cases for medication delivery devices |
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US8162887B2 (en) | 2004-06-23 | 2012-04-24 | Abbott Biotechnology Ltd. | Automatic injection devices |
US9017287B2 (en) | 2004-06-23 | 2015-04-28 | Abbvie Biotechnology Ltd | Automatic injection devices |
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US11642462B2 (en) | 2006-01-23 | 2023-05-09 | Shl Medical Ag | Injection device |
US8647299B2 (en) | 2006-01-23 | 2014-02-11 | The Medical House Limited | Autoinjector supporting the syringe at the front |
US8679061B2 (en) | 2006-06-30 | 2014-03-25 | Abbvie Biotechnology Ltd | Automatic injection device |
US9486584B2 (en) | 2006-06-30 | 2016-11-08 | Abbvie Biotechnology Ltd. | Automatic injection device |
US8747357B2 (en) | 2006-12-18 | 2014-06-10 | The Medical House Limited | Autoinjector |
WO2009092430A1 (en) * | 2008-01-24 | 2009-07-30 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Syringe system and method for the production thereof |
EP2179759B1 (en) * | 2008-10-27 | 2015-11-25 | Meridian Medical Technologies, Inc. | Automatic injector with needle cover |
WO2010081838A3 (en) * | 2009-01-14 | 2010-09-23 | Novartis Ag | Encasing a sterile prefilled container |
GB2467637B (en) * | 2009-02-05 | 2013-09-11 | Medical House Ltd | An autoinjector device with removable external packaging |
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US9339610B2 (en) | 2011-01-24 | 2016-05-17 | Abbvie Biotechnology Ltd | Removal of needle shield from syringes and automatic injection devices |
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US8708968B2 (en) | 2011-01-24 | 2014-04-29 | Abbvie Biotechnology Ltd. | Removal of needle shields from syringes and automatic injection devices |
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US11918794B2 (en) | 2017-11-02 | 2024-03-05 | Sanofi | Button and button assembly for a drug delivery device |
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Also Published As
Publication number | Publication date |
---|---|
AU2004289228A1 (en) | 2005-05-26 |
IL175429A0 (en) | 2006-09-05 |
JP2007510465A (en) | 2007-04-26 |
WO2005046765A3 (en) | 2005-08-04 |
CA2544520A1 (en) | 2005-05-26 |
JP4881741B2 (en) | 2012-02-22 |
AU2004289228B2 (en) | 2010-08-12 |
DE602004025964D1 (en) | 2010-04-22 |
ES2342399T3 (en) | 2010-07-06 |
IL175429A (en) | 2011-09-27 |
TW200518799A (en) | 2005-06-16 |
US20050148933A1 (en) | 2005-07-07 |
ATE460193T1 (en) | 2010-03-15 |
DK1684828T3 (en) | 2010-07-12 |
US7635348B2 (en) | 2009-12-22 |
EP1684828A2 (en) | 2006-08-02 |
EP1684828B1 (en) | 2010-03-10 |
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