WO2005013867A2 - Device for treating nighttime breathing problems - Google Patents
Device for treating nighttime breathing problems Download PDFInfo
- Publication number
- WO2005013867A2 WO2005013867A2 PCT/BE2004/000112 BE2004000112W WO2005013867A2 WO 2005013867 A2 WO2005013867 A2 WO 2005013867A2 BE 2004000112 W BE2004000112 W BE 2004000112W WO 2005013867 A2 WO2005013867 A2 WO 2005013867A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- shaped part
- adjusting screw
- slide element
- connecting means
- slide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/56—Devices for preventing snoring
- A61F5/566—Intra-oral devices
Definitions
- the invention relates to a device for treating breathing problems, in particular to an oral apparatus, comprising a shaped part fitting onto the teeth of the lower jaw, a shaped part fitting onto the teeth of the upper jaw, and adjustable connecting means between the upper and lower shaped part for forward/backward and upward/downward adjustment of the upper shaped part relative to the lower shaped part.
- Nighttime breathing problems which can for instance result in snoring, sleep apnoea syndrome or other sleep disorders, are a generally known problem.
- the rear part of the tongue may tend to slide backwards and so wholly or partially close off the pharyngeal airway.
- an adjustable hook is used which is connected by means of a forward/backward adjustable screw to the upper shaped part and can be coupled to the lower shaped part.
- a hook has the drawback that it still allows a certain upward/downward movement, which causes an inaccuracy in the vertical (upward/ downward) adjustment.
- Such a hook is furthermore irritating for the tongue and can come loose during sleep.
- the invention has for its object to provide a device according to the preamble of claim 1 which is more user- friendly, in particular is more agreeable to wear, and allows a precise forward/backward and upward/downward adjustment with a limited freedom of movement of the lower jaw in relation to the upper jaw.
- the device according to the preamble of claim 1 is distinguished for this purpose in that one of the shaped parts is provided at the front with a slide mechanism consisting of a slide element which is slidable laterally to a limited extent along a guide element, and that the adjustable connecting means are fixedly connected to the other shaped part on one side and to the slide element on the other.
- a slide mechanism By arranging a slide mechanism between the adjustable connecting means and one of the shaped parts a limited lateral movement of the lower shaped part relative to the upper shaped part is made possible.
- This slide mechanism operates independently of the adjustable connecting means and thus allows a precise upward/downward and forward/backward adjustment, without this adjustment being impeded by the slide mechanism.
- By arranging the slide mechanism on the front of the shaped part for instance as closely as possible to the rear side of the front teeth in the position placed in the mouth, there is more space for the tongue and the movement of the tongue is impeded as little as possible.
- the term "shaped part” must be interpreted broadly here, and is understood to mean for instance a brace with a palate plate as well as a flexible bite-block.
- the dimensions of the guide element and the slide element are closely-sized transversely of the guiding direction.
- the slide element is hereby substantially immobile in the plane perpendicularly of the guiding direction, and the vertical (upward/downward) adjustment is not affected by the lateral freedom of movement provided by the slide mechanism.
- the guide element is a rod mounted between two points of the one shaped part, and the slide element is a hollow tube slidable around this rod.
- the length of the hollow tube can be chosen as a function of the desired maximum lateral displacement.
- Many other variants of the slide mechanism are of course also possible which likewise fall within the scope of the invention, and some examples of which are given in the figure description.
- the slide element can preferably be snapped onto the guide element.
- These so-called “snap-on" slide elements have the advantage that the shaped parts can each be placed separately in the mouth, whereafter the slide element is snapped onto the guide element.
- the adjustable connecting means preferably comprise a substantially vertical adjusting screw with double screw thread for upward/downward adjustment of the upper shaped part relative to the lower shaped part, which adjusting screw co-acts on one outer end with a first threaded bore connected via a connecting piece to the slide element, and which co- acts on its other outer end with a second threaded bore provided on the front side of the other shaped part, wherein a rotation of the adjusting screw changes the distance between the lower and upper threaded bores.
- the vertical adjusting screw is provided substantially in the middle with an encircling flange with radially directed openings in which a rod fits for the purpose of turning the adjusting screw through rotation of the rod.
- a rod fits for the purpose of turning the adjusting screw through rotation of the rod.
- Such adjusting screws with double screw thread are already used in orthodontics, and in particular in braces for widening the upper or lower jaw, wherein the screw is built in between two parts of a palate plate.
- the vertical adjusting screw is preferably enclosed on both sides by telescopically acting tubes.
- the connecting piece is provided with a horizontal adjusting screw for forward/backward adjustment of the one shaped part relative to the other, which horizontal adjusting screw co-acts on one outer end with a threaded passage mounted on the slide element.
- the horizontal adjusting screw is preferably provided on its other outer end with a screw head, and the connecting piece is provided with a horizontally oriented hole through which the horizontal adjusting screw extends.
- the adjustable connecting means are at least partially received in a housing which is rounded on the outside such that the device feels soft in the mouth of the patient.
- fig. 1 is a perspective view of a possible embodiment of the device according to the invention
- fig. 2 is a front view of the embodiment of figure 1
- fig. 3 is a rear view of the embodiment of figure 1
- fig. 4 is a side view of the embodiment of figure 1
- fig. 5A, B show a number of embodiment variants of the slide mechanism of the device according to the invention
- fig. 6 is a perspective view of a second embodiment of the device according to the invention
- fig. 7 is a perspective view of a third embodiment of the device according to the invention.
- the embodiment shown in figure 1 comprises a shaped part 2 fitting onto the teeth of the lower jaw, referred to hereafter as lower shaped part, and a shaped part 1 fitting onto the teeth of the upper jaw, referred to hereafter as upper shaped part.
- these shaped parts can for instance also take the form of braces with a metal arch and palate plate.
- the adjustable connecting means for forward/ backward adjustment, as indicated with arrow P2, and for upward/downward adjustment, as indicated with arrow PI, of the upper shaped part relative to the lower will now be elucidated.
- the adjustable connecting means comprise a substantially vertical adjusting screw 4 with double screw thread for upward/downward adjustment (PI) .
- Adjusting screw 4 is provided substantially in the middle with an encircling flange 5 with radially directed openings 10 into which a rod 12 fits.
- This adjusting screw 4 is rotated at one end in a first threaded bore 13 and at its other end in a second threaded bore 13' provided on the upper shaped part 1.
- the screw 4 is rotated deeper into threaded bores 13, 13' such that the distance between the lower and upper threaded bores 13, 13', and therefore also the distance between upper and lower shaped parts, changes.
- a rotation of the screw through a quarter-turn corresponds for instance to a difference in distance of 0.2 mm. In this manner the vertical distance between upper and lower shaped part can thus be adjusted precisely.
- the lower shaped part 2 is provided at the front with a slide .mechanism which consists of a slide element 8 slidable laterally to a limited extent along a guide element 9.
- Guide element 9 is here a rod fixed between two points on the lower shaped part, and the slide element 8 is a hollow tube slidable around this rod.
- the dimensions of guide element 9 and slide element 8 are closely-sized transversely of the guiding direction, i.e.
- the slide element is substantially immobile in the direction perpendicular to the guiding direction.
- the length of hollow tube 8 can be chosen as a function of the desired maximum lateral displacement.
- a relatively short tube 8 and a relatively long guide element 9 such that the lateral freedom of movement is increased.
- the slide mechanism can be embodied in many other ways; some possible embodiment variants are shown in figures 5A and B. According to the variant of figure 5A, a block-shaped slide element is used which is guided in a hollow tube provided on the top with a slot 20.
- Figure 5B shows another variant wherein the guide element consists of a cylindrical tube provided on the top with a slot 21.
- Slide element 8 here takes a spherical form so that, in addition to the sliding movement, a limited swinging movement is also possible in the plane perpendicularly of slot 2 and parallel to the guiding direction.
- the adjustable connecting means are fixedly connected to upper shaped part 2 on one side and to slide element 8 on the other. So as to make wearing of the device as pleasant as possible, it is recommended that the adjustable connecting means are at least partially received in a housing which is rounded on the outside.
- Figure 6 shows a second embodiment variant of the device according to the invention.
- Guide element 9 is provided here with two extra hollow tubes 8', 8", whereby the lateral movement of the slide element is limited further.
- These hollow tubes 8, 8', 8" can all be embodied as snap-on elements which can be snapped easily onto the guide element.
- FIG. 6 shows a third embodiment variant of the device according to the invention.
- the slide element is here provided with a passage through which extends the guide element 9.
- the horizontal adjusting screw 6 is placed the other way around, with its head 11 at the rear side, and a counter nut 27 is mounted on the end of the screw 6 (at the front side) .
- the device has to be taken out of the mouth whereupon the position of the horizontal adjusting screw 6 can be adjusted with a screwdriver.
- the adjustable connecting means 22 for the upward/downward adjustment of the upper shaped part relative to the lower shaped part are even more compact in the third embodiment and are partially provided with a soft envelope. Said connecting means for the upward/downward adjustment can be partially built in the upper shaped part, so that the discomfort for the user is minimal.
- the adjustment connecting means comprise a vertical screw thread 27, a nut 24 fitting thereon, and a housing 25 provided with a threaded bore (not shown) co-acting with the screw thread 27.
- a threaded bore (not shown) co-acting with the screw thread 27.
- the shaped parts between which the connecting means are acting need to be taken out of the mouth and turned relative to each other around the axis of the screw thread 27, whereby the screw thread extends more or less deep in the threaded bore, i.e. in the housing. In that way the vertical distance between the upper and lower shaped part can be adjusted precisely with a very compact construction.
- a counter nut 24 which is screwed up to the housing and fixes the whole.
Landscapes
- Health & Medical Sciences (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Nursing (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Percussion Or Vibration Massage (AREA)
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04761473A EP1659998B1 (en) | 2003-08-08 | 2004-08-04 | Device for treating nighttime breathing problems |
DE602004017331T DE602004017331D1 (en) | 2003-08-08 | 2004-08-04 | Device for the treatment of nocturnal breathing problems |
CA2535112A CA2535112C (en) | 2003-08-08 | 2004-08-04 | Device for treating nighttime breathing problems |
AU2004262450A AU2004262450B2 (en) | 2003-08-08 | 2004-08-04 | Device for treating nighttime breathing problems |
US10/567,372 US7832402B2 (en) | 2003-08-08 | 2004-08-04 | Device for treating nighttime breathing problems |
DK04761473T DK1659998T3 (en) | 2003-08-08 | 2004-08-04 | Apparatus for treating nocturnal respiratory problems |
JP2006522184A JP4709146B2 (en) | 2003-08-08 | 2004-08-04 | Device for treating nocturnal breathing disorders |
US11/902,264 US20080072915A1 (en) | 2003-08-08 | 2007-09-20 | Device for treating nighttime breathing problems |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE2003/0441 | 2003-08-08 | ||
BE2003/0441A BE1015642A3 (en) | 2003-08-08 | 2003-08-08 | Device for the treatment of nocturnal breathing problems. |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/567,372 A-371-Of-International US7832402B2 (en) | 2003-08-08 | 2004-08-04 | Device for treating nighttime breathing problems |
US11/902,264 Continuation-In-Part US20080072915A1 (en) | 2003-08-08 | 2007-09-20 | Device for treating nighttime breathing problems |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2005013867A2 true WO2005013867A2 (en) | 2005-02-17 |
WO2005013867A3 WO2005013867A3 (en) | 2005-06-30 |
WO2005013867B1 WO2005013867B1 (en) | 2005-08-18 |
Family
ID=34120391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/BE2004/000112 WO2005013867A2 (en) | 2003-08-08 | 2004-08-04 | Device for treating nighttime breathing problems |
Country Status (11)
Country | Link |
---|---|
US (1) | US7832402B2 (en) |
EP (1) | EP1659998B1 (en) |
JP (1) | JP4709146B2 (en) |
AT (1) | ATE411786T1 (en) |
AU (1) | AU2004262450B2 (en) |
BE (1) | BE1015642A3 (en) |
CA (1) | CA2535112C (en) |
DE (1) | DE602004017331D1 (en) |
DK (1) | DK1659998T3 (en) |
ES (1) | ES2311841T3 (en) |
WO (1) | WO2005013867A2 (en) |
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WO2007113465A1 (en) * | 2006-04-04 | 2007-10-11 | Sleepworks Products Ltd | Device to reduce snoring and sleep apnoea |
WO2008141372A1 (en) * | 2007-05-17 | 2008-11-27 | Michael Stubbs | Mandibular advancement device |
WO2009049602A1 (en) * | 2007-10-19 | 2009-04-23 | Schmitt-Bylandt Juergen | System for mandibular protrusion to prevent snoring and apnea |
DE102008007281A1 (en) | 2008-02-02 | 2009-08-06 | Rainer Hamann | Intraoral therapy device for prevention of snoring and obstructive sleep apnea, is designed for forward displacement of mandible relative to maxilla and extension of rear throat, and guide element is mounted before tooth rows of jaw shell |
WO2010003198A2 (en) * | 2008-07-07 | 2010-01-14 | Jozef Frans Nelissen | Device for treating night time breathing problems |
DE102012003564B3 (en) * | 2012-02-23 | 2013-06-20 | Bernd Scheffel | Device for improving the breathing of a person |
DE102016001977A1 (en) | 2015-02-24 | 2016-08-25 | Fahri Yildiz | Infinitely adjustable lower jaw protrusion splint for the treatment of snoring and obstructive sleep apnea |
CN113143406A (en) * | 2020-12-14 | 2021-07-23 | 南通市肿瘤医院 | Tumour clamping device for oral and maxillofacial surgery |
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US20090032030A1 (en) * | 2007-07-30 | 2009-02-05 | Callender R Sam | Apparatus for treatment of sleep apnea |
ES1069826Y (en) * | 2008-07-17 | 2009-09-04 | Carlos Villafranca Felix De | IMPROVED MANDIBULAR ADVANCE DEVICE |
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US8550816B2 (en) * | 2009-06-24 | 2013-10-08 | Kosmo Technologies, Llc | Mandibular manipulator and related methods |
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US8684006B2 (en) * | 2010-03-26 | 2014-04-01 | Advanced Brain Monitoring, Inc. | Systems and methods for optimizing oral appliance therapy for the treatment of sleep apnea |
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US20210267790A1 (en) * | 2014-07-22 | 2021-09-02 | Arora, Llc | Oral Dental Appliance for Improving Breathing |
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USD752760S1 (en) * | 2015-02-11 | 2016-03-29 | Respire Medical Holdings, LLC | Oral sleep appliance |
KR101660922B1 (en) * | 2015-04-02 | 2016-09-28 | 기분좋은세상 주식회사 | Orthodontic appliance for temporomandibular joint |
US10258319B2 (en) | 2015-05-18 | 2019-04-16 | Richard L. Arden | Airway assist device and method |
US10010313B2 (en) | 2015-05-18 | 2018-07-03 | Richard L. Arden | Mandibular subluxation device and method |
US10342526B2 (en) | 2015-07-01 | 2019-07-09 | Richard L. Arden | Airway assist device and method |
CN106963540A (en) * | 2016-01-13 | 2017-07-21 | 周星 | Turbine and worm type tractor for embedded type tongue pulling device |
JP6719265B2 (en) * | 2016-04-26 | 2020-07-08 | 三井化学株式会社 | Mouthpiece |
KR101791035B1 (en) * | 2016-09-22 | 2017-10-27 | 기분좋은세상 주식회사 | Orthodontic appliance for temporomandibular joint |
US10905582B2 (en) | 2017-01-26 | 2021-02-02 | Koncept Innovators Llc | Mandibular advancement device |
US11123219B2 (en) * | 2018-04-05 | 2021-09-21 | Oscar TAMEZ | Mouth appliance and a method to improve breathing during sleep and exercise |
US11045348B2 (en) * | 2018-05-08 | 2021-06-29 | Archis Health Investments LLC | Apparatus for mandibular advancement of an oral appliance |
AU2019275944A1 (en) * | 2018-05-30 | 2020-12-24 | Innovgas Pty Ltd | Adjustable bite block with passageway |
FR3092752A1 (en) | 2019-02-18 | 2020-08-21 | Charles Botbol | Oral immobilization device in protrusion of the mandibular arch, manufacturing process |
EP3927292B1 (en) | 2019-02-18 | 2023-04-05 | Botbol, Charles | Adjusting device, measurement, recording of mandibular protrusion occlusion reports, application to mandibular protrusion immobilization apparatus |
FR3092751B1 (en) | 2019-02-18 | 2023-12-22 | Charles Botbol | Device for adjusting, measuring, recording occlusion ratios in mandibular protrusion, application to an immobilization device in mandibular protrusion |
IT202000004555A1 (en) * | 2020-03-04 | 2021-09-04 | Antonio Nardiello | MANDIBULAR ADVANCE DEVICE |
WO2021236569A1 (en) * | 2020-05-20 | 2021-11-25 | Arora, Llc | Oral dental appliance for improving breathing |
EA039297B1 (en) * | 2020-12-30 | 2021-12-30 | Республиканское Инновационное Унитарное Предприятие "Научно-Технологический Парк Бнту "Политехник" | Intraoral dental device |
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US5281133A (en) * | 1992-11-16 | 1994-01-25 | Ormco Corporation | Rapid palatal expansion device |
US5409017A (en) * | 1994-01-19 | 1995-04-25 | The University Of British Columbia | Mandible repositioning appliance |
US5868138A (en) * | 1993-04-13 | 1999-02-09 | Silent Knight Ventures, Inc. | Dental appliance for treatment of snoring and obstructive sleep apnea |
EP1247498A1 (en) * | 2001-04-02 | 2002-10-09 | Leone S.p.A. | Process for making an expansion screw for orthodontics and screw thus made |
US6729335B1 (en) * | 1993-04-13 | 2004-05-04 | Silent Knights Ventures Inc. | Dental appliance for treatment of snoring and obstructive sleep apnea |
US6769910B1 (en) * | 1999-09-09 | 2004-08-03 | Don A. Pantino | Methods and apparatus for improved interocclusal mandibular repositioning with adjustable relational members |
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US4901737A (en) * | 1987-04-13 | 1990-02-20 | Toone Kent J | Method and therapeutic apparatus for reducing snoring |
-
2003
- 2003-08-08 BE BE2003/0441A patent/BE1015642A3/en not_active IP Right Cessation
-
2004
- 2004-08-04 DK DK04761473T patent/DK1659998T3/en active
- 2004-08-04 AU AU2004262450A patent/AU2004262450B2/en not_active Ceased
- 2004-08-04 JP JP2006522184A patent/JP4709146B2/en not_active Expired - Fee Related
- 2004-08-04 US US10/567,372 patent/US7832402B2/en not_active Expired - Fee Related
- 2004-08-04 AT AT04761473T patent/ATE411786T1/en active
- 2004-08-04 EP EP04761473A patent/EP1659998B1/en not_active Expired - Lifetime
- 2004-08-04 WO PCT/BE2004/000112 patent/WO2005013867A2/en active Application Filing
- 2004-08-04 ES ES04761473T patent/ES2311841T3/en not_active Expired - Lifetime
- 2004-08-04 DE DE602004017331T patent/DE602004017331D1/en not_active Expired - Lifetime
- 2004-08-04 CA CA2535112A patent/CA2535112C/en not_active Expired - Fee Related
Patent Citations (7)
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US3854208A (en) * | 1973-01-19 | 1974-12-17 | G Arant | Dental face bow assembly |
US5281133A (en) * | 1992-11-16 | 1994-01-25 | Ormco Corporation | Rapid palatal expansion device |
US5868138A (en) * | 1993-04-13 | 1999-02-09 | Silent Knight Ventures, Inc. | Dental appliance for treatment of snoring and obstructive sleep apnea |
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US5409017A (en) * | 1994-01-19 | 1995-04-25 | The University Of British Columbia | Mandible repositioning appliance |
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Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2438832A (en) * | 2006-04-04 | 2007-12-12 | Sleepworks Products Ltd | Device to reduce snoring and sleep apnoea by holding a wearer's jaw in the correct position |
GB2438832B (en) * | 2006-04-04 | 2009-03-04 | Sleepworks Products Ltd | Device to reduce snoring and sleep apnoea |
WO2007113465A1 (en) * | 2006-04-04 | 2007-10-11 | Sleepworks Products Ltd | Device to reduce snoring and sleep apnoea |
AU2008253589B2 (en) * | 2007-05-17 | 2014-02-20 | Airospace Enterprises Pty Ltd | Mandibular advancement device |
WO2008141372A1 (en) * | 2007-05-17 | 2008-11-27 | Michael Stubbs | Mandibular advancement device |
WO2009049602A1 (en) * | 2007-10-19 | 2009-04-23 | Schmitt-Bylandt Juergen | System for mandibular protrusion to prevent snoring and apnea |
DE102008007281A1 (en) | 2008-02-02 | 2009-08-06 | Rainer Hamann | Intraoral therapy device for prevention of snoring and obstructive sleep apnea, is designed for forward displacement of mandible relative to maxilla and extension of rear throat, and guide element is mounted before tooth rows of jaw shell |
WO2010003198A2 (en) * | 2008-07-07 | 2010-01-14 | Jozef Frans Nelissen | Device for treating night time breathing problems |
WO2010003198A3 (en) * | 2008-07-07 | 2010-05-14 | Jozef Frans Nelissen | Device for treating night time breathing problems |
BE1018209A5 (en) * | 2008-07-07 | 2010-07-06 | Nelissen Jozef Frans | DEVICE FOR TREATING NIGHT-BREATHING RESPIRATORY PROBLEMS. |
US8517029B2 (en) | 2008-07-07 | 2013-08-27 | Jozef Frans Nelissen | Device for treating night time breathing problems |
AU2009267736B2 (en) * | 2008-07-07 | 2014-05-15 | Jozef Frans Nelissen | Device for treating night time breathing problems |
DE102012003564B3 (en) * | 2012-02-23 | 2013-06-20 | Bernd Scheffel | Device for improving the breathing of a person |
EP2630938A1 (en) | 2012-02-23 | 2013-08-28 | Bernd Scheffel | Device for improving the respiration of a person |
DE102016001977A1 (en) | 2015-02-24 | 2016-08-25 | Fahri Yildiz | Infinitely adjustable lower jaw protrusion splint for the treatment of snoring and obstructive sleep apnea |
CN113143406A (en) * | 2020-12-14 | 2021-07-23 | 南通市肿瘤医院 | Tumour clamping device for oral and maxillofacial surgery |
Also Published As
Publication number | Publication date |
---|---|
JP2007501641A (en) | 2007-02-01 |
CA2535112A1 (en) | 2005-02-17 |
WO2005013867A3 (en) | 2005-06-30 |
WO2005013867B1 (en) | 2005-08-18 |
BE1015642A3 (en) | 2005-07-05 |
US20080135056A1 (en) | 2008-06-12 |
JP4709146B2 (en) | 2011-06-22 |
CA2535112C (en) | 2013-07-09 |
DK1659998T3 (en) | 2009-02-23 |
US7832402B2 (en) | 2010-11-16 |
ES2311841T3 (en) | 2009-02-16 |
EP1659998A2 (en) | 2006-05-31 |
EP1659998B1 (en) | 2008-10-22 |
DE602004017331D1 (en) | 2008-12-04 |
AU2004262450B2 (en) | 2009-07-30 |
AU2004262450A1 (en) | 2005-02-17 |
ATE411786T1 (en) | 2008-11-15 |
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