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Materials and methods for near-infrared and infrared lymph node mapping

Info

Publication number
WO2005001906A3
WO2005001906A3 PCT/US2004/005529 US2004005529W WO2005001906A3 WO 2005001906 A3 WO2005001906 A3 WO 2005001906A3 US 2004005529 W US2004005529 W US 2004005529W WO 2005001906 A3 WO2005001906 A3 WO 2005001906A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
infrared
near
imaged
methods
lymph
Prior art date
Application number
PCT/US2004/005529
Other languages
French (fr)
Other versions
WO2005001906A2 (en )
Inventor
John V Frangioni
Moungi G Bawendi
Sungjee Kim
Yong Taik Lim
Original Assignee
Massachusetts Inst Technology
Beth Israel Hospital
John V Frangioni
Moungi G Bawendi
Sungjee Kim
Yong Taik Lim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0065Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
    • A61K49/0067Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle quantum dots, fluorescent nanocrystals
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/813Of specified inorganic semiconductor composition, e.g. periodic table group IV-VI compositions
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/84Manufacture, treatment, or detection of nanostructure
    • Y10S977/88Manufacture, treatment, or detection of nanostructure with arrangement, process, or apparatus for testing
    • Y10S977/881Microscopy or spectroscopy, e.g. sem, tem
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/932Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/949Radiation emitter using nanostructure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/932Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953Detector using nanostructure
    • Y10S977/954Of radiant energy

Abstract

A lymphatic system can be imaged with emissive semiconductor nanocrystals, for example, in the near infrared.
PCT/US2004/005529 2003-03-04 2004-02-26 Materials and methods for near-infrared and infrared lymph node mapping WO2005001906A3 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US45124603 true 2003-03-04 2003-03-04
US60/451,246 2003-03-04
US10772425 US7181266B2 (en) 2003-03-04 2004-02-06 Materials and methods for near-infrared and infrared lymph node mapping
US10/772,425 2004-02-06

Publications (2)

Publication Number Publication Date
WO2005001906A2 true WO2005001906A2 (en) 2005-01-06
WO2005001906A3 true true WO2005001906A3 (en) 2005-12-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/005529 WO2005001906A3 (en) 2003-03-04 2004-02-26 Materials and methods for near-infrared and infrared lymph node mapping

Country Status (2)

Country Link
US (1) US7181266B2 (en)
WO (1) WO2005001906A3 (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6607829B1 (en) * 1997-11-13 2003-08-19 Massachusetts Institute Of Technology Tellurium-containing nanocrystalline materials
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
EP1442483A2 (en) * 2001-10-29 2004-08-04 Technion Research and Development of Foundation Ltd. Near infra-red composite polymer-nanocrystal materials and electro-optical devices produced therefrom
US20050020922A1 (en) * 2003-03-04 2005-01-27 Frangioni John V. Materials and methods for near-infrared and infrared intravascular imaging
US7190264B2 (en) * 2004-03-05 2007-03-13 Simon Fraser University Wireless computer monitoring device with automatic arming and disarming
CN1232608C (en) * 2004-04-06 2005-12-21 中国科学院长春应用化学研究所 Method for synthesizing nano semiconductor luminescence material on liquid-liquid interface
WO2005101530A1 (en) 2004-04-19 2005-10-27 Edward Sargent Optically-regulated optical emission using colloidal quantum dot nanocrystals
US7229690B2 (en) * 2004-07-26 2007-06-12 Massachusetts Institute Of Technology Microspheres including nanoparticles
CN100595564C (en) 2004-07-30 2010-03-24 百维吉伦特系统有限公司 Pathogen and particle detector system and method
WO2006042233A9 (en) * 2004-10-08 2006-06-29 Cleveland Clinic Foundation Medical imaging using quantum dots
US7746681B2 (en) * 2005-01-07 2010-06-29 Invisage Technologies, Inc. Methods of making quantum dot films
US7742322B2 (en) * 2005-01-07 2010-06-22 Invisage Technologies, Inc. Electronic and optoelectronic devices with quantum dot films
US7773404B2 (en) 2005-01-07 2010-08-10 Invisage Technologies, Inc. Quantum dot optical devices with enhanced gain and sensitivity and methods of making same
CA2519608A1 (en) 2005-01-07 2006-07-07 Edward Sargent Quantum dot-polymer nanocomposite photodetectors and photovoltaics
US8134175B2 (en) 2005-01-11 2012-03-13 Massachusetts Institute Of Technology Nanocrystals including III-V semiconductors
US7811479B2 (en) * 2005-02-07 2010-10-12 The Trustees Of The University Of Pennsylvania Polymer-nanocrystal quantum dot composites and optoelectronic devices
US7725169B2 (en) * 2005-04-15 2010-05-25 The Board Of Trustees Of The University Of Illinois Contrast enhanced spectroscopic optical coherence tomography
EP1907818A4 (en) * 2005-07-15 2012-03-14 Biovigilant Systems Inc Pathogen and particle detector system and method
WO2007054846A3 (en) * 2005-11-10 2007-09-27 Philips Intellectual Property Absorption and scattering map reconstruction for optical fluorescence tomography
US20090155182A1 (en) * 2005-12-09 2009-06-18 Invitrogen Corporation Optical in vivo imaging contrast agents and methods of use
WO2007090147A3 (en) * 2006-01-31 2008-08-07 Steven G Adie Method and apparatus for measurement of optical properties in tissue
US20080154102A1 (en) * 2006-07-03 2008-06-26 Frangioni John V Intraoperative imaging methods
US20080050316A1 (en) * 2006-08-24 2008-02-28 Baylor College Of Medicine Molecular imaging of epithelial cells in lymph
WO2008025005A3 (en) * 2006-08-24 2009-04-30 Baylor College Medicine Method of measuring propulsion in lymphatic structures
WO2008023305A3 (en) * 2006-08-25 2008-10-16 Koninkl Philips Electronics Nv Contrast agent comprising a tm2+ containing luminescent substance for optical imaging
US8003021B2 (en) * 2007-11-08 2011-08-23 Toyota Motor Engineering And Manufacturing North America, Inc. Synthesis of Pb alloy and core/shell nanowires
US8628976B2 (en) * 2007-12-03 2014-01-14 Azbil BioVigilant, Inc. Method for the detection of biologic particle contamination
US7751057B2 (en) 2008-01-18 2010-07-06 The Board Of Trustees Of The University Of Illinois Magnetomotive optical coherence tomography
US8115934B2 (en) 2008-01-18 2012-02-14 The Board Of Trustees Of The University Of Illinois Device and method for imaging the ear using optical coherence tomography
US8983580B2 (en) 2008-01-18 2015-03-17 The Board Of Trustees Of The University Of Illinois Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors
CA2719839C (en) * 2008-03-25 2017-08-22 Visen Medical, Inc. Animal holder for in vivo tomographic imaging with multiple modalities
WO2010017634A1 (en) * 2008-08-12 2010-02-18 National Research Council Of Canada Colloidal nanocrystal ensembles with narrow linewidth band gap photoluminescence and methods of synthesizing colloidal semiconductor nanocrystals
US8637082B2 (en) 2008-10-03 2014-01-28 Life Technologies Corporation Methods for preparation of ZnTe nanocrystals
GB0901226D0 (en) * 2009-01-26 2009-03-11 Sharp Kk Fabrication of nitride nanoparticles
GB0901225D0 (en) 2009-01-26 2009-03-11 Sharp Kk Nitride nanoparticles
KR101065241B1 (en) 2009-05-13 2011-09-19 한국과학기술연구원 Nanoparticles of emissive polymers and preparation method thereof
US9011818B2 (en) * 2009-11-30 2015-04-21 Massachusetts Institute Of Technology Materials and methods for biological imaging
US9151668B1 (en) * 2011-01-12 2015-10-06 Radiation Monitoring Devices, Inc. Quantum dot radiation detection, systems and methods
US8508830B1 (en) 2011-05-13 2013-08-13 Google Inc. Quantum dot near-to-eye display
US9443061B2 (en) 2011-08-16 2016-09-13 Elwha Llc Devices and methods for recording information on a subject's body
US9286615B2 (en) 2011-08-16 2016-03-15 Elwha Llc Devices and methods for recording information on a subject's body
US9772270B2 (en) 2011-08-16 2017-09-26 Elwha Llc Devices and methods for recording information on a subject's body
WO2014081419A3 (en) * 2012-11-20 2015-06-11 The Board Of Trustees Of The Leland Stanford Junior University High resolution imaging using near-infrared-ii fluorescence
US20150273085A1 (en) * 2013-04-22 2015-10-01 Massachusetts Institute Of Technology Short-wavelength infrared (swir) fluorescence in vivo and intravital imaging with semiconductor nanocrystals
US20170062645A1 (en) * 2013-05-09 2017-03-02 Meir Israelowitz Method for producing biomimetic-inspired infrared sensors from zinc phosphide microwires

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5101827A (en) * 1985-07-05 1992-04-07 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US6207229B1 (en) * 1997-11-13 2001-03-27 Massachusetts Institute Of Technology Highly luminescent color-selective materials and method of making thereof
US6444192B1 (en) * 1999-02-05 2002-09-03 The Regents Of The University Of California Diagnostic imaging of lymph structures
US6633370B2 (en) * 2000-03-07 2003-10-14 Spectra Science Corporation Quantum dots, semiconductor nanocrystals and semiconductor particles used as fluorescent coding elements
US6819692B2 (en) * 2000-03-14 2004-11-16 Massachusetts Institute Of Technology Optical amplifiers and lasers

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2101827A (en) * 1928-08-27 1937-12-07 Gen Motors Corp Synchronized power transmission mechanism
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions
US5262357A (en) * 1991-11-22 1993-11-16 The Regents Of The University Of California Low temperature thin films formed from nanocrystal precursors
EP0613585A4 (en) * 1991-11-22 1995-06-21 Univ California Semiconductor nanocrystals covalently bound to solid inorganic surfaces using self-assembled monolayers.
US5505928A (en) * 1991-11-22 1996-04-09 The Regents Of University Of California Preparation of III-V semiconductor nanocrystals
US5674698A (en) * 1992-09-14 1997-10-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US6048616A (en) * 1993-04-21 2000-04-11 Philips Electronics N.A. Corp. Encapsulated quantum sized doped semiconductor particles and method of manufacturing same
US6159445A (en) * 1994-07-20 2000-12-12 Nycomed Imaging As Light imaging contrast agents
US5537000A (en) * 1994-04-29 1996-07-16 The Regents, University Of California Electroluminescent devices formed using semiconductor nanocrystals as an electron transport media and method of making such electroluminescent devices
US5677545A (en) * 1994-09-12 1997-10-14 Motorola Organic light emitting diodes with molecular alignment and method of fabrication
US5985353A (en) * 1994-12-01 1999-11-16 University Of Massachusetts Lowell Biomolecular synthesis of quantum dot composites
US5585640A (en) * 1995-01-11 1996-12-17 Huston; Alan L. Glass matrix doped with activated luminescent nanocrystalline particles
GB9518910D0 (en) * 1995-09-15 1995-11-15 Imperial College Process
US5876480A (en) * 1996-02-20 1999-03-02 The United States Of America As Represented By The Secretary Of The Navy Synthesis of unagglomerated metal nano-particles at membrane interfaces
JP4245664B2 (en) 1996-07-29 2009-03-25 ナノスフェアー インコーポレイテッド Method of detecting a target acid using gold nanoparticles having oligonucleotides
US5939021A (en) 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
US6165440A (en) * 1997-07-09 2000-12-26 Board Of Regents, The University Of Texas System Radiation and nanoparticles for enhancement of drug delivery in solid tumors
EP1034234B1 (en) * 1997-10-28 2003-07-16 The University Of Melbourne Stabilized particles and methods of preparation and use thereof
US6607829B1 (en) * 1997-11-13 2003-08-19 Massachusetts Institute Of Technology Tellurium-containing nanocrystalline materials
US5985173A (en) * 1997-11-18 1999-11-16 Gray; Henry F. Phosphors having a semiconductor host surrounded by a shell
US6207392B1 (en) * 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6139585A (en) * 1998-03-11 2000-10-31 Depuy Orthopaedics, Inc. Bioactive ceramic coating and method
US6501091B1 (en) * 1998-04-01 2002-12-31 Massachusetts Institute Of Technology Quantum dot white and colored light emitting diodes
US6337117B1 (en) * 1998-07-01 2002-01-08 Mitsubishi Chemical Corporation Optical memory device
US6251303B1 (en) * 1998-09-18 2001-06-26 Massachusetts Institute Of Technology Water-soluble fluorescent nanocrystals
US6326144B1 (en) * 1998-09-18 2001-12-04 Massachusetts Institute Of Technology Biological applications of quantum dots
US6306610B1 (en) * 1998-09-18 2001-10-23 Massachusetts Institute Of Technology Biological applications of quantum dots
JP2000104058A (en) * 1998-09-28 2000-04-11 Sony Corp Production of luminescent material
WO2000028598A1 (en) * 1998-11-10 2000-05-18 Biocrystal Limited Methods for identification and verification
WO2000027365A9 (en) 1998-11-24 2000-11-23 Biocrystal Ltd Functionalized nanocrystals and their use in detection systems
WO2000027436A1 (en) 1998-11-10 2000-05-18 Biocrystal Limited Functionalized nanocrystals as visual tissue-specific imaging agents, and methods for fluorescence imaging
WO2000028089A1 (en) 1998-11-10 2000-05-18 Biocrystal Limited Functionalized nanocrystals and their use in labeling for strand synthesis or sequence determination
US6114038A (en) * 1998-11-10 2000-09-05 Biocrystal Ltd. Functionalized nanocrystals and their use in detection systems
US6261779B1 (en) 1998-11-10 2001-07-17 Bio-Pixels Ltd. Nanocrystals having polynucleotide strands and their use to form dendrimers in a signal amplification system
US6410255B1 (en) * 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
US6167297A (en) * 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
WO2001012071A1 (en) * 1999-08-13 2001-02-22 Point Biomedical Corporation Microparticles useful as ultrasonic contrast agents and for lymphatic system
EP1088559A3 (en) * 1999-09-29 2002-10-02 INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN Galenic formulations
US6530944B2 (en) * 2000-02-08 2003-03-11 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
JP2001299676A (en) * 2000-04-25 2001-10-30 Fuji Photo Film Co Ltd Method and system for detecting sentinel lymph node
JP2002095663A (en) * 2000-09-26 2002-04-02 Fuji Photo Film Co Ltd Method of acquiring optical tomographic image of sentinel lymph node and its device
EP1337695B1 (en) * 2000-10-04 2010-12-08 The Board Of Trustees Of The University Of Arkansas Synthesis of colloidal metal chalcogenide nanocrystals
JP4567436B2 (en) * 2001-07-20 2010-10-20 ライフ テクノロジーズ コーポレーション Luminescent nanoparticles and methods for their preparation
JP2005502176A (en) * 2001-09-04 2005-01-20 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィKoninklijke Philips Electronics N.V. Electroluminescent device having a quantum dot
WO2003038401A3 (en) * 2001-10-31 2003-07-17 Univ California Semiconductor nanocrystal-based cellular imaging
US7189417B2 (en) * 2002-05-01 2007-03-13 The Trustees Of The University Of Pennsylvania Nanometer-sized carrier medium
JP2004077389A (en) * 2002-08-21 2004-03-11 Hitachi Software Eng Co Ltd Functional fluorescent reagent containing semiconductor nanoparticle
DK1593091T3 (en) * 2003-01-25 2013-10-28 Seno Medical Instr Inc Acousto-optic imaging with high contrast by the use of non-spherical nanoparticles
US20050020922A1 (en) * 2003-03-04 2005-01-27 Frangioni John V. Materials and methods for near-infrared and infrared intravascular imaging
US20050220714A1 (en) * 2004-04-01 2005-10-06 Susan Kauzlarich Agents for use in magnetic resonance and optical imaging

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5101827A (en) * 1985-07-05 1992-04-07 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US6207229B1 (en) * 1997-11-13 2001-03-27 Massachusetts Institute Of Technology Highly luminescent color-selective materials and method of making thereof
US6444192B1 (en) * 1999-02-05 2002-09-03 The Regents Of The University Of California Diagnostic imaging of lymph structures
US6633370B2 (en) * 2000-03-07 2003-10-14 Spectra Science Corporation Quantum dots, semiconductor nanocrystals and semiconductor particles used as fluorescent coding elements
US6819692B2 (en) * 2000-03-14 2004-11-16 Massachusetts Institute Of Technology Optical amplifiers and lasers

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US7181266B2 (en) 2007-02-20 grant
WO2005001906A2 (en) 2005-01-06 application
US20050020923A1 (en) 2005-01-27 application

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