WO2004081186A8 - Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof - Google Patents

Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof

Info

Publication number
WO2004081186A8
WO2004081186A8 PCT/US2004/007140 US2004007140W WO2004081186A8 WO 2004081186 A8 WO2004081186 A8 WO 2004081186A8 US 2004007140 W US2004007140 W US 2004007140W WO 2004081186 A8 WO2004081186 A8 WO 2004081186A8
Authority
WO
WIPO (PCT)
Prior art keywords
methods
stenosis
detection
single nucleotide
nucleotide polymorphisms
Prior art date
Application number
PCT/US2004/007140
Other languages
French (fr)
Other versions
WO2004081186A2 (en
WO2004081186A3 (en
Inventor
Michele Cargill
James J Devlin
May M Luke
Original Assignee
Applera Corp
Michele Cargill
James J Devlin
May M Luke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp, Michele Cargill, James J Devlin, May M Luke filed Critical Applera Corp
Priority to JP2006506981A priority Critical patent/JP2009521904A/en
Priority to EP04737312A priority patent/EP1613774A2/en
Priority to CA002518956A priority patent/CA2518956A1/en
Publication of WO2004081186A2 publication Critical patent/WO2004081186A2/en
Publication of WO2004081186A8 publication Critical patent/WO2004081186A8/en
Publication of WO2004081186A3 publication Critical patent/WO2004081186A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention is based on the discovery of single nucleotide polymorphisms (SNPs) that are associated with stenosis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
PCT/US2004/007140 2003-03-10 2004-03-10 Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof WO2004081186A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2006506981A JP2009521904A (en) 2003-03-10 2004-03-10 Single nucleotide polymorphism associated with stenosis, detection method and use thereof
EP04737312A EP1613774A2 (en) 2003-03-10 2004-03-10 Genetic polymorphisms associated with stenosis, methods of detection and uses thereof
CA002518956A CA2518956A1 (en) 2003-03-10 2004-03-10 Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45305003P 2003-03-10 2003-03-10
US60/453,050 2003-03-10
US46643703P 2003-04-30 2003-04-30
US60/466,437 2003-04-30

Publications (3)

Publication Number Publication Date
WO2004081186A2 WO2004081186A2 (en) 2004-09-23
WO2004081186A8 true WO2004081186A8 (en) 2005-01-20
WO2004081186A3 WO2004081186A3 (en) 2005-10-20

Family

ID=32994473

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/007140 WO2004081186A2 (en) 2003-03-10 2004-03-10 Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof

Country Status (5)

Country Link
US (1) US7625699B2 (en)
EP (1) EP1613774A2 (en)
JP (1) JP2009521904A (en)
CA (1) CA2518956A1 (en)
WO (1) WO2004081186A2 (en)

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JP5590697B2 (en) * 2005-03-11 2014-09-17 セレラ コーポレーション Genetic polymorphism associated with coronary heart disease, detection method and use thereof
US7977052B2 (en) 2005-03-11 2011-07-12 Celera Corporation Genetic polymorphisms associated with coronary heart disease, methods of detection and uses thereof
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WO2007028147A2 (en) * 2005-09-01 2007-03-08 Philadelphia Health & Education Corporation D.B.A. Drexel University College Of Medicin Identification of a prostatic intraepithelial neoplasia (pin)-specific gene and protein (pin-1) useful as a diagnostic treatment for prostate cancer
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Also Published As

Publication number Publication date
WO2004081186A2 (en) 2004-09-23
CA2518956A1 (en) 2004-09-23
EP1613774A2 (en) 2006-01-11
US20070031847A1 (en) 2007-02-08
JP2009521904A (en) 2009-06-11
US7625699B2 (en) 2009-12-01
WO2004081186A3 (en) 2005-10-20

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