WO2004069130A1 - A machine for the treatment of pharmaceutical products - Google Patents

A machine for the treatment of pharmaceutical products Download PDF

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Publication number
WO2004069130A1
WO2004069130A1 PCT/IB2004/000296 IB2004000296W WO2004069130A1 WO 2004069130 A1 WO2004069130 A1 WO 2004069130A1 IB 2004000296 W IB2004000296 W IB 2004000296W WO 2004069130 A1 WO2004069130 A1 WO 2004069130A1
Authority
WO
WIPO (PCT)
Prior art keywords
pan
opening
products
treated
machine according
Prior art date
Application number
PCT/IB2004/000296
Other languages
French (fr)
Inventor
Roberto Trebbi
Original Assignee
I.M.A. Industria Macchine Automatiche S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by I.M.A. Industria Macchine Automatiche S.P.A. filed Critical I.M.A. Industria Macchine Automatiche S.P.A.
Priority to JP2006502402A priority Critical patent/JP2006516918A/en
Priority to US10/542,954 priority patent/US7395777B2/en
Priority to EP04707587A priority patent/EP1589927B1/en
Priority to BR0407119-0A priority patent/BRPI0407119A/en
Priority to KR1020057013995A priority patent/KR101156258B1/en
Publication of WO2004069130A1 publication Critical patent/WO2004069130A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B13/00—Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups B05B1/00 - B05B11/00
    • B05B13/02—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work
    • B05B13/0221—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts
    • B05B13/025—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts the objects or work being present in bulk
    • B05B13/0257—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts the objects or work being present in bulk in a moving container, e.g. a rotatable foraminous drum
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/02—Apparatus specially adapted for manufacture or treatment of sweetmeats or confectionery; Accessories therefor
    • A23G3/20—Apparatus for coating or filling sweetmeats or confectionery
    • A23G3/26—Apparatus for coating by tumbling with a liquid or powder, spraying device-associated, drum, rotating pan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/12—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating drums

Definitions

  • the present invention relates to a machine for the treatment of products, in particular pharmaceutical products.
  • the invention relates to a coating machine used to apply a coating to pharmaceutical products, such as tablets or capsules, to which the present specification refers but without thereby restricting the scope of the invention.
  • a conventional machine for coating pharmaceutical products comprises a hollow pan that revolves about a horizontal axis and is known in the trade by the term "Pellegrini coating pan", which will herein be referred to simply as “coating pan”.
  • the coating pan has a central, circular opening through which the pharmaceutical products are fed into the pan from a reservoir, and a plurality of nozzles, mounted on an arm extending in a direction substantially parallel to the axis of rotation of the pan and designed to spray a coating liquid towards and over a mass of pharmaceutical products to be treated, lying centrally inside the pan and coming from the reservoir through the central opening.
  • the inside walls of the coating pan are preferably equipped with a plurality of inclined baffles protruding radially from the walls themselves. These baffles facilitate uniform distribution of the mass of products not only while the coating pan rotates clockwise about its axis as the products to be treated are fed into it but also while the coating pan rotates in the opposite direction as the treated product is fed out of the coating pan into a container placed at the central opening beforehand.
  • a major drawback in a coating machine of this kind is that the pan has a single opening for infeed of the untreated product still to be treated, as well as for outfeed of the treated product. This creates a potential risk of contamination between incoming and outgoing products, especially when there is a change to a different type of coating material.
  • the present invention has for an object to provide a machine for treating pharmaceutical products that overcomes the above mentioned drawback.
  • Another object of the present invention is to provide a coating machine that makes the treatment of the pharmaceutical products as safe and rational as possible and that also permits rapid cleaning and sterilising of the coating pan.
  • the invention accordingly provides a machine for the treatment of pharmaceutical products, comprising a pan that revolves about an axis of rotation and a dispensing unit designed to disperse a coating material inside the pan over a mass of the products located in the pan; the machine being characterised in that the pan has an opening for feeding the products to be treated into the pan, and an opening for feeding the products already treated with the coating material out of the pan, the infeed opening and the outfeed opening being separate and independent of each other; a portion of the inside surface of the pan being equipped with at least one helical flow regulating fin designed to facilitate inflow of the products to be treated into the pan during the feeding of the products into the pan through the infeed opening when the pan itself revolves in a first direction of rotation, and to cause outflow of the treated products from the pan during the outfeed of the treated products from the pan through the outfeed opening when the pan itself revolves in a second direction of rotation, opposite to the first direction of rotation.
  • Figure 1 is a side view, partly in cross section and with some parts cut away for clarity, of a preferred embodiment of the machine according to the invention for the treatment of products;
  • Figure 2 is a schematic front view of a detail from the machine of Figure 1;
  • Figure 3 is a plane vertical section of the detail of Figure 2.
  • the numeral 100 denotes in its entirety a machine for coating pharmaceutical products P, such as, for example, tablets or capsules.
  • the machine 100 comprises a supporting frame 1, a pan 2 mounted on the supporting frame 1 in such a way that it can be rotationally driven about an axis X by a customary motor, which is not illustrated, and a dispensing unit 3 which, during use, is positioned inside the pan 2 in order to dispense and disperse, preferably by spraying, a coating liquid over a mass M of products P located in a substantially central zone Z inside the pan 2.
  • a substantially truncated cone shaped front portion K of the inside surface of the pan 2 is equipped with first, second and third flow regulating fins 4, 5, and 6, which are preferably equally spaced and defined by cuspate profiles with triangular cross sections whose base is joined smoothly to the inside surface of the pan 2, and which extend in sequence along the truncated cone shaped portion of the inside surface in a substantially helical direction.
  • the first, second and third flow regulating fins 4, 5 and 6 are designed to facilitate inflow towards the zone Z of the pan 2 (in the direction indicated by the arrow F3 in Figures 2 and 3) of the untreated product P fed through a first infeed opening or inlet 7 of the pan 2 while the pan 2 revolves about the axis X in a first direction of rotation Fl (clockwise in Figure 2), and to cause outflow (in the direction indicated by the arrow F4 in Figures 2 and 3) of the treated or coated product PT towards the outside of the pan 2, through an outfeed opening or outlet 8, located below the infeed opening 7 in a position separate and independent of the latter, while the pan 2 itself revolves about the axis X in a second direction of rotation F2 (anti-clockwise in
  • the dispensing device 3 comprises a plurality of nozzles 3u appropriately directed inside the pan 2 to cover the zone Z .
  • the nozzles 3u are mounted on a horizontal arm 3b, substantially parallel to the axis of rotation X of the pan 2 and protruding from the pan 2.
  • conduits for supplying the coating liquid are connected to a feed tank (of customary type and therefore not illustrated) located outside the pan 2.
  • the outfeed opening 8 has the shape of a ring made on a circumferential area of the pan 2 and being larger in diameter than the circumferential area on which the infeed opening 7, also having the shape of a ring, is made, so that the infeed opening 7 is positioned above and to one side of the outfeed opening 8.
  • the outfeed opening 8 is connected to a conduit 9, made under the infeed opening 7 with respect to a horizontal plane of the coating machine 100, on a protrusion 12 of the frame 1, and defines a tubular channel through which the products PT from the outfeed opening 8 are conveyed to the outside.
  • the tubular conduit 9 is equipped with a shutoff valve 14 that seals the outside end of the conduit 9 itself.
  • the infeed opening 7 comprises an access conduit
  • the conduit 11 leads onto an inclined surface 13 ( Figure 3) that extends to an area close to the inside of the pan 2 and partially covers the outfeed opening 8.
  • the conduit 11 is also equipped with a shutoff valve 15 that seals the outside end of the conduit 11 itself.
  • the two conduits 11 and 9 are connected to separate reservoirs 16 and 17 (shown schematically by the dashed lines in Figure 1) for feeding the product to be treated P and collecting the treated product PT, respectively.
  • close to the outfeed opening 8 there is a guide element 10 that is joined smoothly to the profile of each fin 4, 5 and 6, for feeding out the treated product PT.
  • At least three guide elements 10 separated from each other by equal angular intervals ⁇ and each consisting of a chute facing the outfeed opening 8.
  • the three guide elements 10 are separated from each other by equal angular intervals of approximately 120°.
  • the area adjacent to the treated product PT outfeed opening 8, close to the product P infeed area, is partly covered by the inclined surface 13: this architecture keeps the openings 7 and 8 well isolated from each other during the steps of feeding in the product to be treated P and of feeding out the treated product PT, thus eliminating the risk of contamination between the incoming products P and the coated products PT feeding out of the pan 2 of the machine 100.
  • the machine constructed as described above therefore achieves the aforementioned aims thanks to its extremely simple structure, with a rapid production cycle made possible by two independent reservoirs, one for feeding the product in and the other for collecting the treated product fed out.
  • the machine 100 can advantageously perform cycles for cleaning or sterilising the inside surface of the pan while the pan itself continues to revolve. This is made possible by the fact that the conduits leading into and out of the pan can be sealed off and are totally independent of and separate from each other. This saves considerable time between one production cycle and the next.
  • Other advantages are derived from the constructional architecture of the fins, which have triangular cuspate profiles with smooth, rounded edges which facilitate product flow and prevent product accumulations or "shadow areas", that is to say, parts of the inside surface of the pan where the coating liquid is not properly dispersed.

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Coating Apparatus (AREA)
  • Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)

Abstract

A machine (100) for the treatment of pharmaceutical products (P) comprises a pan (2) that revolves about an axis of rotation (X) and a dispensing unit (3) designed to disperse a coating material inside the pan (2) over a mass (M) of the products (P) located in the pan (2). The pan (2) has an opening (7) for feeding the products to be treated (P) into the pan (2), and an opening (8) for feeding the products (PT) already treated with the coating material out of the pan (2), the infeed opening (7) and the outfeed opening (8) being separate and independent of each other. A portion (K) of the inside surface of the pan (2) is equipped with at least one helical flow regulating fin (4, 5, 6) designed to facilitate inflow (F3) of the products to be treated (P) into the pan (2) during the feeding of the products (P) into the pan (2) through the infeed opening (7) when the pan (2) itself revolves in a first direction of rotation (Fl), and to cause outflow (F4) of the treated products (PT) from the pan (2) during the outfeed of the treated products (PT) from the pan (2) through the outfeed opening (8) when the pan (2) itself revolves in a second direction of rotation (F2), opposite to the first direction of rotation (F1).

Description

Description
A machine for the treatment of pharmaceutical products
Technical Field
The present invention relates to a machine for the treatment of products, in particular pharmaceutical products.
In particular, the invention relates to a coating machine used to apply a coating to pharmaceutical products, such as tablets or capsules, to which the present specification refers but without thereby restricting the scope of the invention.
Background Art At present, a conventional machine for coating pharmaceutical products comprises a hollow pan that revolves about a horizontal axis and is known in the trade by the term "Pellegrini coating pan", which will herein be referred to simply as "coating pan". At the front of it, the coating pan has a central, circular opening through which the pharmaceutical products are fed into the pan from a reservoir, and a plurality of nozzles, mounted on an arm extending in a direction substantially parallel to the axis of rotation of the pan and designed to spray a coating liquid towards and over a mass of pharmaceutical products to be treated, lying centrally inside the pan and coming from the reservoir through the central opening.
At present, the inside walls of the coating pan are preferably equipped with a plurality of inclined baffles protruding radially from the walls themselves. These baffles facilitate uniform distribution of the mass of products not only while the coating pan rotates clockwise about its axis as the products to be treated are fed into it but also while the coating pan rotates in the opposite direction as the treated product is fed out of the coating pan into a container placed at the central opening beforehand.
A major drawback in a coating machine of this kind is that the pan has a single opening for infeed of the untreated product still to be treated, as well as for outfeed of the treated product. This creates a potential risk of contamination between incoming and outgoing products, especially when there is a change to a different type of coating material. The present invention has for an object to provide a machine for treating pharmaceutical products that overcomes the above mentioned drawback.
Another object of the present invention is to provide a coating machine that makes the treatment of the pharmaceutical products as safe and rational as possible and that also permits rapid cleaning and sterilising of the coating pan.
Disclosure of the invention
The invention accordingly provides a machine for the treatment of pharmaceutical products, comprising a pan that revolves about an axis of rotation and a dispensing unit designed to disperse a coating material inside the pan over a mass of the products located in the pan; the machine being characterised in that the pan has an opening for feeding the products to be treated into the pan, and an opening for feeding the products already treated with the coating material out of the pan, the infeed opening and the outfeed opening being separate and independent of each other; a portion of the inside surface of the pan being equipped with at least one helical flow regulating fin designed to facilitate inflow of the products to be treated into the pan during the feeding of the products into the pan through the infeed opening when the pan itself revolves in a first direction of rotation, and to cause outflow of the treated products from the pan during the outfeed of the treated products from the pan through the outfeed opening when the pan itself revolves in a second direction of rotation, opposite to the first direction of rotation.
Description of the drawings The technical characteristics of the invention are clearly described in the claims below and its advantages are apparent from the detailed description which follows, with reference to the accompanying drawings which illustrate a preferred embodiment of the invention provided merely by way of example without restricting the scope of the inventive concept, and in which:
Figure 1 is a side view, partly in cross section and with some parts cut away for clarity, of a preferred embodiment of the machine according to the invention for the treatment of products;
Figure 2 is a schematic front view of a detail from the machine of Figure 1; and
Figure 3 is a plane vertical section of the detail of Figure 2.
Detailed description of the preferred embodiments of the invention
With reference to Figure 1, the numeral 100 denotes in its entirety a machine for coating pharmaceutical products P, such as, for example, tablets or capsules.
The machine 100 comprises a supporting frame 1, a pan 2 mounted on the supporting frame 1 in such a way that it can be rotationally driven about an axis X by a customary motor, which is not illustrated, and a dispensing unit 3 which, during use, is positioned inside the pan 2 in order to dispense and disperse, preferably by spraying, a coating liquid over a mass M of products P located in a substantially central zone Z inside the pan 2.
As illustrated in Figures 1, 2 and 3, a substantially truncated cone shaped front portion K of the inside surface of the pan 2 is equipped with first, second and third flow regulating fins 4, 5, and 6, which are preferably equally spaced and defined by cuspate profiles with triangular cross sections whose base is joined smoothly to the inside surface of the pan 2, and which extend in sequence along the truncated cone shaped portion of the inside surface in a substantially helical direction.
During use, the first, second and third flow regulating fins 4, 5 and 6 are designed to facilitate inflow towards the zone Z of the pan 2 (in the direction indicated by the arrow F3 in Figures 2 and 3) of the untreated product P fed through a first infeed opening or inlet 7 of the pan 2 while the pan 2 revolves about the axis X in a first direction of rotation Fl (clockwise in Figure 2), and to cause outflow (in the direction indicated by the arrow F4 in Figures 2 and 3) of the treated or coated product PT towards the outside of the pan 2, through an outfeed opening or outlet 8, located below the infeed opening 7 in a position separate and independent of the latter, while the pan 2 itself revolves about the axis X in a second direction of rotation F2 (anti-clockwise in
Figure 2), opposite to the first direction of rotation FI.
As shown in Figure 1, the dispensing device 3 comprises a plurality of nozzles 3u appropriately directed inside the pan 2 to cover the zone Z . The nozzles 3u are mounted on a horizontal arm 3b, substantially parallel to the axis of rotation X of the pan 2 and protruding from the pan 2.
Inside the arm 3b there are conduits for supplying the coating liquid, these conduits being connected to a feed tank (of customary type and therefore not illustrated) located outside the pan 2.
As illustrated in more detail in Figures 2 and 3, the outfeed opening 8 has the shape of a ring made on a circumferential area of the pan 2 and being larger in diameter than the circumferential area on which the infeed opening 7, also having the shape of a ring, is made, so that the infeed opening 7 is positioned above and to one side of the outfeed opening 8.
The outfeed opening 8 is connected to a conduit 9, made under the infeed opening 7 with respect to a horizontal plane of the coating machine 100, on a protrusion 12 of the frame 1, and defines a tubular channel through which the products PT from the outfeed opening 8 are conveyed to the outside.
The tubular conduit 9 is equipped with a shutoff valve 14 that seals the outside end of the conduit 9 itself. Similarly, the infeed opening 7 comprises an access conduit
11 made on the protrusion 12 and positioned above the conduit 9.
The conduit 11 leads onto an inclined surface 13 (Figure 3) that extends to an area close to the inside of the pan 2 and partially covers the outfeed opening 8. The conduit 11 is also equipped with a shutoff valve 15 that seals the outside end of the conduit 11 itself. Further, the two conduits 11 and 9 are connected to separate reservoirs 16 and 17 (shown schematically by the dashed lines in Figure 1) for feeding the product to be treated P and collecting the treated product PT, respectively. As shown in more detail in Figure 2, close to the outfeed opening 8 there is a guide element 10 that is joined smoothly to the profile of each fin 4, 5 and 6, for feeding out the treated product PT.
Preferably, there are at least three guide elements 10 separated from each other by equal angular intervals α and each consisting of a chute facing the outfeed opening 8.
More specifically, the three guide elements 10 are separated from each other by equal angular intervals of approximately 120°. As illustrated in Figure 3, the area adjacent to the treated product PT outfeed opening 8, close to the product P infeed area, is partly covered by the inclined surface 13: this architecture keeps the openings 7 and 8 well isolated from each other during the steps of feeding in the product to be treated P and of feeding out the treated product PT, thus eliminating the risk of contamination between the incoming products P and the coated products PT feeding out of the pan 2 of the machine 100.
The machine constructed as described above therefore achieves the aforementioned aims thanks to its extremely simple structure, with a rapid production cycle made possible by two independent reservoirs, one for feeding the product in and the other for collecting the treated product fed out.
Moreover, the machine 100 can advantageously perform cycles for cleaning or sterilising the inside surface of the pan while the pan itself continues to revolve. This is made possible by the fact that the conduits leading into and out of the pan can be sealed off and are totally independent of and separate from each other. This saves considerable time between one production cycle and the next. Other advantages are derived from the constructional architecture of the fins, which have triangular cuspate profiles with smooth, rounded edges which facilitate product flow and prevent product accumulations or "shadow areas", that is to say, parts of the inside surface of the pan where the coating liquid is not properly dispersed.
It will be understood that the coating machine described can be modified and adapted in several ways without thereby departing from the scope of the inventive concept. Moreover, all the details of the machine may be substituted by technically equivalent elements .

Claims

Claims
1. A machine (100) for the treatment of pharmaceutical products (P) comprising a pan (2) that revolves about an axis of rotation (X) and a dispensing unit (3) designed to disperse a coating material inside the pan (2) over a mass (M) of the products (P) located in the pan (2) ; the machine (100) being characterised in that the pan (2) has an opening (7) for feeding the products to be treated (P) into the pan (2), and an opening (8) for feeding the products (PT) already treated with the coating material out of the pan, the infeed opening (7) and the outfeed opening (8) being separate and independent of each other; a portion (K) of the inside surface of the pan (2) being equipped with at least one helical flow regulating fin (4, 5, 6) designed to facilitate inflow (F3) of the products to be treated (P) into the pan (2) during the feeding of the products (P) into the pan (2) through the infeed opening (7) when the pan (2) itself revolves in a first direction of rotation (FI) , and to cause outflow (F4) of the treated products (PT) from the pan (2) during the outfeed of the treated products (PT) from the pan (2) through the outfeed opening (8) when the pan (2) itself revolves in a second direction of rotation (F2) , opposite to the first direction of rotation (FI) .
2. The machine according to claim 1, characterised in that the infeed opening (7) in the pan (2) is located in a position above and to one side of the outfeed opening (8) .
3. The machine according to claim 1 or 2, characterised in that the flow regulating fin (4, 5, 6) has a substantially cuspate profile with a triangular cross section whose base is joined smoothly to the inside surface of the pan (2) .
4. The machine according to any of the foregoing claims from 1 to 3, characterised in that at the outfeed opening (8) there is at least one chute-like guide element (10) that is joined smoothly to the profile of the fin (4, 5, 6) .
5. The machine according to any of the foregoing claims from 1 to 4, characterised in that the flow regulating fins (4, 5, 6) on the portion (K) are equally spaced from each other.
6. The machine according to claims 4 and 5, characterised in that it comprises three chute-like guide elements (10) separated from each other by equal defined angular intervals (α) , each element (10) being joined smoothly to the profile of a respective flow regulating fin (4; 5; 6) .
7. The machine according to claim 6, characterised in that the three guide elements (10) are separated from each other by angular intervals (α) of approximately 120°.
8. The machine according to any of the foregoing claims from 1 to
7, characterised in that the infeed opening (7) comprises a conduit (11) for access from the outside, made on a protrusion (12) on the pan (2) and leading onto an inclined surface (13) that extends to an area close to the inside of the pan (2) and partially covers the outfeed opening (8) .
9. The machine according to any of the foregoing claims from 1 to
8, characterised in that the outfeed opening (8) comprises a tubular conduit (9) leading to the outside and made on a protrusion (12) of the pan (2) .
10. The machine according to claim 9, characterised in that the conduit (9) is equipped with a sealed shutoff valve (14) .
11. The machine according to any of the foregoing claims from 8 to 10, characterised in that the access conduit (11) is equipped with a sealed shutoff valve (15) .
12. The machine according to any of the foregoing claims from 1 to 11, characterised in that the infeed opening (7) and the outfeed opening (8) are connected to separate reservoirs (16, 17) for feeding the product to be treated (P) and collecting the treated product (PT) , respectively.
PCT/IB2004/000296 2003-02-06 2004-02-03 A machine for the treatment of pharmaceutical products WO2004069130A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2006502402A JP2006516918A (en) 2003-02-06 2004-02-03 Chemical processing machine
US10/542,954 US7395777B2 (en) 2003-02-06 2004-02-03 Machine for the treatment of pharmaceutical products
EP04707587A EP1589927B1 (en) 2003-02-06 2004-02-03 A machine for the treatment of pharmaceutical products
BR0407119-0A BRPI0407119A (en) 2003-02-06 2004-02-03 Pharmaceutical Treatment Machine
KR1020057013995A KR101156258B1 (en) 2003-02-06 2004-02-03 A machine for the treatment of pharmaceutical products

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000050A ITBO20030050A1 (en) 2003-02-06 2003-02-06 MACHINE FOR THE TREATMENT OF PHARMACEUTICAL PRODUCTS.
ITBO2003A000050 2003-02-06

Publications (1)

Publication Number Publication Date
WO2004069130A1 true WO2004069130A1 (en) 2004-08-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/000296 WO2004069130A1 (en) 2003-02-06 2004-02-03 A machine for the treatment of pharmaceutical products

Country Status (9)

Country Link
US (1) US7395777B2 (en)
EP (1) EP1589927B1 (en)
JP (1) JP2006516918A (en)
KR (1) KR101156258B1 (en)
CN (1) CN100522124C (en)
AR (1) AR043043A1 (en)
BR (1) BRPI0407119A (en)
IT (1) ITBO20030050A1 (en)
WO (1) WO2004069130A1 (en)

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IT201700047415A1 (en) * 2017-05-03 2018-11-03 Ima Spa Apparatus and Method for Coatings Bulk Material
CN112569116A (en) * 2020-12-11 2021-03-30 山东新马制药装备有限公司 High-closed multifunctional coating machine
JP7513241B2 (en) 2021-02-12 2024-07-09 フロイント産業株式会社 Sampling Device
CN115320903B (en) * 2022-10-14 2023-02-03 溧阳市宇峰新材料有限公司 Filling equipment for sealant and using method thereof
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BRPI0407119A (en) 2006-01-10
US20060124053A1 (en) 2006-06-15
EP1589927A1 (en) 2005-11-02
KR101156258B1 (en) 2012-06-13
JP2006516918A (en) 2006-07-13
ITBO20030050A1 (en) 2004-08-07
KR20050094473A (en) 2005-09-27
US7395777B2 (en) 2008-07-08
CN100522124C (en) 2009-08-05
AR043043A1 (en) 2005-07-13
CN1747707A (en) 2006-03-15

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