WO2004044122A3 - Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes - Google Patents
Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes Download PDFInfo
- Publication number
- WO2004044122A3 WO2004044122A3 PCT/IB2003/005252 IB0305252W WO2004044122A3 WO 2004044122 A3 WO2004044122 A3 WO 2004044122A3 IB 0305252 W IB0305252 W IB 0305252W WO 2004044122 A3 WO2004044122 A3 WO 2004044122A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- heteropolymeric
- nucleic acids
- complex
- sequence
- target
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003276602A AU2003276602A1 (en) | 2002-11-12 | 2003-09-24 | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/293,148 US7309569B2 (en) | 1999-12-21 | 2002-11-12 | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
US10/293,148 | 2002-11-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004044122A2 WO2004044122A2 (en) | 2004-05-27 |
WO2004044122A3 true WO2004044122A3 (en) | 2004-12-23 |
Family
ID=32312153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2003/005252 WO2004044122A2 (en) | 2002-11-12 | 2003-09-24 | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
Country Status (3)
Country | Link |
---|---|
US (1) | US7309569B2 (en) |
AU (1) | AU2003276602A1 (en) |
WO (1) | WO2004044122A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
EP1815010A2 (en) * | 2004-09-24 | 2007-08-08 | Ingeneus Inc. | Genomic assay |
WO2012122302A2 (en) | 2011-03-07 | 2012-09-13 | Oregon Health & Science University | Methods, apparatuses, and systems for detecting and quantifying phosphoproteins |
CN110308272B (en) * | 2013-03-13 | 2023-09-12 | 中尺度技术有限责任公司 | Improved assay method |
US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
WO2015175856A1 (en) | 2014-05-15 | 2015-11-19 | Meso Scale Technologies, Llc. | Improved assay methods |
CN114295594B (en) * | 2021-12-06 | 2023-09-19 | 贵州理工学院 | "turn on" type fluorescence sensor based on molecular beacon screening triple helix DNA intercalator |
Citations (4)
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US5800984A (en) * | 1990-12-17 | 1998-09-01 | Idexx Laboratories, Inc. | Nucleic acid sequence detection by triple helix formation at primer site in amplification reactions |
US5846729A (en) * | 1997-02-27 | 1998-12-08 | Lorne Park Research, Inc. | Assaying nucleotides in solution using a fluorescent intensity quenching effect |
US5874555A (en) * | 1987-10-30 | 1999-02-23 | California Institute Of Technology | Triple helices and processes for making same |
US6287772B1 (en) * | 1998-04-29 | 2001-09-11 | Boston Probes, Inc. | Methods, kits and compositions for detecting and quantitating target sequences |
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US4220450A (en) | 1978-04-05 | 1980-09-02 | Syva Company | Chemically induced fluorescence immunoassay |
FR2558172B1 (en) | 1984-01-16 | 1986-06-13 | Inst Nat Sante Rech Med | PROBE CONTAINING MODIFIED NUCLEIC ACID AND RECOGNITION BY SPECIFIC ANTIBODIES AND USE OF SUCH PROBE AND THESE SPECIFIC ANTIBODIES TO DETECT AND CHARACTERIZE A HOMOLOGATED DNA SEQUENCE |
US4876187A (en) | 1985-12-05 | 1989-10-24 | Meiogenics, Inc. | Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences |
US5011769A (en) | 1985-12-05 | 1991-04-30 | Meiogenics U.S. Limited Partnership | Methods for detecting nucleic acid sequences |
US5403711A (en) | 1987-11-30 | 1995-04-04 | University Of Iowa Research Foundation | Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved |
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US5720928A (en) | 1988-09-15 | 1998-02-24 | New York University | Image processing and analysis of individual nucleic acid molecules |
US6147198A (en) | 1988-09-15 | 2000-11-14 | New York University | Methods and compositions for the manipulation and characterization of individual nucleic acid molecules |
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
US5824477A (en) | 1990-09-12 | 1998-10-20 | Scientific Generics Limited | Electrochemical denaturation of double-stranded nucleic acid |
US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
US6048690A (en) | 1991-11-07 | 2000-04-11 | Nanogen, Inc. | Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis |
US5558998A (en) | 1992-02-25 | 1996-09-24 | The Regents Of The Univ. Of California | DNA fragment sizing and sorting by laser-induced fluorescence |
US5332659A (en) | 1992-04-09 | 1994-07-26 | The United States Of America As Represented By The Secretary Of The Navy | Light emission-or absorbance-based binding assays for polynucleic acids |
JPH06153997A (en) | 1992-11-27 | 1994-06-03 | Canon Inc | Method for detecting target nucleic acid by amplification of detected signal |
US6027880A (en) | 1995-08-02 | 2000-02-22 | Affymetrix, Inc. | Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis |
US5861124A (en) | 1993-07-15 | 1999-01-19 | Hamamatsu Photonics Kk | Method and apparatus for detecting denaturation of nucleic acid |
JPH09506762A (en) | 1993-08-18 | 1997-07-08 | アイディー バイオメディカル コーポレイション | Proximity sequence-compositions and methods for detecting target nucleic acid sequences utilizing enzyme molecules |
DE69431669T2 (en) | 1993-09-02 | 2003-10-23 | Ribozyme Pharmaceuticals, Inc. | ENZYMATIC NUCLEIC ACID THAT CONTAINS NON-NUCLEOTIDS |
US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
AU8102694A (en) | 1993-11-17 | 1995-06-06 | Id Biomedical Corporation | Cycling probe cleavage detection of nucleic acid sequences |
US5998193A (en) | 1994-06-24 | 1999-12-07 | Gene Shears Pty., Ltd. | Ribozymes with optimized hybridizing arms, stems, and loops, tRNA embedded ribozymes and compositions thereof |
JP3189000B2 (en) | 1994-12-01 | 2001-07-16 | 東ソー株式会社 | Specific nucleic acid sequence detection method |
US6426407B1 (en) * | 1995-06-07 | 2002-07-30 | Codon Pharm. | Residues for binding third strands to complementary nucleic acid duplexes of any base pair sequence |
US6001657A (en) * | 1995-10-12 | 1999-12-14 | North Carolina State University | Antibodies that selectively bind quadruplex nucleic acids |
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US6251591B1 (en) | 1997-02-27 | 2001-06-26 | Lorne Park Research, Inc. | Quantitative method for detecting nucleotide concentration |
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US6013442A (en) | 1997-08-05 | 2000-01-11 | Wisconsin Alumni Res Found | Direct quantitation of low copy number RNA |
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US6017709A (en) | 1998-04-29 | 2000-01-25 | University Of Houston | DNA replication templates stabilized by guanine quartets |
US6287765B1 (en) * | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
US6255050B1 (en) | 1998-05-22 | 2001-07-03 | Lorne Park Research, Inc. | Dynamic hybridization system |
GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
GB9821989D0 (en) | 1998-10-08 | 1998-12-02 | Hybaid Ltd | Detection of nucleic acid polymorphism |
US6420115B1 (en) * | 1999-12-21 | 2002-07-16 | Ingeneus Corporation | Cation mediated triplex hybridization assay |
US6403313B1 (en) | 1999-12-21 | 2002-06-11 | Ingeneus Corporation | Fluorescent intensity assay for duplex and triplex nucleic acid hybridization solution utilizing fluorescent intercalators |
US6265170B1 (en) | 2000-01-24 | 2001-07-24 | Ingeneus Corporation | Homogenous assay of duplex of triplex hybridization by means of multiple measurements under varied conditions |
-
2002
- 2002-11-12 US US10/293,148 patent/US7309569B2/en not_active Expired - Fee Related
-
2003
- 2003-09-24 WO PCT/IB2003/005252 patent/WO2004044122A2/en not_active Application Discontinuation
- 2003-09-24 AU AU2003276602A patent/AU2003276602A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5874555A (en) * | 1987-10-30 | 1999-02-23 | California Institute Of Technology | Triple helices and processes for making same |
US5800984A (en) * | 1990-12-17 | 1998-09-01 | Idexx Laboratories, Inc. | Nucleic acid sequence detection by triple helix formation at primer site in amplification reactions |
US5846729A (en) * | 1997-02-27 | 1998-12-08 | Lorne Park Research, Inc. | Assaying nucleotides in solution using a fluorescent intensity quenching effect |
US6287772B1 (en) * | 1998-04-29 | 2001-09-11 | Boston Probes, Inc. | Methods, kits and compositions for detecting and quantitating target sequences |
Also Published As
Publication number | Publication date |
---|---|
AU2003276602A8 (en) | 2004-06-03 |
WO2004044122A2 (en) | 2004-05-27 |
US20050014140A1 (en) | 2005-01-20 |
AU2003276602A1 (en) | 2004-06-03 |
US7309569B2 (en) | 2007-12-18 |
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