WO2004029616A3 - Methods for detecting prostate cancer - Google Patents

Methods for detecting prostate cancer Download PDF

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Publication number
WO2004029616A3
WO2004029616A3 PCT/CA2003/001479 CA0301479W WO2004029616A3 WO 2004029616 A3 WO2004029616 A3 WO 2004029616A3 CA 0301479 W CA0301479 W CA 0301479W WO 2004029616 A3 WO2004029616 A3 WO 2004029616A3
Authority
WO
WIPO (PCT)
Prior art keywords
prostate cancer
methods
detecting prostate
psa
kallikrein
Prior art date
Application number
PCT/CA2003/001479
Other languages
French (fr)
Other versions
WO2004029616A2 (en
Inventor
Eleftherios P Diamandis
Original Assignee
Mount Sinai Hospital Corp
Eleftherios P Diamandis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mount Sinai Hospital Corp, Eleftherios P Diamandis filed Critical Mount Sinai Hospital Corp
Priority to EP03753166A priority Critical patent/EP1546729A2/en
Priority to US10/529,088 priority patent/US20060269971A1/en
Priority to CA002498147A priority patent/CA2498147A1/en
Priority to AU2003271457A priority patent/AU2003271457A1/en
Publication of WO2004029616A2 publication Critical patent/WO2004029616A2/en
Publication of WO2004029616A3 publication Critical patent/WO2004029616A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to the application of kallikrein (11), free PSA, and total PSA in the detection of prostate cancer. These markers may be used for the diagnosis, monitoring, staging, progression, prevention, treatment, and prognosis of prostate cancer, and as indicators before surgery or after relapse. A particular aspect of the invention provides a method for distinguishing prostate cancer from benign prostatic hyperplasia (BPH).
PCT/CA2003/001479 2002-09-26 2003-09-26 Methods for detecting prostate cancer WO2004029616A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP03753166A EP1546729A2 (en) 2002-09-26 2003-09-26 Methods for detecting prostate cancer
US10/529,088 US20060269971A1 (en) 2003-09-26 2003-09-26 Methods for detecting prostate cancer
CA002498147A CA2498147A1 (en) 2002-09-26 2003-09-26 Methods for detecting prostate cancer
AU2003271457A AU2003271457A1 (en) 2002-09-26 2003-09-26 Methods for detecting prostate cancer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41431402P 2002-09-26 2002-09-26
US60/414,314 2002-09-26

Publications (2)

Publication Number Publication Date
WO2004029616A2 WO2004029616A2 (en) 2004-04-08
WO2004029616A3 true WO2004029616A3 (en) 2004-07-15

Family

ID=32043380

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2003/001479 WO2004029616A2 (en) 2002-09-26 2003-09-26 Methods for detecting prostate cancer

Country Status (4)

Country Link
EP (1) EP1546729A2 (en)
AU (1) AU2003271457A1 (en)
CA (1) CA2498147A1 (en)
WO (1) WO2004029616A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104981696B (en) * 2012-12-11 2017-11-24 康奈尔大学 Diagnosis and the method for the treatment of prostate cancer
CN113866412A (en) * 2021-09-07 2021-12-31 山东博科生物产业有限公司 Sensitive total prostate specific antigen detection kit

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002097438A1 (en) * 2001-05-25 2002-12-05 Mount Sinai Hospital Method of detecting and monitoring prostate and ovarian cancers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002097438A1 (en) * 2001-05-25 2002-12-05 Mount Sinai Hospital Method of detecting and monitoring prostate and ovarian cancers

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DIAMANDIS E P ET AL: "HUMAN TISSUE KALLIKREINS: A FAMILY OF NEW CANCER BIOMARKERS", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY. WINSTON, US, vol. 48, no. 8, August 2002 (2002-08-01), pages 1198 - 1205, XP001121702, ISSN: 0009-9147 *
DIAMANDIS ELEFTHERIOS P ET AL: "Human kallikrein 11: A new biomarker of prostate and ovarian carcinoma", CANCER RESEARCH, vol. 62, no. 1, 1 January 2002 (2002-01-01), pages 295 - 300, XP002216344, ISSN: 0008-5472 *
MAGKLARA ANGELIKI ET AL: "The combination of human glandular kallikrein and free prostate-specific antigen (PSA) enhances discrimination between prostate cancer and benign prostatic hyperplasia in patients with moderately increased total PSA", CLINICAL CHEMISTRY, vol. 45, no. 11, November 1999 (1999-11-01), pages 1960 - 1966, XP002273448, ISSN: 0009-9147 *
NAKAMURA T ET AL: "ALTERNATIVE SPLICING ISOFORMS OF HIPPOSTASIN (PRSS20/KLKII) IN PROSTATE CANCER CELL LINES", PROSTATE, WILEY-LISS, NEW YORK, NY, US, vol. 49, no. 1, 15 September 2001 (2001-09-15), pages 72 - 78, XP001105309, ISSN: 0270-4137 *
NAKAMURA TERUKAZU ET AL: "Human kallikrein 11;a new biomarker of prostate cancer", JOURNAL OF UROLOGY, vol. 167, no. 4 Supplement, April 2002 (2002-04-01), Annual Meeting of the American Urology Association, Inc.;Orlando, Florida, USA; May 25-30, 2002, pages 286, XP009027318, ISSN: 0022-5347 *
YOUSEF GEORGE M ET AL: "Expanded human tissue kallikrein family: A novel panel of cancer biomarkers", TUMOR BIOLOGY, vol. 23, no. 3, May 2002 (2002-05-01), pages 185 - 192, XP009027321, ISSN: 1010-4283 *

Also Published As

Publication number Publication date
WO2004029616A2 (en) 2004-04-08
AU2003271457A1 (en) 2004-04-19
AU2003271457A8 (en) 2004-04-19
EP1546729A2 (en) 2005-06-29
CA2498147A1 (en) 2004-04-08

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