WO2004020587A3 - Carboxypeptidase b related polypeptides and methods of use - Google Patents

Carboxypeptidase b related polypeptides and methods of use Download PDF

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Publication number
WO2004020587A3
WO2004020587A3 PCT/US2003/026773 US0326773W WO2004020587A3 WO 2004020587 A3 WO2004020587 A3 WO 2004020587A3 US 0326773 W US0326773 W US 0326773W WO 2004020587 A3 WO2004020587 A3 WO 2004020587A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
carboxypeptidase
related polypeptides
polypeptides
disclosed
Prior art date
Application number
PCT/US2003/026773
Other languages
French (fr)
Other versions
WO2004020587A2 (en
Inventor
Margaret Anne Mccarrick
Michael John Morser
Mariko Nagashima
Lei Zhao
Original Assignee
Schering Ag
Margaret Anne Mccarrick
Michael John Morser
Mariko Nagashima
Lei Zhao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Margaret Anne Mccarrick, Michael John Morser, Mariko Nagashima, Lei Zhao filed Critical Schering Ag
Priority to AU2003262895A priority Critical patent/AU2003262895A1/en
Publication of WO2004020587A2 publication Critical patent/WO2004020587A2/en
Publication of WO2004020587A3 publication Critical patent/WO2004020587A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)

Abstract

Recombinant TAFI polypeptide mutants, as well as the polynucleotides encoding such polypeptides, are disclosed. Also disclosed are methods for utilizing such polypeptides in methods of screening for potential therapeutic agents, substrates, inhibitors or enhancers of carboxypeptidases.
PCT/US2003/026773 2002-08-28 2003-08-25 Carboxypeptidase b related polypeptides and methods of use WO2004020587A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003262895A AU2003262895A1 (en) 2002-08-28 2003-08-25 Carboxypeptidase b related polypeptides and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40634102P 2002-08-28 2002-08-28
US60/406,341 2002-08-28

Publications (2)

Publication Number Publication Date
WO2004020587A2 WO2004020587A2 (en) 2004-03-11
WO2004020587A3 true WO2004020587A3 (en) 2005-01-13

Family

ID=31978288

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/026773 WO2004020587A2 (en) 2002-08-28 2003-08-25 Carboxypeptidase b related polypeptides and methods of use

Country Status (2)

Country Link
AU (1) AU2003262895A1 (en)
WO (1) WO2004020587A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003213676A1 (en) * 2002-03-04 2003-09-22 Bristol-Myers Squibb Company Novel nucleic acid molecules and polypeptides encoding baboon tafi

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474901A (en) * 1991-02-01 1995-12-12 Genentech, Inc. Antibodies to human carboxypeptidase B and methods of use thereof
WO1998055645A1 (en) * 1997-06-03 1998-12-10 Schering Aktiengesellschaft Method of detecting thrombotic disease risk

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474901A (en) * 1991-02-01 1995-12-12 Genentech, Inc. Antibodies to human carboxypeptidase B and methods of use thereof
WO1998055645A1 (en) * 1997-06-03 1998-12-10 Schering Aktiengesellschaft Method of detecting thrombotic disease risk

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EATON ET AL: "Isolation, Molecular Cloning, and Partial Characterization of a Novel CarboxypeptidaseB from Human Plasma", J. BIOL. CHEM., vol. 266, no. 32, 15 November 1991 (1991-11-15), pages 21833 - 21838, XP002928078 *

Also Published As

Publication number Publication date
AU2003262895A1 (en) 2004-03-19
WO2004020587A2 (en) 2004-03-11
AU2003262895A8 (en) 2004-03-19

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