WO2004011449A3 - Verfahren zur herstellung von phenylalanin-derivaten - Google Patents
Verfahren zur herstellung von phenylalanin-derivaten Download PDFInfo
- Publication number
- WO2004011449A3 WO2004011449A3 PCT/EP2003/008230 EP0308230W WO2004011449A3 WO 2004011449 A3 WO2004011449 A3 WO 2004011449A3 EP 0308230 W EP0308230 W EP 0308230W WO 2004011449 A3 WO2004011449 A3 WO 2004011449A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- production
- phenylalanine derivatives
- derivatives
- amidino
- phenylalanine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/522,218 US7247724B2 (en) | 2002-07-25 | 2003-07-25 | Method for the production of phenylalanine derivatives |
EP03771103A EP1525195A2 (de) | 2002-07-25 | 2003-07-25 | Verfahren zur herstellung von phenylalanin-derivaten |
AU2003253326A AU2003253326A1 (en) | 2002-07-25 | 2003-07-25 | Method for the production of phenylalanine derivatives |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10233919 | 2002-07-25 | ||
DE10233919.8 | 2002-07-25 | ||
DE10238048A DE10238048A1 (de) | 2002-07-25 | 2002-08-20 | Verfahren zur Herstellung von Phenylalanin-Derivaten |
DE10238048.1 | 2002-08-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004011449A2 WO2004011449A2 (de) | 2004-02-05 |
WO2004011449A3 true WO2004011449A3 (de) | 2004-04-08 |
Family
ID=31189298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/008230 WO2004011449A2 (de) | 2002-07-25 | 2003-07-25 | Verfahren zur herstellung von phenylalanin-derivaten |
Country Status (4)
Country | Link |
---|---|
US (1) | US7247724B2 (de) |
EP (1) | EP1525195A2 (de) |
AU (1) | AU2003253326A1 (de) |
WO (1) | WO2004011449A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7504425B2 (en) | 2002-05-29 | 2009-03-17 | Merck & Co., Inc. | Compounds useful in the treatment of anthrax and inhibiting lethal factor |
DE10323898A1 (de) * | 2003-05-26 | 2004-12-23 | Wilex Ag | Hydroxyamidin- und Hydroxyguanidin-Verbindungen als Urokinase-Hemmstoffe |
CN1950354A (zh) | 2004-05-11 | 2007-04-18 | 默克公司 | N-磺酰化-氨基酸衍生物的制备方法 |
DE102004045720A1 (de) * | 2004-09-21 | 2006-03-23 | Wilex Ag | Stabile Dosierungsform von Phenylalanin-Derivaten |
DE102004057195A1 (de) | 2004-11-26 | 2006-06-01 | Wilex Ag | Kristalline Modifikationen von N-Alpha-(2,4,6-Triisopropylphenylsulfonyl)-3-hydroxyamidino-(L)-phenylalanin-4-ethoxycarbonylpiperazid und/oder Salzen davon |
AU2021235304A1 (en) | 2020-03-10 | 2022-10-06 | Redhill Biopharma Ltd. | Treatment of coronavirus infection |
US11471448B2 (en) | 2020-12-15 | 2022-10-18 | Redhill Biopharma Ltd. | Sphingosine kinase 2 inhibitor for treating coronavirus infection in moderately severe patients with pneumonia |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992008709A1 (de) * | 1990-11-15 | 1992-05-29 | Pentapharm Ag | Meta-substituierte phenylalanin-derivate |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2189455T3 (es) * | 1998-07-20 | 2003-07-01 | Wilex Ag | Nuevos agentes inhibidores de la urocinasa. |
DE10117381A1 (de) | 2001-04-06 | 2002-10-10 | Wilex Biotechnology Gmbh | Herstellung polyklonaler, monospezifischer Antikörper gegen die uPAR-Varianten del4, del5 und del4+5 sowie deren Verwendung für diagnostische und therapeutische Zwecke |
-
2003
- 2003-07-25 AU AU2003253326A patent/AU2003253326A1/en not_active Abandoned
- 2003-07-25 WO PCT/EP2003/008230 patent/WO2004011449A2/de not_active Application Discontinuation
- 2003-07-25 US US10/522,218 patent/US7247724B2/en not_active Expired - Lifetime
- 2003-07-25 EP EP03771103A patent/EP1525195A2/de not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992008709A1 (de) * | 1990-11-15 | 1992-05-29 | Pentapharm Ag | Meta-substituierte phenylalanin-derivate |
Non-Patent Citations (2)
Title |
---|
LEE K ET AL: "Fluorobenzamidrazone Thrombin Inhibitors: Influence of Fluorine on Enhancing Oral Absorption", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 9, no. 17, 6 September 1999 (1999-09-06), pages 2483 - 2486, XP004188848, ISSN: 0960-894X * |
STURZEBECHER J ET AL: "3-Amidinophenylalanine-based Inhibitors of Urokinase", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 9, no. 21, 1 November 1999 (1999-11-01), pages 3147 - 3152, XP004181024, ISSN: 0960-894X * |
Also Published As
Publication number | Publication date |
---|---|
WO2004011449A2 (de) | 2004-02-05 |
US20050245757A1 (en) | 2005-11-03 |
EP1525195A2 (de) | 2005-04-27 |
US7247724B2 (en) | 2007-07-24 |
AU2003253326A1 (en) | 2004-02-16 |
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